Tyler Lee Harris
Works (4)
Updated: July 5th, 2023 15:45
2017 journal article
Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria
BIOORGANIC & MEDICINAL CHEMISTRY, 25(20), 5749–5753.
MeSH headings : Acinetobacter baumannii / drug effects; Adjuvants, Pharmaceutic / chemistry; Adjuvants, Pharmaceutic / pharmacology; Colistin / pharmacology; Drug Resistance, Bacterial / drug effects; Drug Resistance, Bacterial / genetics; Escherichia coli / drug effects; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Gram-Negative Bacteria / drug effects; Klebsiella pneumoniae / drug effects; Microbial Sensitivity Tests; Polymyxins / pharmacology; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Gold nanoparticles to improve HIV drug delivery
FUTURE MEDICINAL CHEMISTRY, 7(9), 1097–1107.
MeSH headings : Animals; Anti-HIV Agents / administration & dosage; Anti-HIV Agents / chemical synthesis; Anti-HIV Agents / chemistry; Brain / metabolism; Drug Carriers / chemistry; Endothelial Cells / cytology; Endothelial Cells / drug effects; Endothelial Cells / metabolism; Female; Gold / chemistry; HIV Core Protein p24 / antagonists & inhibitors; HIV Core Protein p24 / metabolism; HIV Infections / drug therapy; HIV-1 / physiology; Humans; Leukocytes, Mononuclear / cytology; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / metabolism; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Metal Nanoparticles / ultrastructure; Mice; Mice, Inbred BALB C; Raltegravir Potassium / administration & dosage; Raltegravir Potassium / chemical synthesis; Raltegravir Potassium / chemistry; Tissue Distribution; Virus Replication / drug effects
www.ncbi.nlm.nih.gov (repository)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Small Molecule Downregulation of PmrAB Reverses Lipid A Modification and Breaks Colistin Resistance
ACS CHEMICAL BIOLOGY, 9(1), 122–127.
MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Colistin / chemistry; Colistin / pharmacology; Down-Regulation / drug effects; Drug Resistance, Multiple, Bacterial / drug effects; Gram-Negative Bacteria / drug effects; Gram-Negative Bacteria / genetics; Gram-Negative Bacteria / metabolism; Gram-Negative Bacterial Infections / drug therapy; Humans; Lipid A / metabolism; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology; Transcription Factors / genetics
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Potent Small-Molecule Suppression of Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(45), 11254–11257.
author keywords: 2-aminoimidazoles; adjuvants; antibiotics; antibiotic resistance; MRSA
MeSH headings : Anti-Bacterial Agents / pharmacology; Drug Resistance; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Oxacillin / pharmacology
Source: Web Of Science
Added: August 6, 2018
