Works (5)

Updated: July 5th, 2023 15:52

2009 journal article

ESTIMATION AND IDENTIFICATION OF PARAMETERS IN A LUMPED CEREBROVASCULAR MODEL

MATHEMATICAL BIOSCIENCES AND ENGINEERING, 6(1), 93–115.

By: S. Pope n, L. Ellwein*, C. Zapata, V. Novak*, C. Kelley* & M. Olufsen n

author keywords: cardiovascular modeling; systemic resistance; cerebrovascular resistance; parameter estimation; sensitivity analysis; subset selection
MeSH headings : Adult; Aged; Blood Flow Velocity / physiology; Blood Pressure / physiology; Brain / blood supply; Brain / physiology; Cerebral Arteries / physiology; Cerebrovascular Circulation / physiology; Computer Simulation; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Ventricular Function / physiology; Young Adult
TL;DR: The method discussed in this study provides a new methodology to extract clinical markers that cannot easily be assessed noninvasively by using nonlinear optimization combined with sensitivity analysis and subset selection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

BLOOD FLOW IN THE CIRCLE OF WILLIS: MODELING AND CALIBRATION

MULTISCALE MODELING & SIMULATION, 7(2), 888–909.

By: K. Devault n, P. Gremaud*, V. Novak*, M. Olufsen*, G. Vernieres & P. Zhao

author keywords: blood flow; viscoelastic arteries; fluid-structure interaction; Kalman filtering
TL;DR: A numerical model based on one-dimensional balance laws and ad hoc zero-dimensional boundary conditions is tested against experimental data and demonstrates the viability of the proposed approach on the circle of Willis, a vital subnetwork of the cerebral vasculature. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 article

Introduction to the special issues: Short-term cardiovascular-respiratory control mechanisms

Batzel, J. J., Novak, V., Kappel, F., Olufsen, M. S., & Tran, H. T. (2008, March). CARDIOVASCULAR ENGINEERING, Vol. 8, pp. 1–4.

By: J. Batzel*, V. Novak*, F. Kappel*, M. Olufsen n & H. Tran n

MeSH headings : Animals; Cardiovascular Physiological Phenomena; Computer Simulation; Feedback / physiology; Humans; Models, Biological; Respiratory Physiological Phenomena
TL;DR: This and the following issue of Cardiovascular Engineering are special issues reflecting research discussed during an interdisciplinary focused workshop entitled Short-term Cardiovascular–Respiratory Control Mechanisms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Modeling heart rate regulation - Part I: Sit-to-stand versus head-up tilt

CARDIOVASCULAR ENGINEERING, 8(2), 73–87.

By: M. Olufsen n, A. Alston n, H. Tran n, J. Ottesen* & V. Novak*

author keywords: mathematical modeling; heart rate regulation; sensitivity analysis
MeSH headings : Aged; Baroreflex / physiology; Blood Pressure / physiology; Computer Simulation; Feedback, Physiological / physiology; Female; Head / physiology; Heart Rate / physiology; Humans; Male; Models, Cardiovascular; Posture / physiology; Tilt-Table Test / methods
TL;DR: During head-up tilt, the baseline firing-rate is larger than during sit-to-stand and that the combined effect of vestibular and central command stimulation of muscle sympathetic nerve activity is less pronounced than during sitting to standing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Sensitivity analysis and model assessment: Mathematical models for arterial blood flow and blood pressure

CARDIOVASCULAR ENGINEERING, 8(2), 94–108.

By: L. Ellwein n, H. Tran n, C. Zapata n, V. Novak n & M. Olufsen n

author keywords: cardiovascular modeling; sensitivity analysis; model reduction; parameter estimation
MeSH headings : Algorithms; Arteries / physiology; Blood Flow Velocity / physiology; Blood Pressure / physiology; Computer Simulation; Diagnosis, Computer-Assisted / methods; Models, Cardiovascular; Posture / physiology; Reproducibility of Results; Sensitivity and Specificity
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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