Works (5)

Updated: July 5th, 2023 15:35

2022 journal article

Multiple Infusion Start Time Mass Spectrometry Imaging of Dynamic SIL-Glutathione Biosynthesis Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

JOURNAL OF PROTEOME RESEARCH, 21(3), 747–757.

By: A. Mellinger n, K. Garrard n, S. Khodjaniyazova n, Z. Rabbani n, M. Gamcsik n & D. Muddiman n

author keywords: IR-MALDESI; mass spectrometry imaging; stable isotope labeling; glutathione; kinetic metabolism
MeSH headings : Animals; Glutathione; Glycine; Lasers; Mice; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: A study combining a multiple infusion start time protocol, stable isotope labeling technology, infrared matrix-assisted laser desorption electrospray ionization, and high-resolution accurate mass-mass spectrometry imaging to study spatial changes in glutathione kinetics across in sectioned mouse liver tissues is presented. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: May 2, 2022

2020 journal article

A Versatile Platform for Mass Spectrometry Imaging of Arbitrary Spatial Patterns

Journal of the American Society for Mass Spectrometry, 31(12), 2547–2552.

By: K. Garrard n, M. Ekelöf n, S. Khodjaniyazova n, M. Bagley n & D. Muddiman n

author keywords: Mass Spectrometry Imaging; Arbitrary Region of Interest; MALDESI; Vision-System
TL;DR: A vision-system driven platform, RastirX, has been constructed for mass spectrometry imaging (MSI) of arbitrary two-dimensional patterns that reduces contamination from off-sample material and significantly reduces acquisition time. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: January 19, 2021

2020 journal article

Three-Dimensional Imaging with Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 31(2), 292–297.

By: H. Bai n, S. Khodjaniyazova n, K. Garrard n & D. Muddiman n

author keywords: mass spectrometry imaging; 3D; IR-MALDESI; MUPS; HRAM
MeSH headings : Anti-Ulcer Agents / analysis; Citrates / analysis; Imaging, Three-Dimensional / methods; Omeprazole / analysis; Pharmaceutical Preparations / chemistry; Proton Pump Inhibitors / analysis; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Starch / analysis; Tablets, Enteric-Coated / chemistry
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Sources: Web Of Science, NC State University Libraries
Added: March 10, 2020

2019 journal article

Mass spectrometry imaging (MSI) of fresh bones using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI)

ANALYTICAL METHODS, 11(46), 5929–5938.

By: S. Khodjaniyazova n, N. Hanne n, J. Cole n & D. Muddiman n

MeSH headings : Animals; Diagnostic Imaging; Lasers; Mice; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
TL;DR: An effective strategy for direct analysis and two-dimensional matrix-assisted laser desorption electrospray ionization (IR-MALDESI) mass spectrometry imaging (MSI) of mouse bones that underwent no chemical treatments prior to analysis is reported. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 16, 2019

2017 journal article

Direct screening of enzyme activity using infrared matrix-assisted laser desorption electrospray ionization

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 31(22), 1868–1874.

By: M. Nazari n, M. Ekelof n, S. Khodjaniyazova n, N. Elsen*, J. Williams* & D. Muddiman n

MeSH headings : Drug Discovery / methods; Enzyme Assays / methods; High-Throughput Screening Assays / methods; Isocitrate Dehydrogenase / metabolism; Isocitrates / metabolism; Ketoglutaric Acids / metabolism; Models, Chemical; NADP / metabolism; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: The utility of infrared matrix-assisted laser desorption electrospray ionization for monitoring an enzymatic reaction directly from a biological buffer system with no sample cleanup and at high throughput is presented. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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