Works (3)

Updated: January 16th, 2024 08:10

2020 article

Platelet aggregometry testing during aspirin or clopidogrel treatment and measurement of clopidogrel metabolite concentrations in dogs with protein-losing nephropathy

JOURNAL OF VETERINARY INTERNAL MEDICINE.

By: S. Shropshire*, T. Johnson n & C. Olver*

MeSH headings : Animals; Aspirin / therapeutic use; Case-Control Studies; Clopidogrel / metabolism; Clopidogrel / therapeutic use; Dog Diseases / drug therapy; Dogs; Female; Male; Platelet Aggregation; Platelet Aggregation Inhibitors / metabolism; Platelet Aggregation Inhibitors / therapeutic use; Protein-Losing Enteropathies / blood; Protein-Losing Enteropathies / pathology; Protein-Losing Enteropathies / veterinary
TL;DR: Platelet aggregometry may represent an objective method to evaluate response to clopidogrel or aspirin treatment and PLN dogs appear to metabolize clopIDogrel similarly to healthy dogs. (via Semantic Scholar)
Source: Web Of Science
Added: February 10, 2020

2019 journal article

Carbon monoxide releasing molecule enhances coagulation and decreases fibrinolysis in canine plasma exposed to Crotalus viridis venom in vitro and in vivo

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 125(4), 328–336.

By: T. Johnson n, R. Wells, A. Bell*, V. Nielsen* & C. Olver*

author keywords: Carbon monoxide releasing molecules; coagulation; coagulopathy; dog; venom
MeSH headings : Animals; Blood Coagulation Disorders / chemically induced; Blood Coagulation Disorders / drug therapy; Blood Coagulation Disorders / veterinary; Crotalid Venoms / toxicity; Crotalus; Dogs; Fibrinolysis / drug effects; Organometallic Compounds / administration & dosage; Snake Bites / blood; Snake Bites / drug therapy; Snake Bites / veterinary; Thrombelastography; Treatment Outcome
TL;DR: It is shown that CORM‐2 has similar effects in vitro on plasma from naturally envenomed dogs, showing promise as an adjunct therapy for snake envenomation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 7, 2019

2018 journal article

Secretion and fusion of biogeochemically active archaeal membrane vesicles

GEOBIOLOGY, 16(6), 659–673.

By: T. Johnson*, C. Mach*, R. Grove*, R. Kelly n, K. Van Cott* & P. Blum*

author keywords: archaea; membrane fusion; regulated secretion; thermoacidophiles; vesicles
MeSH headings : Archaea / metabolism; Archaea / physiology; Archaeal Proteins / metabolism
TL;DR: Membrane vesicles may play a role in modulating energy‐related traits in geochemical environments by fusion‐mediated protein delivery as well as in response to unknown signals and for undefined purposes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: October 29, 2018

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