Tyler John Michael Jordan

2024 journal article

Anti-NC16A IgA from Patients with Linear IgA Bullous Dermatosis Induce Neutrophil-Dependent Subepidermal Blistering in Mice

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 144(1).

By: K. Jing*, T. Jordan n, N. Li, S. Burette, B. Yang*, M. Marinkovich*, L. Diaz, P. Googe ...

TL;DR: It is shown that passive transfer of patient-derived anti-NC16A IgA induce clinical and histologic LABD pathology in humanized NC16A mice that are reconstituted locally or systemically with human neutrophils, and the importance of neutrophil-mediated tissue injury in LABd disease physiology is corroborated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: January 16, 2024

2023 journal article

The Eotaxin-1/CCR3 Axis and Matrix Metalloproteinase-9 Are Critical in Anti-NC16A IgE-Induced Bullous Pemphigoid

JOURNAL OF IMMUNOLOGY, 211(8), 1216–1223.

TL;DR: The eotaxin-1/CCR3 axis and MMP-9 are established as key players in anti-NC16A IgE-induced BP and candidate therapeutic targets for future drug development and testing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: March 11, 2024

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