Works (8)

Updated: February 5th, 2026 14:56

2026 article

Myeloid cell-specific HMGB1 deficiency exaggerates mucoinflammatory responses but promotes bacterial clearance in mucoinflammatory lung disease

Mao, Y., Patial, S., & Saini, Y. (2026, January 12). Scientific Reports, Vol. 1.

By: Y. Mao n, S. Patial* & Y. Saini n

topics (OpenAlex): Advanced Glycation End Products research; Inflammation biomarkers and pathways; Immune cells in cancer; S100 Proteins and Annexins; Neonatal Respiratory Health Research
Sources: NC State University Libraries, NC State University Libraries
Added: January 13, 2026

2026 article

Single-cell transcriptomics reveal alveolar macrophages-specific responses in single-hit ozone exposure model in mice

Vo, T., Choudhary, I., Patial, S., & Saini, Y. (2026, January 2). American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 1.

By: T. Vo n, I. Choudhary n, S. Patial* & Y. Saini n

topics (OpenAlex): Air Quality and Health Impacts; Indoor Air Quality and Microbial Exposure; IL-33, ST2, and ILC Pathways
Sources: NC State University Libraries, NC State University Libraries, ORCID
Added: January 3, 2026

2025 article

Airway epithelial cell-specific deletion of EGFR modulates mucoinflammatory features of cystic fibrosis-like lung disease in mice

Choudhary, I., Paudel, K., Kumar, R., Sharma, A., Patial, S., & Saini, Y. (2025, May 8). Frontiers in Immunology, Vol. 16.

By: I. Choudhary n, K. Paudel n, R. Kumar n, A. Sharma n, S. Patial* & Y. Saini n

author keywords: EGFR; cystic fibrosis; <italic>Scnn1b</italic>-Tg+; airway epithelium; mucus obstruction
MeSH headings : Animals; ErbB Receptors / genetics; ErbB Receptors / metabolism; ErbB Receptors / deficiency; Cystic Fibrosis / immunology; Cystic Fibrosis / pathology; Cystic Fibrosis / metabolism; Cystic Fibrosis / genetics; Mice; Mice, Transgenic; Disease Models, Animal; Epithelial Cells / metabolism; Epithelial Cells / immunology; Respiratory Mucosa / pathology; Respiratory Mucosa / metabolism; Respiratory Mucosa / immunology; Inflammation; Lung / pathology; Lung / immunology; Lung / metabolism; Mice, Knockout; Bronchoalveolar Lavage Fluid / immunology; Mucus / metabolism
topics (OpenAlex): Neonatal Respiratory Health Research; Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis; Inhalation and Respiratory Drug Delivery
Sources: Web Of Science, NC State University Libraries
Added: May 27, 2025

2025 article

Prior acute ozone injury dampens Th2 responses to subsequent repetitive ozone exposures in mice

Paudel, K., Patial, S., & Saini, Y. (2025, December 9).

By: K. Paudel n, S. Patial* & Y. Saini n

topics (OpenAlex): Air Quality and Health Impacts; Indoor Air Quality and Microbial Exposure; Medical and Biological Ozone Research
Sources: NC State University Libraries, NC State University Libraries
Added: December 10, 2025

2025 article

Repetitive ozone exposure worsens features of muco-inflammatory disease in developed Scnn1b-Tg+ mice lungs

Vo, T., Patial, S., & Saini, Y. (2025, May 27). Frontiers in Toxicology, Vol. 7.

By: T. Vo n, S. Patial* & Y. Saini n

author keywords: ozone; mice; <italic>Scnn1b</italic>-Tg+; lung; inflammation
topics (OpenAlex): Air Quality and Health Impacts; Medical and Biological Ozone Research; Climate Change and Health Impacts
Sources: Web Of Science, NC State University Libraries
Added: June 23, 2025

2024 article

Airspaces-derived exosomes contain disease-relevant protein signatures in a mouse model of cystic fibrosis (CF)-like mucoinflammatory lung disease

Mao, Y., Suryawanshi, A., Patial, S., & Saini, Y. (2024, September 25). Frontiers in Pharmacology, Vol. 15.

By: Y. Mao n, A. Suryawanshi n, S. Patial* & Y. Saini n

author keywords: exosome; proteomics; airspace; Scnn1b-Tg+; lung; mucoinflammation
topics (OpenAlex): Extracellular vesicles in disease; Inhalation and Respiratory Drug Delivery; Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 1, 2024

2024 article

Cell-Specific Contribution of IL-4 Receptor α Signaling Shapes the Overall Manifestation of Allergic Airway Disease

Choudhary, I., Lamichhane, R., Singamsetty, D., Vo, T., Brombacher, F., Patial, S., & Saini, Y. (2024, September 10). American Journal of Respiratory Cell and Molecular Biology, Vol. 71, pp. 702–717.

author keywords: IL-4Ra; allergic asthma; cell-specific; inflammation; eosinophils
MeSH headings : Animals; Signal Transduction; Asthma / immunology; Asthma / metabolism; Asthma / pathology; Mice; Allergens / immunology; Interleukin-4 Receptor alpha Subunit / metabolism; Interleukin-4 Receptor alpha Subunit / immunology; Interleukin-4 Receptor alpha Subunit / genetics; Lung / pathology; Lung / metabolism; Lung / immunology; Mice, Inbred C57BL; Mice, Knockout; Epithelial Cells / metabolism; Epithelial Cells / immunology; Epithelial Cells / pathology; Receptors, Cell Surface
topics (OpenAlex): Asthma and respiratory diseases; IL-33, ST2, and ILC Pathways
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 27, 2024

2024 article

Protocol for X-ray irradiation of C57BL/6J recipient mice followed by the transplantation of mTomato-expressing bone marrow cells

Vo, T., Kumar, R., Lamichhane, R., Choudhary, I., Rekha, K. C., Mao, Y., … Saini, Y. (2024, December 18). STAR Protocols, Vol. 6.

By: T. Vo n, R. Kumar n, R. Lamichhane n, I. Choudhary n, K. Rekha n, Y. Mao n, K. Paudel n, A. Suryawanshi n ...

MeSH headings : Animals; Mice, Inbred C57BL; Mice; Bone Marrow Transplantation / methods; X-Rays; Bone Marrow Cells / cytology; Transplantation Chimera
topics (OpenAlex): Cancer Cells and Metastasis; Hematopoietic Stem Cell Transplantation; Immunotherapy and Immune Responses
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 19, 2024

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