Works (5)

Updated: April 5th, 2024 06:41

2021 journal article

Using rheology to quantify the effects of localized collagenase treatments on uterine fibroid digestion


By: R. Corder n, S. Gadi n, R. Vachieri*, F. Jayes*, J. Cullen n, S. Khan n, D. Taylor*

author keywords: Uterine fibroids; Collagenase; Drug delivery; Rheology; Histology
MeSH headings : Animals; Collagenases; Digestion; Female; Humans; Leiomyoma / drug therapy; Mice; Rheology; Treatment Outcome; Uterine Neoplasms
TL;DR: Rheological results from an in vivo digestion study in mice show a significant reduction in tissue modulus and increase in tissue viscoelasticity 7 days after a single injection of LQG+CCH, and show promise for development of injectable and localized enzymatic therapies for uterine fibroids and other dense tumors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: November 8, 2021

2019 journal article

Virus discovery reveals frequent infection by diverse novel members of the Flaviviridae in wild lemurs

ARCHIVES OF VIROLOGY, 164(2), 509–522.

By: M. Canuti*, C. Williams*, S. Sagan*, B. Munnink*, S. Gadi n, J. Verhoeven*, P. Kellam*, M. Cotten* ...

MeSH headings : Animals; Flaviviridae / classification; Flaviviridae / genetics; Flaviviridae / isolation & purification; Flaviviridae / physiology; Flaviviridae Infections / veterinary; Flaviviridae Infections / virology; Genetic Variation; Lemur / virology; Madagascar; Phylogeny; Primate Diseases / virology
TL;DR: The results support the current proposed model of virus-host co-divergence with frequent occurrence of cross-species transmission for these genera and highlight how the discovery of more members of the Flaviviridae can help clarify the ecology and evolutionary history of these viruses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: March 4, 2019

2014 journal article

Persistent viremia by a novel parvovirus in a slow loris (Nycticebus coucang) with diffuse histiocytic sarcoma


By: M. Canuti*, C. Williams*, S. Gadi n, M. Jebbink*, B. Munnink*, S. Farsani*, J. Cullen n, L. Hoek*

author keywords: parvovirus; virus discovery; slow loris; Nycticebus coucang; histiocytic sarcoma; VIDISCA; hematopoietic tumor; oncovirus
TL;DR: It is hypothesized that the virus could have benefitted from the constantly dividing cancer cells and may not have been the cause of the histiocytic sarcoma, and might bring new exciting opportunities in recognizing viruses to be used in cancer virotherapy. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Development of an Animal Model for Radiofrequency Ablation of Primary, Virally Induced Hepatocellular Carcinoma in the Woodchuck


By: C. Burke, J. Cullen*, A. State, S. Gadi*, K. Wilber, M. Rosenthal, A. Bulysheva, A. Pease, M. Mauro, H. Fuchs

MeSH headings : Animals; Biopsy; Carcinoma, Hepatocellular / pathology; Carcinoma, Hepatocellular / surgery; Carcinoma, Hepatocellular / virology; Catheter Ablation / instrumentation; Contrast Media; Equipment Design; Hepatitis B / complications; Hepatitis B / virology; Hepatitis B Virus, Woodchuck / pathogenicity; Liver Neoplasms, Experimental / pathology; Liver Neoplasms, Experimental / surgery; Liver Neoplasms, Experimental / virology; Magnetic Resonance Imaging; Marmota; Necrosis; Reproducibility of Results; Time Factors
TL;DR: A safe, reliable and consistent method was developed to study RF ablation of spontaneous primary HCC using chronically WHV-infected woodchucks, an animal model of hepatitis B virus-induced HCC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

3D volumes constructed from pixel-based images by digitally clearing plant and animal tissue

Journal of Microscopy, 240(2), 122–129.

By: D. Livingston n, T. Tuong n, S. Gadi n, C. Haigler n, R. Gelman & J. Cullen n

author keywords: Adobe After Effects; biopsy; frozen plant; in situ hybridization; light microscopy; liver; lung; paraffin; radiofrequency ablation; tumour; 3D reconstruction
MeSH headings : Animals; Avena / anatomy & histology; Imaging, Three-Dimensional / methods; Liver / anatomy & histology; Marmota; Mice; Pulmonary Veins / anatomy & histology
TL;DR: Three‐dimensional volumes of the crown of an oat plant showing internal responses to a freezing treatment, a sample of a hepatocellular carcinoma from a woodchuck liver that had been heat‐treated with computer‐guided radiofrequency ablation to induce necrosis in the central portion of the tumour, and several features of a samples of mouse lung are presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

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