Shobhan Gaddameedhi

A new role of TRPM8 in circadian rhythm and molecular clock

Mishra, S. K., & Gaddameedhi, S. (2023, January 20). ACTA PHYSIOLOGICA, Vol. 1.

CIRCADIAN DYSREGULATION OF HUMAN DNA REPAIR GENES AND ELEVATED DNA DAMAGE IN SIMULATED NIGHT SHIFT SCHEDULE

Sleep. https://publons.com/wos-op/publon/54906417/

Circadian disruption and cisplatin chronotherapy for mammary carcinoma

TOXICOLOGY AND APPLIED PHARMACOLOGY, 436.

Circadian effects on UV-induced damage and mutations

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 789.

Endogenous Diurnal Patterns of Adrenal and Gonadal Hormones During a 24-Hour Constant Routine After Simulated Shift Work

JOURNAL OF THE ENDOCRINE SOCIETY, 6(12).

Let's talk about sex: A biological variable in immune response against melanoma

Dakup, P. P., Greer, A. J., & Gaddameedhi, S. (2022, February 3). PIGMENT CELL & MELANOMA RESEARCH, Vol. 35.

Simulated Night- Shift Schedule Disrupts the Plasma Lipidome and Reveals Early Markers of Cardiovascular Disease Risk

NATURE AND SCIENCE OF SLEEP, 14, 981–994.

Working around the Clock: Is a Person's Endogenous Circadian Timing for Optimal Neurobehavioral Functioning Inherently Task-Dependent?

CLOCKS & SLEEP, 4(1), 23–36.

Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells

Sarkar, S., Porter, K. I., Dakup, P. P., Gajula, R. P., Koritala, B. S. C., Hylton, R., … Gaddameedhi, S. (2021, July 6). PIGMENT CELL & MELANOMA RESEARCH, Vol. 34.

Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia

NATURE COMMUNICATIONS, 12(1).

Night shift schedule alters endogenous regulation of circulating cytokines

Neurobiology of Sleep and Circadian Rhythms, 10, 100063.

Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans

JOURNAL OF PINEAL RESEARCH, 70(3).

Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(26).

Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(17).

Sex differences in the association between tumor growth and T cell response in a melanoma mouse model

Cancer Immunology, Immunotherapy, 69(10), 2157–2162.

Solar ultraviolet-induced DNA damage response: Melanocytes story in transformation to environmental melanomagenesis.

Environmental and Molecular Mutagenesis.

The circadian clock protects against acute radiation-induced dermatitis

Toxicology and Applied Pharmacology, 399, 115040.

The circadian clock protects against ionizing radiation-induced cardiotoxicity.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology.

Cardiac autonomic activity during simulated shift work

Industrial Health.

It's About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes

Yale Journal of Biology and Medicine. https://publons.com/wos-op/publon/32413204/

It's About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes.

The Yale Journal of Biology and Medicine. https://europepmc.org/articles/PMC6585512

Circadian clock protects against radiation-induced dermatitis and cardiomyopathy in mice

Cancer Research.

Circulating Plasma Exosomes May Signal Circadian Clock Misalignment to Peripheral Tissues

American Journal of Respiratory and Critical Care Medicine. https://publons.com/wos-op/publon/35726971/

Separation of circadian- and behavior-driven metabolite rhythms in humans provides a window on peripheral oscillators and metabolism

Proceedings of the National Academy of Sciences, 115(30), 7825–7830.

The circadian clock regulates cisplatin-induced toxicity and tumor regression in melanoma mouse and human models.

Oncotarget.

UV-B-Induced Erythema in Human Skin: The Circadian Clock Is Ticking.

The Journal of Investigative Dermatology.

Chronopharmacology of cisplatin: role of the circadian rhythm in modulating cisplatin-induced toxicity in melanoma mouse model

Cancer Research.

Impact of the Circadian Clock on UV-Induced DNA Damage Response and Photocarcinogenesis

Photochemistry & Photobiology.

Shift Work: Disrupted Circadian Rhythms and Sleep-Implications for Health and Well-Being.

Current Sleep Medicine Reports.

Chronopharmacology of cisplatin: Role of the circadian rhythm in modulating the cisplatin transporters levels

The FASEB Journal. https://publons.com/wos-op/publon/32413213/

Circadian Clock, Cancer, and Chemotherapy

Biochemistry.

Commentary: Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.

Frontiers in Physiology.

Development and validation of a new transgenic hairless albino mouse as a mutational model for potential assessment of photocarcinogenicity.

Mutation Research. Genetic Toxicology and Environmental Mutagenesis.

Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity.

Cancers.

The Circadian Clock Controls Sunburn Apoptosis and Erythema in Mouse Skin

Journal of Investigative Dermatology.

DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair.

The Journal of Biological Chemistry.

Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock.

Genes & Development.

Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells

Nucleic Acids Research.

DNA Damage-Specific Control of Cell Death by Cryptochrome in p53-Mutant Ras-Transformed Cells

Cancer Research.

Nucleotide excision repair in human cells: fate of the excised oligonucleotide carrying DNA damage in vivo.

The Journal of Biological Chemistry.

Effect of circadian clock mutations on DNA damage response in mammalian cells.

Cell Cycle (Georgetown, Tex.).

Control of skin cancer by the circadian rhythm

Proceedings of the National Academy of Sciences, 108(46), 18790–18795.

Melanoma and DNA damage from a distance (farstander effect).

Pigment Cell & Melanoma Research.

Similar nucleotide excision repair capacity in melanocytes and melanoma cells.

Cancer Research.

Association between the unfolded protein response, induced by 2-deoxyglucose, and hypersensitivity to cisplatin: a mechanistic study employing molecular genomics.

Journal of Cancer Research and Therapeutics.

Loss of cryptochrome reduces cancer risk in p53 mutant mice.

Proceedings of the National Academy of Sciences of the United States of America.

Deciphering the association between up-regulation of glucose regulated protein of Mr-78 kDa (GRP78) and hypersensitivity to cisplatin employing comparative genomics

The FASEB Journal. https://publons.com/wos-op/publon/54906423/

Up-regulation of glucose regulated protein of M-r-78KDa (GRP78) followed by cisplatin treatment leads to mitochondrial mediated apoptosis through caspase-2 activation

Cancer Research. https://publons.com/wos-op/publon/54906422/

In-gel precipitation of enzymatically released phosphate.

Analytical Biochemistry.