Works (5)

Updated: July 5th, 2023 15:52

2008 journal article

BLOOD FLOW IN THE CIRCLE OF WILLIS: MODELING AND CALIBRATION

MULTISCALE MODELING & SIMULATION, 7(2), 888–909.

By: K. Devault n, P. Gremaud*, V. Novak*, M. Olufsen*, G. Vernieres & P. Zhao

author keywords: blood flow; viscoelastic arteries; fluid-structure interaction; Kalman filtering
TL;DR: A numerical model based on one-dimensional balance laws and ad hoc zero-dimensional boundary conditions is tested against experimental data and demonstrates the viability of the proposed approach on the circle of Willis, a vital subnetwork of the cerebral vasculature. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

ESTIMATION AND IDENTIFICATION OF PARAMETERS IN A LUMPED CEREBROVASCULAR MODEL

MATHEMATICAL BIOSCIENCES AND ENGINEERING, 6(1), 93–115.

By: S. Pope n, L. Ellwein*, C. Zapata, V. Novak*, C. Kelley* & M. Olufsen*

author keywords: cardiovascular modeling; systemic resistance; cerebrovascular resistance; parameter estimation; sensitivity analysis; subset selection
MeSH headings : Adult; Aged; Blood Flow Velocity / physiology; Blood Pressure / physiology; Brain / blood supply; Brain / physiology; Cerebral Arteries / physiology; Cerebrovascular Circulation / physiology; Computer Simulation; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Ventricular Function / physiology; Young Adult
TL;DR: The method discussed in this study provides a new methodology to extract clinical markers that cannot easily be assessed noninvasively by using nonlinear optimization combined with sensitivity analysis and subset selection. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 article

Introduction to the special issues: Short-term cardiovascular-respiratory control mechanisms

Batzel, J. J., Novak, V., Kappel, F., Olufsen, M. S., & Tran, H. T. (2008, March). CARDIOVASCULAR ENGINEERING, Vol. 8, pp. 1–4.

By: J. Batzel*, V. Novak*, F. Kappel*, M. Olufsen n & H. Tran n

MeSH headings : Animals; Cardiovascular Physiological Phenomena; Computer Simulation; Feedback / physiology; Humans; Models, Biological; Respiratory Physiological Phenomena
TL;DR: This and the following issue of Cardiovascular Engineering are special issues reflecting research discussed during an interdisciplinary focused workshop entitled Short-term Cardiovascular–Respiratory Control Mechanisms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Modeling heart rate regulation - Part I: Sit-to-stand versus head-up tilt

CARDIOVASCULAR ENGINEERING, 8(2), 73–87.

By: M. Olufsen n, A. Alston n, H. Tran n, J. Ottesen & V. Novak*

author keywords: mathematical modeling; heart rate regulation; sensitivity analysis
MeSH headings : Aged; Baroreflex / physiology; Blood Pressure / physiology; Computer Simulation; Feedback, Physiological / physiology; Female; Head / physiology; Heart Rate / physiology; Humans; Male; Models, Cardiovascular; Posture / physiology; Tilt-Table Test / methods
TL;DR: During head-up tilt, the baseline firing-rate is larger than during sit-to-stand and that the combined effect of vestibular and central command stimulation of muscle sympathetic nerve activity is less pronounced than during sitting to standing. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Sensitivity analysis and model assessment: Mathematical models for arterial blood flow and blood pressure

CARDIOVASCULAR ENGINEERING, 8(2), 94–108.

By: L. Ellwein n, H. Tran n, C. Zapata n, V. Novak n & M. Olufsen n

author keywords: cardiovascular modeling; sensitivity analysis; model reduction; parameter estimation
MeSH headings : Algorithms; Arteries / physiology; Blood Flow Velocity / physiology; Blood Pressure / physiology; Computer Simulation; Diagnosis, Computer-Assisted / methods; Models, Cardiovascular; Posture / physiology; Reproducibility of Results; Sensitivity and Specificity
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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