Wujin Sun
Works (34)
Updated: July 20th, 2023 21:13
2020 journal article
CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation
SCIENCE ADVANCES, 6(21).
MeSH headings : CRISPR-Cas Systems; Cholesterol; DNA / genetics; DNA / metabolism; Gene Editing; Polymers / metabolism; Proprotein Convertase 9 / genetics; Proprotein Convertase 9 / metabolism; RNA / genetics; Ribonucleoproteins / genetics
advances.sciencemag.org (publisher PDF)
Source: Web Of Science
Added: June 22, 2020
2020 review
Non-transdermal microneedles for advanced drug delivery
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 165-166, 41–59.
author keywords: Microneedle; Implant; Drug delivery; Non-transdermal; Biocompatibility; Biodegradability
MeSH headings : Administration, Topical; Biological Transport; Drug Delivery Systems / methods; Equipment Design; Humans; Microinjections / instrumentation; Microinjections / methods; Microtechnology / methods; Polymers; Prostheses and Implants
Source: Web Of Science
Added: January 11, 2021
2019 journal article
Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs
SCIENCE ADVANCES, 5(7).
MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems; Insulin / administration & dosage; Mice; Molecular Structure; Polymers / chemical synthesis; Polymers / chemistry; Swine
Source: Web Of Science
Added: August 19, 2019
2019 article
Topical and Transdermal Nanomedicines for Cancer Therapy
NANOTHERANOSTICS FOR CANCER APPLICATIONS, Vol. 5, pp. 231–251.
Source: Web Of Science
Added: October 26, 2020
2018 journal article
Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy
NATURE BIOMEDICAL ENGINEERING, 2(11), 831–840.
MeSH headings : Animals; Antibodies / chemistry; Antibodies / immunology; Blood Platelets / chemistry; Blood Platelets / cytology; Blood Platelets / metabolism; Cell Line, Tumor; Chemokines / metabolism; Cytokines / metabolism; Disease Models, Animal; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells / chemistry; Hematopoietic Stem Cells / cytology; Hematopoietic Stem Cells / metabolism; Leukemia / therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Receptor / deficiency; Programmed Cell Death 1 Receptor / genetics; Programmed Cell Death 1 Receptor / immunology; T-Lymphocytes / cytology; T-Lymphocytes / immunology; T-Lymphocytes / metabolism
Source: Web Of Science
Added: November 26, 2018
2017 journal article
Anaerobe-Inspired Anticancer Nanovesicles
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(10), 2588–2593.
author keywords: drug delivery; nanomedicines; photodynamic therapy
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Cell Death / drug effects; Cell Proliferation / drug effects; Clostridium / chemistry; Clostridium / metabolism; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Hypoxia / metabolism; Imidazoles / chemistry; Imidazoles / pharmacology; Nanoparticles / chemistry; Prodrugs / chemistry; Prodrugs / pharmacology; Salmonella / chemistry; Salmonella / metabolism; Tirapazamine / chemistry; Tirapazamine / pharmacology
Source: Web Of Science
Added: August 6, 2018
2017 review
Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs
[Review of ]. THERANOSTICS, 7(14), 3504–3516.
author keywords: artificial immune cells; lymphoid organs
MeSH headings : Animals; Antigen-Presenting Cells / immunology; Artificial Cells / chemistry; Artificial Cells / immunology; Biomimetic Materials / chemistry; Humans; Lymphoid Tissue / cytology; Lymphoid Tissue / immunology
Source: Web Of Science
Added: August 6, 2018
2017 journal article
In vivo multienzyme complex coconstruction of N-Acetylneuraminic acid lyase and N-Acetylglucosamine-2-epimerase for Biosynthesis of N-Acetylneuraminic acid
Journal of Agricultural and Food Chemistry, 65(34), 7467–7475.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Insulin-responsive glucagon delivery for prevention of hypoglycemia
Small (Weinheim An Der Bergstrasse, Germany), 13(19).
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Red Blood Cells for Glucose-Responsive Insulin Delivery
ADVANCED MATERIALS, 29(18).
MeSH headings : Erythrocytes; Glucose; Insulin
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy
ADVANCED MATERIALS, 29(13).
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Biomimetic Materials / chemistry; Blood Vessels / drug effects; Blood Vessels / metabolism; Cell Line, Tumor; Cell Survival / drug effects; Cells, Cultured; Dextrans / chemistry; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells / drug effects; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Mice, Nude; Microtubules / enzymology; Microtubules / metabolism; Nanostructures / chemistry; Neoplasm Transplantation; Neoplasms / blood supply; Neoplasms / drug therapy; Neoplasms / metabolism; Oligopeptides / chemistry; Paclitaxel / administration & dosage; Paclitaxel / pharmacokinetics; Tumor Necrosis Factor-alpha / chemistry; Tumor Necrosis Factor-alpha / pharmacokinetics
Source: Web Of Science
Added: August 6, 2018
2017 review
Tailoring non-viral delivery vehicles for transporting genome-editing tools
[Review of ]. Science China-Materials, 60(6), 511–515.
Source: NC State University Libraries
Added: August 6, 2018
2016 article
ATP-Responsive Drug Delivery Systems
Sun, W., & Gu, Z. (2016, March 3). EXPERT OPINION ON DRUG DELIVERY, Vol. 13, pp. 311–314.
MeSH headings : Adenosine Triphosphate / metabolism; Drug Carriers / chemistry; Drug Delivery Systems; Humans
Source: Web Of Science
Added: August 6, 2018
2016 journal article
ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging
THERANOSTICS, 6(7), 1053–1064.
author keywords: drug delivery; nanomedicine; stimuli-responsive; ATP-responsive; theranostics; conjugated polymers
MeSH headings : Adenosine Triphosphate / metabolism; Antineoplastic Agents / administration & dosage; Boronic Acids / metabolism; Doxorubicin / administration & dosage; Drug Carriers / administration & dosage; Hep G2 Cells; Humans; Liver Neoplasms / diagnostic imaging; Liver Neoplasms / drug therapy; Nanoparticles / administration & dosage; Optical Imaging / methods; Theranostic Nanomedicine / methods
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Dual targeted nanocarrier for brain ischemic stroke treatment
JOURNAL OF CONTROLLED RELEASE, 233, 64–71.
author keywords: Stroke; Stroke homing peptide; Dual-targeting liposomes; ZL006; Neuroprotection
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus
ADVANCED MATERIALS, 28(43), 9573-+.
MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / pharmacokinetics; Biomimetics; Blood Platelets / cytology; Bone and Bones / metabolism; Cell Line, Tumor; Cell Membrane / metabolism; Cellular Microenvironment; Disease Models, Animal; Drug Carriers / chemistry; Drug Carriers / pharmacokinetics; Humans; Mice; Multiple Myeloma / complications; Multiple Myeloma / drug therapy; Multiple Myeloma / metabolism; Multiple Myeloma / pathology; Nanoparticles / chemistry; Thrombosis / complications; Thrombosis / drug therapy
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody
ADVANCED MATERIALS, 28(40), 8912–8920.
MeSH headings : Adjuvants, Immunologic; Animals; Antibodies; CpG Islands; Immunotherapy; Inflammation; Mice; Neoplasms / therapy; Programmed Cell Death 1 Receptor / immunology
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Internalized compartments encapsulated nanogels for targeted drug delivery
NANOSCALE, 8(17), 9178–9184.
MeSH headings : Doxorubicin / administration & dosage; Drug Delivery Systems; Ferrous Compounds; Hyaluronic Acid; Nanoparticles; Silicon Dioxide
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy
ADVANCED MATERIALS, 28(17), 3313–3320.
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Cell Hypoxia; Cell Survival / drug effects; Doxorubicin / chemistry; Doxorubicin / pharmacology; Doxorubicin / therapeutic use; Drug Carriers / chemistry; HeLa Cells; Humans; Hydrogen-Ion Concentration; Light; Mice; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanoparticles / chemistry; Neoplasms / diagnostic imaging; Neoplasms / drug therapy; Neoplasms / pathology; Optical Imaging; Polyvinyl Alcohol / chemistry; Singlet Oxygen / chemistry; Singlet Oxygen / metabolism; Transplantation, Heterologous
Source: Web Of Science
Added: August 6, 2018
2016 review
Recent advances of cocktail chemotherapy by combination drug delivery systems
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 98, 19–34.
author keywords: Chemotherapy; Combination; Cancer; Nanocarriers; Drug delivery
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Drug Delivery Systems; Humans; Nanoparticles / administration & dosage; Nanoparticles / therapeutic use; Neoplasms / drug therapy
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine
BIOMATERIALS, 96, 1–10.
author keywords: Cancer; Protein delivery; DNA structures; Cytokine; Nanomedicine
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots
NANO LETTERS, 16(2), 1118–1126.
author keywords: Drug delivery; stimuli-responsive; tumor microenvironment; apoptosis; antiangiogenesis
MeSH headings : Angiogenesis Inhibitors / administration & dosage; Angiogenesis Inhibitors / chemistry; Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Apoptosis / drug effects; Breast Neoplasms / drug therapy; Breast Neoplasms / genetics; Cell Line, Tumor; Cell Membrane Permeability / drug effects; Drug Delivery Systems; Endosomes / drug effects; Gene Transfer Techniques; Humans; Hyaluronoglucosaminidase / biosynthesis; Hyaluronoglucosaminidase / chemistry; Mice; Snake Venoms / administration & dosage; Snake Venoms / chemistry; TNF-Related Apoptosis-Inducing Ligand / administration & dosage; Tumor Microenvironment / drug effects; Xenograft Model Antitumor Assays
Source: Web Of Science
Added: August 6, 2018
2015 journal article
ATP-responsive DNA-graphene hybrid nanoaggregates for anticancer drug delivery
BIOMATERIALS, 50, 67–74.
author keywords: ATP responsive; Graphene oxide; DNA; Drug delivery; Nanomedicine
MeSH headings : Adenosine Triphosphate / pharmacology; Antineoplastic Agents / pharmacology; Cell Death / drug effects; DNA, Single-Stranded / chemistry; Doxorubicin / pharmacology; Drug Delivery Systems; Endocytosis / drug effects; Graphite / chemistry; HeLa Cells; Humans; Intracellular Space / metabolism; Nanoparticles / chemistry; Particle Size; Spectrometry, Fluorescence
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Anticancer Platelet-Mimicking Nanovehicles
ADVANCED MATERIALS, 27(44), 7043-+.
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / metabolism; Antineoplastic Agents / pharmacology; Biomimetic Materials / chemistry; Blood Platelets / cytology; Cell Line, Tumor; Cell Membrane / chemistry; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Humans; Intracellular Space / metabolism; Mice; Nanomedicine / methods; Nanostructures / chemistry; TNF-Related Apoptosis-Inducing Ligand / chemistry; TNF-Related Apoptosis-Inducing Ligand / metabolism
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Characterization of a novel N-acetylneuraminic acid lyase favoring N-acetylneuraminic acid synthesis
SCIENTIFIC REPORTS, 5.
MeSH headings : Amino Acid Sequence; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Biocatalysis; Cloning, Molecular; Corynebacterium glutamicum / chemistry; Corynebacterium glutamicum / classification; Corynebacterium glutamicum / enzymology; Escherichia coli / enzymology; Escherichia coli / genetics; Gene Expression; Hexosamines / metabolism; Hydro-Lyases / chemistry; Hydro-Lyases / classification; Hydro-Lyases / genetics; Hydro-Lyases / metabolism; Kinetics; Molecular Sequence Data; N-Acetylneuraminic Acid / biosynthesis; Oxo-Acid-Lyases / chemistry; Oxo-Acid-Lyases / genetics; Oxo-Acid-Lyases / metabolism; Phylogeny; Pyruvic Acid / metabolism; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Sequence Alignment; Substrate Specificity
Source: Web Of Science
Added: August 6, 2018
2015 review
Engineering DNA scaffolds for delivery of anticancer therapeutics
[Review of ]. BIOMATERIALS SCIENCE, 3(7), 1018–1024.
MeSH headings : DNA / chemistry; Drug Carriers / chemistry; Drug Delivery Systems / methods; Engineering; Humans; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Nanoparticles / therapeutic use; Nanostructures / chemistry; Nanostructures / therapeutic use; Nanotechnology / methods; Neoplasms / chemistry; Neoplasms / drug therapy; Nucleic Acids / chemistry
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8260–8265.
author keywords: diabetes; drug delivery; glucose-responsive; hypoxia-sensitive; microneedle
MeSH headings : Animals; Blood Glucose / analysis; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Glucose / metabolism; Glucose Oxidase / metabolism; Humans; Hyaluronic Acid / chemistry; Hyaluronic Acid / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Hypoxia / metabolism; Insulin / administration & dosage; Insulin / chemistry; Insulin / metabolism; Male; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Molecular Structure; Oxidation-Reduction; Reproducibility of Results
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing
Angewandte Chemie International Edition, 54(41), 12029–12033.
author keywords: CRISPR-Cas9; DNA; drug delivery; genome editing; nanoparticles
MeSH headings : Animals; CRISPR-Associated Proteins / administration & dosage; CRISPR-Associated Proteins / chemistry; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems; Cell Line; Clustered Regularly Interspaced Short Palindromic Repeats; DNA / administration & dosage; DNA / chemistry; DNA / genetics; Green Fluorescent Proteins / genetics; Humans; Mice, Nude; Nanoparticles / chemistry; Neoplasms / genetics; Neoplasms / therapy; RNA, Guide, Kinetoplastida / administration & dosage; RNA, Guide, Kinetoplastida / chemistry; RNA, Guide, Kinetoplastida / genetics; Streptococcus pyogenes / chemistry; Streptococcus pyogenes / genetics
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Transformable liquid-metal nanomedicine
NATURE COMMUNICATIONS, 6(1).
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / chemistry; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers / chemistry; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Female; Gallium / chemistry; Humans; Indium / chemistry; Metal Nanoparticles / chemistry; Mice; Mice, Inbred BALB C; Nanomedicine / instrumentation; Nanomedicine / methods; Neoplasms / drug therapy
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Advances in Anticancer Protein Delivery using Micro-/Nanoparticles
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 31(12), 1204–1222.
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(42), 14722–14725.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; DNA / chemistry; DNA / metabolism; Deoxyribonucleases / metabolism; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Liberation; Humans; MCF-7 Cells; Models, Molecular; Molecular Conformation; Nanoparticles / chemistry
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Engineered cytidine triphosphate synthetase with reduced product inhibition
Protein Engineering Design & Selection, 27(7), 225–233.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery
CHEMICAL COMMUNICATIONS, 50(95), 15105–15108.
MeSH headings : Antineoplastic Agents / administration & dosage; Antineoplastic Agents / chemistry; Cell Survival / drug effects; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers / administration & dosage; Drug Carriers / chemistry; Folic Acid / administration & dosage; Folic Acid / chemistry; Glutathione / chemistry; HeLa Cells; Humans; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Oxidation-Reduction; Peptides / chemistry; Polyethylene Glycols / chemistry
Source: Web Of Science
Added: August 6, 2018
journal article
Furin-mediated sequential delivery of anticancer cytokine and small-molecule drug shuttled by graphene
Jiang, T. Y., Sun, W. J., Zhu, Q. W., Burns, N. A., Khan, S. A., Mo, R., & Gu, Z. Advanced Materials, 27(6), 1021–1028.
Source: NC State University Libraries
Added: August 6, 2018
