@article{kim_kim_shin_choi_kwon_kim_kim_park_park_shin_2014, title={Application of response surface methodology to optimize the extraction of acetylcholinesterase inhibitors from Rhodiola sachalinensis}, volume={57}, number={6}, journal={Journal of the Korean Society for Applied Biological Chemistry}, author={Kim, C. R. and Kim, J. K. and Shin, E. C. and Choi, S. J. and Kwon, Y. K. and Kim, Y. J. and Kim, C. J. and Park, G. G. and Park, C. S. and Shin, D. H.}, year={2014}, pages={807–811} } @article{choi_kim_suh_kim_kim_kim_park_park_shin_2014, title={Ligularia fischeri Extract Protects Against Oxidative-Stress-Induced Neurotoxicity in Mice and PC12 Cells}, volume={17}, ISSN={["1557-7600"]}, DOI={10.1089/jmf.2013.3014}, abstractNote={Alzheimer's disease (AD) is pathologically characterized by the presence of amyloid plaques in brain and the overproduction of amyloid beta (Aβ), leading to learning and memory impairment and intense oxidative stress. In this study, the protective effect of Ligularia fischeri extract was investigated using PC12 cells. L. fischeri extract attenuated hydrogen-peroxide-induced DNA fragmentation in cells. In vivo behavioral tests were performed to examine the effects of the extract on amyloid-β peptide1-42-induced impairment of learning and memory in mice. A diet containing the extract increased alternation behaviors in the Y-maze test and step-through latency of passive avoidance task. Moreover, we found that consumption of the extract decreased lipid peroxidation in a biochemical study of brain tissue in mice. High-performance liquid chromatography was used to identify the active compounds in the extract. These results suggest that L. fischeri extract could be protective against Aβ-induced neurotoxicity, possibly due to the antioxidative capacity of its constituent, 3-O-caffeoylquinic acid.}, number={11}, journal={JOURNAL OF MEDICINAL FOOD}, author={Choi, Soo Jung and Kim, Jae Kyeom and Suh, Soo Hwan and Kim, Cho Rong and Kim, Hye Kyung and Kim, Chang-Ju and Park, Gwi Gun and Park, Cheung-Seog and Shin, Dong-Hoon}, year={2014}, month={Nov}, pages={1222–1231} } @article{suh_dwivedi_choi_jaykus_2014, title={Selection and characterization of DNA aptamers specific for Listeria species}, volume={459}, ISSN={["1096-0309"]}, DOI={10.1016/j.ab.2014.05.006}, abstractNote={Single-stranded (ss) DNA aptamers with binding affinity to Listeria spp. were selected using a whole-cell SELEX (Systematic Evolution of Ligands by EXponential enrichment) method. Listeria monocytogenes cells were grown at 37 °C and harvested at mid-log phase or early stationary phase to serve as the targets in SELEX. A total of 10 unique aptamer sequences were identified, six associated with log phase cells and four with stationary phase cells. Binding affinity of the aptamers was determined using flow cytometry and ranged from 10% to 44%. Four candidates having high binding affinity were further studied and found to show genus-specific binding affinity when screened against five different species within the Listeria genus. Using sequential binding assays combined with flow cytometry, it was determined that three of the aptamers (LM6-2, LM12-6, and LM12-13) bound to one apparent cell surface moiety, while a fourth aptamer (LM6-116) appeared to bind to a different cell surface region. This is the first study in which SELEX targeted bacterial cells at different growth phases. When used together, aptamers that bind to different cell surface moieties could increase the analytical sensitivity of future capture and detection assays.}, journal={ANALYTICAL BIOCHEMISTRY}, author={Suh, Soo Hwan and Dwivedi, Hari P. and Choi, Soo Jung and Jaykus, Lee-Ann}, year={2014}, month={Aug}, pages={39–45} } @article{choi_kim_kim_harris_kim_park_park_shin_2013, title={2,4-Di-tert-butylphenol from sweet potato protects against oxidative stress in PC12 cells and in mice}, volume={16}, number={11}, journal={Journal of Medicinal Food}, author={Choi, S. J. and Kim, J. K. and Kim, H. K. and Harris, K. and Kim, C. J. and Park, G. G. and Park, C. S. and Shin, D. H.}, year={2013}, pages={977–983} } @article{kim_shin_kim_park_choi_cho_shin_2013, title={Composition of fatty acids in commercially available tree nuts and their relationship with protective effects against oxidative stress-induced neurotoxicity}, volume={22}, number={4}, journal={Food Science and Biotechnology}, author={Kim, J. K. and Shin, E. C. and Kim, C. R. and Park, G. G. and Choi, S. J. and Cho, H. Y. and Shin, D. H.}, year={2013}, pages={1097–1104} } @article{kim_shin_kim_park_choi_park_shin_2013, title={Effects of Brussels sprouts and their phytochemical components on oxidative stress-induced neuronal damages in PC12 cells and ICR mice}, volume={16}, number={11}, journal={Journal of Medicinal Food}, author={Kim, J. K. and Shin, E. C. and Kim, C. R. and Park, G. G. and Choi, S. J. and Park, C. S. and Shin, D. H.}, year={2013}, pages={1057–1061} } @article{kim_choi_oh_kwon_lee_park_kim_heo_jun_park_et al._2013, title={Rubus coreanus Miquel inhibits acetylcholinesterase activity and prevents cognitive impairment in a mouse model of dementia}, volume={16}, number={9}, journal={Journal of Medicinal Food}, author={Kim, C. R. and Choi, S. J. and Oh, S. S. and Kwon, Y. K. and Lee, N. Y. and Park, G. G. and Kim, Y. J. and Heo, H. J. and Jun, W. J. and Park, C. S. and et al.}, year={2013}, pages={785–792} } @article{jeong_jo_jeong_jin_song_choi_shin_heo_2012, title={Antiamnesic effects of ethyl acetate fraction from chestnut (Castanea crenata var. dulcis) inner skin on A beta(25-35)-induced cognitive deficits in mice}, volume={15}, number={12}, journal={Journal of Medicinal Food}, author={Jeong, H. R. and Jo, Y. N. and Jeong, J. H. and Jin, D. E. and Song, B. G. and Choi, S. J. and Shin, D. H. and Heo, H. J.}, year={2012}, pages={1051–1056} } @article{kim_choi_bae_kim_cho_kim_lim_kim_kim_peterson_et al._2011, title={Effects of methoxsalen from poncirus trifoliata on acetylcholinesterase and trimethyltin-induced learning and memory impairment}, volume={75}, number={10}, journal={Bioscience Biotechnology and Biochemistry}, author={Kim, J. K. and Choi, S. J. and Bae, H. and Kim, C. R. and Cho, H. Y. and Kim, Y. J. and Lim, S. T. and Kim, C. J. and Kim, H. K. and Peterson, S. and et al.}, year={2011}, pages={1984–1989} }