Works (7)
Updated: July 5th, 2023 15:43
2015 journal article
Generation and characterization of nucleic acid aptamers targeting the capsid P domain of a human norovirus GII.4 strain
JOURNAL OF BIOTECHNOLOGY, 209, 41–49.
author keywords: SELEX; Aptamer; Norovirus; Molecular detection; Viral diagnostics
MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Capsid Proteins / genetics; Capsid Proteins / metabolism; Feces / virology; Humans; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; SELEX Aptamer Technique / methods; Sensitivity and Specificity
TL;DR:
This is the first demonstration of human NoV P domain protein as a functional target for the selection of nucleic acid aptamers that specifically bind and broadly recognize diversehuman NoV strains.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Ligularia fischeri Extract Protects Against Oxidative-Stress-Induced Neurotoxicity in Mice and PC12 Cells
JOURNAL OF MEDICINAL FOOD, 17(11), 1222–1231.
author keywords: Ligularia fischeri; amyloid beta peptide; 3-O-caffeoylquinic acid; oxidative stress
MeSH headings : Alzheimer Disease / metabolism; Alzheimer Disease / prevention & control; Amyloid beta-Peptides / metabolism; Amyloid beta-Peptides / toxicity; Animals; Antioxidants / pharmacology; Antioxidants / therapeutic use; Asteraceae / chemistry; Avoidance Learning / drug effects; Brain / drug effects; Chlorogenic Acid / pharmacology; Chlorogenic Acid / therapeutic use; Cognition Disorders / chemically induced; Cognition Disorders / genetics; Cognition Disorders / prevention & control; DNA Fragmentation / drug effects; Hydrogen Peroxide / metabolism; Hydrogen Peroxide / toxicity; Learning Disabilities / chemically induced; Learning Disabilities / prevention & control; Lipid Peroxidation / drug effects; Male; Memory / drug effects; Memory Disorders / chemically induced; Memory Disorders / prevention & control; Mice, Inbred ICR; Neuroprotective Agents / pharmacology; Neuroprotective Agents / therapeutic use; Neurotoxicity Syndromes / genetics; Neurotoxicity Syndromes / prevention & control; Oxidative Stress / drug effects; PC12 Cells; Phytotherapy; Plant Extracts / pharmacology; Plant Extracts / therapeutic use; Rats
TL;DR:
Results suggest that L. fischeri extract could be protective against Aβ-induced neurotoxicity, possibly due to the antioxidative capacity of its constituent, 3-O-caffeoylquinic acid.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Molecular methods used to estimate thermal inactivation of a prototype human norovirus: More heat resistant than previously believed?
FOOD MICROBIOLOGY, 41, 91–95.
author keywords: Human norovirus; Thermal inactivation; Heat resistance
MeSH headings : Azides / chemistry; Caliciviridae Infections / virology; Hot Temperature; Humans; Norovirus / chemistry; Norovirus / genetics; Norovirus / isolation & purification; Norovirus / physiology; Polymerase Chain Reaction; Propidium / analogs & derivatives; Propidium / chemistry; RNA, Viral / chemistry; RNA, Viral / genetics; Virus Inactivation
TL;DR:
Electron microscopy data applied to heat-treated virus-like particles supported this relatively high degree of thermal resistance and suggest that SMV is more heat resistant than common cultivable HuNoV surrogates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Selection and characterization of DNA aptamers specific for Listeria species
ANALYTICAL BIOCHEMISTRY, 459, 39–45.
author keywords: Listeria monocytogenes; Listeria spp.; Aptamer; SELEX; Pathogen detection
MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / genetics; Aptamers, Nucleotide / metabolism; Base Sequence; Binding Sites; Cell Survival; Listeria monocytogenes / cytology; Listeria monocytogenes / metabolism; SELEX Aptamer Technique / methods; Species Specificity; Substrate Specificity
TL;DR:
This is the first study in which SELEX targeted bacterial cells at different growth phases and found that aptamers that bind to different cell surface moieties could increase the analytical sensitivity of future capture and detection assays.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Selection, Characterization and Application of Nucleic Acid Aptamers for the Capture and Detection of Human Norovirus Strains
PLOS ONE, 9(9).
MeSH headings : Aptamers, Nucleotide / chemistry; Aptamers, Nucleotide / metabolism; Bacteriological Techniques / methods; DNA, Viral / chemistry; DNA, Viral / metabolism; Feces / virology; Food Microbiology; Humans; Lettuce / virology; Molecular Structure; Norovirus / classification; Norovirus / genetics; Norovirus / isolation & purification; Sensitivity and Specificity
TL;DR:
These ssDNA aptamer candidates show promise as broadly reactive reagents for use in HuNoV capture and detection assays in various sample types.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Development and evaluation of aptamer magnetic capture assay in conjunction with real-time PCR for detection of Campylobacter jejuni
LWT-FOOD SCIENCE AND TECHNOLOGY, 56(2), 256–260.
author keywords: Aptamer; Aptamer magnetic capture; Campylobacter jejuni; Real-time PCR; Pathogen detection
TL;DR:
A prototype method for the concentration and detection of Campylobacter jejuni was developed using a previously reported biotinylated DNA aptamer in conjunction with qPCR, and nucleic acid aptamers are promising alternatives to antibodies for magnetic bead-based capture followed byqPCR detection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Nucleic acid aptamers for capture and detection of Listeria spp
JOURNAL OF BIOTECHNOLOGY, 167(4), 454–461.
author keywords: Listeria monocytogenes; Listeria spp; DNA aptamer; Aptamer magnetic capture; Immunomagnetic separation; Real-time PCR
MeSH headings : Aptamers, Nucleotide / chemical synthesis; Aptamers, Nucleotide / economics; Bacteriological Techniques / methods; Base Sequence; Biotinylation; Flow Cytometry; Listeria monocytogenes / isolation & purification; Molecular Sequence Data; Real-Time Polymerase Chain Reaction
TL;DR:
Biotinylated ssDNA aptamers are promising ligands for food-borne pathogen concentration prior to detection using molecular methods and showed similar binding affinity for other members of the Listeria genus and lowbinding affinity for non-Listeria species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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