William Polacheck

Rathod, M. L., Aw, W. Y., Huang, S., Lu, J., Doherty, E. L., Whithworth, C. P., … Polacheck, W. J. (2024, January 7). Donor-Derived Engineered Microvessels for Cardiovascular Risk Stratification of Patients with Kidney Failure. SMALL. https://doi.org/10.1002/smll.202307901

Aw, W. Y., Cho, C., Wang, H., Cooper, A. H., Doherty, E. L., Rocco, D., … Polacheck, W. J. (2023). Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation. SCIENCE ADVANCES, 9(7). https://doi.org/10.1126/sciadv.ade8939

Doherty, E. L., Aw, W. Y., Warren, E. C., Hockenberry, M., Whitworth, C. P., Krohn, G., … Polacheck, W. J. (2023). Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics. ACTA BIOMATERIALIA, 166, 346–359. https://doi.org/10.1016/j.actbio.2023.05.015

Whitworth, C. P., & Polacheck, W. J. (2023, December 22). Vascular organs-on-chip made with patient-derived endothelial cells: technologies to transform drug discovery and disease modeling. EXPERT OPINION ON DRUG DISCOVERY. https://doi.org/10.1080/17460441.2023.2294947

Chhabra, A., Song, H.-H. G., Grzelak, K. A., Polacheck, W. J., Fleming, H. E., Chen, C. S., & Bhatia, S. N. (2022). A vascularized model of the human liver mimics regenerative responses. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(28). https://doi.org/10.1073/pnas.2115867119

Lee, G.-hun, Huang, S. A., Aw, W. Y., Rathod, M. L., Cho, C., Ligler, F. S., & Polacheck, W. J. (2022). Multilayer microfluidic platform for the study of luminal, transmural, and interstitial flow. BIOFABRICATION, 14(2). https://doi.org/10.1088/1758-5090/ac48e5

Wang, W. Y., Kent, R. N., III, Huang, S. A., Jarman, E. H., Shikanov, E. H., Davidson, C. D., … Baker, B. M. (2021). Direct comparison of angiogenesis in natural and synthetic biomaterials reveals that matrix porosity regulates endothelial cell invasion speed and sprout diameter. ACTA BIOMATERIALIA, 135, 260–273. https://doi.org/10.1016/j.actbio.2021.08.038

Rickard, B. P., Conrad, C., Sorrin, A. J., Ruhi, M. K., Reader, J. C., Huang, S. A., … Rizvi, I. (2021). [Review of Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response]. CANCERS, 13(17). https://doi.org/10.3390/cancers13174318

Perez-Rodriguez, S., Huang, S. A., Borau, C., Manuel Garcia-Aznar, J., & Polacheck, W. J. (2021). Microfluidic model of monocyte extravasation reveals the role of hemodynamics and subendothelial matrix mechanics in regulating endothelial integrity. BIOMICROFLUIDICS, 15(5). https://doi.org/10.1063/5.0061997

Du, Y., Khandekar, G., Llewellyn, J., Polacheck, W., Chen, C. S., & Wells, R. G. (2020). A Bile Duct-on-a-Chip With Organ-Level Functions. HEPATOLOGY, 71(4), 1350–1363. https://doi.org/10.1002/hep.30918

Wang, W. Y., Lin, D., Jarman, E. H., Polacheck, W. J., & Baker, B. M. (2020). Functional angiogenesis requires microenvironmental cues balancing endothelial cell migration and proliferation. LAB ON A CHIP, 20(6), 1153–1166. https://doi.org/10.1039/c9lc01170f

Griffith, C. M., Huang, S. A., Cho, C., Khare, T. M., Rich, M., Lee, G.-hun, … Polacheck, W. J. (2020). Microfluidics for the study of mechanotransduction. JOURNAL OF PHYSICS D-APPLIED PHYSICS, 53(22). https://doi.org/10.1088/1361-6463/ab78d4

Polacheck, W. J., Kutys, M. L., Tefft, J. B., & Chen, C. S. (2019). Microfabricated blood vessels for modeling the vascular transport barrier. NATURE PROTOCOLS, 14(5), 1425–1454. https://doi.org/10.1038/s41596-019-0144-8