Works (54)

Updated: May 4th, 2023 05:01

2023 article

Changes in metabolic landscapes shape divergent but distinct mutational signatures and cytotoxic consequences of redox stress

Degtyareva, N. P., Placentra, V. C., Gabel, S. A., Klimczak, L. J., Gordenin, D. A., Wagner, B. A., … Doetsch, P. W. (2023, April 20). NUCLEIC ACIDS RESEARCH, Vol. 4.

By: N. Degtyareva*, V. Placentra*, S. Gabel*, L. Klimczak*, D. Gordenin*, B. Wagner*, G. Buettner*, G. Mueller*, T. Smirnova, P. Doetsch*

Sources: Web Of Science, ORCID
Added: May 1, 2023

2021 article

EPR Oximetry with Nitroxides: Effects of Molecular Structure, pH, and Electrolyte Concentration

Voinov, M. A., Smirnova, T. I., & Smirnov, A. I. (2021, November 20). APPLIED MAGNETIC RESONANCE, Vol. 11.

By: M. Voinov n, T. Smirnova & A. Smirnov n

Sources: Web Of Science, ORCID
Added: November 20, 2021

2021 journal article

Integrative structural dynamics probing of the conformational heterogeneity in synaptosomal-associated protein 25

CELL REPORTS PHYSICAL SCIENCE, 2(11).

By: N. Saikia*, I. Yanez-Orozco*, R. Qiu, P. Hao, S. Milikisiyants, E. Ou n, G. Hamilton*, K. Weninger ...

Sources: Web Of Science, ORCID
Added: March 14, 2022

2021 journal article

Measuring plasma-generated center dot OH and O atoms in liquid using EPR spectroscopy and the non-selectivity of the HTA assay

JOURNAL OF PHYSICS D-APPLIED PHYSICS, 54(14).

By: B. Myers, P. Ranieri, T. Smirnova, P. Hewitt, D. Peterson, M. Quesada, E. Lenker, K. Stapelmann

author keywords: atmospheric pressure plasma jet; atomic oxygen; hydroxyl radicals; hydrogen peroxide; reactive oxygen species; plasma-liquid chemistry; EPR spectroscopy
Sources: Web Of Science, ORCID
Added: January 9, 2021

2020 journal article

Alternative Reactivity of Leucine 5-Hydroxylase Using an Olefin-Containing Substrate to Construct a Substituted Piperidine Ring

BIOCHEMISTRY, 59(21), 1961–1965.

By: L. Cha, S. Milikisiyants, M. Davidson, S. Xue*, T. Smirnova, A. Smirnov n, Y. Guo*, W. Chang

Sources: Web Of Science, ORCID
Added: June 22, 2020

2019 journal article

Dielectric and Electrostatic Properties of the Silica Nanoparticle-Water Interface by EPR of pH-Sensitive Spin Probes

JOURNAL OF PHYSICAL CHEMISTRY C, 123(49), 29972–29985.

By: V. Perelygin, M. Voinov, A. Marek, E. Ou n, J. Krim, D. Brenner, T. Smirnova, A. Smirnov n

Sources: Web Of Science, ORCID
Added: January 6, 2020

2019 article

EPR studies of bionanomaterials

ELECTRON MAGNETIC RESONANCE - APPLICATIONS IN PHYSICAL SCIENCES AND BIOLOGY, Vol. 50, pp. 129–159.

By: T. Smirnova & A. Smirnov

Sources: Web Of Science, ORCID
Added: November 18, 2019

2019 journal article

Effect of Silica Support on Electrostatics of Lipid Interfaces in Nano-Bio Hybrid Systems

Biophysical Journal, 116(3), 81a.

By: E. Ou, M. Voinov, A. Irving, A. Smirnov & T. Smirnova

Sources: Crossref, ORCID
Added: February 24, 2020

2019 review

Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

[Review of ]. BIOMOLECULES, 9(3).

By: U. Choi*, H. Sanabria*, T. Smirnova, M. Bowen* & K. Weninger

author keywords: dynamic configuration; free energy landscape; intrinsically disordered protein; IDP
Sources: Web Of Science, ORCID
Added: April 29, 2019

2018 journal article

Elucidating the Reaction Pathway of Decarboxylation-Assisted Olefination Catalyzed by a Mononuclear Non-Heme Iron Enzyme

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(45), 15190–15193.

By: C. Yu, Y. Tang*, L. Cha, S. Milikisiyants, T. Smirnova, A. Smirnov n, Y. Guo*, W. Chang

Sources: Web Of Science, ORCID
Added: December 10, 2018

2018 journal article

Silica-Supported Lipid Bilayers: Electrostatic Effects at Lipid Interfaces as Reported by Spin-Labeling EPR

Biophysical Journal, 114(3), 96a.

By: E. Ou, M. Voinov, A. Smirnov & T. Smirnova

Sources: Crossref, ORCID
Added: February 24, 2020

2018 journal article

Using Hyscore Spectroscopy of Nitroxides to Profile Water Content of Lipid Bilayers with 2 Å Spatial Resolution

Biophysical Journal, 114(3), 16a.

By: M. Chestnut n, S. Milikisiyants n, A. Koolivand n, M. Voynov, T. Smirnova & A. Smirnov n

Sources: Crossref, ORCID
Added: August 28, 2020

2017 journal article

Effects of Silica Support on Dynamics of Transmembrane Peptides and Effective p K a of Ionisable Sidechains

Biophysical Journal, 112(3), 175a.

By: E. Ou n, M. Voinov n, A. Smirnov n & T. Smirnova

Sources: Crossref, ORCID
Added: February 24, 2020

2017 journal article

Glycol Chitosan Engineered Autoregenerative Antioxidant Significantly Attenuates Pathological Damages in Models of Age-Related Macular Degeneration

ACS Nano, 11(5), 4669–4685.

By: R. Mitra*, R. Gao*, M. Zheng*, M. Wu*, M. Voinov, A. Smirnov n, T. Smirnova, K. Wang*, S. Chavala*, Z. Han*

author keywords: age-related macular degeneration; cerium oxide nanoparticles; antioxidant; reactive oxygen species; laser-induced choroidal neovascularization
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Oligomeric Structure of Anabaena Sensory Rhodopsin in a Lipid Bilayer Environment by Combining Solid-State NMR and Long-range DEER Constraints

JOURNAL OF MOLECULAR BIOLOGY, 429(12), 1903–1920.

By: S. Milikisiyants, S. Wang*, R. Munro*, M. Donohue, M. Ward*, D. Bolton*, L. Brown*, T. Smirnova, V. Ladizhansky*, A. Smirnov n

author keywords: double electron electron resonance (DEER); site-directed spin labeling; solid-state NMR; paramagnetic relaxation enhancement; membrane protein structure
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Oxidation of pyrrole by dehaloperoxidase-hemoglobin: chemoenzymatic synthesis of pyrrolin-2-ones

CATALYSIS SCIENCE & TECHNOLOGY, 7(14), 3104–3118.

By: N. McCombs, T. Smirnova & R. Ghiladi

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Synthesis of New Mixed-Metal Ammonium Vanadates: Cation Order versus Disorder, and Optical and Photocatalytic Properties

CRYSTAL GROWTH & DESIGN, 16(10), 5762–5770.

By: L. Luo, E. Ou n, T. Smirnova & P. Maggard

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

The Hydroxyl Radical is a Critical Intermediate in the Voltammetric Detection of Hydrogen Peroxide

Journal of the American Chemical Society, 138(8), 2516–2519.

By: J. Roberts, M. Voinov, A. Schmidt, T. Smirnova & L. Sombers

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

smFRET and DEER Distance Measurements as Applied to Disordered and Structured Proteins

Biophysical Journal, 110(3), 559a.

By: K. Weninger, R. Qiu n, E. Ou n, S. Milikisiyants n, H. Sanabria* & T. Smirnova

Sources: Crossref, ORCID
Added: February 5, 2020

2015 journal article

Determining Oligomeric Order of a Membrane Protein by Double Electron-Electron Resonance Spectroscopy

Biophysical Journal, 108(2), 93a.

By: S. Milikisiyants n, S. Wang*, R. Munro*, M. Donohue n, L. Brown*, T. Smirnova, V. Ladizhansky*, A. Smirnov n

Sources: Crossref, ORCID
Added: February 24, 2020

2015 journal article

Ferromagnetic coupling in d(1)-d(3) linear oxido-bridged heterometallic complexes: ground-state models of metal-to-metal charge transfer excited states

DALTON TRANSACTIONS, 44(43), 18937–18944.

By: T. Huang, X. Wu, X. Song, H. Xu n, T. Smirnova, W. Weare, R. Sommer

Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Manganese-Vanadate Hybrids: Impact of Organic Ligands on Their Structures, Thermal Stabilities, Optical Properties, and Photocatalytic Activities

INORGANIC CHEMISTRY, 54(15), 7388–7401.

By: L. Luo, Y. Zeng n, L. Li, Z. Luo*, T. Smirnova & P. Maggard

Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

“Snorkeling” of the Charged Sidechain of a Transmembrane Peptide as Directly Observed by Double Electron-Electron Resonance Experiment

Biophysical Journal, 108(2), 203a.

By: M. Donohue n, M. Voynov, S. Milikisiyants n, A. Smirnov n & T. Smirnova

Sources: Crossref, ORCID
Added: August 28, 2020

2014 journal article

Copper-Organic/Octamolybdates: Structures, Bandgap Sizes, and Photocatalytic Activities

Inorganic Chemistry, 53(7), 3464–3470.

By: L. Luo, H. Lin, L. Li n, T. Smirnova & P. Maggard

Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018

2014 journal article

Identification of free radicals in pyrolysis oil and their impact on bio-oil stability

RSC ADVANCES, 4(56), 29840–29846.

By: J. Meng, T. Smirnova, X. Song, A. Moore, X. Ren n, S. Kelley, S. Park, D. Tilotta

Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Profiling the Dielectric Constant at the Membrane-Peptide Interface using Ionizable EPR Probes

Biophysical Journal, 106(2), 508a.

By: M. Donohue n, M. Voynov, A. Smirnov n & T. Smirnova

Sources: Crossref, ORCID
Added: February 24, 2020

2014 journal article

Structure, Dynamics, and Electrostatic Effects on Membrane Binding of Nod Peptides

Biophysical Journal, 106(2), 295a.

By: M. Quinones n, V. Bankaitis* & T. Smirnova

Sources: Crossref, ORCID
Added: February 24, 2020

2013 journal article

Isoprenoid Biosynthesis: Ferraoxetane or Allyl Anion Mechanism for IspH Catalysis?

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 52(25), 6522–6525.

By: J. Li*, K. Wang*, T. Smirnova, R. Khade*, Y. Zhang* & E. Oldfield*

author keywords: biosynthesis; enzyme catalysis; iron-sulfur cluster; metalloproteins; terpenes
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Molecular pH Probes at a Protein-Lipid Interface: Assessment of Local Dielectric Environment for Transmembrane Peptide

Biophysical Journal, 104(2), 373a.

By: M. Donohue n, M. Voynov, A. Smirnov n & T. Smirnova

Sources: Crossref, ORCID
Added: February 24, 2020

2013 journal article

The UDP-diacylglucosamine Pyrophosphohydrolase LpxH in Lipid A Biosynthesis Utilizes Mn2+ Cluster for Catalysis

JOURNAL OF BIOLOGICAL CHEMISTRY, 288(38), 26987–27001.

By: H. Young*, M. Donohue, T. Smirnova, A. Smirnov n & P. Zhou*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Tyrosyl Radicals in Dehaloperoxidase

Journal of Biological Chemistry, 288(46), 33470–33482.

By: R. Dumarieh n, J. D'Antonio n, A. Deliz-Liang n, T. Smirnova, D. Svistunenko* & R. Ghiladi

author keywords: Hemoglobin; Iron; Peroxidase; Radicals; Tyrosine; Compound ES; Compound I; Compound II; Dehaloperoxidase; Ferryl
Sources: Crossref, ORCID
Added: February 24, 2020

2013 journal article

Tyrosyl radicals in dehaloperoxidase how nature deals with evolving an oxygen-binding globin to a biologically relevant peroxidase

Journal of Biological Chemistry, 288(46), 33470–33482.

By: R. Dumarieh, J. D'Antonio, A. Deliz-Liang, T. Smirnova, D. Svistunenko & R. Ghiladi

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Probing Dielectric and Hydrogen Bonding Gradients in Biological Membranes

Biophysical Journal, 102(3), 414a.

By: T. Smirnova, M. Voynov, O. Poluektov* & A. Smirnov n

Sources: Crossref, ORCID
Added: February 24, 2020

2011 journal article

An ENDOR and HYSCORE Investigation of a Reaction Intermediate in IspG (GcpE) Catalysis

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(22), 8400–8403.

By: W. Wang*, K. Wang*, J. Li*, S. Nellutla, T. Smirnova & E. Oldfield*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Pyridine Inhibitor Binding to the 4Fe-4S Protein A. aeolicus IspH (LytB): A HYSCORE Investigation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(17), 6525–6528.

By: W. Wang*, J. Li*, K. Wang, T. Smirnova & E. Oldfield*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution

MOLECULAR BIOLOGY OF THE CELL, 22(6), 892–905.

By: G. Schaaf*, M. Dynowski*, C. Mousley*, S. Shah*, P. Yuan*, E. Winklbauer*, M. Campos*, K. Trettin* ...

Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Role of Electrostatic and Hydrogen Bonding Environment in Sequestering Lipids from Membranes Into the Sec14 Protein Cavity

Biophysical Journal, 100(3), 552a–553a.

By: T. Smirnova, T. Chadwick, V. Bankaitis, G. Schaaf, O. Poluektov & A. Smirnov

Sources: Crossref, ORCID
Added: February 24, 2020

2011 journal article

Surface-Mediated Production of Hydroxyl Radicals as a Mechanism of Iron Oxide Nanoparticle Biotoxicity

Journal of the American Chemical Society, 133(1), 35–41.

By: M. Voinov, J. Pagán n, E. Morrison n, T. Smirnova & A. Smirnov n

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2010 journal article

Heterogeneous Dielectric and Hydrogen Bonding Environment of Transmembrane Peptides

Biophysical Journal, 98(3), 87a.

By: T. Smirnova, M. Voynov, O. Poluektov* & A. Smirnov n

Sources: Crossref, ORCID
Added: February 24, 2020

2010 journal article

Spectroscopic and Mechanistic Investigations of Dehaloperoxidase B fromAmphitrite ornata

Biochemistry, 49(31), 6600–6616.

By: J. D’Antonio n, E. D’Antonio n, M. Thompson, E. Bowden, S. Franzen, T. Smirnova, R. Ghiladi

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Characterization of Dehaloperoxidase Compound ES and Its Reactivity with Trihalophenols†

Biochemistry, 48(5), 995–1005.

By: J. Feducia, R. Dumarieh, L. Gilvey, T. Smirnova, S. Franzen & R. Ghiladi

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Membrane insertion of peptides mimicking E2 domain of Sindbis virus is modulated by cholesterol

Biophysical Journal, 96(3), 389a–390a.

By: T. Chadwick n, G. Rabah, B. Davies n & T. Smirnova

Sources: Crossref, ORCID
Added: February 24, 2020

2009 journal article

Spectroscopic Probes of the Reactive Intermediates of Dehaloperoxidase from Amphitrite ornata

Biophysical Journal, 96(3), 437a.

By: R. Ghiladi, R. Dumarieh n, M. Thompson n, Z. Wang n, T. Smirnova & S. Franzen

Sources: Crossref, ORCID
Added: February 24, 2020

2009 journal article

Substrate binding triggers a switch in the iron coordination in dehaloperoxidase from Amphitrite Ornate

Biophysical Journal, 96(3), 437a.

By: T. Smirnova, M. Davis n, R. Weber* & S. Franzen

Sources: Crossref, ORCID
Added: February 24, 2020

2008 journal article

Characterization of magnetic and electronic properties of trimetallic nitride endohedral fullerenes by SQUID magnetometry and electron paramagnetic resonance

CHEMICAL PHYSICS LETTERS, 453(4-6), 233–237.

By: T. Smirnova, A. Smirnov n, T. Chadwick & K. Walker*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Substrate binding triggers a switch in the iron coordination in dehaloperoxidase from Amphitrite ornata: HYSCORE experiments

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(7), 2128-+.

By: T. Smirnova, R. Weber n, M. Davis n & S. Franzen

Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Binding of MRI contrast agents to albumin: a high-field EPR study

APPLIED MAGNETIC RESONANCE, 31(3-4), 431–446.

By: T. Smirnova

Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Geometry of hydrogen bonds formed by lipid bilayer nitroxide probes: A high-frequency pulsed ENDOR/EPR study

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129(12), 3476-+.

By: T. Smirnova, A. Smirnov n, S. Paschenko n & O. Poluektov n

Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Local polarity and hydrogen bonding inside the Sec14p phospholipid-binding cavity: High-field multi-frequency electron paramagnetic resonance studies

BIOPHYSICAL JOURNAL, 92(10), 3686–3695.

By: T. Smirnova, T. Chadwick, M. Voinov, O. Poluektov*, J. Tol*, A. Ozarowski*, G. Schaaf*, M. Ryan*, V. Bankaitis*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Cryogen-free superconducting magnet system for multifrequency electron paramagnetic resonance up to 12.1T

Review of Scientific Instruments, 77(3), 035108.

By: A. Smirnov, T. Smirnova, R. MacArthur, J. Good & R. Hall

Sources: Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2006 journal article

The chemistry of phospholipid binding by the Saccharomyces cerevisiae phosphatidylinositol transfer protein Sec14p as determined by EPR spectroscopy

JOURNAL OF BIOLOGICAL CHEMISTRY, 281(46), 34897–34908.

By: T. Smirnova, T. Chadwick, R. MacArthur, O. Poluektov*, L. Song*, M. Ryan*, G. Schaaf*, V. Bankaitis*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2003 journal article

Dynamic molecular oxygen accessibility to a buried Mn2+ protein site: A high-field EPR experiment

JOURNAL OF PHYSICAL CHEMISTRY B, 107(29), 7212–7215.

By: T. Smirnova & A. Smirnov

Sources: Web Of Science, ORCID
Added: August 6, 2018

2001 journal article

Resolving domains of interdigitated phospholipid membranes with 95 GHz spin labeling EPR

APPLIED MAGNETIC RESONANCE, 21(3-4), 453–467.

By: A. Smirnov & T. Smirnova

Sources: Web Of Science, ORCID
Added: August 6, 2018

1998 journal article

Multi-frequency EPR determination of zero field splitting of high spin species in liquids: Gd(III) chelates in water

Molecular Physics, 95(6), 1325–1332.

By: R. Clarkson*, A. Smirnov*, T. Smirnova, H. Kang*, R. Belford*, K. Earle*, J. Freed*

Sources: Crossref, ORCID
Added: August 28, 2020

Employment

Updated: August 11th, 2021 19:08

North Carolina State University Raleigh, North Carolina, US
Associate Professor Chemistry

Education

Updated: September 30th, 2022 17:47

University of Illinois Urbana-Champaign Urbana, Illinois, US
PhD Chemistry

1997 - 2000

University of Illinois Urbana-Champaign Urbana, Illinois, US
Postdoctoral Fellow