Works (188)

Updated: April 11th, 2023 10:13

2021 journal article

A double-blind, 377-subject randomized study identifies Ruminococcus, Coprococcus, Christensenella, and Collinsella as long-term potential key players in the modulation of the gut microbiome of lactose intolerant individuals by galacto-oligosaccharides

GUT MICROBES, 13(1).

By: M. Azcarate-Peril*, J. Roach*, A. Marsh*, W. Chey*, W. Sandborn*, A. Ritter*, D. Savaiano*, T. Klaenhammer

author keywords: Prebiotics; microbiome modulation; lactose intolerance; human lactase; Bifidobacterium; short chain fatty acids; galacto-oligosaccharides; GOS
Source: Web Of Science
Added: August 16, 2021

2021 journal article

In Vivo Transcriptome of Lactobacillus acidophilus and Colonization Impact on Murine Host Intestinal Gene Expression

MBIO, 12(1).

By: Y. Goh, R. Barrangou & T. Klaenhammer

Ed(s): G. Huffnagle

author keywords: Lactobacillus; acidophilus; gut adaptation; in vivo gene expression; mouse colonization; probiotic
Sources: Web Of Science, ORCID
Added: January 26, 2021

2019 article

Get Cultured: Eat Bacteria

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 10, Vol. 10, pp. 1–20.

By: T. Klaenhammer

author keywords: Klaenhammer; food science; microbiology; genomics; biotechnology; lactic acid bacteria; probiotics; prebiotics
Source: Web Of Science
Added: April 22, 2019

2018 journal article

Deletion-based escape of CRISPR-Cas9 targeting in Lactobacillus gasseri

MICROBIOLOGY-SGM, 164(9), 1098–1111.

By: E. Stout n, R. Sanozky-Dawes, Y. Goh, A. Crawley, T. Klaenhammer & R. Barrangou

author keywords: Lactobacillus; CRISPR; Cas; Cas9; interference; spacer
Sources: Web Of Science, ORCID
Added: December 31, 2018

2018 journal article

Nod2 is required for antigen-specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform

PLOS ONE, 13(5).

By: S. Bumgardner n, L. Zhang*, A. LaVoy*, B. Andre, C. Frank*, A. Kajikawa*, T. Klaenhammer, G. Dean*

Source: Web Of Science
Added: August 6, 2018

2018 journal article

Phenotypic and genotypic diversity of Lactobacillus buchneri strains isolated from spoiled, fermented cucumber

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 280, 46–56.

By: K. Daughtry n, S. Johanningsmeier, R. Sanozky-Dawes, T. Klaenhammer & R. Barrangou

author keywords: Lactic acid bacteria; Pickled vegetables; Spoilage organisms; Lactobacillus buchneri; Strain diversity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

An Extracellular Cell-Attached Pullulanase Confers Branched alpha-Glucan Utilization in Human Gut Lactobacillus acidophilus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 83(12).

By: M. Moller*, Y. Goh, K. Rasmussen*, W. Cypryk*, H. Celebioglu*, T. Klaenhammer, B. Svensson*, M. Abou Hachem*

author keywords: glycoside hydrolase family 13; human gut microbiota; starch; starch binding modules
Source: Web Of Science
Added: August 6, 2018

2017 article

CRISPR-Cas Technologies and Applications in Food Bacteria

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 8, Vol. 8, pp. 413–437.

By: E. Stout n, T. Klaenhammer & R. Barrangou

author keywords: probiotics; cultures; strain-typing; phage resistance; plasmid vaccination; antimicrobial; genome editing
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Deletion of Lipoteichoic Acid Synthase Impacts Expression of Genes Encoding Cell Surface Proteins in Lactobacillus acidophilus

Frontiers in Microbiology, 8.

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals

MBIO, 8(6).

By: M. Theilmann*, Y. Goh, K. Nielsen*, T. Klaenhammer, R. Barrangou & M. Abou Hachem*

Ed(s): E. Martens & M. McFall-Ngai

author keywords: Lactobacillus; beta-glucoside; bioavailability; gut microbiota; phytochemical; polydatin; polyphenols; resveratrol; xenobiotic metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

The S-layer Associated Serine Protease Homolog PrtX Impacts Cell Surface-Mediated Microbe-Host Interactions of Lactobacillus acidophilus NCFM

FRONTIERS IN MICROBIOLOGY, 8.

By: B. Johnson, S. O'Flaherty, Y. Goh, I. Carroll, R. Barrangou & T. Klaenhammer

author keywords: serine protease; S-layer; S-layer associated proteins; Lactobacillus; probiotic; intestinal barrier integrity; mucin; fibronectin
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

AcmB Is an S-Layer-Associated beta-N-Acetylglucosaminidase and Functional Autolysin in Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(18), 5687–5697.

By: B. Johnson & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2016 journal article

Conserved S-Layer-Associated Proteins Revealed by Exoproteomic Survey of S-Layer-Forming Lactobacilli

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(1), 134–145.

Ed(s): H. Nojiri

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Development of a Transportation System Simulation Manual Framework From Theory to Practice

TRANSPORTATION RESEARCH RECORD, (2561), 45–52.

By: G. List, M. Mashayekhi, R. Bertini* & B. Nevers*

Source: Web Of Science
Added: August 6, 2018

2016 journal article

Differential proteome and cellular adhesion analyses of the probiotic bacterium Lactobacillus acidophilus NCFM grown on raffinose - an emerging prebiotic

PROTEOMICS, 16(9), 1361–1375.

By: H. Celebioglu*, M. Ejby*, A. Majumder*, C. Kobler*, Y. Goh, K. Thorsen*, B. Schmidt*, S. O'Flaherty ...

author keywords: Adhesion; HT-29 cells; Moonlighting proteins; Probiotics; Raffinose; Surface and whole cell proteomes
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Functional Analysis of an S-Layer-Associated Fibronectin-Binding Protein in Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(9), 2676–2685.

By: J. Hymes, B. Johnson, R. Barrangou & T. Klaenhammer

Ed(s): E. Dudley

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Genomic evolution of lactic acid bacteria: From single gene function to the pan-genome

Biotechnology of Lactic Acid Bacteria: Novel Applications, 2nd Edition, 32–54.

By: G. Douglas*, M. Azcarate-Peril* & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Intracellular and Extracellular Expression of Bacillus thuringiensis Crystal Protein Cry5B in Lactococcus lactis for Use as an Anthelminthic

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(4), 1286–1294.

By: E. Durmaz, Y. Hu*, R. Aroian* & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2016 journal article

Multivalent Chromosomal Expression of the Clostridium botulinum Serotype A Neurotoxin Heavy-Chain Antigen and the Bacillus anthracis Protective Antigen in Lactobacillus acidophilus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(20), 6091–6101.

By: S. O'Flaherty & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2016 review

Stuck in the Middle: Fibronectin-Binding Proteins in Gram-Positive Bacteria

[Review of ]. FRONTIERS IN MICROBIOLOGY, 7.

By: J. Hymes & T. Klaenhammer

author keywords: fibronectin; Lactobacillus; Acidophifus; lactobacilli; streptococci
Source: Web Of Science
Added: August 6, 2018

2015 journal article

CRISPR-based screening of genomic island excision events in bacteria

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(26), 8076–8081.

By: K. Selle, T. Klaenhammer & R. Barrangou

author keywords: CRISPR; lactic acid bacteria; transposons; IS-elements; Cas9
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera

NATURE COMMUNICATIONS, 6.

By: Z. Sun*, H. Harris*, A. McCann*, C. Guo*, S. Argimon*, W. Zhang*, X. Yang*, I. Jeffery* ...

Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 article

Genetic Mechanisms of Prebiotic Oligosaccharide Metabolism in Probiotic Microbes

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 6, Vol. 6, pp. 137–156.

By: Y. Goh & T. Klaenhammer

author keywords: Lactobacillus; Bifidobacterium; fructooligosaccharide; galactooligosaccharide; prebiotic; probiotic
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Mucosal Immunogenicity of Genetically Modified Lactobacillus acidophilus Expressing an HIV-1 Epitope within the Surface Layer Protein

PLOS ONE, 10(10).

By: A. Kajikawa*, L. Zhang*, A. LaVoy*, S. Bumgardner, T. Klaenhammer & G. Dean*

Source: Web Of Science
Added: August 6, 2018

2015 journal article

Occurrence and activity of a type II CRISPR-Cas system in Lactobacillus gasseri

MICROBIOLOGY-SGM, 161, 1752–1761.

Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

SIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis

EMBO JOURNAL, 34(7), 881–895.

By: Y. Lightfoot*, K. Selle, T. Yang*, Y. Goh, B. Sahay*, M. Zadeh*, J. Owen*, N. Colliou* ...

author keywords: colitis; immune regulation; Lactobacillus acidophilus; SIGNR3; surface layer protein A
Source: Web Of Science
Added: August 6, 2018

2015 article

Sortase-deficient lactobacilli: effect on immunomodulation and gut retention

Call, E. K., Goh, Y. J., Selle, K., Klaenhammer, T. R., & O'Flaherty, S. (2015, February). MICROBIOLOGY-SGM, Vol. 161, pp. 311–321.

By: E. Call n, Y. Goh, K. Selle, T. Klaenhammer & S. O'Flaherty

Source: Web Of Science
Added: August 6, 2018

2014 article

Effects of genetic, processing, or product formulation changes on efficacy and safety of probiotics

ANNALS REPORTS, Vol. 1309, pp. 1–18.

By: M. Sanders*, T. Klaenhammer, A. Ouwehand*, B. Pot*, E. Johansen*, J. Heimbach*, M. Marco*, J. Tennila* ...

author keywords: probiotic; genetics; gene expression; regulatory; safety; efficacy
Source: Web Of Science
Added: August 6, 2018

2014 review

Impact of genomics on the field of probiotic research: historical perspectives to modern paradigms

[Review of ]. ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 106(1), 141–156.

By: B. Johnson & T. Klaenhammer

author keywords: Probiotic; Lactic acid bacteria; Fermentation; Genomics; Lactobacilli; Bifidobacteria
Source: Web Of Science
Added: August 6, 2018

2014 review

Insights into glycogen metabolism in Lactobacillus acidophilus: impact on carbohydrate metabolism, stress tolerance and gut retention

[Review of ]. MICROBIAL CELL FACTORIES, 13.

By: Y. Goh & T. Klaenhammer

author keywords: Lactobacilli; Glycogen; Probiotic; Raffinose; Gastrointestinal retention
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Microbiology bacteria get vaccinated

Nature, 513(7517), 175–176.

By: R. Barrangou & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Recent insight in alpha-glucan metabolism in probiotic bacteria

BIOLOGIA, 69(6), 713–721.

By: M. Moller*, Y. Goh, A. Viborg*, J. Andersen*, T. Klaenhammer, B. Svensson*, M. Abou Hachem*

author keywords: prebiotic; oligosaccharide uptake; ATP-binding cassette transport system; phosphotransferase system; transcriptional analysis; isomalto-oligosaccharide; malto-oligosaccharide
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Spontaneously Induced Prophages in Lactobacillus gasseri Contribute to Horizontal Gene Transfer

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(11), 3508–3517.

By: J. Baugher, E. Durmaz & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2013 journal article

A functional glycogen biosynthesis pathway in Lactobacillus acidophilus: expression and analysis of the glg operon

MOLECULAR MICROBIOLOGY, 89(6), 1187–1200.

By: Y. Goh & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2013 review

Genomic and phenotypic evidence for probiotic influences of Lactobacillus gasseri on human health

[Review of ]. FEMS MICROBIOLOGY REVIEWS, 37(6), 915–935.

By: K. Selle & T. Klaenhammer

author keywords: gastrointestinal tract; acidophilus complex; bacteriocin; lactic acid bacteria; autochthonous; microbiota
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Identification of extracellular surface-layer associated proteins in Lactobacillus acidophilus NCFM

MICROBIOLOGY-SGM, 159, 2269–2282.

By: B. Johnson, K. Selle, S. O'Flaherty, Y. Goh & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2013 journal article

Improving lactose digestion and symptoms of lactose intolerance with a novel galacto-oligosaccharide (RP-G28): a randomized, double-blind clinical trial

NUTRITION JOURNAL, 12.

By: D. Savaiano*, A. Ritter*, T. Klaenhammer, G. James*, A. Longcore*, J. Chandler*, W. Walker*, H. Foyt*

author keywords: Lactose intolerance; Colonic adaptation; Galacto-oligosaccharides; GOS; Hydrogen breath test; RP-G28; Microbiome; Microflora
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Probiotics, prebiotics, and the host microbiome: the science of translation

ANNALS REPORTS, 1306, 1–17.

By: B. Petschow*, J. Dore*, P. Hibberd*, T. Dinan*, G. Reid*, M. Blaser*, P. Cani*, F. Degnan* ...

author keywords: microbiome; probiotics; prebiotics; intestinal microbiota; health disorders
Source: Web Of Science
Added: August 6, 2018

2013 review

Recent insight into oligosaccharide uptake and metabolism in probiotic bacteria

[Review of ]. BIOCATALYSIS AND BIOTRANSFORMATION, 31(4), 226–235.

By: M. Abou Hachem*, J. Andersen*, R. Barrangou, M. Moller*, F. Fredslund*, A. Majumder*, M. Ejby*, S. Lahtinen* ...

author keywords: Prebiotic; oligosaccharide uptake; ATP-binding cassette transport system; phosphotransferase system; transcriptional analysis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 review

Relevance and application of sortase and sortase-dependent proteins in lactic acid bacteria

[Review of ]. FRONTIERS IN MICROBIOLOGY, 4.

By: E. Call & T. Klaenhammer

author keywords: probiotic; sortase; sortase-dependent protein; LPXTG; lactic acid bacteria; lactobacillus; lactococcus
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Transcriptional analysis of oligosaccharide utilization by Bifidobacterium lactis Bl-04

BMC GENOMICS, 14(1).

By: J. Andersen n, R. Barrangou, M. Abou Hachem*, S. Lahtinen*, Y. Goh, B. Svensson*, T. Klaenhammer

author keywords: Bifidobacterium lactis; Transcriptomics; ABC transporter; GPH transporter; Prebiotics; Glycoside hydrolase
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(26), 10462–10467.

By: K. Khazaie*, M. Zadeh*, M. Khan*, P. Bere*, F. Gounari*, K. Dennis*, N. Blatner*, J. Owen*, T. Klaenhammer, M. Mohamadzadeh

author keywords: dendritic cells; regulatory T cells; anti-inflammatory
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Characterization of the fecal microbiota using high-throughput sequencing reveals a stable microbial community during storage

PLoS One, 7(10).

By: I. Carroll*, T. Ringel-Kulka*, J. Siddle*, T. Klaenhammer & Y. Ringel*

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Construction and Immunological Evaluation of Dual Cell Surface Display of HIV-1 Gag and Salmonella enterica Serovar Typhimurium FliC in Lactobacillus acidophilus for Vaccine Delivery

CLINICAL AND VACCINE IMMUNOLOGY, 19(9), 1374–1381.

By: A. Kajikawa*, L. Zhang*, J. Long, S. Nordone n, L. Stoeker, A. LaVoy*, S. Bumgardner, T. Klaenhammer, G. Dean

Source: Web Of Science
Added: August 6, 2018

2012 journal article

Influence of Exposure Time on Gene Expression by Human Intestinal Epithelial Cells Exposed to Lactobacillus acidophilus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(14), 5028–5032.

By: S. O'Flaherty & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2012 journal article

Raffinose family oligosaccharide utilisation by probiotic bacteria: insight into substrate recognition, molecular architecture and diversity of GH36 alpha-galactosidases

BIOCATALYSIS AND BIOTRANSFORMATION, 30(3), 316–325.

By: M. Abou Hachem*, F. Fredslund*, J. Andersen*, R. Larsen*, A. Majumder*, M. Ejby*, G. Van Zanten*, S. Lahtinen* ...

author keywords: prebiotic; probiotic; tetrameric alpha-galactosidases; raffinose; clan GH-D
Source: Web Of Science
Added: August 6, 2018

2012 journal article

The impact of probiotics and prebiotics on the immune system

NATURE REVIEWS IMMUNOLOGY, 12(10), 728–734.

By: T. Klaenhammer, M. Kleerebezem*, M. Kopp & M. Rescigno

Source: Web Of Science
Added: August 6, 2018

2012 journal article

Transcriptional Analysis of Prebiotic Uptake and Catabolism by Lactobacillus acidophilus NCFM

PLOS ONE, 7(9).

By: J. Andersen*, R. Barrangou, M. Abou Hachem*, S. Lahtinen*, Y. Goh, B. Svensson*, T. Klaenhammer

Ed(s): C. Gibas

Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 article

A rendezvous with our microbes

Gordon, J. I., & Klaenhammer, T. R. (2011, March 15). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 108, pp. 4513–4515.

By: J. Gordon* & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2011 journal article

Assessment of Lactobacillus gasseri as a Candidate Oral Vaccine Vector

CLINICAL AND VACCINE IMMUNOLOGY, 18(11), 1834–1844.

By: L. Stoeker, S. Nordone n, S. Gunderson, L. Zhang n, A. Kajikawa, A. LaVoy, M. Miller, T. Klaenhammer, G. Dean

Source: Web Of Science
Added: August 6, 2018

2011 journal article

Directed Chromosomal Integration and Expression of the Reporter Gene gusA3 in Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 77(20), 7365–7371.

By: G. Douglas & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2011 journal article

Dissimilar Properties of Two Recombinant Lactobacillus acidophilus Strains Displaying Salmonella FliC with Different Anchoring Motifs

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 77(18), 6587–6596.

By: A. Kajikawa, S. Nordone*, L. Zhang, L. Stoeker, A. LaVoy, T. Klaenhammer, G. Dean

Source: Web Of Science
Added: August 6, 2018

2011 journal article

Group-specific comparison of four lactobacilli isolated from human sources using differential blast analysis

GENES AND NUTRITION, 6(3), 319–340.

By: E. Altermann & T. Klaenhammer

author keywords: In silico analysis; PAU; Adhesion; Stress response; Bacteriophage
Source: Web Of Science
Added: August 6, 2018

2011 review

Invited review: Application of omics tools to understanding probiotic functionality

[Review of ]. JOURNAL OF DAIRY SCIENCE, 94(10), 4753–4765.

By: J. Baugher & T. Klaenhammer

author keywords: probiotics; omics; function; mechanism
Source: Web Of Science
Added: August 6, 2018

2011 personal communication

Probiotic and prebiotic claims in Europe: seeking a clear roadmap

Guarner, F., Sanders, M. E., Gibson, G., Klaenhammer, T., Cabana, M., Scott, K., … Hill, C. (2011, December).

By: F. Guarner, M. Sanders*, G. Gibson*, T. Klaenhammer, M. Cabana*, K. Scott*, G. Reid*, N. Delzenne*, G. Fahey*, C. Hill*

Source: Web Of Science
Added: August 6, 2018

2011 journal article

Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108, 4623–4630.

By: M. Mohamadzadeh*, E. Pfeiler, J. Brown*, M. Zadeh, M. Gramarossa*, E. Managlia*, P. Bere*, B. Sarraj* ...

author keywords: antiinflammatory; lactobacilli; Toll-like receptor 2; innate immunity
Source: Web Of Science
Added: August 6, 2018

2011 article

The Impact of Omic Technologies on the Study of Food Microbes

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 2, Vol. 2, pp. 353–371.

By: S. O'Flaherty & T. Klaenhammer

author keywords: sequencing; genome; probiotic; pathogen; microbiome; transcriptome
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Transcriptional and functional analysis of galactooligosaccharide uptake by lacS in Lactobacillus acidophilus

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(43), 17785–17790.

By: J. Andersen n, R. Barrangou, M. Abou Hachem*, S. Lahtinen*, Y. Goh, B. Svensson*, T. Klaenhammer

author keywords: lactose permease; catabolite repression element
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Construction of vectors for inducible and constitutive gene expression in Lactobacillus

Microbial Biotechnology, 4(3), 357–367.

By: T. Duong, M. Miller n, R. Barrangou, M. Azcarate-Peril n & T. Klaenhammer

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Functional Roles of Aggregation-Promoting-Like Factor in Stress Tolerance and Adherence of Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(15), 5005–5012.

By: Y. Goh & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2010 journal article

Functional and phenotypic characterization of a protein from Lactobacillus acidophilus involved in cell morphology, stress tolerance and adherence to intestinal cells

MICROBIOLOGY-SGM, 156, 3360–3367.

By: . Sarah J. O'Flaherty & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2010 article

Genomic Evolution of Domesticated Microorganisms

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 1, Vol. 1, pp. 397–414.

By: G. Douglas & T. Klaenhammer

author keywords: lactic acid bacteria; fermentation; food; adaptation; mutation
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Plasmid Transduction Using Bacteriophage Phi adh for Expression of CC Chemokines by Lactobacillus gasseri ADH

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(12), 3878–3885.

By: L. Damelin*, D. Mavri-Damelin*, T. Klaenhammer & C. Tiemessen*

Source: Web Of Science
Added: August 6, 2018

2010 journal article

Targeted expression of anthrax protective antigen by Lactobacillus gasseri as an anthrax vaccine

FUTURE MICROBIOLOGY, 5(8), 1289–1296.

By: M. Mohamadzadeh*, E. Durmaz, M. Zadeh, K. Pakanati*, M. Gramarossa*, V. Cohran*, T. Klaenhammer

author keywords: anthrax vaccine; dendritic cell; high copy expression; Lactobacillus gasseri; oral vaccine delivery; probiotic
Source: Web Of Science
Added: August 6, 2018

2010 article

The role and potential of probiotic bacteria in the gut, and the communication between gut microflora and gut/host

O'Flaherty, S., & Klaenhammer, T. R. (2010, April). INTERNATIONAL DAIRY JOURNAL, Vol. 20, pp. 262–268.

By: S. O'Flaherty & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2009 patent

Compositions comprising promoter sequences and methods of use

By: R. Barrangou, A. Azcarate-Peril, E. Altermann, T. Duong & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Dendritic cell targeting of Bacillus anthracis protective antigen expressed by Lactobacillus acidophilus protects mice from lethal challenge

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(11), 4331–4336.

By: M. Mohamadzadeh*, T. Duong, S. Sandwick*, T. Hoover* & T. Klaenhammer

author keywords: anthrax; lactic acid bacteria; mucosal immunity; oral; vaccine
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Development and Application of a upp-Based Counterselective Gene Replacement System for the Study of the S-Layer Protein SlpX of Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 75(10), 3093–3105.

By: Y. Goh, M. Azcarate-Peril, S. O'Flaherty, E. Durmaz, F. Valence*, J. Jardin*, S. Lortal*, T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2009 review

Genome-scale analyses of health-promoting bacteria: probiogenomics

[Review of ]. NATURE REVIEWS MICROBIOLOGY, 7(1), 61–U77.

By: M. Ventura*, S. O'Flaherty, M. Claesson*, F. Turroni*, T. Klaenhammer, D. Sinderen*, . Paul W. O'Toole*

Source: Web Of Science
Added: August 6, 2018

2009 review

Genomic features of Lactobacillus species

[Review of ]. Frontiers in Bioscience, 14, 1362–1386.

By: Y. Goh & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2009 review

Genomics of lactic acid bacteria

[Review of ]. FEMS MICROBIOLOGY LETTERS, 292(1), 1–6.

By: J. Schroeter & T. Klaenhammer

author keywords: lactic acid bacteria; genomics; fermentation; probiotics
Source: Web Of Science
Added: August 6, 2018

2009 article

Immunogenicity of Lactobacillus gasseri-FliC as an oral mucosal vaccine adjuvant for HIV

RETROVIROLOGY, Vol. 6.

By: S. Gunderson n, S. Nordone n, A. LaVoy, L. Zhang, T. Klaenhammer & G. Dean

Source: Web Of Science
Added: August 6, 2018

2009 patent

Lactobacillus acidophillus nucleic acid sequences encoding cell surface protein homologues and uses therefore

By: T. Klaenhammer, W. Russell, E. Altermann & B. Buck

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor

By: T. Klaenhammer, E. Altermann, M. Azcarate-Peril, O. McAuliffe & W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor

By: T. Klaenhammer, W. Russell, E. Altermann & A. Azcarate-Peril

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy

JOURNAL OF MEDICAL MICROBIOLOGY, 58(5), 663–670.

By: A. Engelbrektson*, J. Korzenik*, A. Pittler*, M. Sanders*, T. Klaenhammer, G. Leyer*, C. Kitts*

Source: Web Of Science
Added: August 6, 2018

2009 journal article

Role of Transporter Proteins in Bile Tolerance of Lactobacillus acidophilus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 75(18), 6013–6016.

By: E. Pfeiler & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2009 journal article

Role of autoinducer-2 on the adhesion ability of Lactobacillus acidophilus

JOURNAL OF APPLIED MICROBIOLOGY, 107(1), 269–279.

By: B. Buck, M. Azcarate-Peril & T. Klaenhammer

author keywords: autoinducer-2; Caco-2; microarray; probiotic
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Temporal gene expression and probiotic attributes of Lactobacillus acidophilus during growth in milk

JOURNAL OF DAIRY SCIENCE, 92(3), 870–886.

By: M. Azcarate-Peril, R. Tallon & T. Klaenhammer

author keywords: Lactobacillus acidophilus; probiotic; microarray analysis; dairy
Source: Web Of Science
Added: August 6, 2018

2009 article

Toll-like receptor activation profiles of wild-type, recombinant, and mutant Lactobacillus: implications for vaccine design

RETROVIROLOGY, Vol. 6.

By: L. Stoeker, S. Nordone, A. LaVoy, R. Tallon n, T. Klaenhammer & G. Dean

Source: Web Of Science
Added: August 6, 2018

2008 article

Analysis of the genome sequence of Lactobacillus gasseri ATCC 33323 reveals the molecular basis of an autochthonous intestinal organism

Azcarate-Peril, M. A., Altermann, E., Goh, Y. J., Tallon, R., Sanozky-Dawes, R. B., Pfeiler, E. A., … Klaenhammer, T. R. (2008, August). APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 74, pp. 4610–4625.

By: M. Azcarate-Peril n, E. Altermann, Y. Goh, R. Tallon n, R. Sanozky-Dawes n, E. Pfeiler, S. O'Flaherty, B. Buck n ...

Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 article

Functional genomics of probiotic Lactobacilli

Klaenhammer, T. R., Altermann, E., Pfeiler, E., Buck, B. L., Goh, Y.-J., O'Flaherty, S., … Duong, T. (2008, September). JOURNAL OF CLINICAL GASTROENTEROLOGY, Vol. 42, pp. S160–S162.

author keywords: Lactobacillus acidophilus; Lactobacillus johnsonii; Lactobacillus plantarum; Lactobacillus gasseri; genomics; probiotic cultures; lactic acid bacteria
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 article

Genome sequence and characteristics of Lrm1, a prophage from industrial Lactobacillus rhamnosus strain M1

Durmaz, E., Miller, M. J., Azcarate-Peril, M. A., Toon, S. P., & Klaenhammer, T. R. (2008, August). APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 74, pp. 4601–4609.

By: E. Durmaz, M. Miller*, M. Azcarate-Peril*, S. Toon* & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor

By: T. Klaenhammer, E. Altermann, R. Barrangou, W. Russell & T. Duong

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer, E. Altermann, B. Buck & W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore

By: T. Klaenhammer, E. Altermann & W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acids and uses thereof

By: T. Klaenhammer, A. Azcarate-Peril & E. Altermann

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(49), 19474–19479.

By: S. Konstantinov*, H. Smidt*, W. Vos*, S. Bruijns*, S. Singh*, F. Valence*, D. Molle*, S. Lortal* ...

author keywords: lactobacilli; DC-SIGN
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Specific Lactobacillus species differentially activate Toll-like receptors and downstream signals in dendritic cells

EXPERT REVIEW OF VACCINES, 7(8), 1155–1164.

By: M. Mohamadzadeh* & T. Klaenhammer

author keywords: adjuvant; dendritic cell; Lactobacillus; MAP kinase; Toll-like receptor
Source: Web Of Science
Added: August 6, 2018

2008 review

Targeting mucosal dendritic cells with microbial antigens from probiotic lactic acid bacteria

[Review of ]. EXPERT REVIEW OF VACCINES, 7(2), 163–174.

By: M. Mohamadzadeh, T. Duong, T. Hoover & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2007 patent

AbiZ phage resistance gene

Washington, DC: U.S. Patent and Trademark Office.

By: E. Durmaz & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Abortive phage resistance mechanism AbiZ speeds the lysis clock to cause premature lysis of phage-infected Lactococcus lactis

JOURNAL OF BACTERIOLOGY, 189(4), 1417–1425.

By: E. Durmaz & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2007 journal article

Anti-inflammatory properties of Lactobacillus gasseri expressing manganese superoxide dismutase using the interleukin 10-deficient mouse model of colitis

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 293(4), G729–G738.

By: I. Carroll*, J. Andrus, J. Bruno-Barcena, T. Klaenhammer, H. Hassan & D. Threadgill*

author keywords: probiotic; Lactobacilli; oxidative stress; inflammatory bowel disease
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Characterization of a novel bile-inducible operon encoding a two-component regulatory system in Lactobacillus acidophilus

JOURNAL OF BACTERIOLOGY, 189(13), 4624–4634.

By: E. Pfeiler, M. Azcarate-Peril & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2007 journal article

Identification of an operon and inducing peptide involved in the production of lactacin B by Lactobacillus acidophilus

JOURNAL OF APPLIED MICROBIOLOGY, 103(5), 1766–1778.

By: A. Dobson n, R. Sanozky-Dawes n & T. Klaenhammer

author keywords: bacteriocin; class II; inducing peptide; Lactobacillus; two-component regulatory system
Source: Web Of Science
Added: August 6, 2018

2007 article

Influence of the dairy environment on gene expression and substrate(1-3)

Klaenhammer, T. R., Azcarate-Peril, M. A., Altermann, E., & Barrangou, R. (2007, March). JOURNAL OF NUTRITION, Vol. 137, pp. 748S–750S.

By: T. Klaenhammer, M. Azcarate-Peril, E. Altermann & R. Barrangou

Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Inhibition of bacteriophage replication in Streptococcus thermophilus by subunit poisoning of primase

MICROBIOLOGY-SGM, 153, 3295–3302.

By: J. Sturino & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2007 journal article

Modification of Lactobacillus beta-glucuronidase activity by random mutagenesis

GENE, 389(2), 122–127.

By: M. Callanan, W. Russell & T. Klaenhammer

author keywords: Lactobacillus gasseri gusA; gene; reporter enzyme; pH range; Epicurian coli
Source: Web Of Science
Added: August 6, 2018

2007 review

The genomics of lactic acid bacteria

[Review of ]. TRENDS IN MICROBIOLOGY, 15(12), 546–553.

By: E. Pfeiler & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2006 journal article

Analysis of treatment effects on the microbial ecology of the human intestine

FEMS MICROBIOLOGY ECOLOGY, 57(2), 239–250.

By: A. Engelbrektson*, J. Korzenik*, M. Sanders*, B. Clement*, G. Leyer*, T. Klaenhammer, C. Kitts*

author keywords: terminal restriction fragment length polymorphism; probiotics; antibiotics; prebiotics; gastrointestinal microbiota
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Characterization of the tre locus and analysis of trehalose cryoprotection in Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(2), 1218–1225.

By: T. Duong, R. Barrangou, W. Russell* & T. Klaenhammer

Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Comparative genomics and transcriptional analysis of prophages identified in the Genomes of Lactobacillus gasseri, Lactobacillus salivarius, and Lactobacillus casei

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(5), 3130–3146.

By: M. Ventura*, C. Canchaya*, V. Bernini*, E. Altermann, R. Barrangou, S. McGrath*, M. Claesson*, Y. Li* ...

Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Comparative genomics of the lactic acid bacteria

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(42), 15611–15616.

By: K. Makarova*, A. Slesarev, Y. Wolf*, A. Sorokin*, B. Mirkin*, E. Koonin, A. Pavlov, N. Pavlova ...

author keywords: evolutionary genomics; fermentation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 review

Engineered bacteriophage-defence systems in bioprocessing

[Review of ]. NATURE REVIEWS MICROBIOLOGY, 4(5), 395–404.

By: J. Sturino & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2006 journal article

Global analysis of carbohydrate utilization by Lactobacillus acidophilus using cDNA microarrays

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(10), 3816–3821.

By: R. Barrangou, M. Azcarate-Peril, T. Duong*, S. Conners, R. Kelly & T. Klaenhammer

author keywords: ATP-binding cassette; carbon catabolite repression; fructooligosaccharide; galactoside-pentose hexuronide
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Transcriptional and functional analysis of oxalyl-coenzyme A (CoA) decarboxylase and formyl-CoA transferase genes from Lactobacillus acidophilus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(3), 1891–1899.

By: M. Azcarate-Peril n, J. Bruno-Barcena, H. Hassan & T. Klaenhammer

Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(11), 3906–3912.

By: E. Altermann, W. Russell, M. Azcarate-Peril n, R. Barrangou, B. Buck n, O. McAuliffe n, N. Souther n, A. Dobson n ...

author keywords: adhesion; stress response; proteolytic system; sugar metabolism; in silico analysis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Functional analysis of putative adhesion factors in Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(12), 8344–8351.

By: B. Buck n, E. Altermann, T. Svingerud n & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2005 journal article

Genetic analysis of two bile salt hydrolase activities in Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(8), 4925–4929.

By: O. McAuliffe n, R. Cano* & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2005 journal article

Genomic Perspectives on Probiotic Lactic Acid Bacteria

Bioscience and Microflora, 24(2), 31–33.

By: T. Klaenhammer, A. Peril n, R. Barrangou, T. Duong & E. Altermann

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2005 review

Genomic features of lactic acid bacteria effecting bioprocessing and health

[Review of ]. FEMS MICROBIOLOGY REVIEWS, 29(3), 393–409.

By: T. Klaenhammer, R. Barrangou, B. Buck n, M. Azcarate-Peril & E. Altermann

author keywords: lactic acid bacteria; genomics; bioprocessing; probiotics; comparative genomics; functional genomics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(8), 2880–2885.

By: M. Mohamadzadeh*, S. Olson*, W. Kalina*, G. Ruthel*, G. Demmin*, K. Warfield*, S. Bavari*, T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2005 journal article

Marker-free chromosomal integration of the manganese superoxide dismutase gene (sodA) from Streptococcus thermophilus into Lactobacillus gasseri

FEMS MICROBIOLOGY LETTERS, 246(1), 91–101.

By: J. Bruno-Barcena, M. Azcarate-Peril, T. Klaenhammer & H. Hassan

author keywords: functional gene replacement; manganese superoxide dismutase; oxidative stress; Lactobacillus gasseri; lactic acid bacteria; probiotics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Microarray analysis of a two-component regulatory system involved in acid resistance and proteolytic activity in Lactobacillus acidophilus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(10), 5794–5804.

Source: Web Of Science
Added: August 6, 2018

2005 review

Modulation of the microbial ecology of the human colon by probiotics, prebiotics and synbiotics to enhance human health: An overview of enabling science and potential applications

[Review of ]. FEMS MICROBIOLOGY ECOLOGY, 52(2), 145–152.

By: R. Rastall*, G. Gibson*, H. Gill*, F. Guarner*, T. Klaenhammer, B. Pot*, G. Reid*, I. Rowland*, M. Sanders*

author keywords: probiotics; prebiotics; synbiotics; colonic microbiota
Source: Web Of Science
Added: August 6, 2018

2005 journal article

PathwayVoyager: pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database

BMC Genomics, 6.

By: E. Altermann & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Sequence analysis of the Lactobacillus plantarum bacteriophage Phi JL-1

GENE, 348, 45–54.

By: Z. Lu*, E. Altermann, F. Breidt n, P. Predki*, H. Fleming* & T. Klaenhammer

author keywords: bacteriophage; Phi JL-1; sequence analysis; structural proteins; Lactobacillus plantarum
Source: Web Of Science
Added: August 6, 2018

2004 patent

Antisense RNA expression strategies effective against Streptococcus thermophilus bacteriophages

Washington, DC: U.S. Patent and Trademark Office.

By: J. Sturino & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Antisense RNA targeting of primase interferes with bacteriophage replication in Streptococcus thermophilus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(3), 1735–1743.

By: J. Sturino & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2004 review

Bacteriophage defense systems and strategies for lactic acid bacteria

[Review of ]. ADVANCES IN APPLIED MICROBIOLOGY, VOL 56, 56, 331-+.

By: J. Sturino & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2004 journal article

DNA analysis of the genes encoding acidocin LF221 A and acidocin LF221 B, two bacteriocins produced by Lactobacillus gasseri LF221

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 63(6), 705–714.

By: A. Majhenic*, K. Venema*, G. Allison*, B. Matijasic*, I. Rogelj* & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2004 journal article

Epidemic clone I-specific genetic markers in strains of Listeria monocytogenes serotype 4b from foods

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(7), 4158–4164.

By: S. Yildirim, W. Lin*, A. Hitchins*, L. Jaykus, E. Altermann, T. Klaenhammer, S. Kathariou

Source: Web Of Science
Added: August 6, 2018

2004 article

Epidemic clone I-specific genetic markers in strains of Listeria monocytogenes serotype 4b from foods (vol 70, pg 4158, 2004)

Yildirim, S., Lin, W., Hitchins, A. D., Jaykus, L. A., Altermann, E., Klaenhammer, T. R., & Kathariou, S. (2004, December). APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol. 70, pp. 7581–7581.

By: S. Yildirim, W. Lin n, A. Hitchins n, L. Jaykus, E. Altermann, T. Klaenhammer, S. Kathariou

Source: Web Of Science
Added: August 6, 2018

2004 journal article

Expression of a heterologous manganese superoxide dismutase gene in intestinal lactobacilli provides protection against hydrogen peroxide toxicity

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(8), 4702–4710.

By: J. Bruno-Barcena, J. Andrus, S. Libby, T. Klaenhammer & H. Hassan

Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Genetic markers unique to Listeria monocytogenes serotype 4b differentiate epidemic clone II (hot dog outbreak strains) from other lineages

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(4), 2383–2390.

By: M. Evans n, B. Swaminathan*, L. Graves*, E. Altermann, T. Klaenhammer, R. Fink, S. Kernodle n, S. Kathariou

Source: Web Of Science
Added: August 6, 2018

2004 journal article

Identification and inactivation of genetic loci involved with Lactobacillus acidophilus acid tolerance

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(9), 5315–5322.

By: M. Azcarate-Peril, E. Altermann, R. Hoover-Fitzula, R. Cano* & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2004 journal article

Identification and phenotypic characterization of the cell-division protein CdpA

GENE, 342(1), 189–197.

By: E. Altermann, B. Buck n, R. Cano* & T. Klaenhammer

author keywords: lactic acid bacteria; lactobacillus; cell adhesion; stress tolerance; functional inactivation; cell wall; cell separation
Source: Web Of Science
Added: August 6, 2018

2004 patent

Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof

Washington, DC: U.S. Patent and Trademark Office.

By: R. Barrangou, T. Klaenhammer & E. Altermann

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101(8), 2512–2517.

By: R. Pridmore n, B. Berger n, F. Desiere n, D. Vilanova n, C. Barretto n, A. Pittet n, M. Zwahlen n, M. Rouvet n ...

Sources: Web Of Science, ORCID
Added: August 6, 2018

2003 journal article

A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes

NUCLEIC ACIDS RESEARCH, 31(7), 1805–1812.

By: R. Roberts*, M. Belfort*, T. Bestor*, A. Bhagwat*, T. Bickle*, J. Bitinaite*, R. Blumenthal*, S. Degtyarev* ...

Source: Web Of Science
Added: August 6, 2018

2003 journal article

Analysis, characterization, and loci of the tuf genes in Lactobacillus and Bifidobacterium species and their direct application for species identification

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 69(11), 6908–6922.

By: M. Ventura*, C. Canchaya*, V. Meylan*, T. Klaenhammer & R. Zink

Source: Web Of Science
Added: August 6, 2018

2003 journal article

Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization by Lactobacillus acidophilus

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(15), 8957–8962.

By: R. Barrangou, E. Altermann, R. Hutkins*, R. Cano* & T. Klaenhammer

Sources: Web Of Science, ORCID
Added: August 6, 2018

2003 journal article

Isolation and characterization of a Lactobacillus plantarum bacteriophage, Phi JL-1, from a cucumber fermentation

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 84(2), 225–235.

By: Z. Lu, F. Breidt, H. Fleming, E. Altermann & T. Klaenhammer

author keywords: bacteriophage; Lactobacillus plantarum; lactic acid bacteria; vegetable fermentation; cucumber fermentation
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Molecular characterization and functional analysis of the manganese-containing superoxide dismutase gene (sodA) from Streptococcus thermophilus AO54

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 420(1), 103–113.

By: J. Andrus, S. Bowen, T. Klaenhammer & H. Hassan

author keywords: Streptococcus thermophilus; superoxide dismutase; MnSOD; sodA sequence; sodA mutant; SOD-null mutant; oxygen sensitivity; manganese ions; DNA polymerase III
Sources: Web Of Science, ORCID
Added: August 6, 2018

2003 patent

Polynucleotide encoding a Lactobacillus gasseri beta-glucuronidase polypeptide

Washington, DC: U.S. Patent and Trademark Office.

By: W. Russell & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Characterization of six Leuconostoc fallax bacteriophages isolated from an industrial sauerkraut fermentation

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 68(11), 5452–5458.

By: R. Barrangou, S. Yoon, F. Breidt, H. Fleming & T. Klaenhammer

Sources: Web Of Science, ORCID
Added: August 6, 2018

2002 journal article

Discovering lactic acid bacteria by genomics

Antonie Van Leeuwenhoek, 82(1-4), 29–58.

By: T. Klaenhammer, E. Altermann, F. Arigoni, A. Bolotin, F. Breidt, J. Broadbent, R. Cano, S. Chaillou ...

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Expression of antisense RNA targeted against Streptococcus thermophilus bacteriophages

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 68(2), 588–596.

By: J. Sturino n & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2002 journal article

Food research trends - 2003 and beyond

Food Technology, 56(12), 30-.

By: N. Mermelstein, O. Fennema, C. Batt, H. Goff, M. Griffiths, D. Hoover, F. Hsieh, V. Juneja ...

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Identification and characterization of Leuconostoc fallax strains isolated from an industrial sauerkraut fermentation

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 68(6), 2877–2884.

By: R. Barrangou, S. Yoon, F. Breidt, H. Fleming & T. Klaenhammer

Sources: Web Of Science, ORCID
Added: August 6, 2018

2002 journal article

Isolation and characterization of bacteriophages from fermenting sauerkraut

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 68(2), 973–976.

By: S. Yoon, R. Barrangou-Poueys n, F. Breidt, T. Klaenhammer & H. Fleming

Sources: Web Of Science, ORCID
Added: August 6, 2018

2002 journal article

Lactococcus lactis lytic bacteriophages of the p335 group are inhibited by overexpression of a truncated CI repressor

JOURNAL OF BACTERIOLOGY, 184(23), 6532–6543.

By: E. Durmaz, S. Madsen n, H. Israelsen n & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2002 journal article

Overexpression of peptidases in Lactococcus and evaluation of their release from leaky cells

JOURNAL OF DAIRY SCIENCE, 85(10), 2438–2450.

By: T. Tuler, M. Callanan & T. Klaenhammer

author keywords: leaky Lactococcus; peptidase
Source: Web Of Science
Added: August 6, 2018

2001 patent

Acid-inducible promoters for gene expression

Washington, DC: U.S. Patent and Trademark Office.

By: M. Kullen & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Analysis of the genetic switch and replication region of a P335-type bacteriophage with an obligate lytic lifestyle on Lactococcus lactis

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 67(3), 1128–1139.

By: S. Madsen*, D. Mills, G. Djordjevic, H. Israelsen* & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2001 journal article

Efficient system for directed integration into the Lactobacillus acidophilus and Lactobacillus gasseri chromosomes via homologous recombination

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 67(9), 4361–4364.

By: W. Russell & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2001 journal article

Identification and cloning of gusA, encoding a new beta-glucuronidase from Lactobacillus gasseri ADH

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 67(3), 1253–1261.

By: W. Russell* & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2001 journal article

Leaky Lactococcus cultures that externalize enzymes and antigens independently of culture lysis and secretion and export pathways

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 67(1), 251–259.

By: S. Walker & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2001 review

The scientific basis of Lactobacillus acidophilus NCFM functionality as a probiotic

[Review of ]. JOURNAL OF DAIRY SCIENCE, 84(2), 319–331.

By: M. Sanders* & T. Klaenhammer

author keywords: Lactobacillus acidophilus NCFM; probiotic; functional food
Source: Web Of Science
Added: August 6, 2018

2000 journal article

An explosive antisense RNA strategy for inhibition of a lactococcal bacteriophage

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 66(1), 310–319.

By: S. Walker & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2000 journal article

Genetic analysis of chromosomal regions of Lactococcus lactis acquired by recombinant lytic phages

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 66(3), 895–903.

By: E. Durmaz & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

2000 journal article

Genetic modification of intestinal lactobacilli and bifidobacteria

Current Issues in Molecular Biology, 2(2), 41.

By: M. Kullen & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Probiotic bacteria: Today and tomorrow

Klaenhammer, T. R. (2000, February). JOURNAL OF NUTRITION, Vol. 130, pp. 415S–416S.

By: T. Klaenhammer

author keywords: probiotics; lactic acid bacteria; lactobacillus; bifidobacterium; dairy
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Use of the DNA sequence of variable regions of the 16S rRNA gene for rapid and accurate identification of bacteria in the Lactobacillus acidophilus complex

JOURNAL OF APPLIED MICROBIOLOGY, 89(3), 511–516.

By: M. Kullen, R. Sanozky-Dawes n, D. Crowell n & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1999 journal article

Colicin V can be produced by lactic acid bacteria

LETTERS IN APPLIED MICROBIOLOGY, 29(1), 37–41.

By: J. McCormick, T. Klaenhammer & M. Stiles*

Source: Web Of Science
Added: August 6, 2018

1999 journal article

Identification of the pH-inducible, proton-translocating F1F0- ATPase (atpBEFHAGDC) operon of Lactobacillus acidophilus by differential display: gene structure, cloning and characterization

Molecular Microbiology, 33(6), 1152–1161.

By: M. Kullen n & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1999 article

Selection and design of probiotics

Klaenhammer, T. R., & Kullen, M. J. (1999, September 15). INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, Vol. 50, pp. 45–57.

By: T. Klaenhammer & M. Kullen n

author keywords: probiotics; Lactobacillus; Bifidobacterium; lactic acid bacteria
Source: Web Of Science
Added: August 6, 2018

1999 journal article

The groESL chaperone operon of Lactobacillus johnsonii

Applied and Environmental Microbiology, 65(7), 3033–3041.

By: D. Walker, H. Girgis & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

A leucine repeat motif in AbiA is required for resistance of Lactococcus lactis to phages representing three species.

GENE, 212(1), 5–11.

By: P. Dinsmore, . DJ O'Sullivan & T. Klaenhammer

author keywords: lactic acid bacteria; phage resistance; leucine zipper; dairy starter cultures
Source: Web Of Science
Added: August 6, 2018

1998 patent

Bacteriophage-triggered cell suicide systems and fermentation methods employing the same

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer, M. Conkling, D. O'Sullivan, G. Djordjevic, S. Walker & C. Taylor

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Common elements regulating gene expression in temperate and lytic bacteriophages of Lactococcus species

Applied and Environmental Microbiology, 64(3), 1147–1152.

By: S. Walker, C. Dombroski & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Control of expression of LlaI restriction in Lactococcus lactis

MOLECULAR MICROBIOLOGY, 27(5), 1009–1020.

By: . DJ O'Sullivan & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1998 article

Functional activities of Lactobacillus probiotics: Genetic mandate

INTERNATIONAL DAIRY JOURNAL, Vol. 8, pp. 497–505.

By: T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1998 review

Inducible gene expression systems in Lactococcus lactis

[Review of ]. MOLECULAR BIOTECHNOLOGY, 9(2), 127–139.

By: G. Djordjevic & T. Klaenhammer

author keywords: Lactococcus; inducible gene expression; starter cultures; bioprocessing
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Molecular characterization of a phage-inducible middle promoter and its transcriptional activator from the lactococcal bacteriophage phi 31

Journal of Bacteriology, 180(4), 921–931.

By: S. Walker & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1998 review

Phage resistance mechanisms in lactic acid bacteria

[Review of ]. INTERNATIONAL DAIRY JOURNAL, 8(3), 207–226.

By: G. Allison & T. Klaenhammer

author keywords: bacteriophage; resistance; defense; abortive infection; restriction; modification; Lactococcus; Streptococcus thermophilus; lactic acid bacteria
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Special issue - Functional foods: Designer foods for the future

International Dairy Journal, 8(5-6), vv.

By: T. Klaenhammer, J. Connolly, R. Fitzgerald, C. Stanton & R. Ross

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

A triggered-suicide system designed as a defense against bacteriophages

JOURNAL OF BACTERIOLOGY, 179(21), 6741–6748.

By: G. Djordjevic, D. OSullivan n, S. Walker, M. Conkling & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1997 journal article

Bacteriophage-triggered defense systems: Phage adaptation and design improvements

Applied and Environmental Microbiology, 63(11), 4370–4376.

By: G. Djordjevic & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1997 review

Genes and gene expression in Lactococcus bacteriophages

[Review of ]. INTERNATIONAL DAIRY JOURNAL, 7(8-9), 489–508.

By: G. Djordjevic & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1997 patent

Method of eliminating genetic routes for bacteriophage evolution and products produced thereby

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer & S. Moineau

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Molecular characterization of a genomic region in a Lactococcus bacteriophage that is involved in its sensitivity to the phage defense mechanism AbiA

JOURNAL OF BACTERIOLOGY, 179(9), 2949–2957.

By: P. Dinsmore & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1997 patent

Phage defense rotation strategy

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer, W. Sing & C. Hill

Source: NC State University Libraries
Added: August 6, 2018

1996 patent

Bacteriophage resistant recombinant bacteria

Washington, DC: U.S. Patent and Trademark Office.

By: C. Hill & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1996 patent

Method of eliminating genetic routes for bacteriophage evolution and products produced thereby

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer & S. Moineau

Source: NC State University Libraries
Added: August 6, 2018

1995 article

Genetics of intestinal lactobacilli

INTERNATIONAL DAIRY JOURNAL, Vol. 5, pp. 1019–1058.

By: T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1993 journal article

Genetics of bacteriocins produced by lactic-acid bacteria

FEMS Microbiology Reviews, 12(39085), 39–86.

By: T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1992 patent

PTR2030, a conjugal plasmid and derivatives thereof that confer phage resistance to group N streptococci

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer, R. Sanozky & L. Steenson

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

A novel rotation strategy using different phage defenses in a single-strain starter culture system

Journal of Dairy Science, 74, 120.

By: T. Klaenhammer & W. Sing

Source: NC State University Libraries
Added: August 6, 2018

1991 article

DEVELOPMENT OF BACTERIOPHAGE-RESISTANT STRAINS OF LACTIC-ACID BACTERIA

KLAENHAMMER, T. R. (1991, August). BIOCHEMICAL SOCIETY TRANSACTIONS, Vol. 19, pp. 675–681.

By: T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1990 patent

pTR2030, a conjugal plasmid and derivatives thereof that confer phage reisistance to group N streptococci

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer, R. Sanozky & L. Steenson

Source: NC State University Libraries
Added: August 6, 2018

1989 journal article

Genetic characterization of multiple mechanisms of phage defense from a prototype phage-insensitive strain, Lactococcus lactis ME2

Journal of Dairy Science, 72(12), 3429.

By: T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1989 patent

pTN1060, a conjugal plasmid and derivatives thereof that confer phage resistance to group N streptococci

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer & R. Sanozky-Dawes

Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

BACTERIOCINS OF LACTIC-ACID BACTERIA

BIOCHIMIE, 70(3), 337–349.

By: T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1987 patent

Lactic acid bacteria which do not decarboxylate malic acid and fermentation therewith

Washington, DC: U.S. Patent and Trademark Office.

By: M. Daeschel, R. McFeeters, H. Fleming, T. Klaenhammer & R. Sanozky

Source: NC State University Libraries
Added: August 6, 2018

1987 journal article

Plasmid-directed mechanisms for bacteriophage defense in lactic streptococci

FEMS Microbiology Reviews, 46(3), 313.

By: T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

CHARACTERIZATION AND PURIFICATION OF HELVETICIN-J AND EVIDENCE FOR A CHROMOSOMALLY DETERMINED BACTERIOCIN PRODUCED BY LACTOBACILLUS-HELVETICUS-481

JOURNAL OF BACTERIOLOGY, 167(2), 439–446.

By: M. Joerger & T. Klaenhammer

Source: Web Of Science
Added: August 6, 2018

1983 journal article

Detection and activity of lactacin-b, a bacteriocin produced by lactobacillus-acidophilus

Applied and Environmental Microbiology, 45(6), 1808–1815.

By: S. Barefoot & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018