Sabrina E. Robertson

Works (2)

Updated: July 5th, 2023 15:38

2016 journal article

Recombinase-Dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types

CELL REPORTS, 15(11), 2563–2573.

By: N. Sciolino *, N. Plummer *, Y. Chen *, G. Alexander *, S. Robertson n, S. Dudek *, Z. McElligott *, P. Jensen *

MeSH headings : Alleles; Animals; Anxiety / complications; Anxiety / pathology; Anxiety / physiopathology; Behavior, Animal / drug effects; Clozapine; Dendrites / drug effects; Dendrites / metabolism; Designer Drugs / pharmacology; Gamma Rhythm / drug effects; Genetic Techniques; Hippocampus / drug effects; Hippocampus / pathology; Hippocampus / physiopathology; Humans; Hypothermia / complications; Hypothermia / pathology; Hypothermia / physiopathology; Integrases / metabolism; Locomotion / drug effects; Mice; Neuroglia / drug effects; Neuroglia / metabolism; Receptor, Muscarinic M3 / genetics; Recombination, Genetic / genetics
TL;DR: It is confirmed that activation of hM3Dq is sufficient to dose-dependently evoke phenotypic changes, without extreme phenotypes associated with hM2Dq overexpression, and offer the ability to non-invasively control activity of diverse cell types to uncover their function and dysfunction at any developmental stage. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Uncovering diversity in the development of central noradrenergic neurons and their efferents

BRAIN RESEARCH, 1641, 234–244.

By: S. Robertson n, N. Plummer * & P. Jensen *

author keywords: Norepinephrine; Hoxb1; Fate map; Recombinase-based intersectional; genetic fate mapping; Efferents; Rhombomere
MeSH headings : Adrenergic Neurons / cytology; Adrenergic Neurons / physiology; Animals; Brain / cytology; Brain / growth & development; Brain / physiology; Neural Pathways / cytology; Neural Pathways / growth & development; Neural Pathways / physiology
TL;DR: It is demonstrated that Hoxb1 expression is required by a subset of neurons in the pons with more restricted axonal targets than the full Hox b1-derived subpopulation, and the unique projection profile of this newly defined subpopulation suggests that it may be functionally distinct. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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