A dual wavelength-activatable gold nanorod complex for synergistic cancer treatment
Pacardo, D. B., Neupane, B., Rikard, S. M., Lu, Y., Mo, R., Mishra, S. R., … Gu, Z. (2015, January 1). Nanoscale, Vol. 7, pp. 12096–12103.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Drug Screening Assays, Antitumor; Gold / chemistry; Gold / pharmacology; HeLa Cells; Humans; Infrared Rays; Nanotubes / chemistry; Neoplasms / drug therapy; Photochemotherapy
topics (OpenAlex): Nanoparticle-Based Drug Delivery; Nanoplatforms for cancer theranostics; Gold and Silver Nanoparticles Synthesis and Applications; Nanocluster Synthesis and Applications
TL;DR:
This multifunctional AuNR-based system represents a novel theranostic strategy for spatiotemporal delivery of anticancer therapeutics and demonstrates enhanced anticancer efficacy through the synergistic combination of promoted drug release upon ultraviolet (UV) light irradiation and photothermal therapy upon infrared (IR) irradiation.
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