Works (33)

Updated: July 8th, 2023 21:13

2022 article

IgD(+) age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

Kugler-Umana, O., Zhang, W., Kuang, Y., Liang, J., Castonguay, C. H., Tonkonogy, S. L., … Swain, S. L. (2022, September 2). AGING CELL.

co-author countries: United States of America 🇺🇸
author keywords: adaptive immunity; age-associated B cells; aging; influenza; TLR signals
MeSH headings : Animals; Humans; Mice; Antibodies, Viral; Immunoglobulin D; Immunoglobulin G; Immunoglobulin M; Influenza Vaccines; Influenza, Human; Toll-Like Receptor 7; Toll-Like Receptor 9; Vaccines, Inactivated; B-Lymphocytes; T-Lymphocytes
Source: Web Of Science
Added: September 12, 2022

2022 journal article

Microbiome Shapes the T Cell Receptor Repertoire among CD4+CD8+ Thymocytes

BIOMEDICINES, 10(12).

By: S. Surman*, J. Crawford*, P. Dash*, S. Tonkonogy n, P. Thomas* & J. Hurwitz*

co-author countries: United States of America 🇺🇸
author keywords: E; coli; germ-free; gnotobiotic; T cell receptor repertoire; thymus; CD4+CD8+ T cell
Source: Web Of Science
Added: January 17, 2023

2019 journal article

Murine Adherent and Invasive E. coli Induces Chronic Inflammation and Immune Responses in the Small and Large Intestines of Monoassociated IL-10(-/-) Mice Independent of Long Polar Fimbriae Adhesin

INFLAMMATORY BOWEL DISEASES, 25(5), 875–885.

By: J. Schmitz n, S. Tonkonogy n, B. Dogan*, A. Leblond n, K. Whitehead n, S. Kim n, K. Simpson*, R. Sartor n

co-author countries: United States of America 🇺🇸
author keywords: ileitis; colitis; cytokines; T cells; adherent invasive E. coli
MeSH headings : Animals; Bacterial Adhesion; Escherichia coli / immunology; Escherichia coli Infections / immunology; Escherichia coli Infections / metabolism; Escherichia coli Infections / microbiology; Escherichia coli Infections / pathology; Escherichia coli Proteins / metabolism; Fimbriae Proteins / metabolism; Fimbriae, Bacterial / immunology; Fimbriae, Bacterial / pathology; Inflammation / etiology; Inflammation / metabolism; Inflammation / pathology; Interleukin-10 / physiology; Intestine, Large / immunology; Intestine, Large / metabolism; Intestine, Large / microbiology; Intestine, Large / pathology; Intestine, Small / immunology; Intestine, Small / metabolism; Intestine, Small / microbiology; Intestine, Small / pathology; Mice; Mice, Knockout
Source: Web Of Science
Added: July 15, 2019

2016 journal article

Transient activation of mucosal effector immune responses by resident intestinal bacteria in normal hosts is regulated by interleukin-10 signalling

IMMUNOLOGY, 148(3), 304–314.

By: C. Wu*, R. Sartor*, K. Huang* & S. Tonkonogy n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: germ-free mice; interleukin-10; resident bacteria
MeSH headings : Animals; Antigens, Bacterial / immunology; B-Lymphocytes / immunology; Cells, Cultured; Colitis / etiology; Colitis / immunology; Disease Models, Animal; Escherichia coli / immunology; Escherichia coli Infections / complications; Escherichia coli Infections / immunology; Immunity, Mucosal; Interferon-gamma / metabolism; Interleukin-10 / genetics; Interleukin-10 / metabolism; Intestines / immunology; Intestines / microbiology; Lymphocyte Activation; Mice; Mice, 129 Strain; Mice, Knockout; Signal Transduction; Th1 Cells / immunology
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Molecular detection of bacterial contamination in gnotobiotic rodent units

Gut Microbes, 4(5), 361–370.

By: C. Packey*, M. Shanahan*, S. Manick*, M. Bower*, M. Ellermann*, S. Tonkonogy n, I. Carroll*, R. Sartor*

co-author countries: United States of America 🇺🇸
MeSH headings : Animal Feed / analysis; Animal Feed / microbiology; Animals; Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; DNA, Bacterial / genetics; Feces / microbiology; Germ-Free Life; Mice / microbiology; Polymerase Chain Reaction / methods; RNA, Ribosomal, 16S / genetics; Random Amplified Polymorphic DNA Technique / methods
Source: Crossref
Added: July 20, 2019

2011 journal article

Antigen-Presenting Cell Production of IL-10 Inhibits T-Helper 1 and 17 Cell Responses and Suppresses Colitis in Mice

GASTROENTEROLOGY, 141(2), 653–U764.

By: B. Liu*, S. Tonkonogy n & R. Sartor*

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Mouse Model; Inflammatory Bowel Disease; Immune Response; Microbiota
MeSH headings : Adaptive Immunity; Animals; Antigen-Presenting Cells / drug effects; Antigen-Presenting Cells / metabolism; Antigens, Bacterial / immunology; CD11b Antigen / metabolism; CD4-Positive T-Lymphocytes / metabolism; Cells, Cultured; Colitis / immunology; DNA-Binding Proteins / deficiency; DNA-Binding Proteins / genetics; Forkhead Transcription Factors / metabolism; Germ-Free Life; Immunity, Innate; Interferon-gamma / metabolism; Interleukin-10 / deficiency; Interleukin-10 / genetics; Interleukin-10 / immunology; Interleukin-10 / metabolism; Interleukin-10 / pharmacology; Interleukin-12 / metabolism; Interleukin-17 / metabolism; Mice; Mice, Knockout; RNA, Messenger / metabolism; Signal Transduction; Smad Proteins; T-Box Domain Proteins / metabolism; T-Lymphocytes, Regulatory / cytology; Th1 Cells / immunology; Th17 Cells / immunology; Transforming Growth Factor beta / metabolism; Tretinoin / physiology
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation

GASTROENTEROLOGY, 141(3), 959–971.

By: N. Steck*, M. Hoffmann*, I. Sava*, S. Kim*, H. Hahne*, S. Tonkonogy n, K. Mair*, D. Krueger* ...

co-author countries: Germany 🇩🇪 Ireland 🇮🇪 United States of America 🇺🇸
author keywords: IBD; Bacteria-Host Interactions; Bacterial Protease; Intestinal Barrier Function
MeSH headings : Animals; CD4-Positive T-Lymphocytes / physiology; Cadherins / metabolism; Cell Membrane Permeability / physiology; Colitis / etiology; Colitis / metabolism; Colitis / physiopathology; Disease Models, Animal; Enterococcus faecalis / metabolism; Gelatinases / metabolism; Gram-Positive Bacterial Infections / complications; Gram-Positive Bacterial Infections / metabolism; Gram-Positive Bacterial Infections / physiopathology; Interleukin-10 / genetics; Interleukin-10 / metabolism; Intestinal Mucosa / cytology; Intestinal Mucosa / metabolism; Metalloproteases / metabolism; Mice; Mice, Knockout; Mice, Mutant Strains; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Adaptation in a Mouse Colony Monoassociated with Escherichia coli K-12 for More than 1,000 Days

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(14), 4655–4663.

By: S. Lee, A. Wyse, A. Lesher, M. Everett, L. Lou, Z. Holzknecht, J. Whitesides*, P. Spears n ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Escherichia coli K12 / genetics; Escherichia coli K12 / growth & development; Gastrointestinal Tract / microbiology; Longitudinal Studies; Mice; Restriction Mapping
Source: Web Of Science
Added: August 6, 2018

2009 conference paper

Bifidobacterium animalis causes extensive duodenitis and mild colonic inflammation in monoassociated interleukin-lO-deficient mice

Inflammatory Bowel Diseases, 15(7), 1022–1031.

By: J. Moran*, J. Walter*, G. Tannock*, S. Tonkonogy n & R. Sartor*

co-author countries: New Zealand 🇳🇿 United States of America 🇺🇸
MeSH headings : Animals; Antigens, Bacterial / immunology; Bifidobacteriales Infections / complications; Bifidobacteriales Infections / immunology; Bifidobacteriales Infections / pathology; Bifidobacterium / immunology; Colitis / immunology; Colitis / microbiology; Colitis / pathology; Dendritic Cells / immunology; Dendritic Cells / microbiology; Dendritic Cells / pathology; Disease Models, Animal; Duodenitis / immunology; Duodenitis / microbiology; Duodenitis / pathology; Epitopes / immunology; Interleukin-10 / genetics; Interleukin-10 / immunology; Interleukin-12 / immunology; Interleukin-23 / immunology; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Severity of Illness Index; Th1 Cells / immunology; Th1 Cells / microbiology; Th1 Cells / pathology
Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Endogenous antigen presenting cell-derived IL-10 inhibits T lymphocyte responses to commensal enteric bacteria

IMMUNOLOGY LETTERS, 123(1), 77–87.

By: C. Albright*, R. Sartor* & S. Tonkonogy n

co-author countries: United States of America 🇺🇸
author keywords: Cytokine regulation; Antigen presenting cells; IL-10 deficient mice
MeSH headings : Animals; Antigen-Presenting Cells / drug effects; Antigen-Presenting Cells / immunology; CD4-Positive T-Lymphocytes / drug effects; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / microbiology; Coculture Techniques; Colitis / immunology; Colitis / microbiology; Colon / immunology; Colon / microbiology; Enterobacteriaceae / immunology; Interferon-gamma / biosynthesis; Interferon-gamma / immunology; Interleukin-10 / genetics; Interleukin-10 / immunology; Interleukin-10 / pharmacology; Interleukin-12 / biosynthesis; Interleukin-12 / immunology; Interleukin-17 / biosynthesis; Interleukin-17 / immunology; Interleukin-23 / biosynthesis; Interleukin-23 / immunology; Mice; Mice, Knockout
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Aberrant Innate Immune Responses in TLR-ligand Activated HLA-B27 Transgenic Rat Cells

INFLAMMATORY BOWEL DISEASES, 14(10), 1358–1365.

By: B. Qian, S. Tonkonogy* & R. Sartor

author keywords: HLA-B27 transgenic rats; bacterial adjuvants; Toll-like receptors; innate immune responses; splenocytes
MeSH headings : Animals; Bacteria / immunology; Colitis / genetics; Colitis / immunology; Flow Cytometry; Gene Expression; Germ-Free Life / immunology; HLA-B27 Antigen / genetics; Humans; Immunity, Innate; Interleukin-10 / metabolism; Rats; Rats, Inbred F344; Rats, Transgenic; Specific Pathogen-Free Organisms / immunology; Spleen / cytology; T-Lymphocyte Subsets / immunology; Toll-Like Receptor 2 / metabolism; Toll-Like Receptor 4 / metabolism; Toll-Like Receptors / genetics; Toll-Like Receptors / metabolism; Tumor Necrosis Factor-alpha / metabolism
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Reduced responsiveness of HLA-B27 transgenic rat cells to TGF-beta and IL-10-mediated regulation of IFN-gamma production

INFLAMMATORY BOWEL DISEASES, 14(7), 921–930.

By: B. Qian*, S. Tonkonogy n & R. Sartor*

co-author countries: United States of America 🇺🇸
author keywords: HLA-B27 transgenic rats; cytokines; defective regulation
MeSH headings : Animals; Animals, Genetically Modified; Bacteria / immunology; Blotting, Western; Cells, Cultured; Colitis / physiopathology; Down-Regulation; Enzyme-Linked Immunosorbent Assay; HLA-B27 Antigen / genetics; Interferon-gamma / biosynthesis; Interleukin-10 / biosynthesis; Interleukin-10 / pharmacology; Interleukin-12 / pharmacology; Lymph Nodes / drug effects; Mesentery; Rats; Specific Pathogen-Free Organisms; Transforming Growth Factor beta / pharmacology
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Bacterial symbionts induce a FUT2-dependent fucosylated niche on colonic epithelium via ERK and JNK signaling

American Journal of Physiology-Gastrointestinal and Liver Physiology, 293(4), G780–G787.

By: D. Meng, D. Newburg*, C. Young*, A. Baker*, S. Tonkonogy*, R. Sartor*, W. Walker*, N. Nanthakumar*

co-author countries: United States of America 🇺🇸
author keywords: bacterial colonization; fucosylation
MeSH headings : Animals; Colon / microbiology; Extracellular Signal-Regulated MAP Kinases / physiology; Fucosyltransferases / physiology; Germ-Free Life; Intestinal Mucosa / microbiology; JNK Mitogen-Activated Protein Kinases / physiology; Mice; Signal Transduction / physiology; Symbiosis
Source: Crossref
Added: July 20, 2019

2007 journal article

CD4(+) T lymphocytes mediate colitis in HLA-B27 transgenic rats monoassociated with nonpathogenic Bacteroides vulgatus

INFLAMMATORY BOWEL DISEASES, 13(3), 317–324.

By: F. Hoentjen*, S. Tonkonogy n, B. Qian*, B. Liu*, L. Dieleman* & R. Sartor*

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
author keywords: Bacteroides vulgatus; cytokines; HLA-B27; transgenic rats
MeSH headings : Animals; Bacteroides; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / microbiology; Colitis / immunology; HLA-B27 Antigen / immunology; Interferon-gamma / metabolism; Interleukin-10 / metabolism; Organisms, Genetically Modified; Rats; Rats, Nude
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Dual-association of gnotobiotic IL-10-/- mice vith 2 nonpathogenic commensal bacteria induces aggressive pancolitis

INFLAMMATORY BOWEL DISEASES, 13(12), 1457–1466.

By: S. Kim*, S. Tonkonogy n, T. Karrasch*, C. Jobin* & R. Sartor*

co-author countries: United States of America 🇺🇸
author keywords: gnotobiotic IL-10-/- mice; pancolitis; commensal bacteria
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; Colitis / immunology; Colitis / microbiology; Colon / chemistry; Colon / pathology; Colony Count, Microbial; Duodenitis / immunology; Duodenitis / microbiology; Enterococcus faecalis / growth & development; Escherichia coli / growth & development; Escherichia coli Infections / immunology; Escherichia coli Infections / microbiology; Germ-Free Life; Gram-Positive Bacterial Infections / immunology; Gram-Positive Bacterial Infections / microbiology; Interferon-gamma / analysis; Interleukin-10 / deficiency; Interleukin-12 / genetics; Interleukin-23 / genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B / biosynthesis; Up-Regulation
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Adoptive transfer of nontransgenic mesenteric lymph node cells induces colitis in athymic HLA-B27 transgenic nude rats

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 143(3), 474–483.

By: F. Hoentjen*, S. Tonkonogy n, B. Liu*, R. Sartor*, J. Taurog* & L. Dieleman*

co-author countries: United States of America 🇺🇸
author keywords: T cells; HLA-B27; nude; transgenic rats; commensal bacteria
MeSH headings : Adoptive Transfer; Animals; Animals, Genetically Modified; Bacteria / immunology; Cecum / immunology; Cecum / microbiology; Cell Extracts / immunology; Cell Proliferation; Colitis / etiology; Colitis / immunology; Colitis / microbiology; Colitis / pathology; Cytokines / biosynthesis; Disease Models, Animal; HLA-B27 Antigen / genetics; HLA-B27 Antigen / metabolism; Interleukin-1 / immunology; Lymphocyte Activation; Lymphocyte Transfusion; Mesentery; Peroxidase / metabolism; Rats; Rats, Inbred F344; Rats, Nude
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Luminal bacterial antigen-specific CD4(+) T-cell responses in HLA-B27 transgenic rats with chronic colitis are mediated by both major histocompatibility class II and HLA-B27 molecules

IMMUNOLOGY, 117(3), 319–328.

By: B. Qian*, S. Tonkonogy n & R. Sartor*

co-author countries: United States of America 🇺🇸
author keywords: CD4(+) T-cell responses; HLA-B27; MHC class II; enteric bacterial antigens; transgenic rats
MeSH headings : Animals; Animals, Genetically Modified; Antigen-Presenting Cells / immunology; Antigens, Bacterial / immunology; CD4-Positive T-Lymphocytes / immunology; Cells, Cultured; Chronic Disease; Coculture Techniques; Colitis / immunology; Enterobacteriaceae / immunology; Female; HLA-B27 Antigen / genetics; HLA-B27 Antigen / immunology; Histocompatibility Antigens Class II / immunology; Interferon-gamma / biosynthesis; Lymph Nodes / immunology; Lymphocyte Activation / immunology; Male; Rats
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Dysregulated luminal bacterial antigen-specific T-cell responses and antigen-presenting cell function in HLA-B27 transgenic rats with chronic colitis

IMMUNOLOGY, 116(1), 112–121.

By: B. Qian*, S. Tonkonogy*, F. Hoentjen*, L. Dieleman* & R. Sartor n

co-author countries: United States of America 🇺🇸
author keywords: antigen-presenting cells; CD4(+) T lymphocytes; enteric bacterial antigens; HLA-B27 transgenic rats
MeSH headings : Animals; Animals, Genetically Modified; Antigen-Presenting Cells / immunology; Antigens, Bacterial / immunology; CD4-Positive T-Lymphocytes / immunology; Cecum / immunology; Cecum / microbiology; Cells, Cultured; Chronic Disease; Coculture Techniques; Colitis / immunology; Colitis / microbiology; Female; Germ-Free Life; HLA-B27 Antigen / analysis; HLA-B27 Antigen / genetics; Interferon-gamma / biosynthesis; Interferon-gamma / immunology; Interleukin-10 / biosynthesis; Interleukin-10 / immunology; Lymph Nodes / immunology; Male; Rats; Rats, Inbred F344; T-Lymphocyte Subsets / immunology
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria

GASTROENTEROLOGY, 128(4), 891–906.

By: S. Kim*, S. Tonkonogy n, C. Albright*, J. Tsang*, E. Balish*, J. Braun*, M. Huycke*, R. Sartor*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Antibody Formation; Antigens, Bacterial / immunology; CD4-Positive T-Lymphocytes / immunology; Cecal Diseases / microbiology; Cecal Diseases / pathology; Chronic Disease; Colitis / microbiology; Colitis / pathology; Colony Count, Microbial; Cytokines / biosynthesis; Disease Progression; Enterococcus faecalis / immunology; Enterocolitis / genetics; Enterocolitis / metabolism; Enterocolitis / microbiology; Enterocolitis / pathology; Escherichia coli / immunology; Escherichia coli Infections / microbiology; Gastroenteritis / microbiology; Gastroenteritis / pathology; Gram-Positive Bacterial Infections / microbiology; Interleukin-10 / deficiency; Intestinal Mucosa / metabolism; Lymph Nodes / immunology; Mice; Mice, Knockout; Phenotype
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Reduced ratio of protective versus proinflammatory cytokine responses to commensal bacteria in HLA-B27 transgenic rats

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 136(1), 30–39.

By: L. Dieleman*, F. Hoentjen*, B. Qian*, D. Sprengers*, E. Tjwa*, M. Torres*, C. Torrice*, R. Sartor*, S. Tonkonogy n

co-author countries: United States of America 🇺🇸
author keywords: cytokines; HLA-B27; transgenic rats; commensal bacteria
MeSH headings : Animals; Animals, Genetically Modified; Antigen-Presenting Cells / immunology; B-Lymphocytes / immunology; Bacteria / immunology; Cecum / microbiology; Cecum / pathology; Cells, Cultured; Colitis / genetics; Colitis / immunology; Colitis / microbiology; Cytokines / biosynthesis; Cytokines / genetics; Gene Expression; Germ-Free Life; HLA-B27 Antigen / genetics; Lymph Nodes / immunology; RNA, Messenger / genetics; Rats; Rats, Inbred F344; T-Lymphocyte Subsets / immunology
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Lactobacillus plantarum 299V in the treatment and prevention of spontaneous colitis in interleukin-10-deficient mice

INFLAMMATORY BOWEL DISEASES, 8(2), 71–80.

By: M. Schultz*, C. Veltkamp, L. Dieleman, W. Grenther*, P. Wyrick n, S. Tonkonogy*, R. Sartor*

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: probiotics; experimental colitis; interleukin-10 knockout mice
MeSH headings : Administration, Oral; Animals; Colitis / immunology; Colitis / microbiology; Colitis / pathology; Colitis / prevention & control; Disease Models, Animal; Interleukin-10 / deficiency; Interleukin-10 / genetics; Lactobacillus / classification; Lactobacillus / physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Probiotics / administration & dosage; Probiotics / therapeutic use; Specific Pathogen-Free Organisms
Source: Web Of Science
Added: August 6, 2018

2001 article

Continuous stimulation by normal luminal bacteria is essential for the development and perpetuation of colitis in Tg is an element of 26 mice

Veltkamp, C., Tonkonogy, S. L., De Jong, Y. P., Albright, C., Grenther, W. B., Balish, E., … Sartor, R. B. (2001, March). GASTROENTEROLOGY, Vol. 120, pp. 900–913.

By: C. Veltkamp*, S. Tonkonogy n, Y. De Jong*, C. Albright*, W. Grenther n, E. Balish*, C. Terhorst*, R. Sartor*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Bacterial Physiological Phenomena; Bone Marrow Transplantation; Colitis / microbiology; Colitis / pathology; Colitis / prevention & control; Colon / microbiology; Colon / pathology; Germ-Free Life; Immunocompetence / physiology; Intestinal Mucosa / cytology; Lymph Nodes / cytology; Mesentery; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phenotype; T-Lymphocytes / physiology; T-Lymphocytes / transplantation; Wasting Syndrome / prevention & control
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Disrupted B-lymphocyte development and survival in interleukin-2-deficient mice

IMMUNOLOGY, 104(2), 127–134.

By: M. Schultz*, S. Clarke*, L. Arnold*, R. Sartor* & S. Tonkonogy n

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Animals; Ascitic Fluid / immunology; B-Lymphocytes / immunology; B-Lymphocytes / pathology; Bone Marrow Cells / immunology; Cell Differentiation / immunology; Cell Survival / immunology; Flow Cytometry; Hematopoietic Stem Cells / immunology; Immunoglobulin G / biosynthesis; Immunoglobulin G / blood; Interleukin-2 / deficiency; Interleukin-2 / immunology; Mice; Mice, Inbred C57BL; Spleen / immunology; T-Lymphocyte Subsets / immunology
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Helicobacter hepaticus does not induce or potentiate colitis in interleukin-10-deficient mice

INFECTION AND IMMUNITY, 68(9), 5107–5113.

By: L. Dieleman*, A. Arends*, S. Tonkonogy n, M. Goerres*, D. Craft*, W. Grenther n, R. Sellon n, E. Balish*, R. Sartor*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; Colitis / etiology; Germ-Free Life; Helicobacter / pathogenicity; Interleukin-10 / deficiency; Interleukin-10 / physiology; Lymphocyte Activation; Mice; Mice, Inbred C57BL
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Natural killer cell-dependent immunoglobulin G2a anti-bovine serum albumin (BSA) response elicited by high molecular weight dextran-BSA conjugates associated with dextran-mediated macrophage-natural killer cell interaction

IMMUNOLOGY, 101(4), 474–483.

By: C. Ediriwickrema n, S. Tonkonogy n & B. Hammerberg n

co-author countries: United States of America 🇺🇸
MeSH headings : Adjuvants, Immunologic; Animals; Cell Communication / immunology; Cell Culture Techniques; Dextrans / immunology; Dose-Response Relationship, Immunologic; Immunization / methods; Immunoglobulin G / biosynthesis; Interferon-gamma / biosynthesis; Interleukin-12 / biosynthesis; Killer Cells, Natural / immunology; Macrophages / immunology; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Serum Albumin, Bovine / immunology; Spleen / immunology
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Quantitation of thymic and bursal lymphocytes populations in normal and PEMS affected turkeys

Proceedings of the ... Western Poultry Disease Conference, 49(2000), 95–97.

By: E. De Buysscher, S. Tonkonogy, J. Vaillancourt & H. Barnes

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 276(6), G1461–G1472.

By: M. Schultz*, S. Tonkonogy n, R. Sellon n, C. Veltkamp*, V. Godfrey*, J. Kwon n, W. Grenther n, E. Balish*, I. Horak*, R. Sartor*

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: interleukin-2-deficient mice; luminal flora; colitis; animal models
MeSH headings : Animals; Colitis / etiology; Colitis / pathology; Colon / metabolism; Digestive System / pathology; Gastritis / etiology; Gastritis / pathology; Germ-Free Life; Hepatitis, Animal / etiology; Immunoglobulins / biosynthesis; Interleukin-2 / deficiency; Interleukin-2 / genetics; Interleukin-2 / metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout / genetics; Time Factors
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice

JOURNAL OF EXPERIMENTAL MEDICINE, 190(7), 1013–1023.

By: L. Haynes*, P. Linton*, S. Eaton*, S. Tonkonogy n & S. Swain*

co-author countries: United States of America 🇺🇸
author keywords: T cell receptor transgenic; CD4 cells; aging; IL-2; gamma c-binding cytokines
MeSH headings : Aging / immunology; Animals; CD4-Positive T-Lymphocytes / cytology; CD4-Positive T-Lymphocytes / immunology; Cell Differentiation / drug effects; Cell Differentiation / immunology; Cells, Cultured; Cytokines / biosynthesis; Cytokines / pharmacology; H-2 Antigens / immunology; Interferon-gamma / biosynthesis; Interferon-gamma / pharmacology; Interleukin-2 / biosynthesis; Interleukin-2 / pharmacology; Interleukin-4 / biosynthesis; Interleukin-4 / pharmacology; Interleukin-5 / biosynthesis; Interleukin-5 / pharmacology; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Receptors, Antigen, T-Cell, alpha-beta / genetics; Receptors, Antigen, T-Cell, alpha-beta / immunology; Recombinant Proteins / pharmacology; T-Lymphocytes / cytology; T-Lymphocytes / immunology; Th1 Cells / immunology; Th2 Cells / immunology
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Blockade of both L-selectin and alpha(4) integrins abrogates naive CD4 cell trafficking and responses in gut-associated lymphoid organs

INTERNATIONAL IMMUNOLOGY, 10(7), 961–968.

By: L. Bradley*, M. Malo, S. Fong, S. Tonkonogy* & . Watson

co-author countries: United States of America 🇺🇸
author keywords: adhesion molecules; CD4 T lymphocytes; homing; recirculation
MeSH headings : Animals; Antibodies, Monoclonal / pharmacology; Antigens, CD / physiology; CD4-Positive T-Lymphocytes / immunology; Endothelium, Lymphatic / immunology; Female; Integrin alpha4; L-Selectin / physiology; Lymph Nodes / cytology; Lymph Nodes / immunology; Lymphocyte Activation / physiology; Male; Mice; Mice, Inbred C57BL; Peyer's Patches / cytology; Peyer's Patches / immunology; Rats
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation ininterleukin-10-deficient mice

Infection and Immunity, 66(11), 5224–5231.

By: R. Sellon, S. Tonkonogy, M. Schultz, L. Dieleman, W. Grenther, E. Balish, D. Rennick, R. Sartor

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

L-selectin is not essential for naive CD4 cell trafficking or development of primary responses in Peyer's patches

EUROPEAN JOURNAL OF IMMUNOLOGY, 27(5), 1140–1146.

By: L. Bradley*, M. Malo*, S. Tonkonogy n & . Watson*

co-author countries: United States of America 🇺🇸
author keywords: CD4; Peyer's patch; L-selectin; trafficking
MeSH headings : Animals; Antibodies, Monoclonal / pharmacology; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; Cell Movement / immunology; L-Selectin / immunology; L-Selectin / physiology; Lymph Nodes / immunology; Lymphocyte Activation; Lymphocyte Depletion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peyer's Patches / cytology; Peyer's Patches / immunology
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Sensitized liposomes as an antigen delivery system for the stimulation of mucosal immunity

JOURNAL OF DRUG TARGETING, 5(1), 15–24.

By: C. Velez*, S. Tonkonogy n, S. Lichtman* & M. Cho*

co-author countries: United States of America 🇺🇸
author keywords: cell proliferation; ELISA; liposomes; mucosal immunity; ovalbumin
MeSH headings : Administration, Rectal; Animals; Antigens / administration & dosage; Antigens / immunology; Bile / immunology; Cholera Toxin / administration & dosage; Cholera Toxin / immunology; Drug Carriers; Feces / chemistry; Ferritins / immunology; Immunity, Mucosal / immunology; Immunoglobulin A / biosynthesis; Immunoglobulin G / biosynthesis; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Nitrophenols / chemistry; Nitrophenols / immunology; Ovalbumin / immunology; Peyer's Patches / immunology; Saliva / immunology
Source: Web Of Science
Added: August 6, 2018

1991 review

HELPER T-CELL SUBSETS - PHENOTYPE, FUNCTION AND THE ROLE OF LYMPHOKINES IN REGULATING THEIR DEVELOPMENT

[Review of ]. IMMUNOLOGICAL REVIEWS, 123, 115–144.

By: S. Swain*, L. Bradley*, M. Croft*, S. Tonkonogy*, G. Atkins*, A. Weinberg*, D. Duncan*, S. Hedrick*, R. Dutton*, G. Huston*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; Humans; Immunophenotyping; Lymphocyte Activation; Lymphokines / immunology; T-Lymphocyte Subsets / immunology; T-Lymphocytes, Helper-Inducer / immunology
Source: Web Of Science
Added: August 6, 2018

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