Tana Valentina Palomino

College of Sciences

Works (4)

Updated: July 10th, 2024 05:00

2024 article

Mass spectrometry imaging of <i>N</i>-linked glycans: Fundamentals and recent advances

Palomino, T. V., & Muddiman, D. C. (2024, June 27). MASS SPECTROMETRY REVIEWS, Vol. 6.

By: T. Palomino n & D. Muddiman n

author keywords: glycomics; mass spectrometry imaging; N-linked glycans
Sources: Web Of Science, NC State University Libraries
Added: July 8, 2024

2023 journal article

Achieving Cross-Ring Fragmentation of <i>N</i>-Linked Glycans by IR-MALDESI

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 35(1), 166–171.

By: T. Palomino n & D. Muddiman n

author keywords: N-linked glycans; lithium doping; fragmentation; IR-MALDESI; cross-ring fragment
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 16, 2024

2023 journal article

Enhanced Detection of Charged N-Glycans in the Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometric Imaging

ANALYTICAL CHEMISTRY, 95(29), 10913–10920.

By: J. Samal*, T. Palomino n, J. Chen*, D. Muddiman n & T. Segura*

TL;DR: This work demonstrates the first application of IR-MALDESI in N-linked glycan imaging of the brain tissue, leading to a 2.5-fold increase in the in situ total brain N-glycan detection compared to the current gold standard of positive-mode matrix-assisted laser desorption/ionization mass spectrometry imaging. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: July 31, 2023

2023 article

Predicting Sialic Acid Content of N-Linked Glycans Using the Isotopic Pattern of Chlorine

Palomino, T. V., & Muddiman, D. C. (2023, June 8). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 6.

By: T. Palomino n & D. Muddiman n

author keywords: N-linked glycans; sialic acid; chlorine; IR-MALDESI
MeSH headings : Humans; N-Acetylneuraminic Acid; Chlorine; Polysaccharides / chemistry; Sialic Acids / analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: A new rule is described that can predict the number of sialic acids on a glycan and grants confident glycan annotations and compositions beyond accurate mass measurements, thereby further improving the capability of IR-MALDESI to study sialylated N-linked glycans within biological tissues. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 26, 2023

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