@article{vanblunk_srikanth_pandit_kuznetsov_brudno_2023, title={Absorption rate governs cell transduction in dry macroporous scaffolds}, volume={1}, ISSN={["2047-4849"]}, DOI={10.1039/d2bm01753a}, abstractNote={Dry, macroporous scaffolds efficiently transduce T cells, but the mechanism for this transduction has not been studied previously. We report that liquid volume and resultant differences in liquid absorption rates governs cell transduction efficiency.}, journal={BIOMATERIALS SCIENCE}, author={VanBlunk, Madelyn and Srikanth, Vishal and Pandit, Sharda S. and Kuznetsov, Andrey V. and Brudno, Yevgeny}, year={2023}, month={Jan} }
 @article{srikanth_peverall_kuznetsov_2023, title={Flow Regimes and Types of Solid Obstacle Surface Roughness in Turbulent Heat Transfer Inside Periodic Porous Media}, ISSN={["1573-1634"]}, DOI={10.1007/s11242-023-01978-6}, abstractNote={The role of solid obstacle surface roughness in turbulent convection in porous media is not well understood, even though it is frequently used for heat transfer enhancement in many applications. The focus of this paper is to systematically study the influence of solid obstacle surface roughness in porous media on the microscale flow physics and report its effect on macroscale drag and Nusselt number. The Reynolds-averaged flow field is numerically simulated using the realizable k-ε model for a flow through a periodic porous medium consisting of an in-line arrangement of square cylinders with square roughness particles on the cylinder surface. Two flow regimes are identified with respect to the surface roughness particle height—fine and coarse roughness regimes. The effect of the roughness particles in the fine roughness regime is limited to the near-wall boundary layer around the solid obstacle surface. In the coarse roughness regime, the roughness particles modify the microscale flow field in the entire pore space of the porous medium. In the fine roughness regime, the heat transfer from the rough solid obstacles to the fluid inside the porous medium is less than that from a smooth solid obstacle. In the coarse roughness regime, there is an enhancement in the heat transfer from the rough solid obstacle to the fluid inside the porous medium. Total drag reduction is also observed in the fine roughness regime for the smallest roughness particle height. The surface roughness particle spacing determines the fractional area of the solid obstacle surface covered by recirculating, reattached, and stagnating flow. As the roughness particle spacing increases, there are two competing factors for the heat transfer rate—increase due to more surface area covered by reattached flow and decrease due to fewer roughness particles on the solid obstacle surface. Decreasing the porosity and increasing the Reynolds number amplify the effect of the surface roughness on the microscale flow. The results suggest that heat transfer in porous media can be enhanced, if the increase in drag can be overcome. The results also show that the fine roughness regime, which is frequently encountered due to corrosion, is detrimental to the heat transfer performance of porous media.}, journal={TRANSPORT IN POROUS MEDIA}, author={Srikanth, Vishal and Peverall, Dylan and Kuznetsov, Andrey V.}, year={2023}, month={Jul} }
 @article{huang_srikanth_kuznetsov_2022, title={The evolution of turbulent micro-vortices and their effect on convection heat transfer in porous media}, volume={942}, ISSN={["1469-7645"]}, DOI={10.1017/jfm.2022.291}, abstractNote={New insight into the contribution of the microscale vortex evolution to convection heat transfer in porous media is presented in this paper. The objective is to determine how the microscale vortices influence convection heat transfer in turbulent flow inside porous media. The microscale temperature distribution is analysed using flow visualization in two dimensions using streamlines and in three dimensions using the Q-criterion. The pertinent observations are supplemented with a comparison of surface skin friction and heat transfer using: (i) surface skin-friction lines and (ii) the joint probability density function of the pressure and skin-friction coefficients, along with the Nusselt number. The microscale flow phenomena observed are corroborated with the features of the frequency spectra of the drag coefficient and macroscale Nusselt number. The large eddy simulation technique is used in this study to investigate the flow field inside a periodic porous medium. The Reynolds numbers of the flow are 300 and 500. The porous medium consists of solid obstacles in the shape of square and circular cylinders. Two distinct flow regimes are represented by using the porosities of 0.50 and 0.87. The results show that the surface Nusselt number distribution is dependent on whether the micro-vortices are attached to or detached from the surface of the obstacle. The spectra of the macroscale Nusselt number and the pressure drag are similar, signifying a correlation between the dynamics of heat transfer and the microscale turbulent structures. Both vortex shedding and secondary flow instabilities are observed that significantly influence the Nusselt number. The fundamental insight gained in this paper can inform the development of more robust macroscale models of convection heat transfer in turbulent flow in porous media.}, journal={JOURNAL OF FLUID MECHANICS}, author={Huang, Ching-Wei and Srikanth, Vishal and Kuznetsov, Andrey V}, year={2022}, month={May} }
 @article{srikanth_huang_su_kuznetsov_2021, title={Symmetry breaking of turbulent flow in porous media composed of periodically arranged solid obstacles}, volume={929}, ISSN={["1469-7645"]}, DOI={10.1017/jfm.2021.813}, abstractNote={The focus of this paper is a numerical simulation study of the flow dynamics in a periodic porous medium to analyse the physics of a symmetry-breaking phenomenon, which causes a deviation in the direction of the macroscale flow from that of the applied pressure gradient. The phenomenon is prominent in the range of porosity from 0.43 to 0.72 for circular solid obstacles. It is the result of the flow instabilities formed when the surface forces on the solid obstacles compete with the inertial force of the fluid flow in the turbulent regime. We report the origin and mechanism of the symmetry-breaking phenomenon in periodic porous media. Large-eddy simulation (LES) is used to simulate turbulent flow in a homogeneous porous medium consisting of a periodic, square lattice arrangement of cylindrical solid obstacles. Direct numerical simulation is used to simulate the transient stages during symmetry breakdown and also to validate the LES method. Quantitative and qualitative observations are made from the following approaches: (1) macroscale momentum budget and (2) two- and three-dimensional flow visualization. The phenomenon draws its roots from the amplification of a flow instability that emerges from the vortex shedding process. The symmetry-breaking phenomenon is a pitchfork bifurcation that can exhibit multiple modes depending on the local vortex shedding process. The phenomenon is observed to be sensitive to the porosity, solid obstacle shape and Reynolds number. It is a source of macroscale turbulence anisotropy in porous media for symmetric solid-obstacle geometries. In the macroscale, the principal axis of the Reynolds stress tensor is not aligned with any of the geometric axes of symmetry, nor with the direction of flow. Thus, symmetry breaking in porous media involves unresolved flow physics that should be taken into consideration while modelling flow inhomogeneity in the macroscale.}, journal={JOURNAL OF FLUID MECHANICS}, author={Srikanth, Vishal and Huang, Ching-Wei and Su, Timothy S. and Kuznetsov, Andrey V}, year={2021}, month={Oct} }