Sara K Lyle

Works (19)

Updated: March 6th, 2026 14:16

2025 article

Infertility caused by oophoritis in a dog resolved by hemiovariectomy

Nebel-Karp, A., Mahoney, D., Whitacre, M., Bauer, B., & Lyle, S. (2025, January 10). Clinical Theriogenology.

By: A. Nebel-Karp, D. Mahoney, M. Whitacre n, B. Bauer & S. Lyle n

topics (OpenAlex): Assisted Reproductive Technology and Twin Pregnancy; Reproductive Biology and Fertility; Ectopic Pregnancy Diagnosis and Management
Source: NC State University Libraries
Added: March 4, 2026

2021 article

Evidence for anti‐inflammatory effects of firocoxib administered to mares with experimentally induced placentitis

Macpherson, M. L., Giguère, S., Pozor, M. A., Burden, C. A., Berghaus, L. J., Berghaus, R. D., … Horohov, D. W. (2021, February 10). American Journal of Reproductive Immunology.

By: M. Macpherson *, S. Giguère *, M. Pozor*, C. Burden *, L. Berghaus *, R. Berghaus *, J. Varner*, J. Hayna* ...

author keywords: anti‐ inflammatory; cytokine; equine; firocoxib; placentitis; pregnancy; prostaglandin
MeSH headings : 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / therapeutic use; Animals; Anti-Inflammatory Agents / therapeutic use; Cyclooxygenase 2 Inhibitors / therapeutic use; Female; Horse Diseases / drug therapy; Horses; Inflammation / drug therapy; Interleukin-6 / metabolism; Matrix Metalloproteinase 1 / metabolism; Placenta / metabolism; Placenta / pathology; Placenta Diseases / drug therapy; Pregnancy; Prostaglandins / metabolism; Sulfones / therapeutic use; Tumor Necrosis Factor-alpha / metabolism
topics (OpenAlex): Preterm Birth and Chorioamnionitis; Reproductive Physiology in Livestock; Pregnancy-related medical research
TL;DR: The goal of this study was to characterize the anti‐inflammatory effects of firocoxib when administered to mares with placentitis. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: March 8, 2021

2020 article

Metabolomic Profile of Allantoic and Amniotic Fluid in Late-term Gestational Mares Characterized by 1H-nuclear Magnetic Resonance Spectroscopy

Beachler, T. M., Bailey, C. S., Gracz, H. S., Morgan, D. R., Dollen, K. A. V., Ellis, K. E., … Lyle, S. K. (2020, August 24). Journal of Equine Veterinary Science, Vol. 94.

By: T. Beachler n, C. Bailey n, H. Gracz n, D. Morgan n, K. Dollen n, K. Ellis n, J. Gadsby n , S. Lyle n

author keywords: Equine; Metabolomics; Allantoic; Amniotic; Nuclear magnetic resonance spectroscopy
MeSH headings : Allantois; Amniotic Fluid; Animals; Body Fluids; Female; Horses; Magnetic Resonance Spectroscopy; Pregnancy; Protons
topics (OpenAlex): Reproductive Physiology in Livestock; Ruminant Nutrition and Digestive Physiology; Fatty Acid Research and Health
TL;DR: The goal of this study was to characterize the global metabolomic profile of equine allantoic and amniotic fluid through nuclear magnetic resonance spectroscopy offetal fluids from 12 pregnancies through ultrasound-guided transabdominal puncture. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020

2020 journal article

Plasma metabolomic profiling of healthy pregnant mares and mares with experimentally induced placentitis

Equine Veterinary Journal, 53(1), 85–93.

By: T. Beachler n, H. Gracz n, D. Morgan n, S. Bembenek Bailey  n, L. Borst n , K. Ellis n, K. Von Dollen n, S. Lyle n ...

author keywords: horse; placentitis; diagnosis; plasma; NMR spectroscopy; metabolomics
MeSH headings : Animals; Female; Horse Diseases; Horses; Metabolomics; Placenta Diseases / veterinary; Plasma; Pregnancy; Streptococcus equi
topics (OpenAlex): Metabolomics and Mass Spectrometry Studies; Reproductive Physiology in Livestock; Ruminant Nutrition and Digestive Physiology
TL;DR: Two phases of metabolite changes were noted after experimental infection: An immediate rise in metabolite concentration involved in energy, nitrogen, hydrogen, and oxygen metabolism within 4 hours after inoculation that was followed by a decrease in metabolites involved inenergy and nitrogen metabolism at 4 days, coinciding with ultrasonographic diagnosis of placentitis. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020

2019 article

Antimicrobial Activity of Ceftiofur and Penicillin With Gentamicin Against Escherichia coli and Streptococcus equi Subspecies zooepidemicus in an Ex Vivo Model of Equine Postpartum Uterine Disease

Dollen, K. A. V., Jones, M., Beachler, T., Harris, T. L., Papich, M. G., Lyle, S. K., & Bailey, C. S. (2019, June 20). Journal of Equine Veterinary Science, Vol. 79, pp. 121–126.

By: K. Dollen n, M. Jones n, T. Beachler n, T. Harris n, M. Papich n , S. Lyle n, C. Bailey n

author keywords: E. coli; S. zooepidemicus; Postpartum mare; Antibiotic use
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Female; Gentamicins; Horse Diseases / drug therapy; Horses; Humans; Penicillins; Postpartum Period; Streptococcus equi; Uterine Diseases / drug therapy; Uterine Diseases / veterinary
topics (OpenAlex): Reproductive Physiology in Livestock; Veterinary Equine Medical Research; Animal health and immunology
TL;DR: The intrauterine infusion of procaine penicillin G with gentamicin in cases of postpartum uterine disease caused by E. coli or S. zooepidemicus is supported by the results of this work. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 26, 2019

2019 article

Stallion Sperm Integrity After Centrifugation to Reduce Seminal Plasma Concentration and Cool Storage for 4 days

Len, J., Beehan, D., Eilts, B., Ebrahimie, E., & Lyle, S. (2019, November 4). Journal of Equine Veterinary Science.

By: J. Len *, D. Beehan*, B. Eilts*, E. Ebrahimie * & S. Lyle*

author keywords: Stallion; Centrifugation; Sperm motility; Plasma membrane and cool storage
MeSH headings : Animals; Centrifugation / veterinary; Horses; Male; Semen; Semen Analysis / veterinary; Sperm Motility; Spermatozoa
topics (OpenAlex): Sperm and Testicular Function; Reproductive Biology and Fertility; Ovarian function and disorders
TL;DR: A single centrifugation cycle to reduce seminal plasma concentration will suffice to preserve sperm integrity acceptable for an artificial insemination dose up to 4 days of cool storage. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 3, 2020

2018 article

Allantoic Metabolites, Progesterone, and Estradiol-17β Remain Unchanged After Infection in an Experimental Model of Equine Ascending Placentitis

Beachler, T., Gracz, H., Long, N. M., Borst, L., Morgan, D., Nebel, A., … Bailey, C. S. (2018, November 29). Journal of Equine Veterinary Science, Vol. 73, pp. 95–105.

By: T. Beachler n, H. Gracz n, N. Long *, L. Borst n , D. Morgan n, A. Nebel n, N. Andrews n, J. Koipillai n ...

author keywords: Equine; Ascending placentitis; Metabolomics; Allantoic fluid
topics (OpenAlex): Reproductive Physiology in Livestock; Ruminant Nutrition and Digestive Physiology; Genetic and phenotypic traits in livestock
TL;DR: The results of this study established a database of equine allantoic fluid metabolites and confirmed the utility of uteroplacental ultrasound for detection of placentitis before the onset of hematologic changes. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: February 11, 2019

2018 journal article

Alterations of the CTUP in Response to Ascending Placentitis Precede Changes in Hematologic Inflammatory Markers and Changes in Allantoic Metabolites

Journal of Equine Veterinary Science, 66, 237.

By: T. Beachler  n, H. Gracz n, D. Morgan n, K. Von Dollen  n, K. Ellis n, S. Lyle n, S. Bailey n, A. Nebel n ...

topics (OpenAlex): Fluorine in Organic Chemistry; Synthesis and Reactions of Organic Compounds; Inflammatory mediators and NSAID effects
Source: Crossref
Added: February 21, 2020

2018 journal article

Antimicrobial Activity in Equine Postpartum Uterine Fluid

Journal of Equine Veterinary Science, 66, 161.

By: K. VonDollen n, T. Beachler  n, S. Lyle n, C. Mowa *, M. Jones n, T. Harris n, C. Bailey n

topics (OpenAlex): Pharmacological Effects and Toxicity Studies; Sperm and Testicular Function; Testicular diseases and treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: February 21, 2020

2018 journal article

Characteristics of Dogs with Biofilm‐Forming Escherichia Coli Urinary Tract Infections

Journal of Veterinary Internal Medicine, 32(5), 1645–1651.

By: Z. Kern n, M. Jacob n, J. Gilbertie  n, S. Vaden n  & S. Lyle n

author keywords: chronic urinary tract infection; crystal violet; multidrug resistance; symptomatic urinary tract infection
MeSH headings : Animals; Biofilms / growth & development; Cross-Sectional Studies; Dog Diseases / microbiology; Dogs; Drug Resistance, Multiple, Bacterial; Escherichia coli / physiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / veterinary; Female; Male; Retrospective Studies; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary
topics (OpenAlex): Urinary Tract Infections Management; Gut microbiota and health; Reproductive tract infections research
TL;DR: The potential for biofilm formation should be considered whenever E. coli UTI is diagnosed and the association of antibiotic resistance and biofilm potential may affect treatment of UTIs, but additional investigation is warranted. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: November 5, 2018

2018 journal article

Gene Characterization of Biofilm-forming Escherichia coli Equine Reproductive Tract Isolates

Journal of Equine Veterinary Science, 66, 116.

By: S. Frable n, D. Beehan*, M. Jacob  n, A. Rogers  n, K. Ellis n, K. Von Dollen n, T. Beachler  n, C. Bailey n, S. Lyle n

topics (OpenAlex): Cervical Cancer and HPV Research; Microbial infections and disease research; Genital Health and Disease
Source: Crossref
Added: February 21, 2020

2018 journal article

Inflammatory Mediator Production in Fetal Fluids after Firocoxib Treatment in Mares with Experimentally-induced Placentitis

Journal of Equine Veterinary Science, 66, 227.

By: M. Macpherson *, S. Giguère *, M. Pozor*, C. Burden *, J. Hayna*, L. Berghaus *, S. Randell*, S. Benson* ...

topics (OpenAlex): Ovarian cancer diagnosis and treatment; Reproductive System and Pregnancy; Reproductive Physiology in Livestock
Source: Crossref
Added: February 21, 2020

2018 article

Pharmacokinetics of Intrarectal Altrenogest in Horses

Ellis, K. E., Dollen, K. A. V., Beachler, T. M., Bailey, C. S., Davis, J. L., & Lyle, S. K. (2018, October 10). Journal of Equine Veterinary Science.

By: K. Ellis n, K. Dollen n, T. Beachler n, C. Bailey n, J. Davis* & S. Lyle

author keywords: Horse; Altrenogest; Pharmacokinetics; Intrarectal administration
MeSH headings : Administration, Rectal; Animals; Cross-Over Studies; Female; Horses / metabolism; Pregnancy; Pregnancy Maintenance / drug effects; Trenbolone Acetate / analogs & derivatives; Trenbolone Acetate / pharmacokinetics
topics (OpenAlex): Reproductive Physiology in Livestock; Veterinary Equine Medical Research; Preterm Birth and Chorioamnionitis
TL;DR: Altrenogest is rapidly absorbed following PR administration in the horse and reaches therapeutic concentrations, making this a viable method of treatment in NPO mares, and the decreased bioavailability and shorter detection time suggest 0.088 mg/kg PR q 4–8 hours would be necessary to maintain therapeutic concentrations over a 24‐hour period. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: January 7, 2019

2018 article

Sperm quality during extra‐gonadal sperm reserve depletion in stallions

Len, J. A., Beehan, D., Eilts, B., & Lyle, S. K. (2018, October 13). Reproduction in Domestic Animals.

By: J. Len *, D. Beehan*, B. Eilts* & S. Lyle*

author keywords: EGR and sperm output; plasma membrane; sperm; stallion
MeSH headings : Animals; Cell Membrane; Cryopreservation / methods; Cryopreservation / veterinary; Gonads / physiology; Horses; Male; Semen Preservation / methods; Semen Preservation / veterinary; Sperm Motility / physiology; Spermatozoa / physiology
topics (OpenAlex): Sperm and Testicular Function; Reproductive Biology and Fertility; Reproductive Physiology in Livestock
TL;DR: To estimate when, during stallions' extra-gonadal reserves (EGR) depletion period, sperm quality would reach its highest quality, six light breed sexually rested stallions were collected daily for 7 days to deplete EGR. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 11, 2019

2015 journal article

The Evaluation of Biofilm-Forming Potential of Escherichia coli Collected From the Equine Female Reproductive Tract

Journal of Equine Veterinary Science, 35(11-12), 935–939.

By: D. Beehan*, K. Wolfsdorf*, J. Elam*, N. Krekeler *, D. Paccamonti * & S. Lyle*

author keywords: Mare; Uterus; Biofilm; Equine; Endometritis; Escherichia coli
topics (OpenAlex): Escherichia coli research studies; Clostridium difficile and Clostridium perfringens research; Bacterial Identification and Susceptibility Testing
TL;DR: The results strongly support the theory that biofilm formation may be an important cause of chronic endometrial infection in mares. (via Semantic Scholar)
Source: Crossref
Added: February 24, 2020

2013 journal article

Dr. Atwood C. Asbury

Journal of Equine Veterinary Science, 34(1), 1.

By: S. Lyle*

topics (OpenAlex):
Source: Crossref
Added: December 29, 2020

2013 journal article

Effect of contextually congruent stallion vocalization playback on intrauterine pressure in the mare

Journal of Equine Veterinary Science, 34(1), 131.

By: S. Lyle*, R. Durand *, V. Taylor*, E. Oostelaar*, D. Beehan*, D. Paccamonti*, S. McDonnell *

topics (OpenAlex): Reproductive Physiology in Livestock; Veterinary Equine Medical Research
TL;DR: It is hypothesized that teasing, contextually congruent stallion vocalization (with or without stallion scent), and exogenous oxytocin would increase intrauterine pressure in estrous pony mares, but that oxytoc in would cause the greatest increases in intrauterne pressure. (via Semantic Scholar)
Source: Crossref
Added: February 24, 2020

2011 journal article

Effect of a Single Injection of Long-acting Progesterone on the First Ovulation in Early and Late Spring Transitional Mares

Journal of Equine Veterinary Science, 31(12), 744–748.

By: S. Staempfli*, S. Clavier*, D. Thompson*, P. Burns, S. Lyle* & A. McKinnon*

author keywords: Progestins; Progesterone; Transition; Mare; Ovulation
topics (OpenAlex): Reproductive Physiology in Livestock; Veterinary Equine Medical Research; Entomological Studies and Ecology
TL;DR: Investigation of the use of a new compounded controlled-release progesterone preparation in early and late spring transitional mares found it to be a simple and effective method of controlling the first ovulation of the season in late transitional mare. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2009 journal article

174 TRANSCERVICAL EMBRYO COLLECTION IN THE DOMESTIC BITCH

Reproduction, Fertility and Development, 22(1), 245.

By: B. Eilts*, J. Len *, C. Pope*, P. Pennington *, M. Vermeulen *, M. Graham*, C. Hedlund*, S. Vasanjee*, S. Lyle*, R. Godke*

topics (OpenAlex): Veterinary Medicine and Surgery; Reproductive Physiology in Livestock; Veterinary Equine Medical Research
TL;DR: Nonsurgical embryo recovery in the bitch was most likely unsuccessful, compared to the authors' and previous work, due to inabilities to pass a cystoscope into the cranial vagina, and to create uterine distension using a small volume of medium. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.