Sydney Stine
College of Engineering
Works (1)
Updated: July 5th, 2023 14:27
2020 journal article
Dual-Affinity Ratiometric Quenching (DARQ) Assay for the Quantification of Therapeutic Antibodies in CHO-S Cell Culture Fluids
ANALYTICAL CHEMISTRY, 92(24), 16274–16283.
MeSH headings : Animals; Antibodies, Monoclonal / analysis; Antibodies, Monoclonal / immunology; Antibodies, Monoclonal / therapeutic use; Antigens / immunology; CHO Cells; Cricetulus; Spectrometry, Fluorescence / methods
TL;DR:
A novel dual-affinity ratiometric quenching (DARQ) assay, which combines selective biorecognition andQuenching of fluorescence signals for rapid and sensitive quantification of therapeutic monoclonal antibodies (mAbs).
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Added: January 11, 2021