Sarah Chetty Rowe

Works (1)

Updated: August 26th, 2024 08:19

2023 journal article

Overcoming biological barriers to improve treatment of a Staphylococcus aureus wound infection

CELL CHEMICAL BIOLOGY, 30(5), 513-+.

By: V. Papadopoulou n, A. Sidders *, K. Lu *, A. Velez*, P. Durham  n, D. Bui *, M. Angeles-Solano*, P. Dayton n, S. Rowe*

TL;DR: This study combat the two major barriers to successful aminoglycoside treatment against a biofilm-infected wound: limited antibiotic uptake and limited biofilm penetration by employing palmitoleic acid, a host-produced monounsaturated fatty acid that perturbs the membrane of gram-positive pathogens and induces gentamicin uptake. (via Semantic Scholar)
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Added: September 5, 2023

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