Scott Laster

Mottin, M., Caesar, L. K., Brodsky, D., Mesquita, N. C. M. R., Oliveira, K. Z., Noske, G. D., … Laster, S. M. (2022). Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins. BIOORGANIC CHEMISTRY, 120. https://doi.org/10.1016/j.bioorg.2022.105649

Cortes, L. M., Brodsky, D., Chen, C., Pridgen, T., Odle, J., Snider, D. B., … Kaser, T. (2022). Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis. FRONTIERS IN ALLERGY, 3. https://doi.org/10.3389/falgy.2022.1029184

Gulledge, T. V., Collette, N. M., Mackey, E., Johnstone, S. E., Moazami, Y., Todd, D. A., … Laster, S. M. (2018). Mast cell degranulation and calcium influx are inhibited by an Echinacea purpurea extract and the alkylamide dodeca-2E,4E-dienoic acid isobutylamide. Journal of Ethnopharmacology, 212, 166–174. https://doi.org/10.1016/J.JEP.2017.10.012

Devlin, A. A., Halvorsen, P. J., Miller, J. C., & Laster, S. M. (2017). Il-10 deficient mice express IFN-gamma mRNA and clear Leptospira interrogans from their kidneys more rapidly than normal C57BL/6 mice. IMMUNOBIOLOGY, 222(5), 768–777. https://doi.org/10.1016/j.imbio.2017.02.004

Lila, M. A., Schneider, M., Devlin, A., Plundrich, N., Laster, S., & Foegeding, E. A. (2017). Polyphenol-enriched berry extracts naturally modulate reactive proteins in model foods. Food & Function, 8(12), 4760–4767. https://doi.org/10.1039/C7FO00883J

Kaur, A., Oberhofer, M., Juzumaite, M., Raja, H. A., Gulledge, T. V., Kao, D. N., … Cech, N. B. (2016). Secondary metabolites from fungal endophytes of Echinacea purpurea suppress cytokine secretion by macrophage-type cells. Natural Product Communications, 11(8), 1143–1146. https://doi.org/10.1177/1934578x1601100827

Leyte-Lugo, M., Todd, D., Gulledge, T., Juzumaite, M., Carter, F., Laster, S., & Cech, N. (2015). Cytokine-Suppressive Activity of a Hydroxylated Alkylamide from Echinacea purpurea. Planta Medica Letters, 2(01), e25–e27. https://doi.org/10.1055/S-0035-1557764

Todd, D. A., Gulledge, T. V., Britton, E. R., Oberhofer, M., Leyte-Lugo, M., Moody, A. N., … Cech, N. B. (2015). Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria. PLOS ONE, 10(5). https://doi.org/10.1371/journal.pone.0124276

Moazami, Y., Gulledge, T. V., Laster, S. M., & Pierce, J. G. (2015). Synthesis and biological evaluation of a series of fatty acid amides from Echinacea. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25(16), 3091–3094. https://doi.org/10.1016/j.bmcl.2015.06.024

Kao, D., Kaur, A., Raja, H. A., El-Elimat, T., Oberhofer, M., Juzumaite, M., … Oberlies, N. H. (2014). Chemical investigation of fungal endophytes from Echinacea purpurea. Planta Medica, 80(10). https://doi.org/10.1055/S-0034-1382406

Britton, E. R., Todd, D. A., Leyte-Lugo, M., Gulledge, T., Grubbs, L. F., Oberhofer, M., … Cech, N. B. (2014). Unraveling immunomodulatory activities of complex Echinacea purpurea extracts. Planta Medica, 80(10). https://doi.org/10.1055/S-0034-1382726

Pollara, J. J., Spesock, A. H., Pickup, D. J., Laster, S. M., & Petty, I. T. D. (2012). Production of prostaglandin E-2 in response to infection with modified vaccinia Ankara virus. VIROLOGY, 428(2), 146–155. https://doi.org/10.1016/j.virol.2012.03.019

Cecil, C. E., Davis, J. M., Cech, N. B., & Laster, S. M. (2011). Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis). International Immunopharmacology, 11(11), 1706–1714. https://doi.org/10.1016/j.intimp.2011.06.002

Cech, N. B., Kandhi, V., Davis, J. M., Hamilton, A., Eads, D., & Laster, S. M. (2010). Echinacea and its alkylamides: Effects on the influenza A-induced secretion of cytokines, chemokines, and PGE(2) from RAW 264.7 macrophage-like cells. INTERNATIONAL IMMUNOPHARMACOLOGY, 10(10), 1268–1278. https://doi.org/10.1016/j.intimp.2010.07.009

Pollara, J. J., Laster, S. M., & Petty, I. T. D. (2010). Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid. ANTIVIRAL RESEARCH, 88(3), 287–295. https://doi.org/10.1016/j.antiviral.2010.09.017

Oyegunwa, A. O., Sikes, M. L., Wilson, J. R., Scholle, F., & Laster, S. M. (2010). Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-kappa B-dependent transcription of TNF-alpha and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA. JOURNAL OF INFLAMMATION-LONDON, 7. https://doi.org/10.1186/1476-9255-7-59

Eads, D., Hansen, R. L., Oyegunwa, A. O., Cecil, C. E., Culver, C. A., Scholle, F., … Laster, S. M. (2009). Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines. JOURNAL OF INFLAMMATION-LONDON, 6. https://doi.org/10.1186/1476-9255-6-2

Culver, C. A., & Laster, S. M. (2007). Adenovirus type 5 exerts multiple effects on the expression and activity of cytosolic phospholipase A(2), cyclooxygenase-2, and prostaglandin synthesis. JOURNAL OF IMMUNOLOGY, 179(6), 4170–4179. https://doi.org/10.4049/jimmunol.179.6.4170

Maia, R. C., Culver, C. A., & Laster, S. M. (2006). Evidence against calcium as a mediator of mitochondrial dysfunction during apoptosis induced by arachidonic acid and other free fatty acids. JOURNAL OF IMMUNOLOGY, 177(9), 6398–6404. https://doi.org/10.4049/jimmunol.177.9.6398

Culver, C. A., Michalowski, S. A., Maia, R. C., & Laster, S. A. (2005). The anti-apoptotic effects of nordihydroguaiaretic acid: Inhibition of cPLA(2) activation during TNF-induced apoptosis arises from inhibition of calcium signaling. LIFE SCIENCES, 77(19), 2457–2470. https://doi.org/10.1016/j.lfs.2005.03.023

Draper, D. W., Harris, V. G., Culver, C. A., & Laster, S. M. (2004). Calcium and its role in the nuclear translocation and activation of cytosolic phospholipase A(2) in cells rendered sensitive to TNF-induced apoptosis by cycloheximide. JOURNAL OF IMMUNOLOGY, 172(4), 2416–2423. https://doi.org/10.4049/jimmunol.172.4.2416

Feng, W. H., Tompkins, M. B., Xu, J. S., Brown, T. T., Laster, S. M., Zhang, H. X., & McCaw, M. B. (2002). Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virus. VIROLOGY, 302(2), 363–372. https://doi.org/10.1006/viro.2002.1650

Feng, W. H., Laster, S. M., Tompkins, M., Brown, T., Xu, J. S., Altier, C., … McCaw, M. B. (2001). In utero infection by porcine reproductive and respiratory syndrome virus is sufficient to increase susceptibility of piglets to challenge by Streptococcus suis type II. JOURNAL OF VIROLOGY, 75(10), 4889–4895. https://doi.org/10.1128/JVI.75.10.4889-4895.2001

Wolf, L. A., & Laster, S. M. (1999). Characterization of arachidonic acid-induced apoptosis. Cell Biochemistry and Biophysics, 30(3), 353–368. https://doi.org/10.1007/bf02738119

O'Brien, J. B., Piddington, D. L., Voelkel-Johnson, C., Richards, D. J., Hadley, L. A., & Laster, S. M. (1998). Sustained phosphorylation of cytosolic phospholipase A(2) accompanies cycloheximide- and adenovirus-induced susceptibility to TNF. Journal of Immunology, 161(3), 1525–1532.