Teresa Leavens

Also known as: Teresa Cheek Leavens

https://orcid.org/0000-0001-7611-4096

Works (15)

Updated: July 15th, 2023 21:14
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2014 journal article

Development of a physiologically based pharmacokinetic model for flunixin in cattle (Bos taurus)

FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 31(9), 1506–1521.

By: T. Leavens n , L. Tell *, L. Kissell n, G. Smith n , D. Smith *, S. Wagner*, W. Shelver *, H. Wu  n ...

co-author countries: United States of America 🇺🇸
author keywords: flunixin; PBPK models; withdrawal intervals; route of administration; cattle (Bos taurus)
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle / blood; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Drug Residues; Liver / chemistry; Liver / metabolism; Milk / chemistry; Models, Biological; Sensitivity and Specificity; Software; Uncertainty
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Use of population pharmacokinetic modeling and Monte Carlo simulation to capture individual animal variability in the prediction of flunixin withdrawal times in cattle

Journal of Veterinary Pharmacology and Therapeutics, 36(3), 248–257.

By: H. Wu  n, R. Baynes n, T. Leavens n , L. Tell * & J. Riviere*

co-author countries: United States of America 🇺🇸
MeSH headings : Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Cattle / blood; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / pharmacokinetics; Computer Simulation; Drug Administration Routes; Drug Residues / pharmacokinetics; Female; Liver / metabolism; Male; Models, Biological; Monte Carlo Method
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Acute vascular effects of nanoparticle infusion in isolated perfused skin

Nanomedicine: Nanotechnology, Biology and Medicine, 8(4), 428–431.

By: J. Riviere n, T. Leavens n , J. Brooks n & N. Monteiro-Riviere n 

co-author countries: United States of America 🇺🇸

Contributors: J. Riviere n, T. Leavens n , J. Brooks n & N. Monteiro-Riviere n 

author keywords: Nanoparticles; Vascular toxicity; In vitro; Biodistribution
MeSH headings : Animals; Female; Perfusion; Quantum Dots; Skin / blood supply; Skin / pathology; Skin / physiopathology; Sus scrofa; Vascular Resistance / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 35(2), 121–131.

By: T. Leavens n , L. Tell *, K. Clothier*, R. Griffith*, R. Baynes n & J. Riviere n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Computer Simulation; Disaccharides / blood; Disaccharides / pharmacokinetics; Goats / blood; Goats / metabolism; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Models, Biological; Sensitivity and Specificity; Software; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

In vitro biodistribution of silver nanoparticles in isolated perfused porcine skin flaps

JOURNAL OF APPLIED TOXICOLOGY, 32(11), 913–919.

By: T. Leavens n , N. Monteiro-Riviere n , A. Inman n, J. Brooks n, S. Oldenburg* & J. Riviere n

co-author countries: United States of America 🇺🇸

Contributors: T. Leavens n , N. Monteiro-Riviere n , A. Inman n, J. Brooks n, S. Oldenburg* & J. Riviere n

author keywords: silver nanoparticles; biodistribution; skin
MeSH headings : Animals; Metal Nanoparticles / chemistry; Nanoparticles / chemistry; Perfusion; Silver / chemistry; Silver / pharmacokinetics; Skin / metabolism; Swine / metabolism; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats

AMERICAN JOURNAL OF VETERINARY RESEARCH, 73(10), 1634–1640.

By: J. Romanet*, G. Smith* , T. Leavens* , R. Baynes*, S. Wetzlich, J. Riviere*, L. Tell

MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Disaccharides / blood; Disaccharides / pharmacokinetics; Female; Goats / blood; Goats / metabolism; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Injections, Subcutaneous / veterinary; Male; Tandem Mass Spectrometry / veterinary; Time Factors; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

The Toxicology Education Summit: Building the Future of Toxicology Through Education

TOXICOLOGICAL SCIENCES, 127(2), 331–338.

By: A. Barchowsky *, L. Buckley*, G. Carlson*, V. Fitsanakis*, S. Ford*, M. Genter *, D. Germolec*, T. Leavens n  ...

co-author countries: United States of America 🇺🇸
author keywords: toxicology; education
MeSH headings : Cooperative Behavior; Curriculum / trends; Education, Professional / trends; Fellowships and Scholarships / trends; Forecasting; Humans; Interinstitutional Relations; Needs Assessment / trends; Professional Competence; Research Support as Topic / trends; Toxicology / education; Toxicology / trends
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 35(2), 113–120.

By: K. Clothier*, T. Leavens n , R. Griffith*, S. Wetzlich*, R. Baynes n, J. Riviere n, L. Tell *

co-author countries: United States of America 🇺🇸
MeSH headings : Adipose Tissue; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Disaccharides / administration & dosage; Disaccharides / blood; Disaccharides / pharmacokinetics; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Residues; Female; Goats / metabolism; Heterocyclic Compounds / administration & dosage; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Infusions, Subcutaneous; Kidney; Liver; Lung; Male; Muscle, Skeletal; Reproducibility of Results; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus)

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 34(5), 448–454.

By: K. Clothier*, T. Leavens n , R. Griffith*, S. Wetzlich*, R. Baynes n, J. Riviere n, L. Tell *

co-author countries: United States of America 🇺🇸
MeSH headings : Aging; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Disaccharides / administration & dosage; Disaccharides / blood; Disaccharides / pharmacokinetics; Drug Administration Schedule; Female; Goats / blood; Half-Life; Heterocyclic Compounds / administration & dosage; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Male
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats

RESEARCH IN VETERINARY SCIENCE, 90(3), 477–479.

By: G. Young n, G. Smith n , T. Leavens n , S. Wetzlich*, R. Baynes n, S. Mason n, J. Riviere n, L. Tell *

co-author countries: United States of America 🇺🇸
author keywords: Tulathromycin; Goats; Pharmacokinetics; Respiratory disease; Antibiotics
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Disaccharides / administration & dosage; Disaccharides / blood; Disaccharides / pharmacokinetics; Goats / blood; Goats / metabolism; Half-Life; Heterocyclic Compounds / administration & dosage; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Injections, Subcutaneous / veterinary; Tandem Mass Spectrometry / veterinary
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Evaluation of perfused porcine skin as a model system to quantitate tissue distribution of fullerene nanoparticles

TOXICOLOGY LETTERS, 197(1), 1–6.

By: T. Leavens n , X. Xia  n, H. Lee n, N. Monteiro-Riviere n , J. Brooks  n & J. Riviere n

co-author countries: United States of America 🇺🇸

Contributors: T. Leavens n , X. Xia  n, H. Lee n, N. Monteiro-Riviere n , J. Brooks  n & J. Riviere n

author keywords: nC(60); Isolated perfused porcine skin flaps; Pharmacokinetics; In vitro; Nanoparticles; Skin
MeSH headings : Animals; Arteries / metabolism; Colloids; Female; Fullerenes / pharmacokinetics; Immunoglobulin G / metabolism; Models, Animal; Nanoparticles / ultrastructure; Skin / metabolism; Swine; Tissue Distribution; Veins / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Pharmacokinetics of radiolabeled tungsten (W-188) in male Sprague-Dawley rats following acute sodium tungstate inhalation

INHALATION TOXICOLOGY, 22(1), 69–76.

By: P. Radcliffe*, T. Leavens n , D. Wagner*, A. Olabisi*, M. Struve n, B. Wong*, E. Tewksbury*, G. Chapman*, D. Dorman n

co-author countries: United States of America 🇺🇸
author keywords: Inhalation; kinetics; tungsten
MeSH headings : Administration, Inhalation; Aerosols; Animals; Inhalation Exposure; Male; Metabolic Clearance Rate; Models, Biological; Radioisotopes; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tungsten Compounds / pharmacokinetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Physiologically based pharmacokinetic rat model for methyl tertiary-butyl ether; comparison of selected dose metrics following various MTBE exposure scenarios used for toxicity and carcinogenicity evaluation

TOXICOLOGY, 275(1-3), 79–91.

By: S. Borghoff, H. Parkinson & T. Leavens* 

author keywords: MTBE; TBA; PBPK
MeSH headings : Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical / methods; Female; Inhalation Exposure / adverse effects; Kidney / drug effects; Kidney / physiology; Male; Methyl Ethers / administration & dosage; Methyl Ethers / pharmacokinetics; Methyl Ethers / toxicity; Models, Animal; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Acute sodium tungstate inhalation is associated with minimal olfactory transport of tungsten (W-188) to the rat brain

NEUROTOXICOLOGY, 30(3), 445–450.

By: P. Radcliffe*, A. Olabisi*, D. Wagner*, T. Leavens n , B. Wong*, M. Struve n, G. Chapman*, E. Wilfong*, D. Dorman n

co-author countries: United States of America 🇺🇸
author keywords: Inhalation; Olfactory transport; Brain; Tungsten; Single-dose; Rat
MeSH headings : Administration, Inhalation; Aerosols; Animals; Corpus Striatum / metabolism; Male; Olfactory Pathways / metabolism; Pituitary Gland / metabolism; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tungsten Compounds / administration & dosage; Tungsten Compounds / blood; Tungsten Compounds / pharmacokinetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Physiologically Based Pharmacokinetic Model of Methyl Tertiary Butyl Ether and Tertiary Butyl Alcohol Dosimetry in Male Rats Based on Binding to alpha 2u-Globulin

TOXICOLOGICAL SCIENCES, 109(2), 321–335.

By: T. Leavens n  & S. Borghoff*

co-author countries: United States of America 🇺🇸
author keywords: MTBE; TBA; alpha 2u-globulin; PBPK
MeSH headings : Algorithms; Alpha-Globulins / metabolism; Animals; Brain Chemistry; Computer Simulation; Dose-Response Relationship, Drug; Female; Inhalation Exposure; Kidney / metabolism; Liver / metabolism; Male; Methyl Ethers / administration & dosage; Methyl Ethers / metabolism; Methyl Ethers / pharmacokinetics; Methyl Ethers / toxicity; Models, Biological; Models, Chemical; Protein Binding; Rats; Rats, Inbred F344; Testis / metabolism; Toxicity Tests, Acute; Toxicity Tests, Chronic; tert-Butyl Alcohol / blood; tert-Butyl Alcohol / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018