Slavko Komarnytsky

Activation of extraoral bitter taste receptors by herbs and spices in the regulation of incretin signaling and glucose metabolism

Komarnytsky, S., Mhawish, R., & Wagner, C. (2026, February 11).

Capsaicinoid Profiles, Phenolic Content, and Antioxidant Properties of Chili Peppers Grown in Urban Settings

Alghamdi, M., Rathinasabapathy, T., & Komarnytsky, S. (2025, May 20). International Journal of Molecular Sciences, Vol. 26.

Cottonseed oil composition and its application to skin health and personal care

Gutierrez, J., & Komarnytsky, S. (2025, March 19). Frontiers in Pharmacology, Vol. 16.

Metabolic reset purification program improves antioxidant balance and gut microbiome in individuals transitioning to a healthier diet

Panda, C., Kruse, R., Williams, K., Nance, B., Gudavalli, M., Pourafshar, S., … Komarnytsky, S. (2025, August 11). Frontiers in Nutrition, Vol. 12.

Nutrient–Nutrient Interactions Among Broccoli Glucosinolates and Their Implications for Breeding Cruciferous Crops to Enhance Human Health

Bussler, W., DeZego, K., Chandler, H., Reid, R. W., & Komarnytsky, S. (2025, January 18). Nutrients, Vol. 17.

Small Phenolic Metabolites at the Nexus of Nutrient Transport and Energy Metabolism

Mhawish, R., & Komarnytsky, S. (2025, February 24). Molecules, Vol. 2.

Biomarkers of Metabolic Adaptation to High Dietary Fats in a Mouse Model of Obesity Resistance

Milhem, F., Hamilton, L. M., Skates, E., Wilson, M., Johanningsmeier, S. D., & Komarnytsky, S. (2024, January 20). Metabolites, Vol. 14.

Bitter Phytochemicals Acutely Lower Blood Glucose Levels by Inhibition of Glucose Absorption in the Gut

Jackson, K. M. P., Mhawish, R., & Komarnytsky, S. (2024, July 25). Endocrines.

Comfort Foods in the Twenty-First Century: Friend or Foe?

Holt, R. R., Schmitz, H. H., Mhawish, R., Komarnytsky, S., Nguyen, T., Caveney, P. M., & Munafo, J. P. (2024, December 11). Annual Review of Food Science and Technology, Vol. 16, pp. 433–458.

Comparative evaluation of the antioxidant and anti-inflammatory potential of fennel essential oil obtained by conventional and supercritical fluid extraction

Tanveer, M., Shehzad, A., Komarnytsky, S., Butt, M. S., Shahid, M., & Aadil, R. M. (2024, February 15). Biomass Conversion and Biorefinery, Vol. 2.

Efficacy and tolerability of full spectrum hemp oil in dogs living with pain in common household settings

Panda, C., Rathinasabapathy, T., Metzger, B., Dodson, S., Hanson, D., Griffiths, J., & Komarnytsky, S. (2024, July 12). Frontiers in Veterinary Science, Vol. 11.

Functional recovery following traumatic brain injury in rats is enhanced by oral supplementation with bovine thymus extract

Surzenko, N., Bastidas, J., Reid, R. W., Curaba, J., Zhang, W., Bostan, H., … El‐Khodor, B. F. (2024, February 5). The FASEB Journal, Vol. 38.

Obesity-Resistant Mice on a High-Fat Diet Display a Distinct Phenotype Linked to Enhanced Lipid Metabolism

Milhem, F., Skates, E., Wilson, M., & Komarnytsky, S. (2024, January 4). Nutrients, Vol. 16.

Triptolide Administration Alters Immune Responses to Mitigate Insulin Resistance in Obese States

Grodsky, L., Wilson, M., Rathinasabapathy, T., & Komarnytsky, S. (2024, March 25). Biomolecules, Vol. 14.

Alleviation of Pain, PAIN Interference, and Oxidative Stress by a Novel Combination of Hemp Oil, Calamari Oil, and Broccoli: A Randomized, Double-Blind, Placebo-Controlled Trial

Carlisle, C., Polley, K., Panda, C., Barron, K., Hamrock, M., Dominique, A., … Komarnytsky, S. (2023, June 7). Nutrients, Vol. 15.

Berries in Microbiome-Mediated Gastrointestinal, Metabolic, and Immune Health

Komarnytsky, S., Wagner, C., Gutierrez, J., & Shaw, O. M. (2023, February 4). Current Nutrition Reports, Vol. 2.

Current Status and Nutritional Value of Green Leaf Protein

Balfany, C., Gutierrez, J., Moncada, M., & Komarnytsky, S. (2023, March 8). Nutrients, Vol. 15.

Guided Metabolic Detoxification Program Supports Phase II Detoxification Enzymes and Antioxidant Balance in Healthy Participants

Panda, C., Komarnytsky, S., Fleming, M. N., Marsh, C., Barron, K., Brun-Blashka, S. L., & Metzger, B. (2023, May 6). Nutrients, Vol. 15.

Progression to Obesity: Variations in Patterns of Metabolic Fluxes, Fat Accumulation, and Gastrointestinal Responses

Milhem, F., & Komarnytsky, S. (2023, September 15). Metabolites, Vol. 13.

Total Utilization-Upcycling of Mushroom Protein By-Product: Characterization and Assessment as an Alternative Batter Ingredient for Fried Shrimp

Garcia, D., You, S. W., Aleman, R. S., King, J. M., Komarnytsky, S., Hoskin, R. T., & Moncada, M. (2023, February 9). Foods, Vol. 12.

All Polyphenols Are Not Created Equal: Exploring the Diversity of Phenolic Metabolites

Vong, C. I., Rathinasabapathy, T., Moncada, M., & Komarnytsky, S. (2022, February 11). Journal of Agricultural and Food Chemistry, Vol. 70, pp. 2077–2091.

Effect of Wild Blueberry Metabolites on Biomarkers of Gastrointestinal and Immune Health In Vitro

Rathinasabapathy, T., Lomax, J., Srikanth, K., Esposito, D., Kay, C. D., & Komarnytsky, S. (2022, March 25). Immuno, Vol. 2, pp. 293–306.

Essential Minerals and Metabolic Adaptation of Immune Cells

Alghamdi, M., Gutierrez, J., & Komarnytsky, S. (2022, December 27). Nutrients, Vol. 15.

Mushrooms as Functional and Nutritious Food Ingredients for Multiple Applications

You, S. W., Hoskin, R. T., Komarnytsky, S., & Moncada, M. (2022, June 8). ACS Food Science & Technology, Vol. 6.

Plant-Based Support of Respiratory Health during Viral Outbreaks

Rathinasabapathy, T., Sakthivel, L. P., & Komarnytsky, S. (2022, February 11). Journal of Agricultural and Food Chemistry, Vol. 70, pp. 2064–2076.

Endocannabinoid System and Its Regulation by Polyunsaturated Fatty Acids and Full Spectrum Hemp Oils

Komarnytsky, S., Rathinasabapathy, T., Wagner, C., Metzger, B., Carlisle, C., Panda, C., … Varadharaj, S. (2021, May 22). International Journal of Molecular Sciences, Vol. 22.

Gains and Losses of Agricultural Food Production: Implications for the Twenty-First Century

Komarnytsky, S., Retchin, S., Vong, C. I., & Lila, M. A. (2021, November 23). Annual Review of Food Science and Technology.

Immune Responses Are Differentially Regulated by Root, Stem, Leaf, and Flower Extracts of Female and Male CBD Hemp (Cannabis sativa L.) Plants

Esposito, L. G. A., Overbaugh, E., Xiong, J., Rathinasabapathy, T., Komarnytsky, S., Silva, D. J. H., & Esposito, D. A. (2021, October 22). Immuno.

Modulation of Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway by Culinary Sage (Salvia officinalis L.)

Chiang, N., Ray, S., Lomax, J., Goertzen, S., Komarnytsky, S., Ho, C.-T., & Munafo, J. P. (2021, July 9). International Journal of Molecular Sciences, Vol. 22, p. 7382.

Rheum rhaponticum Root Extract Improves Vasomotor Menopausal Symptoms and Estrogen-Regulated Targets in Ovariectomized Rat Model

Wilson, M., Konda, V., Heidt, K., Rathinasabapathy, T., Desai, A., & Komarnytsky, S. (2021, January 21). International Journal of Molecular Sciences, Vol. 22, p. 1032.

Celtic Provenance in Traditional Herbal Medicine of Medieval Wales and Classical Antiquity

Wagner, C., Gezelle, J. D., & Komarnytsky, S. (2020, February 28). Frontiers in Pharmacology, Vol. 11.

Enhanced stability of berry pomace polyphenols delivered in protein-polyphenol aggregate particles to an in vitro gastrointestinal digestion model

Xiong, J., Chan, Y. H., Rathinasabapathy, T., Grace, M. H., Komarnytsky, S., & Lila, M. A. (2020, June 12). Food Chemistry, Vol. 331, p. 127279.

Exploring the Anti-Acne Potential of Impepho [Helichrysum odoratissimum (L.) Sweet] to Combat Cutibacterium acnes Virulence

Canha, M. N. D., Komarnytsky, S., Langhansova, L., & Lall, N. (2020, January 30). Frontiers in Pharmacology, Vol. 10.

Spicing up gastrointestinal health with dietary essential oils

Tanveer, M., Wagner, C., Haq, M. I., Ribeiro, N. C., Rathinasabapathy, T., Butt, M. S., … Komarnytsky, S. (2020, March 4). Phytochemistry Reviews, Vol. 19, pp. 243–263.

The Enigma of Bioactivity and Toxicity of Botanical Oils for Skin Care

Moore, E. M., Wagner, C., & Komarnytsky, S. (2020, May 29). Frontiers in Pharmacology, Vol. 11.

Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling

Esposito, D., Overall, J., Grace, M. H., Komarnytsky, S., & Lila, M. A. (2019, September 27). Frontiers in Pharmacology, Vol. 10.

Phenylpropanoid Glycerol Glucosides Attenuate Glucose Production in Hepatocytes

Murray, A. F., Palatini, K., Komarnytsky, S., Gianfagna, T. J., & Munafo, J. P. (2019, June 19). ACS Omega, Vol. 4, pp. 10670–10676.

Botanical Provenance of Traditional Medicines From Carpathian Mountains at the Ukrainian-Polish Border

Kozlowska, W., Wagner, C., Moore, E. M., Matkowski, A., & Komarnytsky, S. (2018, April 5). Frontiers in Pharmacology, Vol. 9.

Anthocyanins in metabolic health and disease

Nutrigenomics and Proteomics in Health and Disease: towards a Systems-Level Understanding of Gene-Diet Interactions, 2nd Edition, 92–124.

Antibacterial activity of medicinal plants from The Physicians of Myddvai, a 14th century Welsh medical manuscript

Wagner, C. S., Gezelle, J. D., Robertson, M., Robertson, K., Wilson, M., & Komarnytsky, S. (2017, March 27). Journal of Ethnopharmacology, Vol. 203, pp. 171–181.

Berries containing anthocyanins with enhanced methylation profiles are more effective at ameliorating high fat diet-induced metabolic damage

Skates, E., Overall, J., DeZego, K., Wilson, M., Esposito, D., Lila, M. A., & Komarnytsky, S. (2017, November 28). Food and Chemical Toxicology, Vol. 111, pp. 445–453.

Health modifying regions in the oat (Avena sativa) genome responsible for beneficial effects on immune and gastrointestinal health

FASEB Journal, 31.

Metabolic Effects of Berries with Structurally Diverse Anthocyanins

Overall, J., Bonney, S., Wilson, M., Beermann, A., Grace, M., Esposito, D., … Komarnytsky, S. (2017, February 15). International Journal of Molecular Sciences, Vol. 18.

Phytoecdysteroid-enriched quinoa seed leachate enhances healthspan and mitochondrial metabolism in Caenorhabditis elegans

Graf, B. L., Kamat, S., Cheong, K. Y., Komarnytsky, S., Driscoll, M., & Di, R. (2017, July 24). Journal of Functional Foods, Vol. 37, pp. 1–7.

Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities

Chinese Journal of Natural Medicines, 15(11), 816–824.

Structural constraints and importance of caffeic acid moiety for anti-hyperglycemic effects of caffeoylquinic acids from chicory

Jackson, K. M. P., Rathinasabapathy, T., Esposito, D., & Komarnytsky, S. (2017, April 5). Molecular Nutrition & Food Research, Vol. 61.

Thiazolopyridines Improve Adipocyte Function by Inhibiting 11 Beta-HSD1 Oxoreductase Activity

Journal of Chemistry, 2017, 1–10.

Chemical composition, antioxidant and anti-inflammatory properties of pistachio hull extracts

Food Chemistry, 210, 85–95.

In vitro lipolytic, antioxidant and anti-inflammatory activities of roasted pistachio kernel and skin constituents

Food & Function, 7(10), 4285–4298.

Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes

Kellogg, J., Esposito, D., Grace, M. H., Komarnytsky, S., & Lila, M. A. (2015, April 14). Journal of Functional Foods, Vol. 15, pp. 396–407.

Black Currant Anthocyanins Attenuate Weight Gain and Improve Glucose Metabolism in Diet-Induced Obese Mice with Intact, but Not Disrupted, Gut Microbiome

Esposito, D., Damsud, T., Wilson, M., Grace, M. H., Strauch, R., Li, X., … Komarnytsky, S. (2015, June 12). Journal of Agricultural and Food Chemistry, Vol. 63, pp. 6172–6180.

Hepatoprotective Activity of Easter Lily (Lilium longiflorum Thunb.) Bulb Extracts

Tang, W., Munafo, J. P., Palatini, K., Esposito, D., Huang, M.-T., Komarnytsky, S., … Gianfagna, T. J. (2015, October 22). Journal of Agricultural and Food Chemistry, Vol. 63, pp. 9722–9728.

Vitamin E: Defining Status for Optimal Health

Bussler, W., Hildebrand, J., Mixon, C., Wagoner, T., Komarnytsky, S., & Harris, G. (2015, May 14). Dietary Supplements in Health Promotion, pp. 281–318.

1,25-Dihydroxyvitamin D3/vitamin D receptor suppresses brown adipocyte differentiation and mitochondrial respiration

Ricciardi, C. J., Bae, J., Esposito, D., Komarnytsky, S., Hu, P., Chen, J., & Zhao, L. (2014, October 8). European Journal of Nutrition, Vol. 54, pp. 1001–1012.

Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration

Bae, J., Ricciardi, C. J., Esposito, D., Komarnytsky, S., Hu, P., Curry, B. J., … Zhao, L. (2014, March 14). American Journal of Physiology-Cell Physiology, Vol. 306, pp. C918–930.

Cytotoxic Effects of Ellagitannins Isolated from Walnuts in Human Cancer Cells

Le, V., Esposito, D., Grace, M. H., Ha, D., Pham, A., Bortolazzo, A., … White, J. B. (2014, September 29). Nutrition and Cancer, Vol. 66, pp. 1304–1314.

Inhibitory Effects of Wild Blueberry Anthocyanins and Other Flavonoids on Biomarkers of Acute and Chronic Inflammation in Vitro

Esposito, D., Chen, A., Grace, M. H., Komarnytsky, S., & Lila, M. A. (2014, January 8). Journal of Agricultural and Food Chemistry, Vol. 62, pp. 7022–7028.

Acceleration of cutaneous wound healing by brassinosteroids

Esposito, D., Rathinasabapathy, T., Schmidt, B., Shakarjian, M. P., Komarnytsky, S., & Raskin, I. (2013, August 12). Wound Repair and Regeneration, Vol. 21, pp. 688–696.

Effects of Pregnane Glycosides on Food Intake Depend on Stimulation of the Melanocortin Pathway and BDNF in an Animal Model

Journal of Agricultural and Food Chemistry, 61(8), 1841–1849.

Steroidal glycosides from the bulbs of Easter lily (Lilium longiflorum Thunb.) promote dermal fibroblast migration in vitro

Esposito, D., Munafo, J. P., Lucibello, T., Baldeon, M., Komarnytsky, S., & Gianfagna, T. J. (2013, May 2). Journal of Ethnopharmacology, Vol. 148, pp. 433–440.

Hypoglycemic effects of brassinosteroid in diet-induced obese mice

Esposito, D., Kizelsztein, P., Komarnytsky, S., & Raskin, I. (2012, July 12). American Journal of Physiology-Endocrinology and Metabolism, Vol. 303, pp. E652–658.

Modulation of muscle mass and myogenic stem cells with natural products

Planta Medica, 78(11).

Modulation of muscle mass and myogenic stem cells with natural products

Planta Medica, 78(11), 1096–1096.

Plant‐Derived Antibodies for Academic, Industrial, and Therapeutic Applications

Komarnytsky, S., & Borisjuk, N. (2012, April 23). Antibody-Mediated Drug Delivery Systems, pp. 365–381.

Pregnane glycosides interfere with steroidogenic enzymes to down‐regulate corticosteroid production in human adrenocortical H295R cells

Komarnytsky, S., Esposito, D., Poulev, A., & Raskin, I. (2012, October 12). Journal of Cellular Physiology, Vol. 228, pp. 1120–1126.

Akt-Dependent Anabolic Activity of Natural and Synthetic Brassinosteroids in Rat Skeletal Muscle Cells

Journal of Medicinal Chemistry, 54(12), 4057–4066.

Anabolic effect of plant brassinosteroid

Esposito, D., Komarnytsky, S., Shapses, S., & Raskin, I. (2011, July 11). The FASEB Journal, Vol. 25, pp. 3708–3719.

Potato protease inhibitors inhibit food intake and increase circulating cholecystokinin levels by a trypsin-dependent mechanism

Komarnytsky, S., Cook, A., & Raskin, I. (2010, September 7). International Journal of Obesity, Vol. 35, pp. 236–243.

20-Hydroxyecdysone decreases weight and hyperglycemia in a diet-induced obesity mice model

Kizelsztein, P., Govorko, D., Komarnytsky, S., Evans, A., Wang, Z., Cefalu, W. T., & Raskin, I. (2009, January 7). American Journal of Physiology-Endocrinology and Metabolism, Vol. 296.

Oral administration of triptolide ameliorates the clinical signs of experimental autoimmune encephalomyelitis (EAE) by induction of HSP70 and stabilization of NF-κB/IκBα transcriptional complex

Kizelsztein, P., Komarnytsky, S., & Raskin, I. (2009, October 1). Journal of Neuroimmunology, Vol. 217, pp. 28–37.

Polyphenolic compounds fromArtemisia dracunculus L.inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line

Govorko, D., Logendra, S., Wang, Y., Esposito, D., Komarnytsky, S., Ribnicky, D., … Raskin, I. (2007, September 12). American Journal of Physiology-Endocrinology and Metabolism, Vol. 293.

Preparative isolation and identification of tyrosinase inhibitors from the seeds of Garcinia kola by high-speed counter-current chromatography

Okunji, C., Komarnytsky, S., Fear, G., Poulev, A., Ribnicky, D. M., Awachie, P. I., … Raskin, I. (2007, March 2). Journal of Chromatography A, Vol. 1151, pp. 45–50.

Cosecretion of Protease Inhibitor Stabilizes Antibodies Produced by Plant Roots

Komarnytsky, S., Borisjuk, N., Yakoby, N., Garvey, A., & Raskin, I. (2006, August 1). PLANT PHYSIOLOGY, Vol. 141, pp. 1185–1193.

Protease inhibitors and their peptidomimetic derivatives as potential drugs

Fear, G., Komarnytsky, S., & Raskin, I. (2006, September 23). Pharmacology & Therapeutics, Vol. 113, pp. 354–368.

A quick and efficient system for antibiotic-free expression of heterologous genes in tobacco roots

Komarnytsky, S., Gaume, A., Garvey, A., Borisjuk, N., & Raskin, I. (2004, April 22). Plant Cell Reports, Vol. 22, pp. 765–773.

Functional Analysis of Promoter Elements in Plants

Komarnytsky, S., & Borisjuk, N. (2003, January 1). Genetic Engineering, pp. 113–141.

Functional analysis of promoter elements in plants.

Genetic Engineering, 25, 113–141. http://www.scopus.com/inward/record.url?eid=2-s2.0-3543141756&partnerID=MN8TOARS

Rhizosecretion of recombinant proteins from plant hairy roots

Gaume, A., Komarnytsky, S., Borisjuk, N., & Raskin, I. (2003, August 1). Plant Cell Reports, Vol. 21, pp. 1188–1193.

Plants and human health in the twenty-first century

Raskin, I., Ribnicky, D. M., Komarnytsky, S., Ilic, N., Poulev, A., Borisjuk, N., … Fridlender, B. (2002, December 1). Trends in Biotechnology, Vol. 20, pp. 522–531.