Tatyana I. Smirnova

BPS2025 - Local electrostatics of transmembrane domains by spin labeling EPR

Smirnova, T. I., Voinov, M. A., Milikisiyants, S., Cook, G. A., & Smirnov, A. I. (2025, February 1). Biophysical Journal, Vol. 2.

A TriAdj-Adjuvanted Chlamydia trachomatis CPAF Protein Vaccine Is Highly Immunogenic in Pigs

Proctor, J., Stadler, M., Cortes, L. M., Brodsky, D., Poisson, L., Gerdts, V., … Käser, T. (2024, April 16). Vaccines, Vol. 12.

Measuring local pH at interfaces from molecular tumbling: A concept for designing EPR-active pH-sensitive labels and probes

Voinov, M. A., Nunn, N., Rana, R., Davidsson, A., Smirnov, A. I., & Smirnova, T. I. (2024, January 1). Organic & Biomolecular Chemistry, Vol. 4.

Changes in metabolic landscapes shape divergent but distinct mutational signatures and cytotoxic consequences of redox stress

Degtyareva, N. P., Placentra, V. C., Gabel, S. A., Klimczak, L. J., Gordenin, D. A., Wagner, B. A., … Doetsch, P. W. (2023, April 20). Nucleic Acids Research, Vol. 4.

EPR Oximetry with Nitroxides: Effects of Molecular Structure, pH, and Electrolyte Concentration

Voinov, M. A., Smirnova, T. I., & Smirnov, A. I. (2021, November 20). Applied Magnetic Resonance, Vol. 11.

Integrative structural dynamics probing of the conformational heterogeneity in synaptosomal-associated protein 25

Saikia, N., Yanez-Orozco, I. S., Qiu, R., Hao, P., Milikisiyants, S., Ou, E., … Ding, F. (2021, October 19). Cell Reports Physical Science, Vol. 11.

Measuring plasma-generated ^· OH and O atoms in liquid using EPR spectroscopy and the non-selectivity of the HTA assay

Myers, B., Ranieri, P., Smirnova, T., Hewitt, P., Peterson, D., Quesada, M. H., … Stapelmann, K. (2021, January 8). Journal of Physics D Applied Physics, Vol. 54, p. 145202.

Alternative Reactivity of Leucine 5-Hydroxylase Using an Olefin-Containing Substrate to Construct a Substituted Piperidine Ring

Cha, L., Milikisiyants, S., Davidson, M., Xue, S., Smirnova, T., Smirnov, A., … Chang, W.-chen. (2020, May 13). Biochemistry, Vol. 59, pp. 1961–1965.

Dielectric and Electrostatic Properties of the Silica Nanoparticle–Water Interface by EPR of pH-Sensitive Spin Probes

Perelygin, V., Voinov, M. A., Marek, A., Ou, E., Krim, J., Brenner, D., … Smirnov, A. I. (2019, November 13). The Journal of Physical Chemistry C, Vol. 123, pp. 29972–29985.

EPR studies of bionanomaterials

Smirnova, T. I., & Smirnov, A. I. (2019, January 1). Experimental Methods in the Physical Sciences, Vol. 50, pp. 129–159.

Effect of Silica Support on Electrostatics of Lipid Interfaces in Nano-Bio Hybrid Systems

Biophysical Journal, 116(3), 81a.

Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

Choi, U., Sanabria, H., Smirnova, T., Bowen, M., & Weninger, K. (2019, March 22). Biomolecules, Vol. 9.

Elucidating the Reaction Pathway of Decarboxylation-Assisted Olefination Catalyzed by a Mononuclear Non-Heme Iron Enzyme

Yu, C.-P., Tang, Y., Cha, L., Milikisiyants, S., Smirnova, T. I., Smirnov, A. I., … Chang, W.-chen. (2018, October 30). Journal of the American Chemical Society, Vol. 140, pp. 15190–15193.

Silica-Supported Lipid Bilayers: Electrostatic Effects at Lipid Interfaces as Reported by Spin-Labeling EPR

Biophysical Journal, 114(3), 96a.

Using Hyscore Spectroscopy of Nitroxides to Profile Water Content of Lipid Bilayers with 2 Å Spatial Resolution

Biophysical Journal, 114(3), 16a.

Effects of Silica Support on Dynamics of Transmembrane Peptides and Effective p K a of Ionisable Sidechains

Biophysical Journal, 112(3), 175a.

Glycol Chitosan Engineered Autoregenerative Antioxidant Significantly Attenuates Pathological Damages in Models of Age-Related Macular Degeneration

ACS Nano, 11(5), 4669–4685.

Oligomeric Structure of Anabaena Sensory Rhodopsin in a Lipid Bilayer Environment by Combining Solid-State NMR and Long-range DEER Constraints

Milikisiyants, S., Wang, S., Munro, R. A., Donohue, M., Ward, M. E., Bolton, D., … Smirnov, A. I. (2017, May 10). Journal of Molecular Biology, Vol. 429, pp. 1903–1920.

Oxidation of pyrrole by dehaloperoxidase-hemoglobin: chemoenzymatic synthesis of pyrrolin-2-ones

McCombs, N. L., Smirnova, T., & Ghiladi, R. A. (2017, January 1). Catalysis Science & Technology, Vol. 7, pp. 3104–3118.

Synthesis of New Mixed-Metal Ammonium Vanadates: Cation Order versus Disorder, and Optical and Photocatalytic Properties

Luo, L., Ou, E., Smirnova, T. I., & Maggard, P. A. (2016, September 6). Crystal Growth & Design, Vol. 16, pp. 5762–5770.

The Hydroxyl Radical is a Critical Intermediate in the Voltammetric Detection of Hydrogen Peroxide

Journal of the American Chemical Society, 138(8), 2516–2519.

smFRET and DEER Distance Measurements as Applied to Disordered and Structured Proteins

Biophysical Journal, 110(3), 559a.

Determining Oligomeric Order of a Membrane Protein by Double Electron-Electron Resonance Spectroscopy

Biophysical Journal, 108(2), 93a.

Ferromagnetic coupling in d¹–d³ linear oxido-bridged heterometallic complexes: ground-state models of metal-to-metal charge transfer excited states

Huang, T., Wu, X., Song, X., Xu, H., Smirnova, T. I., Weare, W. W., & Sommer, R. D. (2015, January 1). Dalton Transactions, Vol. 44, pp. 18937–18944.

Manganese–Vanadate Hybrids: Impact of Organic Ligands on Their Structures, Thermal Stabilities, Optical Properties, and Photocatalytic Activities

Luo, L., Zeng, Y., Li, L., Luo, Z., Smirnova, T. I., & Maggard, P. A. (2015, July 23). Inorganic Chemistry, Vol. 54, pp. 7388–7401.

“Snorkeling” of the Charged Sidechain of a Transmembrane Peptide as Directly Observed by Double Electron-Electron Resonance Experiment

Biophysical Journal, 108(2), 203a.

Copper-Organic/Octamolybdates: Structures, Bandgap Sizes, and Photocatalytic Activities

Inorganic Chemistry, 53(7), 3464–3470.

Identification of free radicals in pyrolysis oil and their impact on bio-oil stability

Meng, J., Smirnova, T. I., Song, X., Moore, A., Ren, X., Kelley, S., … Tilotta, D. (2014, January 1). RSC Advances, Vol. 4, pp. 29840–29846.

Profiling the Dielectric Constant at the Membrane-Peptide Interface using Ionizable EPR Probes

Biophysical Journal, 106(2), 508a.

Structure, Dynamics, and Electrostatic Effects on Membrane Binding of Nod Peptides

Biophysical Journal, 106(2), 295a.

Isoprenoid Biosynthesis: Ferraoxetane or Allyl Anion Mechanism for IspH Catalysis?

Li, J., Wang, K., Smirnova, T. I., Khade, R. L., Zhang, Y., & Oldfield, E. (2013, May 6). Angewandte Chemie International Edition, Vol. 52, pp. 6522–6525.

Molecular pH Probes at a Protein-Lipid Interface: Assessment of Local Dielectric Environment for Transmembrane Peptide

Biophysical Journal, 104(2), 373a.

The UDP-diacylglucosamine Pyrophosphohydrolase LpxH in Lipid A Biosynthesis Utilizes Mn2+ Cluster for Catalysis

Young, H. E., Donohue, M. P., Smirnova, T. I., Smirnov, A. I., & Zhou, P. (2013, July 30). Journal of Biological Chemistry, Vol. 288, pp. 26987–27001.

Tyrosyl Radicals in Dehaloperoxidase

Journal of Biological Chemistry, 288(46), 33470–33482.

Tyrosyl radicals in dehaloperoxidase how nature deals with evolving an oxygen-binding globin to a biologically relevant peroxidase

Journal of Biological Chemistry, 288(46), 33470–33482.

Probing Dielectric and Hydrogen Bonding Gradients in Biological Membranes

Biophysical Journal, 102(3), 414a.

An ENDOR and HYSCORE Investigation of a Reaction Intermediate in IspG (GcpE) Catalysis

Wang, W., Wang, K., Li, J., Nellutla, S., Smirnova, T. I., & Oldfield, E. (2011, May 16). Journal of the American Chemical Society, Vol. 133, pp. 8400–8403.

Pyridine Inhibitor Binding to the 4Fe-4S Protein A. aeolicus IspH (LytB): A HYSCORE Investigation

Wang, W., Li, J., Wang, K., Smirnova, T. I., & Oldfield, E. (2011, April 12). Journal of the American Chemical Society, Vol. 133, pp. 6525–6528.

Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution

Schaaf, G., Dynowski, M., Mousley, C. J., Shah, S. D., Yuan, P., Winklbauer, E. M., … Bankaitis, V. A. (2011, January 20). Molecular Biology of the Cell, Vol. 22, pp. 892–905.

Role of Electrostatic and Hydrogen Bonding Environment in Sequestering Lipids from Membranes Into the Sec14 Protein Cavity

Biophysical Journal, 100(3), 552a–553a.

Heterogeneous Dielectric and Hydrogen Bonding Environment of Transmembrane Peptides

Biophysical Journal, 98(3), 87a.

Spectroscopic and Mechanistic Investigations of Dehaloperoxidase B fromAmphitrite ornata

Biochemistry, 49(31), 6600–6616.

Surface-Mediated Production of Hydroxyl Radicals as a Mechanism of Iron Oxide Nanoparticle Biotoxicity

Journal of the American Chemical Society, 133(1), 35–41.

Characterization of Dehaloperoxidase Compound ES and Its Reactivity with Trihalophenols†

Biochemistry, 48(5), 995–1005.

Membrane insertion of peptides mimicking E2 domain of Sindbis virus is modulated by cholesterol

Chadwick, T. G., Rabah, G. A., Davies, B. R., & Smirnova, T. I. (2009, February 1). Biophysical Journal, Vol. 96, pp. 389a–390a.

Spectroscopic Probes of the Reactive Intermediates of Dehaloperoxidase from Amphitrite ornata

Biophysical Journal, 96(3), 437a.

Substrate binding triggers a switch in the iron coordination in dehaloperoxidase from Amphitrite Ornate

Biophysical Journal, 96(3), 437a.

Characterization of magnetic and electronic properties of trimetallic nitride endohedral fullerenes by SQUID magnetometry and electron paramagnetic resonance

Smirnova, T. I., Smirnov, A. I., Chadwick, T. G., & Walker, K. L. (2008, January 20). Chemical Physics Letters, Vol. 453, pp. 233–237.

Substrate Binding Triggers a Switch in the Iron Coordination in Dehaloperoxidase from Amphitrite ornata:  HYSCORE Experiments

Smirnova, T. I., Weber, R. T., Davis, M. F., & Franzen, S. (2008, January 25). Journal of the American Chemical Society, Vol. 130, p. 2128-.

Binding of MRI contrast agents to albumin: a high-field EPR study

Smirnova, T. I. (2007, September 1). Applied Magnetic Resonance, Vol. 31, pp. 431–446.

Geometry of Hydrogen Bonds Formed by Lipid Bilayer Nitroxide Probes:  A High-Frequency Pulsed ENDOR/EPR Study

Smirnova, T. I., Smirnov, A. I., Paschenko, S. V., & Poluektov, O. G. (2007, March 1). Journal of the American Chemical Society, Vol. 129, pp. 3476–3477.

Local Polarity and Hydrogen Bonding Inside the Sec14p Phospholipid-Binding Cavity: High-Field Multi-Frequency Electron Paramagnetic Resonance Studies

Smirnova, T. I., Chadwick, T. G., Voinov, M. A., Poluektov, O., Tol, J., Ozarowski, A., … Bankaitis, V. A. (2007, February 26). Biophysical Journal, Vol. 92, pp. 3686–3695.

Cryogen-free superconducting magnet system for multifrequency electron paramagnetic resonance up to 12.1T

Review of Scientific Instruments, 77(3), 035108.

The Chemistry of Phospholipid Binding by the Saccharomyces cerevisiae Phosphatidylinositol Transfer Protein Sec14p as Determined by EPR Spectroscopy

Smirnova, T. I., Chadwick, T. G., MacArthur, R., Poluektov, O., Song, L., Ryan, M. M., … Bankaitis, V. A. (2006, September 23). Journal of Biological Chemistry, Vol. 281, pp. 34897–34908.

Dynamic Molecular Oxygen Accessibility to a Buried Mn²⁺ Protein Site:  A High-Field EPR Experiment

Smirnova, T. I., & Smirnov, A. I. (2003, July 1). The Journal of Physical Chemistry B, Vol. 107, pp. 7212–7215.

Resolving domains of interdigitated phospholipid membranes with 95 GHz spin labeling EPR

Smirnov, A. I., & Smirnova, T. I. (2001, December 1). Applied Magnetic Resonance, Vol. 21, pp. 453–467.

Multi-frequency EPR determination of zero field splitting of high spin species in liquids: Gd(III) chelates in water

Molecular Physics, 95(6), 1325–1332.