Richard W. Litaker

author keywords: innate immunity; extra-erythrocytic; hemoglobin; stage-specific activity; Ichthyophthirius multifiliis

MeSH headings : Amino Acid Sequence; Animals; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / isolation & purification; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacology; Antiprotozoal Agents / chemistry; Antiprotozoal Agents / isolation & purification; Antiprotozoal Agents / metabolism; Antiprotozoal Agents / pharmacology; Catfishes / metabolism; Epithelium / metabolism; Gills / metabolism; Gram-Negative Bacteria / drug effects; Hemoglobins / chemistry; Hemoglobins / isolation & purification; Hemoglobins / metabolism; Hemoglobins / pharmacology; Hemolysis / drug effects; Immunohistochemistry; In Situ Hybridization; Molecular Sequence Data; Organ Specificity; Peptides / chemistry; Peptides / isolation & purification; Peptides / metabolism; Peptides / pharmacology; Skin / metabolism; Spectrometry, Mass, Electrospray Ionization; Up-Regulation

TL;DR: Inducible expression and upregulation of antimicrobial peptides homologous to Hbbeta in the gill epithelium of channel catfish in response to parasitic infection suggest that hemoglobin-derived AMPs might play a significant role in the non-specific immune response. (via Semantic Scholar)