@article{burns_bobay_basso_cavanagh_melander_2008, title={Targeting RNA with cysteine-constrained peptides}, volume={18}, ISSN={["0960-894X"]}, DOI={10.1016/j.bmcl.2007.11.096}, abstractNote={A combined approach for targeting RNA with novel, biologically active ligands has been developed using a cyclic peptide library and in silico modeling. This approach has successfully identified novel cyclic peptide constructs that can target bTAR RNA. Subsequently, RNA/peptide interactions were effectively modeled using the HADDOCK docking program.}, number={2}, journal={BIOORGANIC & MEDICINAL CHEMISTRY LETTERS}, author={Burns, Virginia A. and Bobay, Benjamin G. and Basso, Anne and Cavanagh, John and Melander, Christian}, year={2008}, month={Jan}, pages={565–567} } @article{zeng_ballard_tkachenko_burns_feldheim_melander_2006, title={Mimicking the biological activity of diazobenzo[b]fluorene natural products with electronically tuned diazofluorene analogs}, volume={16}, ISSN={["0960-894X"]}, DOI={10.1016/j.bmcl.2006.07.024}, abstractNote={Under appropriate electronic modulation, simple diazofluorene analogs recapitulate the DNA cleavage activity of kinamycin D under thiol-based reducing conditions. Achieving DNA cleavage under these reducing conditions is key to anticancer activity, as the most active compound, 1-methoxydiazofluorene, inhibits the proliferation of HeLa cells.}, number={19}, journal={BIOORGANIC & MEDICINAL CHEMISTRY LETTERS}, author={Zeng, Wei and Ballard, T. Eric and Tkachenko, Alexander G. and Burns, Virginia A. and Feldheim, Daniel L. and Melander, Christian}, year={2006}, month={Oct}, pages={5148–5151} }