@article{walsh_gardner_deiters_williams_2014, title={Intracellular Light-Activation of Riboswitch Activity}, volume={15}, ISSN={1439-4227}, url={http://dx.doi.org/10.1002/cbic.201400024}, DOI={10.1002/cbic.201400024}, abstractNote={Abstract By combining a riboswitch with a cell‐permeable photocaged small‐molecule ligand, an optochemical gene control element was constructed that enabled spatial and temporal control of gene expression in bacterial cells. The simplicity of this strategy, coupled with the ability to create synthetic riboswitches with tailored ligand specificities and output in a variety of microorganisms, plants, and fungi might afford a general strategy to photocontrol gene expression in vivo. The ability to activate riboswitches by using light enables the interrogation and manipulation of a wide range of biological processes with high precision, and will have broad utility in the regulation of artificial genetic circuits.}, number={9}, journal={ChemBioChem}, publisher={Wiley}, author={Walsh, Steven and Gardner, Laura and Deiters, Alexander and Williams, Gavin J.}, year={2014}, month={May}, pages={1346–1351} } @article{miller_walsh_hollar_rideout_pittman_2011, title={Engineering and Innovation: An Immersive Start-up Experience}, volume={44}, ISSN={["1558-0814"]}, DOI={10.1109/mc.2011.33}, abstractNote={Since 1993, the Engineering Entrepreneurs Program has been helping engineering students become entrepreneurs. What began as informal student meetings has grown to a three-course sequence with graduates who have pioneered successful companies. Assessments show a positive correlation between program participation and entrepreneurial action.}, number={4}, journal={COMPUTER}, author={Miller, Thomas K., III and Walsh, Stephen J. and Hollar, Seth and Rideout, Elaine C. and Pittman, Beryl C.}, year={2011}, month={Apr}, pages={38–46} } @article{miller_gittard_edwards_lopez_xiao_wheeler_monteiro-riviere_brozik_polsky_narayan_2011, title={Integrated carbon fiber electrodes within hollow polymer microneedles for transdermal electrochemical sensing}, volume={5}, ISSN={1932-1058}, url={http://dx.doi.org/10.1063/1.3569945}, DOI={10.1063/1.3569945}, abstractNote={In this study, carbon fiber electrodes were incorporated within a hollow microneedle array, which was fabricated using a digital micromirror device-based stereolithography instrument. Cell proliferation on the acrylate-based polymer used in microneedle fabrication was examined with human dermal fibroblasts and neonatal human epidermal keratinocytes. Studies involving full-thickness cadaveric porcine skin and trypan blue dye demonstrated that the hollow microneedles remained intact after puncturing the outermost layer of cadaveric porcine skin. The carbon fibers underwent chemical modification in order to enable detection of hydrogen peroxide and ascorbic acid; electrochemical measurements were demonstrated using integrated electrode-hollow microneedle devices.}, number={1}, journal={Biomicrofluidics}, publisher={AIP Publishing}, author={Miller, Philip R. and Gittard, Shaun D. and Edwards, Thayne L. and Lopez, DeAnna M. and Xiao, Xiaoyin and Wheeler, David R. and Monteiro-Riviere, Nancy A. and Brozik, Susan M. and Polsky, Ronen and Narayan, Roger J.}, year={2011}, month={Mar}, pages={013415} } @book{miller_walsh_2010, title={The Prepared Mind: Engineering Entrepreneurs Program at NC State}, publisher={NCSU Engineering Entrepreneurs Program}, author={Miller, T. K. and Walsh, S.J}, year={2010} }