Works (1)

Updated: July 5th, 2023 15:49

2009 journal article

Expression and activity of COX-1 and 2 and 5-LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis

Journal of Orthopaedic Research, 27(9), 1204–1208.

By: B. Lascelles n, S. King n, S. Roe n, D. Marcellin-Little n & S. Jones n

author keywords: canine; osteoarthritis; cyclooxygenase; lipoxygenase; eicosanoids
MeSH headings : Animals; Arachidonate 5-Lipoxygenase / metabolism; Arthroplasty, Replacement, Hip; Cyclooxygenase 1 / metabolism; Cyclooxygenase 2 / metabolism; Dinoprostone / metabolism; Disease Models, Animal; Dogs; Femur Head / metabolism; Femur Head / pathology; Hip Joint / enzymology; Hip Joint / pathology; Leukotriene B4 / metabolism; Osteoarthritis, Hip / metabolism; Osteoarthritis, Hip / pathology; Osteoarthritis, Hip / surgery; Synovial Membrane / enzymology; Synovial Membrane / pathology
TL;DR: Both COX‐2 and 5‐LOX are appropriate targets for the management of pain associated with naturally occurring OA, evaluated in a naturally occurring canine model of secondary OA. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

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