Rachael Thomas
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Works (49)
Updated: July 13th, 2023 21:18
2023 journal article
The dogs of Chernobyl: Demographic insights into populations inhabiting the nuclear exclusion zone
SCIENCE ADVANCES, 9(9).
co-author countries:
China 🇨🇳 Poland 🇵🇱 Ukraine 🇺🇦 United States of America 🇺🇸
MeSH headings : Dogs; Animals; Chernobyl Nuclear Accident; Environment; Disasters; Environmental Pollution; Demography
www.science.org (publisher PDF)
Source: Web Of Science
Added: April 4, 2023
2023 journal article
Whole exome sequencing analysis of canine urothelial carcinomas without BRAF V595E mutation: Short in-frame deletions in BRAF and MAP2K1 suggest alternative mechanisms for MAPK pathway disruption
PLOS GENETICS, 19(4).
co-author countries:
United States of America 🇺🇸
MeSH headings : Dogs; Animals; Humans; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / veterinary; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / veterinary; Proto-Oncogene Proteins B-raf / genetics; Exome Sequencing; Mutation; MAP Kinase Kinase 1 / genetics
Sources: Web Of Science, ORCID
Added: May 15, 2023
2022 journal article
The AGMK1-9T7 cell model of neoplasia: Evolution of DNA copy-number aberrations and miRNA expression during transition from normal to metastatic cancer cells
PLOS ONE, 17(10).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Humans; Chlorocebus aethiops; MicroRNAs / genetics; MicroRNAs / metabolism; Neoplasms / genetics; Carcinogenesis / genetics; DNA Copy Number Variations / genetics; Chromosome Aberrations; Neoplasms, Second Primary / genetics; DNA; Gene Expression Regulation, Neoplastic; Gene Expression Profiling
Source: Web Of Science
Added: February 27, 2023
2021 journal article
Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions
MOLECULAR CANCER RESEARCH, 19(5), 847–861.
co-author countries:
Canada 🇨🇦 Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Animals; Dog Diseases / genetics; Dogs; Gene Expression Profiling / methods; Gene Fusion; Genomics / methods; Hemangiosarcoma / genetics; Humans; Transcription, Genetic; Vascular Neoplasms / genetics
Source: Web Of Science
Added: June 10, 2021
2020 article
A comparative oncology approach to biomarker and drug discovery for cancer diagnosis and treatment in dogs and humans
LeBlanc, A. K., Mazcko, C. N., Breen, M., Thomas, R., & Thamm, D. H. (2020, August). CANCER RESEARCH, Vol. 80.
Source: Web Of Science
Added: March 8, 2021
2020 journal article
Development of a Genome-Wide Oligonucleotide Microarray Platform for Detection of DNA Copy Number Aberrations in Feline Cancers
VETERINARY SCIENCES, 7(3).
co-author countries:
United States of America 🇺🇸
author keywords: feline; cat; cancer; genomics; chromosome; comparative genomic hybridization (CGH)
Sources: Web Of Science, ORCID
Added: November 9, 2020
2020 article
Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma
Kim, J. H., Megquier, K., Sarver, A. L., Thomas, R., Schulte, A. J., Wang, C., … Modiano, J. F. (2020, August). CANCER RESEARCH, Vol. 80.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
Source: Web Of Science
Added: March 8, 2021
2019 journal article
Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma
MOLECULAR CANCER RESEARCH, 17(12), 2410–2421.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Animals; Blood Vessels / pathology; Breast / metabolism; Breast / pathology; Class I Phosphatidylinositol 3-Kinases / genetics; Class Ia Phosphatidylinositol 3-Kinase / genetics; Cyclin-Dependent Kinase Inhibitor p15 / genetics; Cyclin-Dependent Kinase Inhibitor p16 / genetics; Dogs; Female; Genome / genetics; Genomics; Hemangiosarcoma / genetics; Hemangiosarcoma / pathology; Humans; Mutation / genetics; Tumor Suppressor Protein p53 / genetics; Viscera / metabolism; Viscera / pathology; Exome Sequencing
Sources: Web Of Science, ORCID
Added: December 30, 2019
2019 journal article
Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex
CHROMOSOME RESEARCH, 27(3), 179–202.
co-author countries:
United States of America 🇺🇸
author keywords: Histiocytic sarcoma; Chromothripsis; MMP9; Aurora kinase; Dendritic cell sarcoma
MeSH headings : Animals; Chromosome Disorders; DNA Copy Number Variations / genetics; Dog Diseases / diagnosis; Dog Diseases / genetics; Dogs; Gene Expression Profiling; Genome / genetics; Histiocytic Disorders, Malignant / diagnosis; Histiocytic Disorders, Malignant / genetics; Histiocytic Disorders, Malignant / veterinary; Humans; Immunohistochemistry / methods; Matrix Metalloproteinase 9 / metabolism; Spindle Apparatus / pathology
Source: Web Of Science
Added: September 30, 2019
2018 article
Mutational and transcriptomic profiling identify distinct angiogenic and inflammatory subtypes of angiosarcoma
Kim, J. H., Megquier, K., Sarver, A. L., Thomas, R., Wang, C., Elvers, I., … Modiano, J. F. (2018, July). CANCER RESEARCH, Vol. 78.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
Source: Web Of Science
Added: June 24, 2019
2017 journal article
Evaluation of gene expression and DNA copy number profiles of adipose tissue-derived stromal cells and consecutive neurosphere-like cells generated from dogs with naturally occurring spinal cord injury
American Journal of Veterinary Research, 78(3), 371–380.
MeSH headings : Adipose Tissue / cytology; Animals; Cells, Cultured; Comparative Genomic Hybridization; Dogs; Female; Gene Dosage / genetics; Gene Expression Profiling; Gene Expression Regulation; Male; Neural Stem Cells / cytology; Neural Stem Cells / pathology; Neurons / cytology; Neurons / pathology; Proteins / genetics; Spinal Cord Injuries / physiopathology; Spinal Cord Injuries / veterinary; Stromal Cells / cytology; Stromal Cells / physiology
Sources: NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2017 journal article
Genomic profiling of canine mast cell tumors identifies DNA copy number aberrations associated with KIT mutations and high histological grade
CHROMOSOME RESEARCH, 25(2), 129–143.
co-author countries:
United States of America 🇺🇸
author keywords: Cancer; Comparative genomic hybridization; Digital PCR; Dog; Mastocytosis; Pug
MeSH headings : Animals; Comparative Genomic Hybridization; DNA Copy Number Variations / genetics; Dogs; Genome / genetics; Mastocytosis, Cutaneous / diagnosis; Mastocytosis, Cutaneous / genetics; Mastocytosis, Cutaneous / pathology; Mutation; Predictive Value of Tests; Proto-Oncogene Proteins c-kit / genetics; Sensitivity and Specificity
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma
VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 852–867.
co-author countries:
United States of America 🇺🇸
author keywords: BCL2; canine; comparative genomic hybridization; fluorescence in situ hybridization; follicular lymphoma; immunohistochemistry
MeSH headings : Animals; DNA Copy Number Variations / genetics; DNA Fingerprinting / veterinary; Dog Diseases / etiology; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genome-Wide Association Study / veterinary; Lymphoma, Follicular / etiology; Lymphoma, Follicular / genetics; Lymphoma, Follicular / pathology; Lymphoma, Follicular / veterinary; Male; Risk Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity
CHROMOSOME RESEARCH, 23(4), 663–680.
co-author countries:
United States of America 🇺🇸
author keywords: Neoplastic transformation; Tumorigenicity; Canine chromosomes; Comparative genomic hybridization (CGH); Fluorescence in situ hybridization (FISH); Madin-Darby canine kidney (MDCK) cell line; CKB1-3T7 cell line
MeSH headings : Animals; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic / genetics; Cells, Cultured; Chromosome Aberrations; DNA Copy Number Variations; Dogs; In Situ Hybridization, Fluorescence; Karyotype; Madin Darby Canine Kidney Cells; Male; Neoplasms / genetics; Neoplasms / pathology
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Canine Prostate Cancer Cell Line (Probasco) Produces Osteoblastic Metastases In Vivo
PROSTATE, 74(13), 1251–1265.
co-author countries:
United States of America 🇺🇸
author keywords: prostate cancer; osteoblastic metastases; canine; dog
MeSH headings : Animals; Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Bone Neoplasms / genetics; Bone Neoplasms / metabolism; Bone Neoplasms / secondary; Carcinoma / genetics; Carcinoma / metabolism; Carcinoma / secondary; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dogs; Male; Mice; Mice, Nude; Neoplasm Transplantation; Osteoblasts / metabolism; Osteoblasts / pathology; Prostatic Neoplasms / genetics; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma
CHROMOSOME RESEARCH, 22(3), 305–319.
co-author countries:
Sweden 🇸🇪 United States of America 🇺🇸
author keywords: canine; chromosome; hemangiosarcoma; comparative genomic hybridization (CGH)
MeSH headings : Animals; Breeding; Comparative Genomic Hybridization; DNA Copy Number Variations / genetics; Dog Diseases / genetics; Dogs; Gene Amplification; Gene Expression Profiling; Genetic Heterogeneity; Genome; Hemangiosarcoma / genetics; Hemangiosarcoma / veterinary; Penetrance; Vascular Endothelial Growth Factor A / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Growth Requirements and Chromosomal Instability of Induced Pluripotent Stem Cells Generated from Adult Canine Fibroblasts
Stem Cells and Development, 22(6), 951–963.
co-author countries:
United States of America 🇺🇸
MeSH headings : Alkaline Phosphatase / metabolism; Animals; Antigens, Differentiation / genetics; Antigens, Differentiation / metabolism; Cell Differentiation; Cell Shape; Cells, Cultured; Chromosomal Instability; Coculture Techniques; Comparative Genomic Hybridization; Dogs; Fibroblasts / physiology; Gene Expression; In Situ Hybridization, Fluorescence; Induced Pluripotent Stem Cells / enzymology; Induced Pluripotent Stem Cells / pathology; Induced Pluripotent Stem Cells / transplantation; Kruppel-Like Factor 4; Mice; Mice, SCID; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Teratoma / genetics; Teratoma / pathology; Transcription Factors / biosynthesis; Transcription Factors / genetics
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2013 article
Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine
Rotroff, D. M., Thomas, R., Breen, M., & Motsinger-Reif, A. A. (2013, December). PHARMACOGENOMICS, Vol. 14, pp. 1929–1931.
co-author countries:
United States of America 🇺🇸
author keywords: cancer; canine model; chemotherapy; clinical trials
MeSH headings : Animals; Disease Models, Animal; Dogs; Humans; Neoplasms / drug therapy; Neoplasms / pathology; Pharmacogenetics / methods
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas
Cancer, 118(23), 5878–5887.
co-author countries:
France 🇫🇷 United States of America 🇺🇸
author keywords: angiosarcoma; p53; phosphoinositide-3-kinase; catalytic; alpha polypeptide; phosphatase and tensin homolog; complex karyotype
MeSH headings : Adult; Aged; Aged, 80 and over; Class I Phosphatidylinositol 3-Kinases; Female; Genes, p53; Genomics; Hemangiosarcoma / etiology; Hemangiosarcoma / genetics; Humans; Male; Middle Aged; Mutation; PTEN Phosphohydrolase / genetics; Phosphatidylinositol 3-Kinases / physiology; Proto-Oncogene Proteins B-raf / genetics; Proto-Oncogene Proteins c-akt / physiology; Proto-Oncogene Proteins c-mdm2 / analysis; Signal Transduction / physiology; TOR Serine-Threonine Kinases / physiology
Source: Crossref
Added: June 6, 2020
2012 journal article
CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies
LEUKEMIA & LYMPHOMA, 53(7), 1390–1398.
co-author countries:
United States of America 🇺🇸
author keywords: Diffuse large B-cell lymphoma; CD40L; primary cell culture; canine model; cytotoxicity assay
MeSH headings : Animals; CD40 Ligand / genetics; CD40 Ligand / metabolism; CD40 Ligand / pharmacology; Cell Culture Techniques / methods; Cell Proliferation / drug effects; Cell Survival / drug effects; Coculture Techniques; Dogs; Dose-Response Relationship, Drug; Feeder Cells / metabolism; Gene Expression Profiling; Humans; Lymphoma, Large B-Cell, Diffuse / genetics; Lymphoma, Large B-Cell, Diffuse / metabolism; Lymphoma, Large B-Cell, Diffuse / pathology; Oligonucleotide Array Sequence Analysis; Recombinant Proteins / pharmacology; Tumor Cells, Cultured
Source: Web Of Science
Added: August 6, 2018
2012 conference paper
Generation and characterization of induced pluripotent stem cells (iPS) from adult canine fibroblasts
Reproduction in Domestic Animals, 47, 418–419.
Source: NC State University Libraries
Added: August 6, 2018
2012 journal article
The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification
GENES CHROMOSOMES & CANCER, 51(6), 569–578.
co-author countries:
United States of America 🇺🇸
MeSH headings : Adult; Aged; Aged, 80 and over; Comparative Genomic Hybridization; DNA-Binding Proteins / biosynthesis; DNA-Binding Proteins / genetics; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, myc; Hemangiosarcoma / chemistry; Hemangiosarcoma / genetics; Hemangiosarcoma / metabolism; Humans; In Situ Hybridization, Fluorescence; Male; MicroRNAs / biosynthesis; MicroRNAs / genetics; Middle Aged; Proto-Oncogene Proteins c-myc / biosynthesis; Proto-Oncogene Proteins c-myc / genetics; RNA, Long Noncoding; Sequence Analysis, RNA; Thrombospondin 1 / biosynthesis; Thrombospondin 1 / genetics; Transcription Factors / biosynthesis; Transcription Factors / genetics; Vascular Neoplasms / chemistry; Vascular Neoplasms / genetics; Vascular Neoplasms / metabolism
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Anchoring the dog to its relatives reveals new evolutionary breakpoints across 11 species of the Canidae and provides new clues for the role of B chromosomes
CHROMOSOME RESEARCH, 19(6), 685–708.
co-author countries:
Russian Federation 🇷🇺 United States of America 🇺🇸
author keywords: B chromosomes; fragile breakage model; breakpoint reuse theory; fluorescence in situ hybridization; phylogenetic; Canidae
MeSH headings : Animals; Biological Evolution; Canidae / genetics; Chromosome Mapping; Chromosome Painting; Chromosomes, Artificial, Bacterial; Chromosomes, Mammalian / genetics; Cytogenetics; Dogs / genetics; Foxes / genetics; Genome; In Situ Hybridization, Fluorescence; Raccoon Dogs / genetics
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Characterization of Canine Osteosarcoma by Array Comparative Genomic Hybridization and RT-qPCR: Signatures of Genomic Imbalance in Canine Osteosarcoma Parallel the Human Counterpart
GENES CHROMOSOMES & CANCER, 50(11), 859–874.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Bone Neoplasms / genetics; Bone Neoplasms / veterinary; Comparative Genomic Hybridization; Core Binding Factor Alpha 1 Subunit / genetics; DNA Copy Number Variations; Dog Diseases / genetics; Dogs; Female; Gene Dosage; Genomic Instability; Humans; In Situ Hybridization, Fluorescence; Male; Membrane Proteins / genetics; Osteosarcoma / genetics; Osteosarcoma / veterinary; PTEN Phosphohydrolase / genetics; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Tumor Suppressor Proteins / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2011 journal article
FLT3 mutations in canine acute lymphocytic leukemia
BMC CANCER, 11.
co-author countries:
United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; Blotting, Western; Carbazoles / pharmacology; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; DNA Mutational Analysis; DNA, Neoplasm / chemistry; DNA, Neoplasm / genetics; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases / metabolism; Furans; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Mutation; Phosphorylation / drug effects; Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism; Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology; Reverse Transcriptase Polymerase Chain Reaction; STAT5 Transcription Factor / metabolism; fms-Like Tyrosine Kinase 3 / antagonists & inhibitors; fms-Like Tyrosine Kinase 3 / genetics; fms-Like Tyrosine Kinase 3 / metabolism
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Reading between the lines: molecular characterization of five widely used canine lymphoid tumour cell lines
Veterinary and Comparative Oncology, 11(1), 30–50.
co-author countries:
United States of America 🇺🇸
author keywords: canine; cell line; comparative; lymphoid neoplasia; microarray; model
MeSH headings : Animals; Cell Line, Tumor; DNA / genetics; DNA / metabolism; Dog Diseases / metabolism; Dogs; Flow Cytometry; Gene Expression Regulation, Neoplastic / physiology; Karyotype; Lymphoma / metabolism; Neoplasm Proteins / genetics; Neoplasm Proteins / metabolism; RNA / genetics; RNA / metabolism; Real-Time Polymerase Chain Reaction / veterinary; Transcriptome
Sources: Web Of Science, Crossref
Added: August 6, 2018
2011 journal article
Refining tumor-associated aneuploidy through ‘genomic recoding’ of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas
Leukemia & Lymphoma, 52(7), 1321–1335.
author keywords: Comparative genomic hybridization (CGH); canine; lymphoma; chromosome; microarray
MeSH headings : Aneuploidy; Animals; Breeding; Comparative Genomic Hybridization; Cyclin-Dependent Kinase Inhibitor p16 / genetics; DNA Copy Number Variations / genetics; Dogs; Gene Expression Regulation, Neoplastic; Genomics; Immunophenotyping; Lymphoma, Non-Hodgkin / genetics; Lymphoma, Non-Hodgkin / pathology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2009 journal article
Extensive conservation of genomic imbalances in canine transmissible venereal tumors (CTVT) detected by microarray-based CGH analysis
CHROMOSOME RESEARCH, 17(7), 927–934.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: comparative genomic hybridization (CGH); canine; transmissible venereal tumor; chromosome; microarray
MeSH headings : Animals; Comparative Genomic Hybridization; DNA Copy Number Variations; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / transmission; Dogs; Female; Gene Expression Regulation, Neoplastic; Genome; Male; Oligonucleotide Array Sequence Analysis; Venereal Tumors, Veterinary / genetics; Venereal Tumors, Veterinary / immunology
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Generation and characterization of novel canine malignant mast cell line CL1
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 127(1-2), 114–124.
co-author countries:
United States of America 🇺🇸
author keywords: Mast cell tumor; KIT; Cell line
MeSH headings : Animals; Base Sequence; Cell Degranulation; Cell Line, Tumor; DNA Primers / genetics; DNA, Neoplasm / genetics; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; Genome-Wide Association Study; Immunophenotyping; Mast Cells / immunology; Mast Cells / pathology; Mast Cells / physiology; Mastocytosis, Systemic / genetics; Mastocytosis, Systemic / immunology; Mastocytosis, Systemic / pathology; Mastocytosis, Systemic / veterinary; Proto-Oncogene Proteins c-kit / genetics; Proto-Oncogene Proteins c-kit / metabolism
Source: Web Of Science
Added: August 6, 2018
2009 journal article
IDH1 and IDH2 hotspot mutations are not found in canine glioma
International Journal of Cancer, 127(1), 245–246.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Brain Neoplasms / genetics; Brain Neoplasms / veterinary; Dogs; Glioma / genetics; Glioma / veterinary; Isocitrate Dehydrogenase / genetics; Isoenzymes / genetics; Mutation
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2009 journal article
Influence of genetic background on tumor karyotypes: Evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma
CHROMOSOME RESEARCH, 17(3), 365–377.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: microarray; comparative genomic hybridization (CGH); canine; osteosarcoma; chromosome
MeSH headings : Animals; Chromosome Aberrations / veterinary; Comparative Genomic Hybridization; Dog Diseases / genetics; Dogs; Genetic Predisposition to Disease / genetics; Karyotyping / veterinary; Osteosarcoma / genetics; Osteosarcoma / veterinary; Species Specificity
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Microarray-based cytogenetic profiling reveals recurrent and subtype-associated genomic copy number aberrations in feline sarcomas
CHROMOSOME RESEARCH, 17(8), 987–1000.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 Sweden 🇸🇪 United States of America 🇺🇸
author keywords: microarray; comparative genomic hybridization (CGH); feline; sarcoma; chromosome
MeSH headings : Animals; Cat Diseases / diagnosis; Cats; Cytogenetic Analysis; DNA Copy Number Variations; Gene Dosage; Gene Expression Profiling; Injections / adverse effects; Oligonucleotide Array Sequence Analysis; Sarcoma / diagnosis; Sarcoma / genetics; Sarcoma / veterinary
Source: Web Of Science
Added: August 6, 2018
2009 journal article
ORIGINS AND EVOLUTION OF A TRANSMISSIBLE CANCER
EVOLUTION, 63(9), 2340–2349.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Chromosomal evolution; evolutionary genomics; genetic variation; molecular evolution; population genetics; sex
MeSH headings : Animals; Biological Evolution; Comparative Genomic Hybridization / methods; Dog Diseases / genetics; Dogs / classification; Dogs / genetics; Gene Dosage; Genotype; Microarray Analysis; Microsatellite Repeats / genetics; Neoplasms / genetics; Neoplasms / veterinary; Phylogeny; Venereal Tumors, Veterinary / genetics; Wolves / genetics
Source: Web Of Science
Added: August 6, 2018
2009 journal article
‘Putting our heads together’: insights into genomic conservation between human and canine intracranial tumors
Journal of Neuro-Oncology, 94(3), 333–349.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Comparative genomic hybridization; Canine; Brain tumor; Chromosome; Microarray
MeSH headings : Animals; Brain Neoplasms / genetics; Brain Neoplasms / pathology; Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 22; Cluster Analysis; Dogs; Female; Gene Expression Regulation, Neoplastic; Genome / genetics; Glioma / genetics; Glioma / pathology; Humans; In Situ Hybridization, Fluorescence; Male; Meningeal Neoplasms / genetics; Meningeal Neoplasms / pathology; Meningioma / genetics; Meningioma / pathology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2008 journal article
A genome assembly-integrated dog 1 Mb BAC microarray: a cytogenetic resource for canine cancer studies and comparative genomic analysis
CYTOGENETIC AND GENOME RESEARCH, 122(2), 110–121.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Animals; Chromosomes / genetics; Comparative Genomic Hybridization; Cytogenetics; Databases, Nucleic Acid; Dogs; Genome / genetics; In Situ Hybridization, Fluorescence; Neoplasms / genetics; Oligonucleotide Array Sequence Analysis
Source: Web Of Science
Added: August 6, 2018
2007 article
A cytogenetically characterized, genome-anchored 10-Mb BAC set and CGH array for the domestic dog
JOURNAL OF HEREDITY, Vol. 98, pp. 474–484.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Animals; Chromosome Mapping; Chromosomes, Artificial, Bacterial / genetics; Dogs / genetics; Genome; In Situ Hybridization, Fluorescence; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Sensitivity and Specificity
Source: Web Of Science
Added: August 6, 2018
2007 journal article
A novel canine lymphoma cell line: A translational and comparative model for lymphoma research
LEUKEMIA RESEARCH, 31(12), 1709–1720.
co-author countries:
United States of America 🇺🇸
author keywords: canine lymphoma; cell line; array comparative genomic hybridization; bioluminescent imaging; xenograft
MeSH headings : Animals; Biomedical Research; Cell Line, Tumor; Dogs; Immunophenotyping; Lymphoma / pathology; Mice; Mice, SCID; Neoplasm Transplantation; Transplantation, Heterologous
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-Cell lymphoma
VETERINARY PATHOLOGY, 44(4), 467–478.
co-author countries:
United States of America 🇺🇸
author keywords: canines; cell cycle; non-Hodgkin's lymphoma; tumor suppressor genes
MeSH headings : Animals; Cyclin-Dependent Kinase Inhibitor p16 / genetics; Cyclin-Dependent Kinase Inhibitor p16 / metabolism; Dog Diseases / metabolism; Dogs; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Lymphoma, B-Cell / metabolism; Lymphoma, B-Cell / veterinary; Lymphoma, T-Cell / metabolism; Lymphoma, T-Cell / veterinary; Male; Retinoblastoma Protein / genetics; Retinoblastoma Protein / metabolism
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors
GENOME RESEARCH, 15(12), 1831–1837.
co-author countries:
France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸 South Africa 🇿🇦
MeSH headings : Animals; Cell Line, Tumor; Chromosomes, Artificial, Bacterial / genetics; Cloning, Molecular; Dogs; Genomic Library; In Situ Hybridization, Fluorescence; Nucleic Acid Hybridization / methods; Osteosarcoma / genetics; Osteosarcoma / pathology
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk
CANCER RESEARCH, 65(13), 5654–5661.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; B-Lymphocytes / pathology; Dog Diseases / epidemiology; Dog Diseases / genetics; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Hodgkin Disease / epidemiology; Hodgkin Disease / genetics; Hodgkin Disease / immunology; Hodgkin Disease / pathology; Immunophenotyping; Lymphoproliferative Disorders / epidemiology; Lymphoproliferative Disorders / genetics; Lymphoproliferative Disorders / immunology; Lymphoproliferative Disorders / veterinary; Nucleic Acid Hybridization; Prevalence; T-Lymphocytes / pathology
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Genome sequence, comparative analysis and haplotype structure of the domestic dog
Nature, 438(7069), 803–819.
MeSH headings : Animals; Conserved Sequence / genetics; Dog Diseases / genetics; Dogs / classification; Dogs / genetics; Evolution, Molecular; Female; Genome / genetics; Genomics; Haplotypes / genetics; Humans; Hybridization, Genetic; Male; Mice; Mutagenesis / genetics; Polymorphism, Single Nucleotide / genetics; Rats; Short Interspersed Nucleotide Elements / genetics; Synteny / genetics
Sources: Web Of Science, Crossref
Added: August 6, 2018
2005 journal article
Junctional epidermolysis bullosa in two domestic shorthair kittens
VETERINARY DERMATOLOGY, 16(1), 69–73.
co-author countries:
France 🇫🇷 United States of America 🇺🇸
Contributors: Z. Alhaidari, T. Olivry n , A. Spadafora*, *, C. Perrin *, G. Meneguzzi *, J. Ortonne*
MeSH headings : Animals; Cat Diseases / pathology; Cats; Epidermolysis Bullosa, Junctional / pathology; Epidermolysis Bullosa, Junctional / ultrastructure; Epidermolysis Bullosa, Junctional / veterinary; Female; Fluorescent Antibody Technique, Indirect / veterinary; Immunoenzyme Techniques / veterinary; Laminin / biosynthesis; Male; Microscopy, Electron / veterinary
Sources: Web Of Science, ORCID
Added: August 6, 2018
2005 journal article
Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma
VETERINARY PATHOLOGY, 42(5), 618–632.
co-author countries:
United States of America 🇺🇸
author keywords: canine; endothelial cells; hemangiosarcoma; mutations; PTEN; tumor progression
MeSH headings : Amino Acid Sequence; Animals; Cell Line; Dog Diseases / genetics; Dogs; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hemangiosarcoma / genetics; Hemangiosarcoma / veterinary; Molecular Sequence Data; Mutation / genetics; PTEN Phosphohydrolase / chemistry; PTEN Phosphohydrolase / genetics; Sequence Homology, Amino Acid
Source: Web Of Science
Added: August 6, 2018
2004 journal article
A high-resolution comparative map of canine Chromosome 5q14.3-q33 constructed utilizing the 1.5x canine genomesequence
Mammalian Genome, 15(7), 544–551.
co-author countries:
France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Norway 🇳🇴 United States of America 🇺🇸
MeSH headings : Animals; Chromosome Mapping; Chromosomes / ultrastructure; Chromosomes, Artificial, Bacterial; Crosses, Genetic; DNA / metabolism; DNA Primers / chemistry; Dogs; Gene Library; Genetic Linkage; Genetic Predisposition to Disease; Genome; Genome, Human; Genotype; Humans; Microsatellite Repeats; Models, Genetic; Polymorphism, Single Nucleotide; Species Specificity
Sources: Crossref, Web Of Science
Added: August 6, 2018
2004 journal article
An integrated 4249 marker FISH/RH map of the canine genome
BMC GENOMICS, 5.
co-author countries:
France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Animals; Chromosome Mapping / methods; Chromosomes, Artificial, Bacterial; Dogs / genetics; Genetic Markers; Genome; Humans; In Situ Hybridization, Fluorescence; Microsatellite Repeats; Radiation Hybrid Mapping; Synteny
Source: Web Of Science
Added: August 6, 2018
journal article
Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background
Elvers, I., Turner-Maier, J., Swofford, R., Koltookian, M., Johnson, J., Stewart, C., … Lindblad-Toh, K. Genome Research, 25(11), 1634–1645.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B
Karlsson, E. K., Sigurdsson, S., Ivansson, E., Thomas, R., Elvers, I., Wright, J., … Rivera, P. Genome Biology, 14(12).
Source: NC State University Libraries
Added: August 6, 2018
journal article
Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers
Tonomura, N., Elvers, I., Thomas, R., Megquier, K., Turner-Maier, J., Howald, C., … Kim, J. H. PLoS Genetics, 11(2).
Source: NC State University Libraries
Added: August 6, 2018
journal article
SETD2 is recurrently mutated in whole-exome sequenced canine osteosarcoma
Sakthikumar, S., Elvers, I., Kim, J., Arendt, M. L., Thomas, R., Turner-Maier, J., … Modiano, J. F. Cancer Research, 78(13), 3421–3431.
Source: NC State University Libraries
Added: August 6, 2018
