Troy Ghashghaei

Zhang, X., Xiao, G., Johnson, C., Cai, Y., Horowitz, Z. K., Mennicke, C., … Ghashghaei, H. T. (2023). Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain. ISCIENCE, 26(3). https://doi.org/10.1016/j.isci.2023.106242

Cai, Y., Zhang, X., Li, C., Ghashghaei, H. T., & Greenbaum, A. (2023). COMBINe enables automated detection and classification of neurons and astrocytes in tissue-cleared mouse brains. CELL REPORTS METHODS, 3(4). https://doi.org/10.1016/j.crmeth.2023.100454

Rai, M. R., Li, C., Ghashghaei, H. T., & Greenbaum, A. (2023). Deep learning-based adaptive optics for light sheet fluorescence microscopy. BIOMEDICAL OPTICS EXPRESS, 14(6), 2905–2919. https://doi.org/10.1364/BOE.488995

LI, C., Moatti, A., Zhang, X., Ghashghaei, H. T., & Greenbaum, A. (2022, January 1). Deep learning-based autofocus method enhances image quality in light-sheet fluorescence microscopy: publishers note (vol 12, pg 5214, 2021). BIOMEDICAL OPTICS EXPRESS, Vol. 13, pp. 373–373. https://doi.org/10.1364/BOE.450829

Li, C., Rai, M. R., Ghashghaei, H. T., & Greenbaum, A. (2022). Illumination angle correction during image acquisition in light-sheet fluorescence microscopy using deep learning. BIOMEDICAL OPTICS EXPRESS, 13(2), 888–901. https://doi.org/10.1364/BOE.447392

Muthusamy, N., Williams, T. I., O'Toole, R., Brudvig, J. J., Adler, K. B., Weimer, J. M., … Ghashghaei, H. T. (2022, January 24). Phosphorylation-dependent proteome of Marcks in ependyma during aging and behavioral homeostasis in the mouse forebrain. GEROSCIENCE, Vol. 1. https://doi.org/10.1007/s11357-022-00517-3

Li, C., Moatti, A., Zhang, X., Ghashghaei, H. T., & Greenabum, A. (2021). Deep learning-based autofocus method enhances image quality in light-sheet fluorescence microscopy. BIOMEDICAL OPTICS EXPRESS, 12(8), 5214–5226. https://doi.org/10.1364/BOE.427099

Cai, Y., Zhang, X., Kovalsky, S. Z., Ghashghaei, H. T., & Greenbaum, A. (2021). Detection and classification of neurons and glial cells in the MADM mouse brain using RetinaNet. PLOS ONE, 16(9). https://doi.org/10.1371/journal.pone.0257426

Wu, J., Tian, W.-J., Liu, Y., Wan, H. J., Zheng, J., Wang, X., … Shen, Q. (2020). Ependyma-expressed CCN1 restricts the size of the neural stem cell pool in the adult ventricular-subventricular zone. EMBO JOURNAL, 39(5). https://doi.org/10.15252/embj.2019101679

Johnson, C. A., & Ghashghaei, H. T. (2020). Sp2 regulates late neurogenic but not early expansive divisions of neural stem cells underlying population growth in the mouse cortex. DEVELOPMENT, 147(4). https://doi.org/10.1242/dev.186056

Johnson, C., & Ghashghaei, T. (2020, February). The people behind the papers - Caroline Johnson and Troy Ghashghaei. DEVELOPMENT, Vol. 147. https://doi.org/10.1242/dev.188904

Muthusamy, N., Brumm, A., Zhang, X., Carmichael, S. T., & Ghashghaei, H. T. (2018). Foxj1 expressing ependymal cells do not contribute new cells to sites of injury or stroke in the mouse forebrain. SCIENTIFIC REPORTS, 8. https://doi.org/10.1038/s41598-018-19913-x

Brudvig, J. J., Cain, J. T., Sears, R. M., Schmidt-Grimminger, G. G., Wittchen, E. S., Adler, K. B., … Weimer, J. M. (2018). MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network. SCIENTIFIC REPORTS, 8. https://doi.org/10.1038/s41598-018-31578-0

Ehling, S., Butler, A., Thi, S., Ghashghaei, H. T., & Bäumer, W. (2018). To scratch an itch: Establishing a mouse model to determine active brain areas involved in acute histaminergic itch. IBRO Reports, 5, 67–73. https://doi.org/10.1016/J.IBROR.2018.10.002

Muthusamy, N., Zhang, X., Johnson, C. A., Yadav, P. N., & Ghashghaei, H. T. (2017). Developmentally defined forebrain circuits regulate appetitive and aversive olfactory learning. NATURE NEUROSCIENCE, 20(1), 20–23. https://doi.org/10.1038/nn.4452

Ren, Y., Ao, Y., Timothy M. O'Shea, Burda, J. E., Bernstein, A. M., Brumm, A. J., … Sofroniew, M. V. (2017). Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury. SCIENTIFIC REPORTS, 7. https://doi.org/10.1038/srep41122

Beattie, R., Postiglione, M. P., Burnett, L. E., Laukoter, S., Streicher, C., Pauler, F. M., … Hippenmeyer, S. (2017). Mosaic analysis with double markers reveals distinct sequential functions of Lgl1 in neural stem cells. Neuron (Cambridge, Mass.), 94(3), 517-. https://doi.org/10.1016/j.neuron.2017.04.012

Johnson, C. A., Wright, C. E., & Ghashghaei, H. T. (2017). Regulation of cytokinesis during corticogenesis: focus on the midbody. FEBS Letters, 591(24), 4009–4026. https://doi.org/10.1002/1873-3468.12676

Davis, A., Amin, N. M., Johnson, C., Bagley, K., Ghashghaei, H. T., & Nascone-Yoder, N. (2017). Stomach curvature is generated by left-right asymmetric gut morphogenesis. DEVELOPMENT, 144(8), 1477–1483. https://doi.org/10.1242/dev.143701

Dwyer, N. D., Chen, B., Chou, S.-J., Hippenmeyer, S., Nguyen, L., & Ghashghaei, H. T. (2016). Neural Stem Cells to Cerebral Cortex: Emerging Mechanisms Regulating Progenitor Behavior and Productivity. JOURNAL OF NEUROSCIENCE, 36(45), 11394–11401. https://doi.org/10.1523/jneurosci.2359-16.2016

Bain, L. E., Kirste, R., Johnson, C. A., Ghashghaei, H. T., Collazo, R., & Ivanisevic, A. (2016). Neurotypic cell attachment and growth on III-nitride lateral polarity structures. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 58, 1194–1198. https://doi.org/10.1016/j.msec.2015.09.084

Sai, K., Morioka, S., Takaesu, G., Muthusamy, N., Ghashghaei, H. T., Hanafusa, H., … Ninomiya-Tsuji, J. (2016). TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus. Journal of Cell Science, 129(9), 1855–1865. https://doi.org/10.1242/jcs.180505

Loziuk, P., Meier, F., Johnson, C., Ghashghaei, H. T., & Muddiman, D. C. (2016). TransOmic analysis of forebrain sections in Sp2 conditional knockout embryonic mice using IR-MALDESI imaging of lipids and LC-MS/MS label-free proteomics. Analytical and Bioanalytical Chemistry, 408(13), 3453–3474. https://doi.org/10.1007/s00216-016-9421-3

Rosen, E. P., Bokhart, M. T., Ghashghaei, H. T., & Muddiman, D. C. (2015). Influence of Desorption Conditions on Analyte Sensitivity and Internal Energy in Discrete Tissue or Whole Body Imaging by IR-MALDESI. Journal of The American Society for Mass Spectrometry, 26(6), 899–910. https://doi.org/10.1007/s13361-015-1114-1

Muthusamy, N., Sommerville, L. J., Moeser, A. J., Stumpo, D. J., Sannes, P., Adler, K., … Ghashghaei, H. T. (2015). MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging. AGING CELL, 14(5), 764–773. https://doi.org/10.1111/acel.12354

Hammad, M., Schmidt, S. L., Zhang, X., Bray, R., Frohlich, F., & Ghashghaei, H. T. (2015). Transplantation of GABAergic Interneurons into the Neonatal Primary Visual Cortex Reduces Absence Seizures in Stargazer Mice. CEREBRAL CORTEX, 25(9), 2970–2979. https://doi.org/10.1093/cercor/bhu094

Murlidharan, G., Corriher, T., Ghashghaei, H. T., & Asokan, A. (2015). Unique Glycan Signatures Regulate Adeno-Associated Virus Tropism in the Developing Brain. JOURNAL OF VIROLOGY, 89(7), 3976–3987. https://doi.org/10.1128/jvi.02951-14

Muthusamy, N., Vijayakumar, A., Cheng, G., Jr., & Ghashghaei, H. T. (2014). A Knock-in Foxj1(CreERT2:: GFP)Mouse for Recombination in Epithelial Cells with Motile Cilia. GENESIS, 52(4), 350–358. https://doi.org/10.1002/dvg.22753

Nehrenberg, D. L., Sheikh, A., & Ghashghaei, H. T. (2013). Identification of neuronal loci involved with displays of affective aggression in NC900 mice. BRAIN STRUCTURE & FUNCTION, 218(4), 1033–1049. https://doi.org/10.1007/s00429-012-0445-y

Liang, H., Xiao, G., Yin, H., Hippenmeyer, S., Horowitz, J. M., & Ghashghaei, H. T. (2013). Neural development is dependent on the function of specificity protein 2 in cell cycle progression. DEVELOPMENT, 140(3), 552–561. https://doi.org/10.1242/dev.085621

Liang, H., Hippenmeyer, S., & Ghashghaei, H. T. (2012). A Nestin-cre transgenic mouse is insufficient for recombination in early embryonic neural progenitors. Biology Open, 1(12), 1200–1203. https://doi.org/10.1242/bio.20122287

Jacquet, B. V., Muthusamy, N., Sommerville, L. J., Xiao, G., Liang, H., Zhang, Y., … Ghashghaei, H. T. (2011). Specification of a Foxj1-Dependent Lineage in the Forebrain Is Required for Embryonic-to-Postnatal Transition of Neurogenesis in the Olfactory Bulb. JOURNAL OF NEUROSCIENCE, 31(25), 9368–9382. https://doi.org/10.1523/jneurosci.0171-11.2011

Jacquet, B. V., Ruckart, P., & Ghashghaei, H. T. (2010). An Organotypic Slice Assay for High-Resolution Time-Lapse Imaging of Neuronal Migration in the Postnatal Brain. Journal of Visualized Experiments, (46). https://doi.org/10.3791/2486

Lim, J.-H., Piedrahita, J. A., Jackson, L., Ghashghaei, T., & Olby, N. J. (2010). Development of a Model of Sacrocaudal Spinal Cord Injury in Cloned Yucatan MiniPigs for Cellular Transplantation Research. CELLULAR REPROGRAMMING, 12(6), 689–697. https://doi.org/10.1089/cell.2010.0039

Jacquet, B. V., Patel, M., Iyengar, M., Liang, H., Therit, B., Salinas-Mondragon, R., … Ghashghaei, H. T. (2009). Analysis of neuronal proliferation, migration and differentiation in the postnatal brain using equine infectious anemia virus-based lentiviral vectors. GENE THERAPY, 16(8), 1021–1033. https://doi.org/10.1038/gt.2009.58

Nighot, P. K., Moeser, A. J., Ryan, K. A., Ghashghaei, T., & Blikslager, A. T. (2009). ClC-2 is required for rapid restoration of epithelial tight junctions in ischemic-injured murine jejunum. Experimental Cell Research, 315(1), 110–118. https://doi.org/10.1016/j.yexcr.2008.10.001

Moy, S. S., Ghashghaei, H. T., Nonneman, R. J., Weimer, J. M., Yokota, Y., Lee, D., … Anton, E. S. (2009). Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia. JOURNAL OF NEURODEVELOPMENTAL DISORDERS, 1(4), 302–312. https://doi.org/10.1007/s11689-009-9017-8

Jacquet, B. V., Salinas-Mondragon, R., Liang, H., Therit, B., Buie, J. D., Dykstra, M., … Ghashghaei, H. T. (2009). FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain. DEVELOPMENT, 136(23), 4021–4031. https://doi.org/10.1242/dev.041129

Ghashghaei, H. T., Lai, C., & Anton, E. S. (2007). [Review of Neuronal migration in the adult brain: are we there yet?]. NATURE REVIEWS NEUROSCIENCE, 8(2), 141–151. https://doi.org/10.1038/nrn2074

Yokota, Y., Ghashghaei, H. T., Han, C., Watson, H., Campbell, K. J., & Anton, E. S. (2007). Radial Glial Dependent and Independent Dynamics of Interneuronal Migration in the Developing Cerebral Cortex. PLoS ONE, 2(8), e794. https://doi.org/10.1371/journal.pone.0000794

Ghashghaei, H. T., Weimer, J. M., Schmid, R. S., Yokota, Y., McCarthy, K. D., Popko, B., & Anton, E. S. (2007). Reinduction of ErbB2 in astrocytes promotes radial glial progenitor identity in adult cerebral cortex. Genes & Development, 21(24), 3258–3271. https://doi.org/10.1101/gad.1580407

Ghashghaei, H. T., Hilgetag, C. C., & Barbas, H. (2007). Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala. NeuroImage, 34(3), 905–923. https://doi.org/10.1016/j.neuroimage.2006.09.046

Ghashghaei, H. T., Weber, J., Pevny, L., Schmid, R., Schwab, M. H., Lloyd, K. C. K., … Anton, E. S. (2006). The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone. Proceedings of the National Academy of Sciences, 103(6), 1930–1935. https://doi.org/10.1073/pnas.0510410103

Ghashghaei, T., Patel, M., Olsen, J., & Anton, E. (2005). 752. Equine Infectious Anemia Virus Pseudotyped with the Vesicular Stomatitis Virus G-Protein, Preferentially Targets Neural Precursors in the Adult Mouse Brain. Molecular Therapy, 11(Supplement 1), S292. https://doi.org/10.1016/j.ymthe.2005.07.293

Anton, E. S., Ghashghaei, H. T., Weber, J. L., McCann, C., Fischer, T. M., Cheung, I. D., … Lai, C. (2004). Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain. Nature Neuroscience, 7(12), 1319–1328. https://doi.org/10.1038/nn1345