William Laubach Miller

Works (30)

Updated: April 4th, 2024 21:11

2021 journal article

Impact of Ceftiofur Administration in Steers on the Prevalence and Antimicrobial Resistance of Campylobacter spp.

MICROORGANISMS, 9(2).

By: S. Fan n, D. Foster n, W. Miller*, J. Osborne n & S. Kathariou n

author keywords: ceftiofur; CCFA; CHCL; cattle; Campylobacter; antibiotic resistance
TL;DR: It is suggested that CCFA or CHCL may be preferable due to the lower likelihood of temporary increases in Campylobacter prevalence and ceftiofur minimum inhibitory concentration (MIC) for C. jejuni, respectively. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 15, 2021

2020 article

Cultural Entanglements: Langston Hughes and the Rise of African and Caribbean Literature

Miller, W. J. (2021, February 1). MODERN PHILOLOGY, Vol. 118, pp. E224–E226.

By: W. Miller n

Source: Web Of Science
Added: February 22, 2021

2019 journal article

Strain-Specific Differences in Survival of Campylobacter spp. in Naturally Contaminated Turkey Feces and Water

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 85(22).

By: L. Good n, W. Miller*, J. Niedermeyer n, J. Osborne n, R. Siletzky n, D. Carver n, S. Kathariou n

author keywords: Campylobacter; Campylobacter coli; Campylobacter jejuni; turkey; antimicrobial resistance; feces; survival; water
MeSH headings : Animals; Bacterial Typing Techniques; Campylobacter / classification; Campylobacter / physiology; Campylobacter Infections / microbiology; Campylobacter Infections / veterinary; Campylobacter coli / physiology; Campylobacter jejuni / physiology; Cold Temperature; Drug Resistance, Multiple, Bacterial; Feces / microbiology; Microbial Viability; Multilocus Sequence Typing; Polymorphism, Restriction Fragment Length; Turkeys; Water Microbiology
TL;DR: Examination of survival of Campylobacter, including different strains, in freshly excreted feces from naturally colonized commercial turkey flocks and in suspensions of turkey feces in water from the turkey house revealed that C. jejuni survived longer than C. coli in feces, while the reverse was observed in water. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 16, 2019

2018 journal article

Clinical therapeutic efficacy of mycophenolate mofetil in the treatment of SARDS in dogs-a prospective open-label pilot study

VETERINARY OPHTHALMOLOGY, 21(6), 565–576.

By: W. Young n, A. Oh n, J. Williams n, M. Foster n, W. Miller*, K. Lunn n, F. Mowat n

author keywords: dog; mycophenolate mofetil; retina; sudden acquired retinal degeneration syndrome; treatment; vision
MeSH headings : Animals; Dog Diseases / drug therapy; Dogs; Female; Immunosuppressive Agents / therapeutic use; Male; Mycophenolic Acid / therapeutic use; Pilot Projects; Prospective Studies; Retinal Degeneration / drug therapy; Retinal Degeneration / veterinary; Vision Tests / veterinary
TL;DR: The effect of sole-agent treatment with mycophenolate mofetil as a sole agent has no measureable positive effect on physical health, vision, or retinal structure following a 6-week trial period. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 3, 2018

2018 journal article

Proximity to Other Commercial Turkey Farms Affects Colonization Onset, Genotypes, and Antimicrobial Resistance Profiles of Campylobacter spp. in Turkeys: Suggestive Evidence from a Paired-Farm Model

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 84(18).

By: J. Niedermeyer n, L. Ring n, W. Miller*, S. Genger n, C. Lindsey n, J. Osborne n, S. Kathariou n

author keywords: Campylobacter; antimicrobial resistance; colonization; genotype; turkey
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Campylobacter / drug effects; Campylobacter / genetics; Campylobacter / growth & development; Campylobacter / isolation & purification; Campylobacter Infections / economics; Campylobacter Infections / microbiology; Campylobacter Infections / veterinary; Drug Resistance, Bacterial; Farms / economics; Genotype; Models, Biological; Multilocus Sequence Typing; North Carolina; Poultry Diseases / economics; Poultry Diseases / microbiology; Turkeys / microbiology
TL;DR: A paired-farm design was used to concurrently investigate Campylobacter colonization and strain types in two turkey breeds at two farms in eastern North Carolina, highlighting the need to further characterize the impact of farm-specific factors and host genetics on antimicrobial resistance and genotypes of C. jejuni and C. coli that colonize turkeys. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 19, 2018

2015 journal article

Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 419(C), 124–138.

By: H. Wang, R. Hastings, W. Miller n & T. Kumar*

author keywords: Pituitary; Gonadotrope; Cre; Dicer; Testis; Ovary
MeSH headings : Animals; Cattle; DEAD-box RNA Helicases / genetics; DEAD-box RNA Helicases / metabolism; Female; Fertility; Follicle Stimulating Hormone, beta Subunit / genetics; Gonadotrophs / metabolism; Integrases / metabolism; Male; Mice; Mice, Transgenic; Promoter Regions, Genetic; Ribonuclease III / genetics; Ribonuclease III / metabolism
TL;DR: Fshb-iCre mice serve as a new genetic tool to efficiently manipulate gonadotrope-specific gene expression in vivo and it is shown that loss of DICER-dependent miRNAs in gonadotropes leads to profound suppression of Gonadotropins resulting in male and female infertility. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Redirecting intracellular trafficking and the secretion pattern of FSH dramatically enhances ovarian function in mice

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(15), 5735–5740.

By: H. Wang, M. Larson, A. Jablonka-Shariff*, C. Pearl*, W. Miller n, P. Conn*, I. Boime*, T. Kumar*

author keywords: protein sorting; regulated secretion; dense core granules; folliculogenesis
MeSH headings : Analysis of Variance; Animals; Biological Evolution; Blotting, Western; Female; Fertility / physiology; Follicle Stimulating Hormone / metabolism; Gonadotrophs / metabolism; Luteinizing Hormone / metabolism; Mice; Mice, Transgenic; Microscopy, Confocal; Microscopy, Immunoelectron; Ovarian Follicle / metabolism; Ovary / metabolism; Ovary / physiology; Ovulation / metabolism; Real-Time Polymerase Chain Reaction; Signal Transduction / physiology
TL;DR: The rerouted FSH enhanced ovarian follicle survival, caused a dramatic increase in number of ovulations, and prolonged female reproductive lifespan, and the approach to interconvert the secretory fate of proteins in vivo has pathophysiological significance, and could explain the etiology of several hormone hyperstimulation and resistance syndromes. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Gonadotrope-Specific Expression and Regulation of Ovine Follicle Stimulating Hormone Beta: Transgenic and Adenoviral Approaches Using Primary Murine Gonadotropes

PLOS ONE, 8(7).

By: J. Jia*, F. Shafiee-Kermani n & W. Miller n

MeSH headings : Adenoviridae; Analysis of Variance; Animals; DNA Primers / genetics; Enhancer Elements, Genetic / genetics; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Gene Expression Regulation / physiology; Gonadotrophs / metabolism; Luciferases; Mice; Mice, Transgenic; Promoter Regions, Genetic / genetics; Real-Time Polymerase Chain Reaction; Sheep / genetics; Sheep / physiology
TL;DR: It is concluded that adenoviral-based studies in primary gonadotropes can adequately recognize regulatory elements on the ovine FSHB promoter associated with gonadotrope-specific regulation/expression, but that more physiologically based techniques will be needed to identify sequences between −1866/−750 bp of the Ovine F SHB promoter that are also required for tissue/cell specific expression in vivo. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Activin A induces ovine follicle stimulating hormone beta using-169/-58 bp of its promoter and a simple TATA box

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 7.

By: S. Han n & W. Miller n

MeSH headings : Activins / pharmacology; Animals; Base Sequence; Follicle Stimulating Hormone, beta Subunit / biosynthesis; Follicle Stimulating Hormone, beta Subunit / genetics; Gonadotrophs / metabolism; Mice; Promoter Regions, Genetic / genetics; Rats; Sheep; TATA Box
Source: Web Of Science
Added: August 6, 2018

2009 patent

Increasing gamete production with a gene switch

By: W. Miller

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Chronic gonadotropin-releasing hormone inhibits activin induction of the ovine follicle-stimulating hormone beta-subunit: Involvement of 3 ',5 '-cyclic adenosine monophosphate response element binding protein and nitric oxide synthase type I

ENDOCRINOLOGY, 148(7), 3346–3355.

By: F. Shafiee-Kermani n, S. Han n & W. Miller n

MeSH headings : Activins / pharmacology; Animals; Cell Line; Colforsin / pharmacology; Cyclic AMP Response Element-Binding Protein / genetics; Cyclic AMP Response Element-Binding Protein / metabolism; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Follistatin / genetics; Follistatin / metabolism; Gene Expression / drug effects; Gonadotropin-Releasing Hormone / pharmacology; Humans; Luciferases / genetics; Luciferases / metabolism; Male; Mice; Mice, Transgenic; Nitric Oxide Synthase Type I / genetics; Nitric Oxide Synthase Type I / metabolism; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate / pharmacology; Time Factors
TL;DR: The concept that chronic GnRH inhibits activin-induced ovine FSHB expression by sequential activation of CREB and NOSI through the cAMP and/or protein kinase C pathways is supported. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Expression and regulation of the beta-subunit of ovine follicle-stimulating hormone relies heavily on a promoter sequence likely to bind smad-associated proteins

ENDOCRINOLOGY, 148(9), 4500–4508.

By: P. Su n, F. Shafiee-Kermani n, A. Gore n, J. Jia n, J. Wu n & W. Miller n

MeSH headings : Animals; Follicle Stimulating Hormone / genetics; Follicle Stimulating Hormone, beta Subunit / genetics; Gene Expression Regulation; Promoter Regions, Genetic; Sheep; Smad Proteins / genetics
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Conditional induction of ovulation in mice

BIOLOGY OF REPRODUCTION, 73(4), 681–687.

By: P. Su*, J. Wu n, . Sommer n, A. Gore n, R. Petters n & W. Miller n

author keywords: assisted reproductive technology; anterior pituitary; follicle-stimulating hormone; gene regulation; ovulation
MeSH headings : Animals; Cells, Cultured; Doxycycline / pharmacology; Female; Follicle Stimulating Hormone / blood; Follicle Stimulating Hormone / genetics; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Genetic Engineering / methods; Male; Mice; Mice, Transgenic; Ovary / drug effects; Ovary / physiology; Ovulation / drug effects; Ovulation / genetics; Ovulation / physiology; Ovulation Induction / methods; Superovulation / genetics
TL;DR: In summary, gene switch technology and normal FSH regulation were combined to effectively enhance ovulation in mice and the same strategy can be used with any genetic switch to increase ovulation (or any highly conserved physiology) in any mammal. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Differential regulation of follicle stimulating hormone by activin A and TGFB1 in murine gonadotropes

Reproductive Biology and Endocrinology, 3.

By: A. Gore, D. Philips, W. Miller & D. Bernard

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression

ENDOCRINOLOGY, 146(11), 4814–4824.

By: N. Safwat n, J. Ninomiya-Tsuji n, A. Gore n & W. Miller n

Contributors: N. Safwat n, J. Ninomiya-Tsuji n, A. Gore n & W. Miller n

MeSH headings : Activins / pharmacology; Animals; Cell Line; Enzyme Activation / physiology; Follicle Stimulating Hormone, beta Subunit / antagonists & inhibitors; Follicle Stimulating Hormone, beta Subunit / biosynthesis; Follicle Stimulating Hormone, beta Subunit / genetics; Follicle Stimulating Hormone, beta Subunit / metabolism; Humans; Inhibin-beta Subunits / pharmacology; Kinetics; Lactones / pharmacology; Luciferases / genetics; MAP Kinase Kinase Kinases / metabolism; Phosphorylation; Recombinant Fusion Proteins / biosynthesis; Recombinant Proteins / pharmacology; Resorcinols / pharmacology; Sheep; Transfection; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: This study used 4.7 kb of the ovine FSHβ-promoter linked to luciferase (oFSHβLuc) plus a well-characterized activin-responsive construct, p3TPLuc, to investigate the hypothesis that Smad3, TGFβ-activated kinase 1 (TAK1), or both cause activationin-mediated induction of FSH. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

Rapid, efficient isolation of murine gonadotropes and their use in revealing control of follicle-stimulating hormone by paracrine pituitary factors

ENDOCRINOLOGY, 145(12), 5832–5839.

By: J. Wu n, P. Su*, N. Safwat*, J. Sebastian* & W. Miller*

MeSH headings : Activins / pharmacology; Animals; Cell Separation / methods; Follicle Stimulating Hormone / metabolism; Follistatin / pharmacology; Luteinizing Hormone / metabolism; Mice; Mice, Inbred Strains; Mice, Transgenic; Paracrine Communication / drug effects; Paracrine Communication / physiology; Pituitary Gland / cytology; Pituitary Gland / metabolism
TL;DR: Data show that paracrine factors from pituitary nongonadotropes can play a major role in controlling FSHbeta at the pituitaries level, including all cells that produce endocrine hormones. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Pituitary tumorigenesis targeted by the ovine follicle-stimulating hormone beta-subunit gene regulatory region in transgenic mice

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 203(1-2), 169–183.

By: F. Pernasetti*, T. Spady*, S. Hall*, S. Rosenberg*, M. Givens*, S. Anderson*, M. Paulus*, W. Miller n, P. Mellon*

author keywords: follicle-stimulating hormone; gonadotrope; T antigen; tumors; transgenic mice
MeSH headings : Animals; Antigens, Polyomavirus Transforming / genetics; Basophils / pathology; Cell Differentiation; Cell Division; Female; Fertility; Follicle Stimulating Hormone / blood; Follicle Stimulating Hormone, beta Subunit / genetics; Gonads / metabolism; Gonads / pathology; Male; Mice; Mice, Transgenic; Mitotic Index; Pituitary Gland / pathology; Pituitary Hormones / biosynthesis; Pituitary Neoplasms / etiology; Pituitary Neoplasms / pathology; Seminiferous Tubules / pathology; Sheep
TL;DR: These animals offer a unique and potentially useful model of organ-specific tumorigenesis, where a multistage pathway of tumor development is evident, both histologically and temporally. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 review

The nature of FSH induction by GnRH

[Review of ]. TRENDS IN ENDOCRINOLOGY AND METABOLISM, 13(6), 257–263.

By: W. Miller n, F. Shafiee-Kermani n, B. Strahl* & H. Huang*

MeSH headings : Animals; Enhancer Elements, Genetic; Follicle Stimulating Hormone / biosynthesis; Follicle Stimulating Hormone, beta Subunit / biosynthesis; Follicle Stimulating Hormone, beta Subunit / genetics; Gene Expression / drug effects; Gonadotropin-Releasing Hormone / pharmacology; Humans; Mice; Mice, Transgenic; Promoter Regions, Genetic; Transcription, Genetic / drug effects; Transforming Growth Factor beta / pharmacology
TL;DR: Past studies on GnRH induction of FSH are summarized, questions and approaches for the future are proposed, and the ability to express FSHB promoter-reporter constructs in transgenic mouse gonadotropes to test the physiological relevance of promoter elements identified by using L beta T2 cells is proposed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2001 journal article

A novel role for bone morphogenetic proteins in the synthesis of follicle-stimulating hormone

ENDOCRINOLOGY, 142(6), 2275–2283.

By: H. Huang n, J. Wu, P. Su, O. Zhirnov & W. Miller

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the L beta T2 pituitary gonadotrope cell model

ENDOCRINOLOGY, 142(6), 2284–2295.

By: F. Pernasetti*, . Vasilyev, S. Rosenberg, J. Bailey, H. Huang, W. Miller, P. Mellon

Source: Web Of Science
Added: August 6, 2018

2001 journal article

The promoter for the ovine follicle-stimulating hormone-beta gene (FSH beta) confers FSH beta-like expression on luciferase in transgenic mice: Regulatory studies in vivo and in vitro

ENDOCRINOLOGY, 142(6), 2260–2266.

By: H. Huang n, J. Sebastian, B. Strahl, J. Wu & W. Miller

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Transcriptional regulation of the ovine follicle-stimulating hormone-beta gene by activin and gonadotropin-releasing hormone (GnRH): Involvement of two proximal activator protein-1 sites for GnRH stimulation

ENDOCRINOLOGY, 142(6), 2267–2274.

By: H. Huang n, J. Sebastian, B. Strahl, J. Wu & W. Miller

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Estradiol induces and hyperglycosylates the receptor for ovine gonadotropin-releasing hormone

ENDOCRINOLOGY, 141(1), 91–99.

By: D. Gardner n, J. Sebastian & W. Miller

TL;DR: The photoaffinity technique has been used here to further investigate estradiol-mediated induction of GnRHRec, define the nature of the different sized Gn RHRecs, and determine whether the larger size is related to degradation of the LH response. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Antimicrobial activity in the skin of the channel catfish Ictalurus punctatus: characterization of broad-spectrum histone-like antimicrobial proteins

CELLULAR AND MOLECULAR LIFE SCIENCES, 54(5), 467–475.

By: D. Robinette n, S. Wada n, T. Arroll n, M. Levy n, W. Miller n & E. Noga n

author keywords: antimicrobial proteins; catfish; non-specific immunity; histones
MeSH headings : Aeromonas / drug effects; Amino Acid Sequence; Animals; Anti-Bacterial Agents / isolation & purification; Anti-Bacterial Agents / pharmacology; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Fish Diseases / immunology; Histones / chemistry; Ictaluridae / immunology; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Oomycetes / drug effects; Proteins / isolation & purification; Proteins / pharmacology; Skin / chemistry; Skin / microbiology
TL;DR: Mass spectrometry, amino acid composition and amino acid sequence data suggest that the most abundant protein is closely related to histone H2B, and suggest that histones may be important defensive molecules in fish. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Transcriptional activation of the ovine follicle-stimulating hormone beta-subunit gene by gonadotropin-releasing hormone: Involvement of two activating protein-1-binding sites and protein kinase C

ENDOCRINOLOGY, 139(11), 4455–4465.

By: B. Strahl*, H. Huang, J. Sebastian, B. Ghosh & W. Miller

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Differential effects of inhibin on gonadotropin stores and gonadotropin-releasing hormone binding to pituitary cells from cycling female rats

ENDOCRINOLOGY, 138(4), 1577–1584.

By: G. Childs*, B. Miller & W. Miller

Source: Web Of Science
Added: August 6, 2018

1997 journal article

Two proximal activating protein-1-binding sites are sufficient to stimulate transcription of the ovine follicle-stimulating hormone-beta gene

ENDOCRINOLOGY, 138(6), 2621–2631.

By: B. Strahl n, H. Huang, N. Pedersen, J. Wu, B. Ghosh & W. Miller

Source: Web Of Science
Added: August 6, 2018

1993 chapter

Regulation of pituitary gonadotropins by gonadotropin-releasing hormone, estradiol, progesterone, inhibin, and activin

In Genes in mammalian reproduction (p. 247). New York : Wiley-Liss.

By: W. Miller

Source: NC State University Libraries
Added: August 6, 2018

1985 journal article

SECRETION OF OVINE LUTEINIZING-HORMONE INVITRO - DIFFERENTIAL POSITIVE CONTROL BY 17-BETA-ESTRADIOL AND A PREPARATION OF PORCINE OVARIAN INHIBIN

ENDOCRINOLOGY, 117(3), 907–911.

By: W. Miller n & E. Huang n

MeSH headings : Animals; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol / pharmacology; Female; Gonadotropin-Releasing Hormone / analogs & derivatives; Gonadotropin-Releasing Hormone / pharmacology; Inhibins / pharmacology; Kinetics; Luteinizing Hormone / metabolism; Radioimmunoassay; Sheep; Swine; Time Factors; Triptorelin Pamoate / analogs & derivatives
TL;DR: Two types of LH secretory control may be physiologically important, at least in sheep, and perhaps in other animals as well, and study of these phenomena may uncover novel molecular details governing LHRH-stimulated LH release. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1981 journal article

ANTI-ESTROGENS AND OVINE GONADOTROPHS - ANTAGONISM OF ESTROGEN-INDUCED CHANGES IN GONADOTROPIN SECRETIONS

ENDOCRINOLOGY, 108(1), 96–102.

By: W. Miller n & E. Huang n

MeSH headings : Animals; Estradiol / pharmacology; Estrogen Antagonists / pharmacology; Female; Follicle Stimulating Hormone / metabolism; Gonadotropin-Releasing Hormone / pharmacology; Gonadotropins / metabolism; Gonadotropins / pharmacology; Luteinizing Hormone / metabolism; Pituitary Gland / metabolism; Sheep; Tamoxifen / pharmacology
TL;DR: Long term ovine pituitary cell cultures have provided a useful in vitro system for testing the biological potencies of AE analogs, and AEs appeared to act as pure estrogen antagonists in ovine gonadotrophs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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