Tobias Kaeser

Proctor, J., Stadler, M., Cortes, L. M., Brodsky, D., Poisson, L., Gerdts, V., … Kaeser, T. (2024). A TriAdj-Adjuvanted <i>Chlamydia trachomatis</i> CPAF Protein Vaccine Is Highly Immunogenic in Pigs. Vaccines. https://doi.org/10.3390/vaccines12040423

Kick, A. R., Grete, A. F., Crisci, E., Almond, G. W., & Käser, T. (2023). Testable Candidate Immune Correlates of Protection for Porcine Reproductive and Respiratory Syndrome Virus Vaccination. Vaccines, 11(3), 594. https://doi.org/10.3390/vaccines11030594

Sper, R. B., Proctor, J., Lascina, O., Guo, L., Polkoff, K., Kaeser, T., … Piedrahita, J. A. (2022). Allogeneic and xenogeneic lymphoid reconstitution in a RAG2(-/-)IL2RG(y/-) severe combined immunodeficient pig: A preclinical model for intrauterine hematopoietic transplantation. FRONTIERS IN VETERINARY SCIENCE, 9. https://doi.org/10.3389/fvets.2022.965316

Proctor, J., Wolf, I., Brodsky, D., Cortes, L. M., Frias-De-Diego, A., Almond, G. W., … Käser, T. (2022). Heterologous vaccine immunogenicity, efficacy, and immune correlates of protection of a modified-live virus porcine reproductive and respiratory syndrome virus vaccine. Frontiers in Microbiology, 13. https://doi.org/10.3389/fmicb.2022.977796

Cortes, L. M., Brodsky, D., Chen, C., Pridgen, T., Odle, J., Snider, D. B., … Kaser, T. (2022). Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis. FRONTIERS IN ALLERGY, 3. https://doi.org/10.3389/falgy.2022.1029184

Amaral, A. F., McQueen, B. E., Bellingham-Johnstun, K., Poston, T. B., Darville, T., Nagarajan, U. M., … Kaser, T. (2021). Host-Pathogen Interactions of Chlamydia trachomatis in Porcine Oviduct Epithelial Cells. PATHOGENS, 10(10). https://doi.org/10.3390/pathogens10101270

Kick, A. R., Wolfe, Z. C., Amaral, A. E., Cortes, L. M., Almond, G. W., Crisci, E., … Kaeser, T. (2021). Maternal Autogenous Inactivated Virus Vaccination Boosts Immunity to PRRSV in Piglets. VACCINES, 9(2). https://doi.org/10.3390/vaccines9020106

Kaser, T. (2021). Swine as biomedical animal model for T-cell research-Success and potential for transmittable and non-transmittable human diseases. MOLECULAR IMMUNOLOGY, 135, 95–115. https://doi.org/10.1016/j.molimm.2021.04.004

Kick, A. R., Wolfe, Z. C., Amaral, A. F., Cortes, L. M., Almond, G. W., Crisci, E., … Käser, T. (2020, December 3). Maternal Autogenous Inactivated Virus Vaccination Boosts the Piglet Humoral and Cell-Mediated Immunity to PRRSV via Transfer of Neutralizing Antibodies and Interferon-Gamma Producing B Cells (Vol. 12). Vol. 12. https://doi.org/10.20944/preprints202012.0074.v1

Amaral, A. F., Rahman, K. S., Kick, A. R., Cortes, L. M., Robertson, J., Kaltenboeck, B., … Kaeser, T. (2020). Mucosal Vaccination with UV-Inactivated <i>Chlamydia suis</i> in Pre-Exposed Outbred Pigs Decreases Pathogen Load and Induces CD4 T-Cell Maturation into IFN-γ<sup>+</sup> Effector Memory Cells. Vaccines, 8(3), 353. https://doi.org/10.3390/vaccines8030353

Rodriguez-Gomez, I. M., Talker, S. C., Kaeser, T., Stadler, M., Reiter, L., Ladinig, A., … Gerner, W. (2019). Expression of T-Bet, Eomesodermin, and GATA-3 Correlates With Distinct Phenotypes and Functional Properties in Porcine gamma delta T Cells. FRONTIERS IN IMMUNOLOGY, 10. https://doi.org/10.3389/fimmu.2019.00396

Kick, A., Amaral, A., Cortes, L., Fogle, J., Crisci, E., Almond, G., & Käser, T. (2019). The T-Cell Response to Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Viruses, 11(9), 796. https://doi.org/10.3390/v11090796

Käser, T., Renois, F., Wilson, H. L., Cnudde, T., Gerdts, V., Dillon, J.-A. R., … Meurens, F. (2018). Contribution of the swine model in the study of human sexually transmitted infections. Infection, Genetics and Evolution, 66, 346–360. https://doi.org/10.1016/j.meegid.2017.11.022

Hamonic, G., Pasternak, J. A., Forsberg, N. M., Käser, T., & Wilson, H. L. (2018). Expression of pattern recognition receptors in porcine uterine epithelial cells in vivo and in culture. Veterinary Immunology and Immunopathology, 202, 1–10. https://doi.org/10.1016/J.VETIMM.2018.06.006

Bauer, T., Sipos, W., Stark, T. D., Kaeser, T., Knecht, C., Brunthaler, R., … Ehling-Schulz, M. (2018). First Insights Into Within Host Translocation of the Bacillus cereus Toxin Cereulide Using a Porcine Model. FRONTIERS IN MICROBIOLOGY, 9. https://doi.org/10.3389/fmicb.2018.02652

Käser, T. (2017). Challenges and efforts in vaccine development and distribution. Vaccine. https://doi.org/10.1016/j.vaccine.2017.07.091

Käser, T., Pasternak, J. A., Delgado-Ortega, M., Hamonic, G., Lai, K., Erickson, J., … Meurens, F. (2017). Chlamydia suis and Chlamydia trachomatis induce multifunctional CD4 T cells in pigs. Vaccine, 35(1), 91–100. https://doi.org/10.1016/j.vaccine.2016.11.050

Rodríguez-Gómez, I. M., Talker, S. C., Käser, T., Stadler, M., Hammer, S. E., Saalmüller, A., & Gerner, W. (2016). Expression of T-bet, Eomesodermin and GATA-3 in porcine αβ T cells. Developmental and Comparative Immunology, 60, 115–126. https://doi.org/10.1016/j.dci.2016.02.022

Hamonic, G., Pasternak, J. A., Käser, T., Meurens, F., & Wilson, H. L. (2016). Extended semen for artificial insemination in swine as a potential transmission mechanism for infectious Chlamydia suis. Theriogenology, 86(4), 949–956. https://doi.org/10.1016/j.theriogenology.2016.03.018

Käser, T., Pasternak, J. A., Hamonic, G., Rieder, M., Lai, K., Delgado-Ortega, M., … Meurens, F. (2016). Flow cytometry as an improved method for the titration of Chlamydiaceae and other intracellular bacteria. Cytometry Part A, 89(5), 451–460. https://doi.org/10.1002/cyto.a.22822

Bähr, A., Käser, T., Kemter, E., Gerner, W., Kurome, M., Baars, W., … Klymiuk, N. (2016). Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs. PLOS ONE, 11(5), e0155676. https://doi.org/10.1371/journal.pone.0155676

Käser, T., Mair, K. H., Hammer, S. E., Gerner, W., & Saalmüller, A. (2015). Natural and inducible Tregs in swine: Helios expression and functional properties. Developmental and Comparative Immunology, 49(2), 323–331. https://doi.org/10.1016/j.dci.2014.12.005

Rodríguez-Gómez, I. M., Käser, T., Gómez-Laguna, J., Lamp, B., Sinn, L., Rümenapf, T., … Gerner, W. (2015). PRRSV-infected monocyte-derived dendritic cells express high levels of SLA-DR and CD80/86 but do not stimulate PRRSV-naïve regulatory T cells to proliferate. Veterinary Research, 46(1). https://doi.org/10.1186/s13567-015-0186-z

Käser, T., Cnudde, T., Hamonic, G., Rieder, M., Pasternak, J. A., Lai, K., … Meurens, F. (2015). Porcine retinal cell line VIDO R1 and Chlamydia suis to modelize ocular chlamydiosis. Veterinary Immunology and Immunopathology, 166(3-4), 95–107. https://doi.org/10.1016/j.vetimm.2015.06.003

Paudel, S., Hess, C., Wernsdorf, P., Käser, T., Meitz, S., Jensen-Jarolim, E., … Liebhart, D. (2015). The systemic multiplication of Gallibacterium anatis in experimentally infected chickens is promoted by immunosuppressive drugs which have a less specific effect on the depletion of leukocytes. Veterinary Immunology and Immunopathology, 166(1-2), 22–32. https://doi.org/10.1016/j.vetimm.2015.05.001

Mair, K. H., Sedlak, C., Käser, T., Pasternak, A., Levast, B., Gerner, W., … Meurens, F. (2014). The porcine innate immune system: An update. Developmental and Comparative Immunology, 45(2), 321–343. https://doi.org/10.1016/j.dci.2014.03.022

Rodríguez-Gómez, I. M., Burgara-Estrella, A. J., Mateu, E., Gómez-Laguna, J., Carrasco, L., Saalmüller, A., & Käser, T. (2013). Effect of Two Strains of PRRSV on the Expression of Differentiation Antigens of Monocyte-derived Dendritic Cells. Journal of Comparative Pathology, 148(1), 51. https://doi.org/10.1016/j.jcpa.2012.11.026

Balmayor, E. R., Flicker, M., Käser, T., Saalmüller, A., & Erben, R. G. (2013). Human Placental Alkaline Phosphatase as a Tracking Marker for Bone Marrow Mesenchymal Stem Cells. BioResearch Open Access, 2(5), 346–355. https://doi.org/10.1089/biores.2013.0027

Balka, G., Ladinig, A., Ritzmann, M., Saalmüller, A., Gerner, W., Käser, T., … Weißenböck, H. (2013). Immunohistochemical characterization of type II pneumocyte proliferation after challenge with type I porcine reproductive and respiratory syndrome virus. Journal of Comparative Pathology, 149(2-3), 322–330. https://doi.org/10.1016/j.jcpa.2012.12.006

Talker, S. C., Käser, T., Reutner, K., Sedlak, C., Mair, K. H., Koinig, H., … Gerner, W. (2013). Phenotypic maturation of porcine NK- and T-cell subsets. Developmental and Comparative Immunology, 40(1), 51–68. https://doi.org/10.1016/j.dci.2013.01.003

Käser, T., Gerner, W., Mair, K., Hammer, S. E., Patzl, M., & Saalmüller, A. (2012). Current knowledge on porcine regulatory T cells. Veterinary Immunology and Immunopathology, 148(1-2), 136–138. https://doi.org/10.1016/j.vetimm.2011.05.035

Käser, T., Müllebner, A., Hartl, R. T., Essler, S. E., Saalmüller, A., & Catharina Duvigneau, J. (2012). Porcine T-helper and regulatory T cells exhibit versatile mRNA expression capabilities for cytokines and co-stimulatory molecules. Cytokine, 60(2), 400–409. https://doi.org/10.1016/j.cyto.2012.07.007

Käser, T., Gerner, W., & Saalmüller, A. (2011). Porcine regulatory T cells: Mechanisms and T-cell targets of suppression. Developmental & Comparative Immunology, 35(11), 1166–1172. https://doi.org/10.1016/j.dci.2011.04.006

Gerner, W., Hammer, S., Käser, T., Diny, N., Pintaric, M., & Saalmüller, A. (2009). Characterization of CD79α+CD21− B cells in swine. Veterinary Immunology and Immunopathology, 128(1-3), 274. https://doi.org/10.1016/j.vetimm.2008.10.137

Bolzer, K., Käser, T., Saalmüller, A., & Hammer, S. E. (2009). Molecular characterisation of porcine Forkhead-box p3 (Foxp3). Veterinary Immunology and Immunopathology, 132(2-4), 275–281. https://doi.org/10.1016/j.vetimm.2009.05.014

Gerner, W., Käser, T., & Saalmüller, A. (2009). Porcine T lymphocytes and NK cells - An update. Developmental and Comparative Immunology, 33(3), 310–320. https://doi.org/10.1016/j.dci.2008.06.003

Käser, T., Gerner, W., Hammer, S. E., Patzl, M., & Saalmüller, A. (2008). Detection of Foxp3 protein expression in porcine T lymphocytes. Veterinary Immunology and Immunopathology, 125(1-2), 92–101. https://doi.org/10.1016/j.vetimm.2008.05.007

Detection of intracellular antigens in porcine PBMC by flow cytometry: A comparison of fixation and permeabilisation reagents. (2008). Veterinary Immunology and Immunopathology, 121(3-4), 251–259. https://doi.org/10.1016/j.vetimm.2007.09.019

Käser, T., Gerner, W., Hammer, S. E., Patzl, M., & Saalmüller, A. (2008). Phenotypic and functional characterisation of porcine CD4+CD25high regulatory T cells. Veterinary Immunology and Immunopathology, 122(1-2), 153–158. https://doi.org/10.1016/j.vetimm.2007.08.002

A TriAdj-Adjuvanted <em>Chlamydia trachomatis </em>CPAF Protein Vaccine Is Highly Immunogenic in Pigs. https://doi.org/10.20944/preprints202403.0298.v1

Pasternak, J. A., Hon Ng, S. L., Käser, T., Meurens, F., & Wilson, H. L. Grouping Pig-Specific Responses to Mitogen with Similar Responder Animals may Facilitate the Interpretation of Results Obtained in an Out-Bred Animal Model. Journal of Vaccines and Vaccination, 5, 1–9.