Sydney Stine

College of Engineering

Works (1)

Updated: July 5th, 2023 14:27

2020 journal article

Dual-Affinity Ratiometric Quenching (DARQ) Assay for the Quantification of Therapeutic Antibodies in CHO-S Cell Culture Fluids

ANALYTICAL CHEMISTRY, 92(24), 16274–16283.

By: B. Turner n, K. Kilgour n, S. Stine n, M. Daniele n & S. Menegatti n 

MeSH headings : Animals; Antibodies, Monoclonal / analysis; Antibodies, Monoclonal / immunology; Antibodies, Monoclonal / therapeutic use; Antigens / immunology; CHO Cells; Cricetulus; Spectrometry, Fluorescence / methods
TL;DR: A novel dual-affinity ratiometric quenching (DARQ) assay, which combines selective biorecognition andQuenching of fluorescence signals for rapid and sensitive quantification of therapeutic monoclonal antibodies (mAbs). (via Semantic Scholar)
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Added: January 11, 2021

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