Sarah S. Park

Works (6)

Updated: July 5th, 2023 15:29

2022 article

Genomic map of candidate human imprint control regions: the imprintome

Jima, D. D., Skaar, D. A., Planchart, A., Motsinger-Reif, A., Cevik, S. E., Park, S. S., … Hoyo, C. (2022, June 25). EPIGENETICS, Vol. 6.

By: D. Jima n, D. Skaar n , A. Planchart n , A. Motsinger-Reif n, S. Cevik  n, S. Park n, M. Cowley n , F. Wright n ...

author keywords: Epigenetics; genomic imprinting; foetal origins; whole genome; methylation; imprint control regions
MeSH headings : Adult; Humans; Genomic Imprinting; DNA Methylation; Chromosome Mapping; Alleles; Genomics
TL;DR: This draft of the human imprintome will allow for the systematic determination of the role of early-acquired imprinting dysregulation in the pathogenesis of human diseases and developmental and behavioural disorders. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 11, 2022

2020 journal article

Associations between maternal obesity, gestational cytokine levels and child obesity in the NEST cohort

PEDIATRIC OBESITY, 16(7).

By: R. Maguire n, J. House n , D. Lloyd n, H. Skinner n, T. Allen *, A. Raffi n, D. Skaar n , S. Park n ...

Contributors: R. Maguire n, J. House n , D. Lloyd n, H. Skinner n, T. Allen *, A. Raffi n, D. Skaar n , S. Park n ...

author keywords: cytokines; maternal obesity; childhood obesity
MeSH headings : Black or African American; Body Mass Index; Child; Child, Preschool; Cohort Studies; Cytokines / blood; Female; Humans; Obesity, Maternal / epidemiology; Pediatric Obesity / epidemiology; Pregnancy; White People
TL;DR: Although maternal systemic inflammation is hypothesized to link maternal pre‐pregnancy obesity to offspring metabolic dysfunction, patient empirical data are limited. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 19, 2021

2019 journal article

Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study

EPIGENETICS, 14(4), 325–340.

By: C. Martin *, D. Jima n, G. Sharp *, L. McCullough *, S. Park n, K. Gowdy *, D. Skaar n , M. Cowley n  ...

author keywords: DNA methylation; epigenome-wide association study; maternal obesity; offspring body mass index; offspring blood pressure; cardiometabolic health; ALSPAC; NEST
MeSH headings : Adult; Blood Pressure; Cardiovascular Diseases / epidemiology; Cardiovascular Diseases / genetics; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Genome-Wide Association Study; Humans; Infant, Newborn / blood; Infant, Newborn / growth & development; Male; Membrane Transport Proteins / genetics; Metabolic Syndrome / epidemiology; Metabolic Syndrome / genetics; Obesity / epidemiology; Obesity / genetics
TL;DR: Findings suggest sex-specific effects at CpG sites of the TAPBP gene were associated with BMI z-score and systolic BP percentile in female and syStolic and diastolicBP percentile in male offspring, which, if causal, may explain observed sex- specific effects of maternal obesity. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 29, 2019

2018 article

EPIGENOMICS AND HUMAN OBESITY

EPIGENETICS IN HUMAN DISEASE, 2ND EDITION, Vol. 6, pp. 409–426.

By: C. Hoyo n , D. Skaar n , S. Park n & P. Sorrow n

TL;DR: This chapter summarizes human data on CpG methylation, the most studied epigenetic mechanism in humans, in the context of causal inference, in adults and children, and concludes with a call for sex- and ethnic-specific data, together with data demonstrating that obesity-associated DNA methylation marks identified precede obesity. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: April 22, 2019

2018 journal article

Effects of cadmium exposure on DNA methylation at imprinting control regions and genome-wide in mothers and newborn children

Environmental Health Perspectives, 126(3).

By: M. Cowley , D. Skaar , D. Jima, R. Maguire, K. Hudson, S. Park, P. Sorrow, C. Hoyo 

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

An Extended n-h bond, driven by a conserved second-order interaction, orients the flavin n5 orbital in cholesterol oxidase

Scientific Reports, 7.

By: E. Golden, L. Yu, F. Meilleur, M. Blakeley, A. Duff, A. Karton, A. Vrielink

Source: NC State University Libraries
Added: August 6, 2018

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