Sue Fenton

Precision environmental health: Establishing the role of environmental exposures in personalized medicine for oncology

Hamilton, A. M., Rickard, B. P., & Fenton, S. E. (2025, January). ENVIRONMENT INTERNATIONAL, Vol. 195.

Broadening the Environmental Lens to Include Social and Structural Determinants of Women’s Health Disparities

Environmental Health Perspectives, 132(1).

Whole mount preparation and analysis of rabbit mammary gland

REPRODUCTIVE TOXICOLOGY, 130.

A complex systems model of breast cancer etiology: The Paradigm II Model

PLOS ONE, 18(5), e0282878.

Erratum: Current Breast Milk PFAS Levels in the United States and Canada: After All This Time, Why Don’t We Know More?

Environmental Health Perspectives.

Exposure to select PFAS and PFAS mixtures alters response to platinum-based chemotherapy in endometrial cancer cell lines

Environmental Health, 22(1).

Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer

Cancers, 15(9), 2564.

Per- and Polyfluoroalkyl Substances and Breastfeeding as a Vulnerable Function: A Systematic Review of Epidemiological Studies

Toxics, 11(4), 325.

Per- and polyfluoroalkyl substances (PFAS) in breast milk and infant formula: A global issue

Environmental Research, 219, 115042.

A High-Throughput Toxicity Screen of 42 Per- and Polyfluoroalkyl Substances (PFAS) and Functional Assessment of Migration and Gene Expression in Human Placental Trophoblast Cells

Frontiers in Toxicology, 4.

Best practices to quantify the impact of reproductive toxicants on development, function, and diseases of the rodent mammary gland

Reproductive Toxicology, 112, 51–67.

Brominated flame retardants

Chemical Effects on Breast Development, Function, and Cancer Risk: Existing Knowledge and New Opportunities

Current Environmental Health Reports, 9(4), 535–562.

Current Breast Milk PFAS Levels in the United States and Canada: After All This Time, Why Don’t We Know More?

Environmental Health Perspectives, 130(2).

Editorial: Women in developmental and reproductive toxicology: 2021

Frontiers in Toxicology, 4.

Effective coordination, collaboration, communication, and partnering are needed to close the gaps for occupational PFAS exposure

American Journal of Industrial Medicine, 66(5), 351–352.

Invited Perspective: PFAS and Liver Disease: Bringing All the Evidence Together

Environmental Health Perspectives, 130(4).

Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease

Toxicology, 465, 153031.

Photochemical Targeting of Mitochondria to Overcome Chemoresistance in Ovarian Cancer<sup>†

Photochemistry and Photobiology, 99(2), 448–468.

Photodynamic Priming Overcomes Per‐ and Polyfluoroalkyl Substance (<scp>PFAS

Photochemistry and Photobiology, 99(2), 793–813.

Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines

International Journal of Molecular Sciences, 23(9), 5176.

TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice

Oncogene, 41(25), 3423–3432.

Transcriptional pathways linked to fetal and maternal hepatic dysfunction caused by gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) in CD-1 mice

Ecotoxicology and Environmental Safety, 248, 114314.

Breast Cancer and the Environment: Controversial and Emerging Exposures: a Virtual Workshop Summary

https://www.cancer.gov/research/areas/causes/breast-cancer-and-the-environment-controversial-and-emerging-exposures.pdf

Developmental Toxicology Collection

https://ehp.niehs.nih.gov/curated-collections/devtox

Environmental Factors Involved in Maternal Morbidity and Mortality

Journal of Women's Health, 30(2), 245–252.

Latent, sex-specific metabolic health effects in CD-1 mouse offspring exposed to PFOA or HFPO-DA (GenX) during gestation

Emerging Contaminants, 7, 219–235.

Looking for Proof in the Wrong Generation?

Cancer Epidemiology, Biomarkers & Prevention, 30(8), 1459–1461.

Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study

Toxicology, 461, 152900.

Yale School of Public Health Symposium: An overview of the challenges and opportunities associated with per- and polyfluoroalkyl substances (PFAS)

Science of The Total Environment, 778, 146192.

A Combined Morphometric and Statistical Approach to Assess Nonmonotonicity in the Developing Mammary Gland of Rats in the CLARITY-BPA Study

Environmental Health Perspectives, 128(5).

An assessment of serum‐dependent impacts on intracellular accumulation and genomic response of per‐ and polyfluoroalkyl substances in a placental trophoblast model

Environmental Toxicology, 35(12), 1395–1405.

CHDS: A national treasure that keeps on giving

Reproductive Toxicology, 92, 11–13.

Developmental Exposure to Tetrabromobisphenol A Has Minimal Impact on Male Rat Reproductive Health

Reproductive Toxicology, 95, 59–65.

Early life exposure to per- and polyfluoroalkyl substances (PFAS) and latent health outcomes: A review including the placenta as a target tissue and possible driver of peri- and postnatal effects

Toxicology, 443, 152565.

Estimating Environmental Hazard and Risks from Exposure to Per‐ and Polyfluoroalkyl Substances (PFASs): Outcome of a SETAC Focused Topic Meeting

Environmental Toxicology and Chemistry, 40(3), 543–549.

Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)

Environmental Health Perspectives, 128(2).

Inflammatory Biomarkers and Breast Cancer Risk: A Systematic Review of the Evidence and Future Potential for Intervention Research

International Journal of Environmental Research and Public Health, 17(15), 5445.

Investigation of the adolescent female breast transcriptome and the impact of obesity

Breast Cancer Research, 22(1).

Per‐ and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

Environmental Toxicology and Chemistry, 40(3), 606–630.

Reconstructing the Composition of Per- and Polyfluoroalkyl Substances in Contemporary Aqueous Film-Forming Foams

Environmental Science & Technology Letters, 8(1), 59–65.

Environmental Chemicals in Breast Milk

Estimating risk of neurotoxicity from early life exposure: Human milk is an appropriate matrix, but messages should not discourage breastfeeding

Science of The Total Environment, 693, 133665.

PFAS 2019 Collection

https://ehp.niehs.nih.gov/curated-collections/PFAS

Sex-specific behavioral effects following developmental exposure to tetrabromobisphenol A (TBBPA) in Wistar rats

NeuroToxicology, 75, 136–147.

Animal models of endocrine disruption

Best Practice & Research Clinical Endocrinology & Metabolism, 32(3), 283–297.

Associations between longitudinal serum perfluoroalkyl substance (PFAS) levels and measures of thyroid hormone, kidney function, and body mass index in the Fernald Community Cohort

Environmental Pollution, 242, 894–904.

Evaluation of Prenatal Exposure to Bisphenol Analogues on Development and Long-Term Health of the Mammary Gland in Female Mice

Environmental Health Perspectives, 126(8).

Tetrabromobisphenol-A Promotes Early Adipogenesis and Lipogenesis in 3T3-L1 Cells

Toxicological Sciences, 166(2), 332–344.

The Mammary Gland

The Mammary Gland: An Overview

Brominated Flame Retardants

Effects of perfluorinated chemicals on thyroid function, markers of ovarian reserve, and natural fertility

Reproductive Toxicology, 69, 53–59.

Gestational exposure to perfluorooctanoic acid (PFOA): Alterations in motor related behaviors

NeuroToxicology, 58, 110–119.

Polybrominated Diphenyl Ethers in Human Milk and Serum from the U.S. EPA MAMA Study: Modeled Predictions of Infant Exposure and Considerations for Risk Assessment

Environmental Health Perspectives, 125(4), 706–713.

Quantifying Branching Density in Rat Mammary Gland Whole-mounts Using the Sholl Analysis Method

Journal of Visualized Experiments, 7(125).

Sectioning Mammary Gland Whole Mounts for Lesion Identification

Journal of Visualized Experiments, 7(125).

Differences in the Rate of in Situ Mammary Gland Development and Other Developmental Endpoints in Three Strains of Female Rat Commonly Used in Mammary Carcinogenesis Studies

Toxicologic Pathology, 44(7), 1021–1033.

Mammary Gland Evaluation in Juvenile Toxicity Studies

Toxicologic Pathology, 44(7), 1034–1058.

Preparation of High-quality Hematoxylin and Eosin–stained Sections from Rodent Mammary Gland Whole Mounts for Histopathologic Review

Toxicologic Pathology, 44(7), 1059–1064.

A special issue dedicated to a complex tissue

Reproductive Toxicology, 54, 1–5.

Application of Sholl analysis to quantify changes in growth and development in rat mammary gland whole mounts

Reproductive Toxicology, 54, 129–135.

Concentrations of environmental phenols and parabens in milk, urine and serum of lactating North Carolina women

Reproductive Toxicology, 54, 120–128.

EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

Endocrine Reviews, 36(6), E1–E150.

Effects of PFOA on Endocrine-Related Systems

Essential role of Orai1 store-operated calcium channels in lactation

Proceedings of the National Academy of Sciences, 112(18), 5827–5832.

Executive Summary to EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

Endocrine Reviews, 36(6), 593–602.

Screening for Chemical Contributions to Breast Cancer Risk: A Case Study for Chemical Safety Evaluation

Environmental Health Perspectives, 123(12), 1255–1264.

The mammary gland is a sensitive pubertal target in CD-1 and C57Bl/6 mice following perinatal perfluorooctanoic acid (PFOA) exposure

Reproductive Toxicology, 54, 26–36.

Timing of Environmental Exposures as a Critical Element in Breast Cancer Risk

The Journal of Clinical Endocrinology & Metabolism, 100(9), 3245–3250.

Hepatic Mitochondrial Alteration in CD-1 Mice Associated with Prenatal Exposures to Low Doses of Perfluorooctanoic Acid (PFOA)

Toxicologic Pathology, 43(4), 546–557.

Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk

Critical Reviews in Toxicology, 44(7), 600–617.

Perfluorooctanoic Acid (PFOA)–induced Liver Lesions in Two Strains of Mice Following Developmental Exposures

Toxicologic Pathology, 43(4), 558–568.

Risk factors as biomarkers of susceptibility in breast cancer

Breast Cancer and the Environment: Prioritizing Prevention

http://www.niehs.nih.gov/about/assets/docs/ibcercc_full_508.pdf.

Endocrine Disruptors and the Breast: Early Life Effects and Later Life Disease

Journal of Mammary Gland Biology and Neoplasia, 18(1), 43–61.

Exposure to diethylstilbestrol during sensitive life stages: A legacy of heritable health effects

Birth Defects Research Part C: Embryo Today: Reviews, 99(2), 134–146.

Mammary Gland

CHAPTER 11. Breast Cancer – Importance of Life Stage with Respect to Environmental Influences

In Issues in Toxicology (pp. 293–330).

Histopathologic changes in the uterus, cervix and vagina of immature CD-1 mice exposed to low doses of perfluorooctanoic acid (PFOA) in a uterotrophic assay

Reproductive Toxicology, 33(4), 506–512.

Perinatal Environmental Exposures Affect Mammary Development, Function, and Cancer Risk in Adulthood

Annual Review of Pharmacology and Toxicology, 52(1), 455–479.

Researching chemicals in human milk can be conducted without discouraging breastfeeding

Bosnian Journal of Basic Medical Sciences, 12(2), 137.

Adverse Health Outcomes Caused By Dioxin‐Activated AHR in Humans

Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA‐induced mammary tumors

International Journal of Cancer, 128(7), 1509–1523.

Atrazine: An Environmental Endocrine Disruptor That Alters Mammary Gland Development and Tumor Susceptibility

Brominated flame retardants

In Reproductive and Developmental Toxicology (pp. 523–541).

Developmental Exposure to Environmental Endocrine Disruptors and Adverse Effects on Mammary Gland Development

Developmental toxicology—new directions workshop: refining testing strategies and study designs

Birth Defects Research Part B: Developmental and Reproductive Toxicology, 92(5), 404–412.

Early influences on mammary gland development, with Suzanne Fenton. Interview by Ashley Ahearn

Environmental Health Perspectives, 119(10), 1.

Endocrine disrupting properties of perfluorooctanoic acid

The Journal of Steroid Biochemistry and Molecular Biology, 127(1-2), 16–26.

Environmental Chemicals in Breast Milk

Environmental Exposures and Mammary Gland Development: State of the Science, Public Health Implications, and Research Recommendations

Environmental Health Perspectives, 119(8), 1053–1061.

Evidence for Endocrine Disruption in Children: Sensitive Developmental Endpoints

In Encyclopedia of Environmental Health (pp. 615–623).

Gestational and Chronic Low-Dose PFOA Exposures and Mammary Gland Growth and Differentiation in Three Generations of CD-1 Mice

Environmental Health Perspectives, 119(8), 1070–1076.

Mammary Gland as a Sensitive Tissue to Developmental Exposures of Perfluorooctanoic Acid (PFOA) in the Mouse

Prenatal Perfluorooctanoic Acid Exposure in CD-1 Mice: Low-Dose Developmental Effects and Internal Dosimetry

Toxicological Sciences, 122(1), 134–145.

Developmental Exposure to a Commercial PBDE Mixture, DE-71: Neurobehavioral, Hormonal, and Reproductive Effects

Toxicological Sciences, 116(1), 297–312.

Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats

Reproductive Toxicology, 30(4), 540–549.