Works (2)

Updated: April 5th, 2024 09:31

2017 journal article

Prostaglandin synthesis by the porcine corpus luteum: effect of tumor necrosis factor-alpha


By: J. Chang n, S. Frandsen n & J. Gadsby n

author keywords: Pig; Corpus luteum; Prostaglandin; Tumor necrosis factor-alpha; Macrophage; Luteolytic sensitivity
MeSH headings : Aldehyde Reductase / analysis; Aldehyde Reductase / genetics; Animals; Cells, Cultured; Corpus Luteum / drug effects; Corpus Luteum / metabolism; Cyclooxygenase 2 / genetics; Dinoprost / analysis; Dinoprost / biosynthesis; Dinoprost / pharmacology; Dinoprostone / analysis; Dinoprostone / biosynthesis; Dinoprostone / metabolism; Female; Luteal Cells / metabolism; Luteolysis / drug effects; Prostaglandin-E Synthases / analysis; Prostaglandin-E Synthases / genetics; Prostaglandins / biosynthesis; RNA, Messenger / analysis; Sus scrofa / metabolism; Tumor Necrosis Factor-alpha / pharmacology
TL;DR: Although TNF-α increased COX2 and mPGES-1 mRNA, and PGE-2 secretion in vitro, it did not increase the PGF-2α:PGE2 ratio, and studies are currently directed toward exploring other pathways by which T NF-α induces LS in the porcine CL. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Early life adversity in piglets induces long-term upregulation of the enteric cholinergic nervous system and heightened, sex-specific secretomotor neuron responses


By: J. Medland n, C. Pohl*, L. Edwards n, S. Frandsen n, K. Bagley n, Y. Li*, A. Moeser*

author keywords: cholinergic neurons; early life adversity; enteric nervous system development; irritable bowel syndrome; porcine model
MeSH headings : Animals; Cholinergic Neurons / metabolism; Disease Models, Animal; Enteric Nervous System / metabolism; Female; Irritable Bowel Syndrome / metabolism; Male; Motor Neurons / metabolism; Sex Factors; Stress, Psychological / metabolism; Swine; Up-Regulation; Weaning
TL;DR: A porcine model of ELA, early weaning stress (EWS), is utilized to investigate the influence of Ela on the development and function of the enteric nervous system (ENS). (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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