Shuo Liu

Works (6)

Updated: September 5th, 2025 14:35

2025 article

Microneedle Delivery of Small Extracellular Vesicles From Young Blood to Treat Endothelial Senescence

Hu, S., Li, Z., Zhu, D., Liu, S., Xing, M., & Cheng, K. (2025, August 5). Advanced Materials.

By: S. Hu n , Z. Li n, D. Zhu n , S. Liu n, M. Xing * & K. Cheng *

author keywords: endothelium senescence; extracellular vesicles; microneedle patch; microRNA; umbilical cord plasma
topics (OpenAlex): Extracellular vesicles in disease; Photoacoustic and Ultrasonic Imaging; Cardiovascular Disease and Adiposity; Advancements in Transdermal Drug Delivery
Source: Web Of Science
Added: August 18, 2025

2024 article

An infusible biologically active adhesive for chemotherapy-related heart failure in elderly rats

Yao, J., Li, J., Zhu, D., Li, Y., Tasoudis, P., Liu, S., … Huang, K. (2024, July 26). Bioactive Materials, Vol. 40, pp. 571–581.

By: J. Yao *, J. Li n, D. Zhu n , Y. Li n , P. Tasoudis *, S. Liu n, X. Mei *, K. Popowski n  ...

author keywords: Secretomes; Cardiac stromal cells; Extracellular matrix; Chemotherapy; Heart failure; Intrapericardial injection
topics (OpenAlex): Tissue Engineering and Regenerative Medicine; Electrospun Nanofibers in Biomedical Applications; Cardiac Ischemia and Reperfusion
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 1, 2024

2024 article

Inhalable Stem Cell Exosomes Promote Heart Repair After Myocardial Infarction

Li, J., Sun, S., Zhu, D., Mei, X., Lyu, Y., Huang, K., … Cheng, K. (2024, August 26). Circulation, Vol. 150, pp. 710–723.

By: J. Li n, S. Sun, D. Zhu* , X. Mei*, Y. Lyu n, K. Huang n , Y. Li n , S. Liu* ...

author keywords: CD36; extracellular vesicles; exosomes; inhalation; myocardial infarction
MeSH headings : Animals; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardial Infarction / physiopathology; Exosomes / metabolism; Mice; Mice, Inbred C57BL; Administration, Inhalation; Disease Models, Animal; Swine; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Male; Ventricular Function, Left; Humans; Myocardium / metabolism; Myocardium / pathology; Stem Cells / metabolism; CD36 Antigens / metabolism; CD36 Antigens / genetics
topics (OpenAlex): Extracellular vesicles in disease; Cardiovascular Effects of Exercise; Tissue Engineering and Regenerative Medicine
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 1, 2024

2024 article

Inhalation of ACE2-expressing lung exosomes provides prophylactic protection against SARS-CoV-2

Wang, Z., Hu, S., Popowski, K. D., Liu, S., Zhu, D., Mei, X., … Cheng, K. (2024, March 12). Nature Communications, Vol. 15.

By: Z. Wang n, S. Hu* , K. Popowski n , S. Liu*, D. Zhu* , X. Mei n, J. Li*, Y. Hu * ...

MeSH headings : Cricetinae; Female; Animals; Humans; Mice; SARS-CoV-2; COVID-19; Angiotensin-Converting Enzyme 2; Exosomes; Tissue Distribution; Spike Glycoprotein, Coronavirus; Antibodies, Neutralizing
topics (OpenAlex): Extracellular vesicles in disease; SARS-CoV-2 and COVID-19 Research; COVID-19 Clinical Research Studies
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Sources: Web Of Science, NC State University Libraries
Added: April 8, 2024

2023 journal article

Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair

European Heart Journal, 44(19), 1748–1760.

By: D. Zhu n , S. Liu n, K. Huang n , J. Li n, X. Mei n, Z. Li n, K. Cheng n

author keywords: Myocardial infarction; Adverse remodelling; Mesenchymal stem cell; EVs; lncRNA; Tcf21
MeSH headings : Mice; Animals; Swine; RNA, Long Noncoding / genetics; RNA, Long Noncoding / metabolism; RNA, Antisense / genetics; RNA, Antisense / metabolism; Ventricular Remodeling; Myocardial Infarction / genetics; Myocardial Infarction / therapy; Myocardial Infarction / metabolism; Fibrosis; Demethylation
topics (OpenAlex): Cardiac Valve Diseases and Treatments; Cardiac Fibrosis and Remodeling; Cancer-related molecular mechanisms research
TL;DR: Novel mechanisms underlying EV therapy for improving adverse remodelling are established and a lncRNA therapy for cardiac fibrosis is proposed, which could be a promising way to treat myocardial fibrosis. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: April 4, 2023

2022 article

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3

Zhu, D., Liu, S., Huang, K., Wang, Z., Hu, S., Li, J., … Cheng, K. (2022, October 13). Circulation Research, Vol. 10, pp. E135–E150.

By: D. Zhu n , S. Liu n, K. Huang n , Z. Wang n, S. Hu n , J. Li n, Z. Li n, K. Cheng n

author keywords: exosomes; immunomodulation; mesesnchymal stem cell; myocardial infarction; regulatory T cell
MeSH headings : Humans; Exosomes / metabolism; Forkhead Box Protein O3 / genetics; Forkhead Box Protein O3 / metabolism; Mesenchymal Stem Cells / metabolism; Myocardial Infarction / pathology; Proto-Oncogene Proteins c-akt / metabolism; Signal Transduction; Heart Injuries / metabolism
topics (OpenAlex): Heat shock proteins research; Cardiac Fibrosis and Remodeling; Extracellular vesicles in disease
TL;DR: A novel mechanism underlying the immunomodulation effects of MSC exosomes is revealed and provides a promising candidate (PP2A/p-Akt/Foxo3 signaling pathway) with a favorable delivery route (intrapericardial injection) for cardiac repair. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 14, 2022

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