Works (3)
Updated: July 5th, 2023 15:38
2017 journal article
Effects of perinatal bisphenol A exposure on the volume of sexually-dimorphic nuclei of juvenile rats: A CLARITY-SPA consortium study
NEUROTOXICOLOGY, 63, 33–42.
author keywords: Bisphenol A; Brain; Hypothalamus; Amygdala; Locus coeruleus; Sexually dimorphic
MeSH headings : Analysis of Variance; Animals; Animals, Newborn; Benzhydryl Compounds / toxicity; Brain / drug effects; Brain / pathology; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Estrogens / pharmacology; Ethinyl Estradiol / pharmacology; Female; Male; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Rats; Rats, Sprague-Dawley; Sex Characteristics
TL;DR:
The testing of the hypothesis that perinatal BPA exposure would induce morphological changes in hormone sensitive, sexually dimorphic brain regions suggest the developing brain is vulnerable to endocrine disruption by BPA at exposure levels below previous estimates by regulatory agencies.
(via Semantic Scholar)
www.ncbi.nlm.nih.gov (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Sex Specific Placental Accumulation and Behavioral Effects of Developmental Firemaster 550 Exposure in Wistar Rats
SCIENTIFIC REPORTS, 7.
MeSH headings : Age Factors; Analysis of Variance; Animals; Behavior, Animal / drug effects; Dose-Response Relationship, Drug; Female; Flame Retardants / adverse effects; Flame Retardants / analysis; Male; Molecular Structure; Placenta / drug effects; Placenta / metabolism; Pregnancy; Rats; Rats, Wistar; Sex Factors
TL;DR:
It is demonstrated that environmental chemicals may sex-dependently accumulate in the placenta, and that sex-biased exposure might translate to sex-specific adverse outcomes such as behavioral deficits.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study
Endocrinology, 157(10), 3856–3872.
Contributors: n, S. Belcher n , A. Planchart n , S. Turner * & H. Patisaul n
MeSH headings : Administration, Oral; Animals; Animals, Newborn; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / toxicity; Female; Gene Expression / drug effects; Hippocampus / drug effects; Hippocampus / metabolism; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Phenols / administration & dosage; Phenols / toxicity; Random Allocation; Rats; Rats, Sprague-Dawley; Sex Characteristics; Transcriptome / drug effects
TL;DR:
Preliminary data demonstrate prenatal BPA exposure, even at doses below the current no-observed-adverse-effect level, can alter gene expression in the developing brain.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
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