Works (6)

Updated: July 5th, 2023 15:29

2022 article

Genomic map of candidate human imprint control regions: the imprintome

Jima, D. D., Skaar, D. A., Planchart, A., Motsinger-Reif, A., Cevik, S. E., Park, S. S., … Hoyo, C. (2022, June 25). EPIGENETICS, Vol. 6.

By: D. Jima n, D. Skaar n, A. Planchart n, A. Motsinger-Reif n, S. Cevik n, S. Park n, M. Cowley n, F. Wright n ...

author keywords: Epigenetics; genomic imprinting; foetal origins; whole genome; methylation; imprint control regions
MeSH headings : Adult; Humans; Genomic Imprinting; DNA Methylation; Chromosome Mapping; Alleles; Genomics
TL;DR: This draft of the human imprintome will allow for the systematic determination of the role of early-acquired imprinting dysregulation in the pathogenesis of human diseases and developmental and behavioural disorders. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 11, 2022

2020 journal article

Associations between maternal obesity, gestational cytokine levels and child obesity in the NEST cohort

PEDIATRIC OBESITY, 16(7).

By: R. Maguire n, J. House n, D. Lloyd n, H. Skinner n, T. Allen*, A. Raffi n, D. Skaar n, S. Park n ...

Contributors: R. Maguire n, J. House n, D. Lloyd n, H. Skinner n, T. Allen*, A. Raffi n, D. Skaar n, S. Park n ...

author keywords: cytokines; maternal obesity; childhood obesity
MeSH headings : Black or African American; Body Mass Index; Child; Child, Preschool; Cohort Studies; Cytokines / blood; Female; Humans; Obesity, Maternal / epidemiology; Pediatric Obesity / epidemiology; Pregnancy; White People
TL;DR: Although maternal systemic inflammation is hypothesized to link maternal pre‐pregnancy obesity to offspring metabolic dysfunction, patient empirical data are limited. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 19, 2021

2019 journal article

Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study

EPIGENETICS, 14(4), 325–340.

By: C. Martin*, D. Jima n, G. Sharp*, L. McCullough*, S. Park n, K. Gowdy*, D. Skaar n, M. Cowley n ...

author keywords: DNA methylation; epigenome-wide association study; maternal obesity; offspring body mass index; offspring blood pressure; cardiometabolic health; ALSPAC; NEST
MeSH headings : Adult; Blood Pressure; Cardiovascular Diseases / epidemiology; Cardiovascular Diseases / genetics; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Genome-Wide Association Study; Humans; Infant, Newborn / blood; Infant, Newborn / growth & development; Male; Membrane Transport Proteins / genetics; Metabolic Syndrome / epidemiology; Metabolic Syndrome / genetics; Obesity / epidemiology; Obesity / genetics
TL;DR: Findings suggest sex-specific effects at CpG sites of the TAPBP gene were associated with BMI z-score and systolic BP percentile in female and syStolic and diastolicBP percentile in male offspring, which, if causal, may explain observed sex- specific effects of maternal obesity. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 29, 2019

2018 article

EPIGENOMICS AND HUMAN OBESITY

EPIGENETICS IN HUMAN DISEASE, 2ND EDITION, Vol. 6, pp. 409–426.

By: C. Hoyo n, D. Skaar n, S. Park n & P. Sorrow n

TL;DR: This chapter summarizes human data on CpG methylation, the most studied epigenetic mechanism in humans, in the context of causal inference, in adults and children, and concludes with a call for sex- and ethnic-specific data, together with data demonstrating that obesity-associated DNA methylation marks identified precede obesity. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 22, 2019

2018 journal article

Effects of cadmium exposure on DNA methylation at imprinting control regions and genome-wide in mothers and newborn children

Environmental Health Perspectives, 126(3).

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

An Extended n-h bond, driven by a conserved second-order interaction, orients the flavin n5 orbital in cholesterol oxidase

Scientific Reports, 7.

By: E. Golden, L. Yu, F. Meilleur, M. Blakeley, A. Duff, A. Karton, A. Vrielink

Source: NC State University Libraries
Added: August 6, 2018

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