Sachin Kadian
Biomedical Engineering, Material science, Flexible electronic and biomedical devices, Nanoelectronics
Dr. Sachin Kadian is a Postdoctoral Research Scholar in the Joint Department of Biomedical Engineering at the University of North Carolina and North Carolina State University, NC, USA. Prior to this, he was a Postdoctoral Research Assistant at the School of Materials Engineering, Purdue University, USA, and DST, SERB-Overseas Visiting Doctoral Fellow (OVDF) at the Department of Electrical & Computer Engineering, University of Alberta (UofA), Edmonton, Canada supported by Govt. of India & UofA. He earned his Ph.D. degree with major in materials science and biomedical engineering from the Department of Polymer and Process Engineering, Indian Institute of Technology Roorkee, India in 2021. He received his M. Tech. in Biomedical Engineering from the National Institute of Technology (NIT), Kurukshetra in 2016 and B. Tech. in Electronics and Communication Engineering from the University Institute of Engineering and Technology (UIET), Kurukshetra, India in 2014. He has co-authored over ~35 publications in reputed SCI journals and international conferences as well as book chapters. Based on his Ph.D. research work, he has received 10 awards and recognitions such as outstanding research article, article featured in top 50 most popular articles, best paper award, top-cited article of the journals, three-minute Thesis (3-MT) award, SERB-OVDF etc. His co-authored work has also been highlighted in Nature India as “Glowing biosensor to detect an aggressive lung cancer”. His current research interests include the synthesis and characterization of quantum dots (graphene, sulfur, carbon, perovskites, and zinc oxide), nanomaterials, nanocomposites and their applications in biosensors, energy storage, photovoltaics, chemo-sensors, bioimaging and antibacterial agents.
Works (35)
Updated: November 1st, 2024 05:05
2024 article
Additive manufacturing of microneedles for sensing and drug delivery
Bedir, T., Kadian, S., Shukla, S., Gunduz, O., & Narayan, R. (2024, July 28). EXPERT OPINION ON DRUG DELIVERY, Vol. 7.
author keywords: 3D printing; additive manufacturing; biosensing; microneedles; transdermal drug delivery
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 5, 2024
2024 journal article
Machine learning enabled microneedle-based colorimetric pH sensing patch for wound health monitoring and meat spoilage detection
MICROCHEMICAL JOURNAL, 200.
author keywords: Microneedle; Colorimetric; Biosensor; Wound; Machine learning monitoring; Food monitoring
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 22, 2024
2024 journal article
Minimally invasive detection of buprenorphine using a carbon-coated 3D-printed microneedle array
MICROCHIMICA ACTA, 191(11).
author keywords: Conducting microneedles; 3D printing; Machine learning; Electrochemical sensor; Buprenorphine; Interstitial fluid; Carbon coating
Sources: Web Of Science, NC State University Libraries
Added: October 28, 2024
2023 review
Computational approaches to delivery of anticancer drugs with multidimensional nanomaterials
[Review of ]. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 21, 4149–4158.
author keywords: Nanotubes; Graphene oxide; Molecular dynamics; Molecular mechanics; Force fields; Drug delivery
TL;DR:
Advances in simulation techniques are summarized, which are extremely valuable in initial geometry optimization and evaluation of the loading and unloading behavior of encapsulated drug molecules.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2023
2023 article
Electrochemical detection of cholesterol in human biofluid using microneedle sensor
Li, Z., Kadian, S., Mishra, R. K. K., Huang, T., Zhou, C., Liu, S., … Zhu, Z. (2023, May 22). JOURNAL OF MATERIALS CHEMISTRY B, Vol. 5.
TL;DR:
The developed microneedle sensor showed satisfactory stability and good selectivity towards cholesterol in the presence of potential interfering biomolecules, including glucose, lactic acid, uric Acid, and ascorbic acid, and this sensor exhibits enormous promise for straightforward, sensitive, and minimally invasive monitoring of cholesterol.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 19, 2023
2023 journal article
Graphene nanocomposites for real-time electrochemical sensing of nitric oxide in biological systems
Applied Physics Reviews.
TL;DR:
The building blocks of these graphene-based electrochemical sensors, including the conjugation of different electrolytic materials and biomolecules on graphene, and sensing mechanisms, are examined, by reflecting on the recent developments in materials and engineering for real-time detection of NO in biological systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: January 28, 2024
2023 journal article
Machine learning enabled onsite electrochemical detection of lidocaine using a microneedle array integrated screen printed electrode
ELECTROCHIMICA ACTA, 475.
Contributors: n , S. Sahoo n , P. Kumari * & R. Narayan n
author keywords: Graphene; Screen printing; Microneedle; Lidocaine; Biosensing
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 28, 2024
2023 personal communication
Novel hollow biodegradable microneedle for amphotericin B delivery
Machekposhti, S. A., Kadian, S., Vanderwal, L., Stafslien, S., & Narayan, R. J. (2023, August).
TL;DR:
The previous study aimed to deliver amphotericin B by biodegradable solid microneedles by mixing it with Gantrez R © AN 119 BF and leaving it left at room temperature for approximately 2 weeks to be solidified in the shape ofmicroneedle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 31, 2023
2023 journal article
Probe sonication-assisted rapid synthesis of highly fluorescent sulfur quantum dots
NANOTECHNOLOGY, 34(30).
Contributors: n , N. Chaulagain *, N. Joshi n , K. Alam *, K. Cui *, K. Shankar *, G. Manik *, R. Narayan n
author keywords: sulfur quantum dots; probe sonication; fluorescent nanomaterials; photostability; quantum yield
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 30, 2023
2023 review
Probes for noninvasive biological visualization and biosensing of cancer cells
[Review of ]. APPLIED PHYSICS REVIEWS, 10(4).
TL;DR:
This critical review presents an overview of bioimaging probes, including functionalized chromophoric systems, non-functionalized chromophile systems, and nanoscale biosensors, and technical challenges and future directions related to these approaches are considered.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 11, 2023
2023 journal article
Recent advancements in machine learning enabled portable and wearable biosensors
TALANTA OPEN, 8.
author keywords: Machine learning; Clinical decision making; Portable and wearable biosensors
Sources: Web Of Science, NC State University Libraries
Added: December 18, 2023
2023 journal article
Smart Capsule for Targeted Detection of Inflammation Levels Inside the GI Tract
IEEE Transactions on Biomedical Engineering.
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: May 1, 2024
2022 journal article
A Biodegradable Hybrid Micro/Nano Conductive Zinc Paste for Paper-Based Flexible Bioelectronics
Advanced Materials Technologies.
Contributors: A. Zareei *, V. Selvamani *, S. Gopalakrishnan *, * , M. Maruthamuthu *, Z. He *, J. Nguyen *, H. Wang *, R. Rahimi *
Source: ORCID
Added: September 12, 2023
2022 journal article
A Review of Recent Progress in Molecular Dynamics and Coarse-Grain Simulations Assisted Understanding of Wettability
Archives of Computational Methods in Engineering, 29(5), 3059–3085.
Contributors: S. Sethi *, * & G. Manik *
Source: ORCID
Added: September 12, 2023
2022 journal article
A wireless chipless printed sensor tag for real-time radiation sterilization monitoring
Journal of Materials Chemistry C.
Contributors: U. Heredia-Rivera*, S. Gopalakrishnan *, * , S. Nejati *, V. Kasi * & R. Rahimi *
TL;DR:
The development of an advanced dosimeter for monitoring the gamma radiation dosage during the sterilization process is being developed.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2022 chapter
Graphene Based Hybrid Nanocomposites for Solar Cells
In Current and Future Developments in Nanomaterials and Carbon Nanotubes (pp. 61–77).
Source: ORCID
Added: September 12, 2023
2022 journal article
Highly sensitive and selective detection of dopamine with boron and sulfur co-doped graphene quantum dots
Scientific Reports, 12(1).
Contributors: M. Chatterjee*, P. Nath *, * , A. Kumar *, V. Kumar *, P. Roy *, G. Manik *, S. Satapathi *
Source: ORCID
Added: September 12, 2023
2022 journal article
Laser-Assisted Nanotexturing and Silver Immobilization on Titanium Implant Surfaces to Enhance Bone Cell Mineralization and Antimicrobial Properties
Langmuir, 38(13), 4014–4027.
Contributors: V. Selvamani *, * , D. Detwiler*, A. Zareei *, I. Woodhouse *, Z. Qi *, S. Peana *, A. Alcaraz*, H. Wang *, R. Rahimi *
TL;DR:
A facile two-step laser nanotexturing and immobilization of silver onto the titanium implants to improve both cellular integration and antibacterial properties of Ti surfaces and qualifies this approach as a promising candidate for novel rapid surface modification of biomedical metal implants.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2022 journal article
Printed Low-Cost PEDOT:PSS/PVA Polymer Composite for Radiation Sterilization Monitoring
ACS Sensors, 7(4), 960–971.
Contributors: U. Heredia Rivera*, * , S. Nejati *, J. White *, S. Sedaghat *, Z. Mutlu *, R. Rahimi *
TL;DR:
The development of an all-printed disposable low-cost sensor that exploits the change in electrical impedance of a semi-interpenetrating polymer network (SIPN) composed of poly(vinyl alcohol) (PVA) and poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) as a functional polymer composite for radiation sterilization monitoring applications is demonstrated.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2022 journal article
Printed graphene-based electrochemical sensor with integrated paper microfluidics for rapid lidocaine detection in blood
Analytica Chimica Acta, 1229, 340332.
TL;DR:
A disposable point-of-care (POC) diagnostic platform composed of an integrated graphene-based electrochemical sensor with paper-based microfluidics for rapid detection of lidocaine levels in serum and blood samples that could help in better pain management and reduce potential side effects or misuse of analgesics.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2022 journal article
Synergistic Enhancement of the Photoelectrochemical Performance of TiO<sub>2</sub>Nanorod Arrays through Embedded Plasmon and Surface Carbon Nitride Co-sensitization
ACS Applied Materials and Interfaces, 14(21), 24309–24320.
Contributors: N. Chaulagain *, K. Alam *, * , N. Kumar *, J. Garcia *, G. Manik *, K. Shankar *
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: September 12, 2023
2021 conference paper
An Ultrasensitive Fluorescent Paper Based Acidic Gas Sensing Platform
Proceedings of IEEE Sensors, 2021-October.
Contributors: * , N. Chaulagain *, H. Rajashekhar *, D. Vrushabendrakumar*, G. Manik * & K. Shankar *
Source: ORCID
Added: September 12, 2023
2021 journal article
Effect of sulfur-doped graphene quantum dots incorporation on morphological, optical and electron transport properties of CH3NH3PbBr3 perovskite thin films
Journal of Materials Science: Materials in Electronics, 6(13), 17406–17417.
Contributors: * , N. Tailor *, N. Chaulagain *, K. Shankar *, S. Satapathi * & G. Manik *
Source: ORCID
Added: September 12, 2023
2021 journal article
Recent advances in graphene quantum dot-based optical and electrochemical (bio)analytical sensors
Materials Advances, 2(17), 5513–5541.
Contributors: A. Kalkal *, * , R. Pradhan *, G. Manik * & G. Packirisamy
Source: ORCID
Added: September 12, 2023
2021 journal article
Ti3C2-MXene decorated with nanostructured silver as a dual-energy acceptor for the fluorometric neuron specific enolase detection
Biosensors and Bioelectronics, 195.
Contributors: A. Kalkal *, * , S. Kumar *, G. Manik *, P. Sen *, S. Kumar*, G. Packirisamy
TL;DR:
A fluorescent turn-on biosensing system is constructed that revealed improved biosensing characteristics compared to Ti3C2-MXene, graphene and AuNPs for the detection of neuron-specific enolase (NSE), including higher sensitivity, broader linear detection range, and faster response time.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: September 12, 2023
2021 journal article
Tunable ionic conductivity and photoluminescence in quasi-2D CH<sub>3</sub>NH<sub>3</sub>PbBr<sub>3</sub>thin films incorporating sulphur doped graphene quantum dots
Physical Chemistry Chemical Physics, 23(39), 22733–22742.
Contributors: R. Kumar *, J. Kumar *, * , P. Srivastava *, G. Manik * & M. Bag *
TL;DR:
This investigation has synthesized a mixture of 2D/3D perovskites by incorporating sulphur-doped graphene quantum dots (SGQDs) and demonstrated that the optical and electrical properties of the hybrid system can be tuned by controlling the ion conductivity through the active layer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: September 12, 2023
2020 journal article
A highly sensitive and selective detection of picric acid using fluorescent sulfur-doped graphene quantum dots
Luminescence.
Contributors: * & G. Manik *
TL;DR:
Analytical performance of the assay in terms of its detection limit, linearity range, and recovery exhibited reasonable superiority over previously reported methods, thereby holding enormous promise as a simple, sensitive, and selective method for detection of PA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: September 12, 2023
2020 journal article
Biofunctionalized graphene quantum dots based fluorescent biosensor towards efficient detection of small cell lung cancer
ACS Applied Bio Materials, 3(8), 4922–4932.
Contributors: A. Kalkal *, R. Pradhan *, * , G. Manik * & G. Packirisamy
TL;DR:
A label-free and efficient fluorescent biosensor based on nanosurface energy transfer (NSET) between anti-NSE/amine-N-GQDs and AuNPs has been developed for neuron-specific enolase (NSE) detection.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2020 journal article
Fabrication and Analysis of ZnO Quantum Dots Based Easy Clean Coating: A Combined Theoretical and Experimental Investigation
ChemistrySelect, 5(29), 8942–8950.
Contributors: S. Sethi *, * , Anubhav, Goel, R. Chauhan * & G. Manik *
Source: ORCID
Added: September 12, 2023
2020 journal article
Recent advancements in synthesis and property control of graphene quantum dots for biomedical and optoelectronic applications
Materials Chemistry Frontiers, 5(2), 627–658.
Contributors: * , S. Sethi * & G. Manik *
TL;DR:
In this review, various top-down and bottom-up synthetic procedures to prepare GQDs with ease are summarized and several strategies adopted by researchers such as heteroatom doping, functionalization and controlling the reaction parameters to regulate their structure and chemical behavior are discussed.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2020 journal article
Sulfur doped graphene quantum dots as a potential sensitive fluorescent probe for the detection of quercetin
Food Chemistry, 317.
Contributors: * & G. Manik *
TL;DR:
It was observed that fluorescence intensity of SGQDs could be substantially quenched by the addition of quercetin through inner filter effect (IFE) mechanism, which revealed good linearity in the 0-50.0 μM range with regression coefficient and a lowest detection limit of 0.006 μg/mL.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2020 journal article
Synthesis, characterization and investigation of synergistic antibacterial activity and cell viability of silver–sulfur doped graphene quantum dot (Ag@S-GQDs) nanocomposites
Journal of Materials Chemistry B, 8(15), 3028–3037.
Contributors: * , G. Manik *, N. Das *, P. Nehra *, R. Chauhan * & P. Roy *
TL;DR:
Improved antibacterial and biocompatibility data demonstrate that the Ag@S-GQDs nanocomposite can serve as a promising antibacterial agent for industry to fabricate next-generation self-sterile textiles, antibacterial coatings and useful health care products supporting cell viability.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2020 journal article
Targeted bioimaging and sensing of folate receptor positive cancer cells using folic acid conjugated sulfur doped graphene quantum dots
Microchimica Acta, 187(8).
Contributors: * , G. Manik *, N. Das * & P. Roy *
TL;DR:
The experimental studies revealed that FA-SGQDs aptly entered into FR-positive cancer cells via a non-immunogenic FR-mediated endocytosis process and hold high promise to serve as efficient fluorescent nanoprobes for the pre- diagnosis of cancer through targeted bioimaging and other pertinent biological studies.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2023
2019 journal article
Effect of sulfur doping on fluorescence and quantum yield of graphene quantum dots: An experimental and theoretical investigation
Nanotechnology, 30(43).
Contributors: * , G. Manik *, A. Kalkal *, M. Singh * & R. Chauhan *
TL;DR:
These successfully demonstrated unique and improved properties of S-GQDs present them as a potential candidate for biomedical, optical, electrical and chemical applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: September 12, 2023
2018 journal article
Synthesis and Application of PHT-TiO<inf>2</inf> Nanohybrid for Amperometric Glucose Detection in Human Saliva Sample
Electroanalysis, 30(11), 2793–2802.
Contributors: * , B. Arya *, S. Kumar *, S. Sharma *, R. Chauhan *, A. Srivastava *, P. Chandra *, S. Singh *
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: September 12, 2023
Employment
Updated: November 16th, 2022 12:40
2022 - present
University of North Carolina NC, NC, US
Postdoctoral Research Scholar
Joint Department of Biomedical Engineering,The University of North Carolina and NC State University, USA.
2021 - 2022
Purdue University West Lafayette, Indiana, US
Postdoctoral Research Assistant
School of Materials Engineering
2021 - 2021
University of Alberta Edmonton, AB, CA
Overseas Visiting Doctoral Fellow
Electrical and computer engineering
Funding History
Funding history based on the linked ORCID record. Updated: November 16th, 2022 13:19
grant
February 1 - August 1, 2021
Systematic investigation of ultrafast events of excitons at GQDs/halide perovskite interface for optoelectronics applications
Science and Engineering Research Board
salary-award
Post graduate Scholarship (GATE)
All India Council for Technical Education
award
Institute Teaching Assistantship
Indian Institute of Technology Roorkee
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