Samuel James Widmayer

Works (3)

Updated: July 15th, 2023 21:15

2020 journal article

Age and Genetic Background Modify Hybrid Male Sterility in House Mice

GENETICS, 216(2), 585–597.

By: S. Widmayer n, M. Handel * & D. Aylor n

author keywords: hybrid male sterility; aging; genetic background; spermatogenesis; mouse
MeSH headings : Aging / genetics; Aging / physiology; Animals; Female; Genetic Background; Genetic Loci; Hybridization, Genetic; Infertility, Male / genetics; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Multifactorial Inheritance
TL;DR: Results point to multiple segregating HMS modifier alleles, some of which have age-related modes of action, which will advance understanding both of the genetic architecture of HMS and of how reproductive barriers are maintained between house mouse subspecies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: November 2, 2020

2019 article

Meeting report: 32nd international mammalian genome conference Abstracts

Moskowitz, J., Tracey, L., Widmayer, S., & Dumont, B. (2019, April). MAMMALIAN GENOME, Vol. 30, pp. 43–53.

By: J. Moskowitz*, L. Tracey*, S. Widmayer n & B. Dumont*

MeSH headings : Animals; Computational Biology; Genome; Genomics; Humans; Mammals / genetics
TL;DR: An overview of the meeting’s proceedings is provided and the exciting, novel research findings communicated by conference participants that, collectively, are advancing the frontiers of mammalian genetics and genomics are summarized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 20, 2019

2019 journal article

Novel Neuroprotective Loci Modulating Ischemic Stroke Volume in Wild-Derived Inbred Mouse Strains

GENETICS, 213(3), 1079–1092.

By: H. Lee *, S. Widmayer n, M. Huang*, D. Aylor n & D. Marchuk *

author keywords: ischemic stroke; wild-derived mouse strains; neuroprotection; quantitative trait mapping
MeSH headings : Animals; Female; Genetic Predisposition to Disease; Inbreeding; Infarction, Middle Cerebral Artery / genetics; Male; Mice; Polymorphism, Single Nucleotide; Quantitative Trait Loci
TL;DR: This study expanded the pool of allelic variation among classical inbred mouse strains by utilizing the eight founder strains of the Collaborative Cross and found a wild-derived strain, WSB/EiJ, that breaks this general rule that collateral vessel density inversely correlates with infarct volume. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 25, 2019

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