Works (22)

Updated: July 5th, 2023 14:43

2023 review

A Review on Recent Development of Novel Heterocycles as Acetylcholinesterase Inhibitor for the Treatment of Alzheimer's Disease

[Review of ]. CURRENT DRUG TARGETS, 24(3), 225โ€“246.

By: A. Patelโ€‰*, D. Shah*, Y. Patel*, S. Patelโ€‰*, M. Mehta* & T. Bambharoliya nโ€‰

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Alzheimer's disease (AD); Acetylcholinesterase (AChE); heterocyclic; scaffolds; CAS; peripheral anionic site (PAS)
MeSH headings : Humans; Cholinesterase Inhibitors / pharmacology; Cholinesterase Inhibitors / therapeutic use; Alzheimer Disease / drug therapy; Acetylcholinesterase / chemistry; Acetylcholinesterase / therapeutic use; Tacrine / pharmacology; Tacrine / therapeutic use; Tacrine / chemistry; Amyloid beta-Peptides
Source: Web Of Science
Added: April 17, 2023

2023 review

Mini Review on Cariprazine: A Promising Antipsychotic Agent

[Review of ]. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 22(2), 226โ€“236.

By: A. Patelโ€‰*, A. Patelโ€‰*, D. Patelโ€‰*, K. Patel* & T. Bambharoliya nโ€‰

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Cariprazine; Dopamine(D-2; D-3) Receptor; DCAR; DDCAR; Schizophrenia; Bipolar I disorder
MeSH headings : Antipsychotic Agents / pharmacology; Antipsychotic Agents / therapeutic use; Serotonin
Sources: ORCID, Web Of Science
Added: March 31, 2022

2023 article

Recent Progress for the Synthesis of ss-Carboline Derivatives - an Update

Patel, V., Bambharoliya, T., Shah, D., Patel, Y., Savaliya, N., Patel, Y., โ€ฆ Patel, A. (2023, February 20). POLYCYCLIC AROMATIC COMPOUNDS.

By: V. Patelโ€‰*, T. Bambharoliya nโ€‰, D. Shah*, Y. Patel*, N. Savaliya*, Y. Patelโ€‰*, R. Patel*, V. Bhavsarโ€‰* ...

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: beta-Carboline; pictet-spengler cyclization; pyrido[34-b]indole; Heterocycle
Source: Web Of Science
Added: March 20, 2023

2022 review

A review on synthetic investigation for quinoline- recent green approaches

[Review of ]. GREEN CHEMISTRY LETTERS AND REVIEWS, 15(2), 336โ€“371.

By: A. Patelโ€‰*, S. Patelโ€‰*, M. Mehta*, Y. Patel*, R. Patel*, D. Shah*, D. Patelโ€‰*, U. Shahโ€‰* ...

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: A. Patelโ€‰*, S. Patelโ€‰*, M. Mehta*, Y. Patel*, R. Patel*, D. Shah*, D. Patelโ€‰*, U. Shahโ€‰* ...

author keywords: Quinoline; green chemistry; microwave synthesis; solvent-free approach; multicomponent reaction
Sources: Web Of Science, ORCID
Added: April 25, 2022

2022 review

Development of Natural Bioactive Alkaloids: Anticancer Perspective

[Review of ]. MINI-REVIEWS IN MEDICINAL CHEMISTRY, 22(2), 200โ€“212.

By: A. Patelโ€‰*, R. Vanecha*, J. Patelโ€‰*, D. Patel*, U. Shahโ€‰* & T. Bambharoliya nโ€‰

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: A. Patelโ€‰*, R. Vanecha*, J. Patelโ€‰*, D. Patel*, U. Shahโ€‰* & T. Bambharoliya nโ€‰

author keywords: Natural alkaloids; anticancer agents; vinblastine; camptothecin; natural herbs; plant products
MeSH headings : Alkaloids / chemistry; Alkaloids / pharmacology; Alkaloids / therapeutic use; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Humans; Neoplasms / drug therapy; Neoplasms / pathology; Plants; Prospective Studies
Sources: ORCID, Web Of Science
Added: July 14, 2021

2022 journal article

In silico Study and Solvent-free one-pot Synthesis of Tetrahydropyrimidine derivatives by Mechanochemistry Approach for Targeting Human Neutrophil Elastase against Lung Cancer

CURRENT COMPUTER-AIDED DRUG DESIGN, 18(4), 293โ€“306.

By: A. Patelโ€‰*, K. Gandhiโ€‰*, S. Shah*, D. Patelโ€‰*, S. Chhatbar*, D. Shah*, S. Patelโ€‰*, H. Patel*, T. Bambharoliya nโ€‰

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Biginelii condensation; mechanochemistry; human neutrophil elastase; tetrahydropyrimidine; lung cancer; green chemistry
MeSH headings : Humans; Leukocyte Elastase / chemistry; Leukocyte Elastase / metabolism; Molecular Docking Simulation; Solvents; Lung Neoplasms / drug therapy
Sources: Web Of Science, ORCID
Added: November 14, 2022

2022 review

Recent Update on the Development of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors: A Promising Target for the Treatment of Parkinson's Disease

[Review of ]. MEDICINAL CHEMISTRY, 18(7), 757โ€“771.

By: A. Patelโ€‰*, S. Patelโ€‰*, M. Mehta*, Y. Patel*, D. Langaliya*, S. Bhalodiya*, T. Bambharoliya nโ€‰

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: A. Patelโ€‰*, S. Patelโ€‰*, M. Mehta*, Y. Patel*, D. Langaliya*, S. Bhalodiya*, T. Bambharoliya nโ€‰

author keywords: Leucine-rich repeat kinase 2 (LRRK2); Parkinson's disease (PD); brain penetrant LRKK2 inhibitors; G2019S-LRRK2 mutant; wild-type LRKK2; promising target
MeSH headings : Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / antagonists & inhibitors; Parkinson Disease / drug therapy; Protein Kinase Inhibitors / pharmacology; Protein Kinase Inhibitors / therapeutic use
Sources: ORCID, Web Of Science
Added: June 27, 2022

2021 review

A Review on the Synthetic Approach of Marinopyrroles: A Natural Anti-tumor Agent from the Ocean

[Review of ]. LETTERS IN ORGANIC CHEMISTRY, 18(4), 251โ€“264.

By: A. Patelโ€‰*, H. Shah*, U. Shahโ€‰*, T. Bambharoliya nโ€‰, M. Patelโ€‰*, I. Panchalโ€‰*, V. Parikh*, A. Nagani* ...

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: A. Patelโ€‰*, H. Shah*, U. Shahโ€‰*, T. Bambharoliya nโ€‰, M. Patelโ€‰*, I. Panchalโ€‰*, V. Parikh*, A. Nagani* ...

author keywords: Marinopyrroles; bis-pyrrole; anti-tumor agents; new chemical entities; natural products; streptomycete
Sources: Web Of Science, ORCID
Added: May 10, 2021

2021 journal article

A hybrid vascular graft harnessing the superior mechanical properties of synthetic fibers and the biological performance of collagen filaments

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 118.

By: F. Zhang nโ€‰, T. Bambharoliya nโ€‰, Y. Xie n, L. Liuโ€‰*, H. Celikโ€‰*, L. Wangโ€‰*, O. Akkus*, M. King nโ€‰

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: F. Zhang nโ€‰, T. Bambharoliya nโ€‰, Y. Xie n, L. Liuโ€‰*, H. Celikโ€‰*, L. Wangโ€‰*, O. Akkus*, M. King nโ€‰

author keywords: Tissue-engineered vascular graft; Biomaterial; Hybrid; Electrochemically aligned collagen; Poly (lactic acid)
MeSH headings : Biocompatible Materials / pharmacology; Blood Vessel Prosthesis; Collagen; Endothelial Cells; Tissue Engineering; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: January 19, 2021

2021 journal article

Benzimidazole as Ubiquitous Structural Fragment: An Update on Development of its Green Synthetic Approaches

MINI-REVIEWS IN ORGANIC CHEMISTRY, 18(8).

By: A. Patelโ€‰*, D. Shah*, N. Patel*, K. Patelโ€‰*, N. Soni*, A. Nagani*, V. Parikh*, H. Shah*, T. Bambharoliya nโ€‰

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: A. Patelโ€‰*, D. Shah*, N. Patel*, K. Patelโ€‰*, N. Soni*, A. Nagani*, V. Parikh*, H. Shah*, T. Bambharoliya nโ€‰

author keywords: Benzimidazole; green chemistry; o-phenylenediamine; aromatic aldehyde; synthesis; sustainable chemistry
Sources: ORCID, Web Of Science
Added: December 16, 2020

2021 journal article

Exploring the in-silico approach for assessing the potential of natural compounds as a SARS-CoV-2 main protease inhibitors

ORGANIC COMMUNICATIONS, 14(1), 58โ€“72.

By: A. Patel, A. Patel, R. Hemani, R. Solanki, J. Kansara, G. Patel, S. Pradhan, T. Bambharoliya*โ€‰

Contributors: A. Patel, A. Patel, R. Hemani, R. Solanki, J. Kansara, G. Patel, S. Pradhan, T. Bambharoliya*โ€‰

author keywords: SARS-CoV-2; main protease; natural products; molecular docking; viral infection; drug-likeness
Sources: ORCID, Web Of Science
Added: April 26, 2021

2021 review

Quinoxaline as Ubiquitous Structural Fragment: An Update on the Recent Develop-ment of its Green Synthetic Approaches

[Review of ]. CURRENT ORGANIC CHEMISTRY, 25(24), 3004โ€“3016.

By: A. Patelโ€‰*, D. Shah*, N. Patel*, K. Patelโ€‰*, N. Soni*, A. Nagai*, U. Shahโ€‰*, M. Patelโ€‰* ...

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: A. Patelโ€‰*, D. Shah*, N. Patel*, K. Patelโ€‰*, N. Soni*, A. Nagai*, U. Shahโ€‰*, M. Patelโ€‰* ...

author keywords: Quinoxaline; green chemistry; o-phenylenediamine; sustainable chemistry; conventional method; microwave irradiation
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

Ultrasound-Assisted One-Pot Synthesis of Tetrahydropyrimidne Derivatives through Biginelli Condensation: A Catalyst Free Green Chemistry Approach

LETTERS IN ORGANIC CHEMISTRY, 18(9), 749โ€“756.

By: A. Patelโ€‰*, J. Shah*, K. Patel*, K. Patel*, H. Patel*, D. Dobaria*, U. Shahโ€‰*, M. Patelโ€‰* ...

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: A. Patelโ€‰*, J. Shah*, K. Patel*, K. Patel*, H. Patel*, D. Dobaria*, U. Shahโ€‰*, M. Patelโ€‰* ...

author keywords: Biginelli condensation; catalyst free; sonochemistry; tetrahydropyrimidine; ultrasound-assisted; sustainable chemistry
Sources: Web Of Science, ORCID
Added: August 16, 2021

2020 chapter

Coronary Artery Disease and The Evolution of Angioplasty Devices

In SpringerBriefs in Materials (pp. 1โ€“62). http://www.scopus.com/inward/record.url?eid=2-s2.0-85127797918&partnerID=MN8TOARS

By: M. King, T. Bambharoliyaโ€‰, H. Ramakrishna & F. Zhang

Contributors: M. King, T. Bambharoliyaโ€‰, H. Ramakrishna & F. Zhang

Source: ORCID
Added: June 27, 2022

2020 chapter

Coronary Microvascular Dysfunction (CMD)

In SpringerBriefs in Materials (pp. 11โ€“14).

By: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

Source: ORCID
Added: June 27, 2022

2020 chapter

Definitions and Basic Mechanism of Coronary Artery Disease (CAD)

In SpringerBriefs in Materials (pp. 3โ€“10).

By: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

Source: ORCID
Added: June 27, 2022

2020 chapter

Diagnosis of Coronary Artery Disease (CAD)

In SpringerBriefs in Materials (pp. 15โ€“20).

By: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

Source: ORCID
Added: June 27, 2022

2020 chapter

Epidemiology and Risk Factors

In SpringerBriefs in Materials (pp. 1โ€“2).

By: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

Source: ORCID
Added: June 27, 2022

2020 chapter

Evolution of Angioplasty Devices

In SpringerBriefs in Materials (pp. 31โ€“52).

By: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

Source: ORCID
Added: June 27, 2022

2020 journal article

The ฮฒ-Secretase Enzyme BACE1: A Biochemical Enigma for Alzheimerโ€™s Disease

CNS & Neurological Disorders - Drug Targets, 19(3), 184โ€“194.

By: H. Shah*, A. Patelโ€‰*, V. Parikh*, A. Nagani*, B. Bhimani*, U. Shahโ€‰*, T. Bambharoliya nโ€‰

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: H. Shah*, A. Patelโ€‰*, V. Parikh*, A. Nagani*, B. Bhimani*, U. Shahโ€‰*, T. Bambharoliya nโ€‰

author keywords: Alzheimer's disease; Amyloid Precursor Protein (APP); BACE1; Amyloid beta (A beta); beta-pathway; palmitoylation
MeSH headings : Alzheimer Disease / metabolism; Amyloid Precursor Protein Secretases / metabolism; Amyloid beta-Peptides / metabolism; Amyloid beta-Protein Precursor / metabolism; Animals; Aspartic Acid Endopeptidases / metabolism; Brain / metabolism; Humans; Protein Processing, Post-Translational
Source: ORCID
Added: May 29, 2020

2020 chapter

Treatment of Coronary Artery Disease (CAD)

In SpringerBriefs in Materials (pp. 21โ€“29).

By: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ

Contributors: M. King n, T. Bambharoliya nโ€‰, H. Ramakrishna n & F. Zhangโ€‰ n

Source: ORCID
Added: June 27, 2022

2019 conference paper

Design and development of stent coated with novel cardiac stem cell-mimicking regenerative factors

Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, 40, 481. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065394023&partnerID=MN8TOARS

By: T. Bambharoliyaโ€‰, S. Hu, K. Cheng & M. King

Contributors: T. Bambharoliyaโ€‰, S. Hu, K. Cheng & M. King

Source: ORCID
Added: June 27, 2022

Employment

Updated: May 21st, 2023 18:31

2023 - present

BD Lexington, Massachusetts, US
Manager of Manufacturing

2020 - 2023

BD Lexington, Massachusetts, US
Extrusion Development Engineer

2015 - 2021

NC State University Raleigh, NC, US
Graduate Research Assistant Wilson College of Textiles

2011 - 2015

Nano Therapeutics Pvt Ltd Surat, Gujarat, IN
Sr. Executive Research and Developement

Education

Updated: January 8th, 2023 18:45

2015 - 2020

NC State University Raleigh, NC, US
PhD (Major- Fiber and Polymer Science and Minor- Biomedical Engineering) Wilson College of Textiles

2009 - 2011

Nirma University Ahmedabad, Gujarat, IN
Master in Pharmaceutical Technology and Biopharmaceutics College of Pharmacy