Tonya L Harris

Works (17)

Updated: April 5th, 2024 03:04

2022 journal article

The use of autologous skeletal muscle progenitor cells for adjunctive treatment of presumptive urethral sphincter mechanism incompetence in female dogs

Journal of Veterinary Internal Medicine, 36(5), 1686–1692.

By: S. Vaden n , K. Mathews n, J. Yoo *, J. Williams *, T. Harris n, P. Secoura n, J. Robertson n , K. Gleason n, H. Reynolds n, J. Piedrahita n 

Contributors: J. Robertson n 

author keywords: canine; regenerative medicine; stem cell; urinary incontinence
MeSH headings : Animals; Dog Diseases / surgery; Dogs; Female; Muscle, Skeletal; Stem Cells; Urethra / surgery; Urinary Incontinence / therapy; Urinary Incontinence / veterinary
TL;DR: Urethral submucosal injection of autologous skeletal muscle progenitor cells (skMPC) can be used adjunctively to improve continence in dogs with difficult to manage USMI. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 26, 2022

2019 journal article

Antimicrobial Activity of Ceftiofur and Penicillin With Gentamicin Against Escherichia coli and Streptococcus equi Subspecies zooepidemicus in an Ex Vivo Model of Equine Postpartum Uterine Disease

JOURNAL OF EQUINE VETERINARY SCIENCE, 79, 121–126.

By: K. Von Dollen n, M. Jones n, T. Beachler n, T. Harris n, M. Papich n , S. Lyle n, C. Bailey n

author keywords: E. coli; S. zooepidemicus; Postpartum mare; Antibiotic use
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Female; Gentamicins; Horse Diseases / drug therapy; Horses; Humans; Penicillins; Postpartum Period; Streptococcus equi; Uterine Diseases / drug therapy; Uterine Diseases / veterinary
TL;DR: The intrauterine infusion of procaine penicillin G with gentamicin in cases of postpartum uterine disease caused by E. coli or S. zooepidemicus is supported by the results of this work. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 26, 2019

2019 journal article

Outcomes Following Balloon Dilation of Benign Urethral Strictures in Dogs: Eight Cases (2005–2018)

Journal of the American Animal Hospital Association, 56(1), 23–29.

By: T. Gin n, P. Secoura n, T. Harris n & S. Vaden n 

MeSH headings : Animals; Dilatation / methods; Dilatation / veterinary; Dog Diseases / surgery; Dogs; Female; Male; Retrospective Studies; Urethral Stricture / surgery; Urethral Stricture / veterinary
TL;DR: It is suggested that balloon dilation is an effective, minimally invasive procedure for the treatment of benign urethral strictures in dogs. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: February 22, 2021

2017 journal article

Retrospective analysis of the effect of acid-suppressant therapy on clinicopathologic parameters of cats with chronic kidney disease

Journal of Feline Medicine and Surgery, 20(6), 520–527.

By: E. Gould *, J. Klos*, J. Price *, T. Harris n, S. Vaden n  & M. Tolbert *

MeSH headings : Animals; Cat Diseases / chemically induced; Cat Diseases / drug therapy; Cats; Creatinine / blood; Disease Progression; Histamine H2 Antagonists / administration & dosage; Histamine H2 Antagonists / adverse effects; Proton Pump Inhibitors / administration & dosage; Proton Pump Inhibitors / adverse effects; Random Allocation; Renal Insufficiency, Chronic / chemically induced; Renal Insufficiency, Chronic / veterinary; Retrospective Studies
TL;DR: Results of this retrospective study suggest that cats with CKD receiving PPI therapy may develop alterations in blood sodium concentrations but do not experience more rapid progression of CKD. (via Semantic Scholar)
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Sources: NC State University Libraries, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Use of a Granulocyte Immunofluorescence Assay Designed for Humans for Detection of Antineutrophil Cytoplasmic Antibodies in Dogs with Chronic Enteropathies

Journal of Veterinary Internal Medicine, 31(4), 1062–1066.

By: J. Florey *, A. Viall *, S. Streu*, V. DiMuro*, A. Riddle*, J. Kirk *, L. Perazzotti, K. Affeldt* ...

author keywords: Antineutrophil cytoplasmic antibodies; Chronic enteropathy; Food-responsive disease; Indirect immunofluorescence
MeSH headings : Animals; Antibodies, Antineutrophil Cytoplasmic / blood; Antibodies, Antineutrophil Cytoplasmic / immunology; Case-Control Studies; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Female; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Gastrointestinal Diseases / blood; Gastrointestinal Diseases / diagnosis; Gastrointestinal Diseases / immunology; Gastrointestinal Diseases / veterinary; Granulocytes / immunology; Male
TL;DR: A commercially available granulocyte IIF assay designed for humans could be used to detect perinuclear antineutrophil cytoplasmic antibodies in dogs, and agreement with the previously published method was good. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Effect of Cranberry Extract on the Frequency of Bacteriuria in Dogs with Acute Thoracolumbar Disk Herniation: A Randomized Controlled Clinical Trial

Journal of Veterinary Internal Medicine, 31(1), 60–68.

By: N. Olby n , S. Vaden n , K. Williams n, E. Griffith n , T. Harris n, C. Mariani n , K. Muñana n , P. Early n ...

Contributors: N. Olby n , S. Vaden n , K. Williams n, E. Griffith n , T. Harris n, C. Mariani n , K. Muñana n , P. Early n ...

author keywords: Escherichia coli; Incontinence; Proanthocyanidins; Spinal cord injury
MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / therapeutic use; Bacteriuria / complications; Bacteriuria / drug therapy; Bacteriuria / urine; Bacteriuria / veterinary; Dog Diseases / drug therapy; Dogs; Female; Intervertebral Disc Displacement / complications; Intervertebral Disc Displacement / veterinary; Male; Plant Extracts / administration & dosage; Plant Extracts / therapeutic use; Prospective Studies; Single-Blind Method; Thoracic Vertebrae; Treatment Outcome; Urinary Tract Infections / complications; Urinary Tract Infections / drug therapy; Urinary Tract Infections / urine; Urinary Tract Infections / veterinary; Vaccinium macrocarpon
TL;DR: This clinical trial did not show a benefit of oral cranberry extract but had low power, but a possible association between urine AAA and lower risk of E. coli bacteriuria was identified. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Recovery of stepping and coordination in dogs following acute thoracolumbar intervertebral disc herniations

The Veterinary Journal, 213, 59–63.

By: C. Rousse n, N. Olby n , K. Williams n, T. Harris n, E. Griffith n , C. Mariani n , K. Muñana n , P. Early n

Contributors: C. Rousse n, N. Olby n , K. Williams n, T. Harris n, E. Griffith n , C. Mariani n , K. Muñana n , P. Early n

author keywords: Canine; Gait; Locomotion; Paralysis; Spinal cord injury
MeSH headings : Acute Disease; Animals; Dog Diseases / etiology; Dog Diseases / surgery; Dogs; Female; Forelimb / physiology; Hindlimb / physiology; Intervertebral Disc / pathology; Intervertebral Disc / surgery; Intervertebral Disc Displacement / etiology; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Male; Prospective Studies; Spinal Cord Injuries / etiology; Spinal Cord Injuries / surgery; Spinal Cord Injuries / veterinary; Walking
TL;DR: Recovery of coordination was incomplete in dogs that showed good recovery of stepping in the 6 weeks following surgical decompression of dogs with TL-IVDH. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Canine hereditary ataxia in Old English Sheepdogs and Gordon Setters is associated with a defect in the autophagy gene encoding RAB24

PLoS Genetics, 10(2).

By: C. Agler, D. Nielsen , G. Urkasemsin, A. Singleton, N. Tonomura, S. Sigurdsson, R. Tang, K. Linder ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Gait scoring in dogs with thoracolumbar spinal cord injuries when walking on a treadmill

BMC Veterinary Research, 10.

By: N. Olby , J. Lim, K. Babb, K. Bach, C. Domaracki, K. Williams, E. Griffith, T. Harris, A. Muguet-Chanoit

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Vaginal Microbiota of Spayed Dogs with or without Recurrent Urinary Tract Infections

JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(2), 300–304.

By: R. Hutchins*, S. Vaden n , M. Jacob n, T. Harris n, K. Bowles n, M. Wood n, C. Bailey n

author keywords: Recurrent urinary tract infection; Lactic acid-producing bacteria
MeSH headings : Animals; Dog Diseases / microbiology; Dogs / microbiology; Female; Microbiota; Ovariectomy / veterinary; Recurrence; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary; Vagina / microbiology
TL;DR: The vaginal microbiota of spayed female dogs with recurrent UTI was similar to the control population of normal, spayed male dogs and vaginal bacteria isolate from vaginal swabs obtained from each dog. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

The Effect of an Oral Probiotic Containing <i>Lactobacillus</i>,<i> Bifidobacterium,</i> and <i>Bacillus</i> Species on the Vaginal Microbiota of Spayed Female Dogs

Journal of Veterinary Internal Medicine, 27(6), 1368–1371.

By: R. Hutchins n, C. Bailey n, M. Jacob n, T. Harris n, M. Wood n, K. Saker n, S. Vaden n 

author keywords: Lactic acid-producing bacteria; Recurrent urinary tract infection
MeSH headings : Animals; Bacillus / genetics; Bacillus / isolation & purification; Bifidobacterium / genetics; Bifidobacterium / isolation & purification; Dog Diseases / microbiology; Dog Diseases / prevention & control; Dogs; Female; Lactobacillus / genetics; Lactobacillus / isolation & purification; Microbiota / genetics; Probiotics / pharmacology; Sequence Analysis, DNA; Urinary Tract Infections / microbiology; Urinary Tract Infections / prevention & control; Urinary Tract Infections / veterinary; Vagina / microbiology
TL;DR: Administration of this oral probiotic supplement for a 2- or 4-week period did not increase the prevalence of vaginal LAB in dogs and Enterococcus canintestini was the most common LAB isolated from all dogs in this study, although it was not included in the probiotics supplement. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

A case-control study of nephrotic syndrome in dogs: 78 cases

Journal of Veterinary Internal Medicine, 25(2), 206–214.

By: E. Klosterman *, G. Moore *, J. de Brito Galvao *, S. Di Bartola*, R. Groman*, J. Whittemore *, S. Vaden n , T. Harris n ...

author keywords: Amyloidosis; Ascites; Membranoproliferative glomerulonephritis; Membranous glomerulopathy
MeSH headings : Albuminuria / etiology; Albuminuria / veterinary; Animals; Azotemia / etiology; Azotemia / veterinary; Case-Control Studies; Creatinine / blood; Creatinine / metabolism; Dog Diseases / mortality; Dog Diseases / pathology; Dogs; Female; Glomerulonephritis, Membranous; Kidney Diseases / complications; Kidney Diseases / mortality; Kidney Diseases / pathology; Kidney Diseases / veterinary; Kidney Glomerulus / pathology; Male; Nephrotic Syndrome / complications; Nephrotic Syndrome / mortality; Nephrotic Syndrome / pathology; Nephrotic Syndrome / veterinary; Prognosis; Proteinuria / etiology; Proteinuria / veterinary; Retrospective Studies
TL;DR: Presence of Nephrotic syndrome is associated with poorer prognosis in dogs with nonazotemic glomerular disease and Preventing development of NS is warranted; however, specific interventions were not evaluated. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2010 journal article

The prevalence of albuminuria in dogs and cats in an ICU or recovering from anesthesia

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 20(5), 479–487.

By: S. Vaden n , C. Turman n, T. Harris n & S. Marks n

author keywords: microalbuminuria; urine albumin
MeSH headings : Albuminuria / veterinary; Anesthesia / veterinary; Anesthesia Recovery Period; Animals; Cat Diseases / urine; Cats; Dog Diseases / urine; Dogs; Intensive Care Units
TL;DR: The prevalence of albuminuria in animals admitted to the ICU or recovering from anesthesia is higher than reported previously and transient in some patients, and the presence ofalbuminuria may be a negative prognostic indicator in this population of animals. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

The use of pooled vs serial urine samples to measure urine protein:creatinine ratios

VETERINARY CLINICAL PATHOLOGY, 39(1), 53–56.

By: D. LeVine n, D. Zhang n, T. Harris n & S. Vaden n 

author keywords: Dog; proteinuria; protein:creatinine ratio; UPC
MeSH headings : Animals; Creatinine / urine; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Kidney Failure, Chronic / urine; Kidney Failure, Chronic / veterinary; Proteinuria / veterinary; Specimen Handling
TL;DR: Measuring the UPC ratio in a pooled sample containing equal volumes of several different urine specimens from the same dog provides a reliable and cost-effective alternative to assessing multiple UPC ratios on several specimens fromThe same dog. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 article

Evaluation of perinuclear anti-neutrophilic cytoplasmic autoantibodies as an early marker of protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers

Allenspach, K., Lomas, B., Wieland, B., Harris, T., Pressler, B., Mancho, C., … Vaden, S. L. (2008, October). AMERICAN JOURNAL OF VETERINARY RESEARCH, Vol. 69, pp. 1301–1304.

By: K. Allenspach *, B. Lomas, B. Wieland, T. Harris*, B. Pressler*, C. Mancho, G. Lees, S. Vaden* 

MeSH headings : Animals; Antibodies, Antineutrophil Cytoplasmic / blood; Autoantibodies / blood; Dog Diseases / blood; Dog Diseases / immunology; Dogs; Kidney Diseases / etiology; Kidney Diseases / immunology; Kidney Diseases / veterinary; Protein-Losing Enteropathies / complications; Protein-Losing Enteropathies / immunology; Protein-Losing Enteropathies / veterinary; Species Specificity
TL;DR: Most dogs in this study affected with PLE, PLN, or both had positive results for pANCAs before clinicopathologic evidence of disease was detected and may be useful as an early noninvasive test of disease in SCWTs. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2004 journal article

Recovery of pelvic limb function in dogs following acute intervertebral disc herniations

JOURNAL OF NEUROTRAUMA, 21(1), 49–59.

By: N. Olby n , T. Harris n, J. Burr n, K. Munana n , N. Sharp n & B. Keene n

Contributors: N. Olby n , T. Harris n, J. Burr n, K. Muñana n , N. Sharp n & B. Keene n

author keywords: dog; disc herniation; functional recovery; spinal cord compression; spinal cord trauma
MeSH headings : Animals; Disease Models, Animal; Dogs; Hindlimb / physiopathology; Intervertebral Disc Displacement / complications; Intervertebral Disc Displacement / physiopathology; Lumbosacral Region / physiopathology; Pelvis / pathology; Recovery of Function; Spinal Cord Injuries / etiology; Spinal Cord Injuries / physiopathology; Thoracic Vertebrae / physiopathology
TL;DR: It is concluded that dogs with spontaneous disc herniations provide a useful model of acute spinal cord injury for clinical trials and are suitable for use in clinical trials on neuroprotective drugs. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2003 journal article

Long-term functional outcome of dogs with severe injuries of the thoracolumbar spinal cord: 87 cases (1996–2001)

Journal of the American Veterinary Medical Association, 222(6), 762–769.

By: N. Olby n , J. Levine n , T. Harris*, K. Muñana n , T. Skeen n & N. Sharp n

Contributors: N. Olby n , J. Levine n , T. Harris*, K. Muñana n , T. Skeen n & N. Sharp n

MeSH headings : Age Factors; Animals; Body Weight; Dog Diseases / physiopathology; Dog Diseases / surgery; Dogs; Female; Intervertebral Disc Displacement / physiopathology; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Laminectomy / veterinary; Lumbar Vertebrae; Male; Pain / veterinary; Paraplegia / etiology; Paraplegia / surgery; Paraplegia / veterinary; Prognosis; Recovery of Function; Retrospective Studies; Spinal Cord Injuries / physiopathology; Spinal Cord Injuries / surgery; Spinal Cord Injuries / veterinary; Thoracic Vertebrae; Treatment Outcome
TL;DR: Results suggested that the prognosis for paraplegic dogs without DPP because of trauma was guarded, while dogs with disk herniation had a better chance of recovering motor function. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

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