Thomas Conrad Wiegers

Works (26)

Updated: July 21st, 2023 21:14

2022 article

Comparative Toxicogenomics Database (CTD): update 2023

Davis, A. P., Wiegers, T. C., Johnson, R. J., Sciaky, D., Wiegers, J., & Mattingly, C. J. (2022, September 28). NUCLEIC ACIDS RESEARCH, Vol. 9.

By: A. Davis n, T. Wiegers n, R. Johnson n, D. Sciaky n, J. Wiegers n & C. Mattingly n

MeSH headings : Humans; Toxicogenetics; Databases, Factual; Phenotype
Sources: Web Of Science, ORCID
Added: October 11, 2022

2021 journal article

CTD anatomy: Analyzing chemical-induced phenotypes and exposures from an anatomical perspective, with implications for environmental health studies

CURRENT RESEARCH IN TOXICOLOGY, 2, 128–139.

By: A. Davis n, T. Wiegers n, J. Wiegers n, C. Grondin n, R. Johnson n, D. Sciaky n, C. Mattingly n

author keywords: Anatomy; Chemical; Phenotype; Disease; Environmental health; Database
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

Comparative Toxicogenomics Database (CTD): update 2021

NUCLEIC ACIDS RESEARCH, 49(D1), D1138–D1143.

By: A. Davis n, C. Grondin n, R. Johnson n, D. Sciaky n, J. Wiegers n, T. Wiegers n, C. Mattingly n

MeSH headings : Databases, Chemical; Databases, Factual; Databases, Genetic; Gene-Environment Interaction; Genome, Human / drug effects; Genomics / methods; Genotype; Humans; Internet; Knowledge Bases; Organ Specificity; Phenotype; Prescription Drugs / chemistry; Prescription Drugs / pharmacology; Software; Toxicogenetics / methods; Xenobiotics / chemistry; Xenobiotics / toxicity
Sources: Web Of Science, ORCID
Added: February 8, 2021

2021 journal article

Predicting molecular mechanisms, pathways, and health outcomes induced by Juul e-cigarette aerosol chemicals using the Comparative Toxicogenomics Database

CURRENT RESEARCH IN TOXICOLOGY, 2, 272–281.

By: C. Grondin n, A. Davis n, J. Wiegers n, T. Wiegers n, D. Sciaky n, R. Johnson n, C. Mattingly n

author keywords: E-cigarettes; Vaping; Juul; Respiratory disease; Database; Environmental exposure
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

Regulatory status of pesticide residues in cannabis: Implications to medical use in neurological diseases

CURRENT RESEARCH IN TOXICOLOGY, 2, 140–148.

author keywords: Cannabis; Pesticide; Database; Regulation; Seizure; Contaminant
Sources: Web Of Science, ORCID
Added: January 3, 2022

2020 journal article

Leveraging the Comparative Toxicogenomics Database to Fill in Knowledge Gaps for Environmental Health: A Test Case for Air Pollution-induced Cardiovascular Disease

TOXICOLOGICAL SCIENCES, 177(2), 392–404.

author keywords: environmental health; chemical-induced pathways; air pollution; cardiovascular disease; database
MeSH headings : Air Pollutants / toxicity; Air Pollution; Cardiovascular Diseases / chemically induced; Environmental Exposure; Environmental Health; Humans; Toxicogenetics
Sources: Web Of Science, ORCID
Added: December 14, 2020

2019 journal article

The Comparative Toxicogenomics Database: update 2019

NUCLEIC ACIDS RESEARCH, 47(D1), D948–D954.

By: A. Davis n, C. Grondin n, R. Johnson n, D. Sciaky n, R. McMorran*, J. Wiegers n, T. Wiegers n, C. Mattingly n

MeSH headings : Databases, Pharmaceutical; Disease / genetics; Environmental Exposure; Humans; Phenotype; Toxicogenetics; Vocabulary, Controlled
Sources: Web Of Science, ORCID
Added: April 9, 2019

2018 journal article

Accessing an Expanded Exposure Science Module at the Comparative Toxicogenomics Database

ENVIRONMENTAL HEALTH PERSPECTIVES, 126(1).

By: C. Grondin n, A. Davis n, T. Wiegers n, J. Wiegers n & C. Mattingly n

MeSH headings : Databases, Factual; Environmental Exposure / adverse effects; Gene Ontology; Humans; Phenotype; Toxicogenetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Chemical-Induced Phenotypes at CTD Help Inform the Predisease State and Construct Adverse Outcome Pathways

TOXICOLOGICAL SCIENCES, 165(1), 145–156.

By: A. Davis*, T. Wiegers*, J. Wiegers*, R. Johnson*, D. Sciaky*, C. Grondin, C. Mattingly n

author keywords: phenotype; database; curation; chemical; disease; adverse outcome pathway
MeSH headings : Adverse Outcome Pathways; Animals; Databases, Factual; Drug-Related Side Effects and Adverse Reactions / genetics; Gene Ontology; Gene-Environment Interaction; Humans; Phenotype; Toxicogenetics / methods
Sources: Web Of Science, ORCID
Added: October 16, 2018

2017 journal article

The Comparative Toxicogenomics Database: update 2017

NUCLEIC ACIDS RESEARCH, 45(D1), D972–D978.

By: A. Davis n, C. Grondin n, R. Johnson n, D. Sciaky n, B. King*, R. McMorran*, J. Wiegers n, T. Wiegers n, C. Mattingly n

MeSH headings : Computational Biology / methods; Databases, Chemical; Databases, Genetic; Gene Ontology; Humans; Search Engine; Signal Transduction; Toxicogenetics / methods; User-Computer Interface; Web Browser
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database

Environmental Health Perspectives, 124(10), 1592–1599.

By: C. Grondin n, A. Davis n, T. Wiegers n, B. King*, J. Wiegers n, D. Reif n, J. Hoppin n, C. Mattingly n

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Assessing the state of the art in biomedical relation extraction: overview of the BioCreative V chemical-disease relation (CDR) task

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

MeSH headings : Biomedical Research; Data Mining / methods; Databases, Factual; Disease; Humans; Statistics as Topic; Time Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

BioCreative V CDR task corpus: a resource for chemical disease relation extraction

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: J. Li*, Y. Sun*, R. Johnson n, D. Sciaky n, C. Wei*, R. Leaman*, A. Davis n, C. Mattingly n ...

MeSH headings : Computational Biology / methods; Data Mining / methods; Databases, Factual; Disease; Humans; Toxicogenetics / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database

PLOS ONE, 11(5).

By: A. Davis n, T. Wiegers n, B. King*, J. Wiegers n, C. Grondin n, D. Sciaky n, R. Johnson n, C. Mattingly n

MeSH headings : Computational Biology; Databases, Genetic; Disease / genetics; Drug Repositioning; Gene Ontology; Humans; Toxicogenetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

ToxEvaluator: an integrated computational platform to aid the interpretation of toxicology study-related findings

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: D. Pelletier*, T. Wiegers n, A. Enayetallah*, C. Kibbey*, M. Gosink*, P. Koza-Taylor*, C. Mattingly n, M. Lawton*

MeSH headings : Animals; Computational Biology / methods; Computer Simulation; Database Management Systems; Databases, Factual; Humans; Mice; Toxicogenetics / methods; User-Computer Interface
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

The Comparative Toxicogenomics Database's 10th year anniversary: update 2015

NUCLEIC ACIDS RESEARCH, 43(D1), D914–D920.

By: A. Davis n, C. Grondin n, K. Lennon-Hopkins n, C. Saraceni-Richards n, D. Sciaky n, B. King*, T. Wiegers n, C. Mattingly n

MeSH headings : Databases, Chemical / history; Disease / etiology; Disease / genetics; Genomics / history; History, 21st Century; Internet; Phenotype; Toxicogenetics / history
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

BioC interoperability track overview

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: D. Comeau*, R. Batista-Navarro*, H. Dai*, R. Dogan*, A. Yepes*, R. Khare*, Z. Lu*, H. Marques* ...

MeSH headings : Biomedical Research; Computational Biology; Data Mining; Database Management Systems; Databases, Factual; Internet; Natural Language Processing; Software
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 article

BioCreative-IV virtual issue

Arighi, C. N., Wu, C. H., Cohen, K. B., Hirschman, L., Krallinger, M., Valencia, A., … Wiegers, T. C. (2014, May 22). DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: C. Arighi*, C. Wu*, K. Cohen*, L. Hirschman*, M. Krallinger*, A. Valencia*, Z. Lu*, J. Wilbur*, T. Wiegers n

MeSH headings : Computational Biology; Congresses as Topic; Data Mining; Databases as Topic; Gene Ontology; Natural Language Processing
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Web services-based text-mining demonstrates broad impacts for interoperability and process simplification

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: T. Wiegers n, A. Davis n & C. Mattingly n

MeSH headings : Data Mining / methods; Databases, Chemical; Databases, Genetic; Disease / genetics; Genes; Internet; Time Factors; Toxicogenetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

A CTD-Pfizer collaboration: manual curation of 88 000 scientific articles text mined for drug-disease and drug-phenotype interactions

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: A. Davis n, T. Wiegers n, P. Roberts n, B. King n, J. Lay n, K. Lennon-Hopkins n, D. Sciaky n, R. Johnson n ...

MeSH headings : Cooperative Behavior; Data Mining; Databases, Factual; Disease; Drug Industry; Humans; Pharmaceutical Preparations / metabolism; Phenotype; Publications; Toxicogenetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

BioC: a minimalist approach to interoperability for biomedical text processing

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: D. Comeau*, R. Dogan*, P. Ciccarese*, K. Cohen*, M. Krallinger*, F. Leitner*, Z. Lu*, Y. Peng* ...

MeSH headings : Biomedical Research; Data Mining; Humans; Natural Language Processing; Software
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Text Mining Effectively Scores and Ranks the Literature for Improving Chemical-Gene-Disease Curation at the Comparative Toxicogenomics Database

PLOS ONE, 8(4).

By: A. Davis n, T. Wiegers n, R. Johnson*, J. Lay*, K. Lennon-Hopkins*, C. Saraceni-Richards*, D. Sciaky*, C. Murphy n, C. Mattingly n

MeSH headings : Algorithms; Data Mining / methods; Databases, Factual; Disease / genetics; Documentation; Humans; Metals, Heavy / toxicity; Molecular Sequence Annotation; Publications; Reproducibility of Results; Toxicogenetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 article

BioCreative-2012 Virtual Issue

Wu, C. H., Arighi, C. N., Cohen, K. B., Hirschman, L., Krallinger, M., Lu, Z. Y., … al. (2012, December 5). DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION.

By: C. Wu*, C. Arighi*, K. Cohen*, L. Hirschman*, M. Krallinger*, Z. Lu*, C. Mattingly*, A. Valencia* ...

MeSH headings : Congresses as Topic; Cooperative Behavior; Data Mining; Databases, Genetic; Periodicals as Topic; Workflow
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Collaborative biocuration--text-mining development task for document prioritization for curation

Database, 2012(0), bas037–bas037.

By: T. Wiegers n, A. Davis n & C. Mattingly n

MeSH headings : Cooperative Behavior; Data Mining / methods; Databases, Genetic; Disease; Documentation / methods; Genes; Humans; Internet; Toxicogenetics; User-Computer Interface
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2012 journal article

Ranking Transitive Chemical-Disease Inferences Using Local Network Topology in the Comparative Toxicogenomics Database

PLOS ONE, 7(11).

By: B. King*, A. Davis n, M. Rosenstein*, T. Wiegers n & C. Mattingly n

MeSH headings : Cluster Analysis; Databases, Factual; Drug-Related Side Effects and Adverse Reactions / genetics; Gene Regulatory Networks; Humans; Protein Interaction Mapping; Toxicogenetics / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Targeted journal curation as a method to improve data currency at the Comparative Toxicogenomics Database

Database-The Journal of Biological Databases and Curation.

By: A. Davis, R. Johnson, K. Lennon-Hopkins, D. Sciaky, M. Rosenstein, T. Wiegers, C. Mattingly

Source: NC State University Libraries
Added: August 6, 2018