Works (12)

Updated: July 25th, 2023 21:16

2012 journal article

Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems

DRUG AND CHEMICAL TOXICOLOGY, 35(3), 310–315.

author keywords: 2-aminoimidazole; adjuvant; biofilm; Caenorhabditis elegans; toxicity; Toxicity of 2-aminoimidazole; antibiofilm agents
MeSH headings : Adjuvants, Pharmaceutic / toxicity; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / toxicity; Biofilms / drug effects; Caenorhabditis elegans; Cell Line; Dose-Response Relationship, Drug; Environmental Exposure; Fertility / drug effects; Humans; Imidazoles / pharmacology; Imidazoles / toxicity; Keratinocytes / metabolism; Tetrazolium Salts; Thiazoles; Toxicity Tests
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Foliar-Applied Small Molecule that Suppresses Biofilm Formation and Enhances Control of Copper-Resistant Xanthomonas euvesicatoria on Pepper

PLANT DISEASE, 96(11), 1638–1644.

By: R. Worthington, S. Rogers*, R. Huigens*, C. Melander* & D. Ritchie n

Source: Web Of Science
Added: August 6, 2018

2011 journal article

Synthesis and biological evaluation of 2-aminoimidazole/carbamate hybrid anti-biofilm and anti-microbial agents

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 21(4), 1257–1260.

By: S. Rogers n, E. Lindsey n, D. Whitehead n, T. Mullikin n & C. Melander n

author keywords: Biofilms; Anti-biofilm; Antibiotic; 2-Aminoimidazole; Menthyl carbamate
Source: Web Of Science
Added: August 6, 2018

2010 journal article

A nitroenolate approach to the synthesis of 4,5-disubstituted-2-aminoimidazoles. Pilot library assembly and screening for antibiotic and antibiofilm activity

Organic & Biomolecular Chemistry, 8(12), 2814–2822.

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Chemical Synthesis and Biological Screening of 2-Aminoimidazole-Based Bacterial and Fungal Antibiofilm Agents

CHEMBIOCHEM, 11(3), 396–410.

By: S. Rogers n, J. Bero n & C. Melander n

author keywords: aminoimidazoles; biofilms; MDRAB; MRSA; multidrug-resistant bacteria
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Antifungal Agents / chemical synthesis; Antifungal Agents / chemistry; Antifungal Agents / pharmacology; Biofilms / drug effects; Drug Resistance, Multiple, Bacterial / drug effects; Imidazoles / chemical synthesis; Imidazoles / chemistry; Imidazoles / pharmacology; Microbial Sensitivity Tests
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Modulating the development of E. coli biofilms with 2-aminoimidazoles

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 20(21), 6310–6312.

By: C. Reed n, R. Huigens n, S. Rogers n & C. Melander n

author keywords: 2-Aminoimidazoles; E. coli; Biofilms
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / growth & development; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Drug Design; Escherichia coli / drug effects; Escherichia coli / growth & development; Hemolysis / drug effects; Humans; Imidazoles / chemical synthesis; Imidazoles / pharmacology; In Vitro Techniques; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Synergistic Effects between Conventional Antibiotics and 2-Aminoimidazole-Derived Antibiofilm Agents

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(5), 2112–2118.

By: S. Rogers n, R. Huigens n, J. Cavanagh n & C. Melander n

MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Biofilms / drug effects; Calcium Chloride / pharmacology; Chlorides / pharmacology; Colistin / pharmacology; Drug Resistance, Bacterial; Drug Resistance, Multiple; Drug Synergism; Enterococcus faecium / drug effects; Erythrocytes / drug effects; Escherichia coli / drug effects; Humans; Imidazoles / chemistry; Imidazoles / pharmacology; Magnesium / pharmacology; Manganese Compounds / pharmacology; Methicillin-Resistant Staphylococcus aureus / drug effects; Novobiocin / pharmacology; Staphylococcus epidermidis / drug effects; Tobramycin / pharmacology; Triazoles / pharmacology
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Synthesis and bacterial biofilm inhibition studies of ethyl N-(2-phenethyl) carbamate derivatives

Organic & Biomolecular Chemistry, 8(17), 3857–3859.

By: S. Rogers, D. Whitehead, T. Mullikin & C. Melander

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii

BIOORGANIC & MEDICINAL CHEMISTRY, 18(2), 663–674.

By: R. Huigens n, S. Reyes n, C. Reed n, C. Bunders n, S. Rogers n, A. Steinhauer n, C. Melander n

author keywords: 2-Aminobenzimidazole; Chemical library synthesis; Antibiotic; Multidrug-resistant bacteria; Staphylococcus aureus; Acinetobacter baumannii
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Benzimidazoles / chemical synthesis; Benzimidazoles / chemistry; Benzimidazoles / pharmacology; Drug Resistance, Multiple, Bacterial; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Molecular Conformation; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2009 journal article

A 2-Aminobenzimidazole That Inhibits and Disperses Gram-Positive Biofilms through a Zinc-Dependent Mechanism

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(29), 9868-+.

By: S. Rogers n, R. Huigens n & C. Melander n

MeSH headings : Benzimidazoles / chemical synthesis; Benzimidazoles / chemistry; Benzimidazoles / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Dose-Response Relationship, Drug; Gram-Positive Bacteria / drug effects; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship; Zinc / chemistry; Zinc / pharmacology
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Inhibition of Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation with a class of TAGE-triazole conjugates

ORGANIC & BIOMOLECULAR CHEMISTRY, 7(4), 794–802.

By: R. Huigens n, S. Rogers n, A. Steinhauer n & C. Melander n

MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / chemical synthesis; Biofilms / drug effects; Imidazoles / chemistry; Pseudomonas aeruginosa / drug effects; Small Molecule Libraries / chemical synthesis; Staphylococcus aureus / drug effects; Triazoles / chemical synthesis
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Tandem dispersion and killing of bacteria from a biofilm

ORGANIC & BIOMOLECULAR CHEMISTRY, 7(3), 603–606.

By: S. Rogers n, M. Krayer n, J. Lindsey n & C. Melander n

MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Bacteria / growth & development; Biofilms; Microbial Viability / drug effects; Photosensitizing Agents / chemistry; Photosensitizing Agents / pharmacology; Triazoles / chemistry; Triazoles / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018

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