Sam Harp

College of Sciences

Works (2)

Updated: July 5th, 2023 14:34

2021 journal article

Fentanyl-induced acute and conditioned behaviors in two inbred mouse lines: Potential role for Glyoxalase

PHYSIOLOGY & BEHAVIOR, 243.

By: S. Harp n, M. Martini n, W. Rosenow *, L. Mesner*, H. Johnson n, C. Farber *, E. Rissman n

author keywords: RNA-sequencing; Opioids; Metabolism; Fentanyl; Conditioned place preference; Acute activity; Conditioned activity
MeSH headings : Animals; COVID-19; Fentanyl / pharmacology; Humans; Mice; Mice, Inbred C57BL; Pandemics; SARS-CoV-2
TL;DR: Interestingly, few differentially expressed genes were noted using treatment as the main factor, however many genes differed between strains, and it is suggested that future studies assess the ability of Glo1 and related metabolites to modify opioid intake. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 29, 2021

2020 review

Sexual Differentiation and Substance Use: A Mini-Review

[Review of ]. ENDOCRINOLOGY, 161(9).

By: S. Harp n, M. Martini n, W. Lynch * & E. Rissman n

author keywords: cocaine; sexual differentiation; mice; sex chromosomes; dopamine; estrogen
MeSH headings : Aging / drug effects; Aging / physiology; Animals; Brain / drug effects; Brain / physiology; Gonadal Steroid Hormones / pharmacology; Humans; Reward; Risk Factors; Sex Characteristics; Sex Differentiation / physiology; Sex Factors; Substance-Related Disorders / epidemiology; Substance-Related Disorders / etiology
TL;DR: It is proposed that sex chromosome complement also plays a role in determining sex-specific drug-taking behavior and the four core genotypes mouse model is proposed as an effective tool for answering these questions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: September 28, 2020

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