Wayne A Tompkins

Fozivudine Tidoxil as Single-Agent Therapy Decreases Plasma and Cell-Associated Viremia during Acute Feline Immunodeficiency Virus Infection

JOURNAL OF VETERINARY INTERNAL MEDICINE, 25(3), 413–418.

CD4(+)CD25(+) T Regulatory Cells Inhibit CD8(+) IFN-gamma Production During Acute and Chronic FIV Infection Utilizing a Membrane TGF-beta-Dependent Mechanism

AIDS RESEARCH AND HUMAN RETROVIRUSES, 26(2), 201–216.

CD4(+)CD25(+) T regulatory cells from FIV+ cats induce a unique anergic profile in CD8(+) lymphocyte targets

RETROVIROLOGY, 7.

CD4(+)CD25(+) regulatory T cells are infected and activated during acute FIV infection

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 126(3-4), 263–272.

Cloning of feline FOXP3 and detection of expression in CD4+CD25+ regulatory T cells

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 122(1-2), 159–166.

Lentivirus-induced immune dysregulation

Tompkins, M. B., & Tompkins, W. A. (2008, May 15). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, Vol. 123, pp. 45–55.

Transforming growth factor-beta/transforming growth factor-beta RII signaling may regulate CD4(+)CD25(+) T-regulatory cell homeostasis and suppressor function in feline AIDS lentivirus infection

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 47(2), 148–160.

Different thresholds of T cell activation regulate FIV infection of CD4(+)CD25(+) and CD4(+)CD25(-) cells

VIROLOGY, 335(2), 212–221.

Preferential feline immunodeficiency virus (FIV) infection of CD4(+) CD25(+) T-regulatory cells correlates both with surface expression of CXCR4 and activation of FIV long terminal repeat binding cellular transcriptional factors

JOURNAL OF VIROLOGY, 79(8), 4965–4976.

The role of CD4(+)CD25(+) regulatory T cells in viral infections

Vahlenkamp, T. W., Tompkins, M. B., & Tompkins, W. A. F. (2005, October 18). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, Vol. 108, pp. 219–225.

B7(+)CTLA4(+) T cells engage in T-T cell interactions that mediate apoptosis: a model for lentivirus-induced T cell depletion

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 98(3-4), 203–214.

Failure of FIV-infected cats to control Toxoplasma gondii correlates with reduced IL2, IL6, and IL12 and elevated IL10 expression by lymph node T cells

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 98(1-2), 101–111.

Feline immunodeficiency virus envelope glycoprotein mediates apoptosis in activated PBMC by a mechanism dependent on gp41 function

VIROLOGY, 330(2), 424–436.

Feline immunodeficiency virus infection phenotypically and functionally activates immunosuppressive CD4(+)CD25(+) T regulatory cells

JOURNAL OF IMMUNOLOGY, 172(8), 4752–4761.

Mechanism of feline immunodeficiency virus envelope glycoprotein-mediated fusion

VIROLOGY, 321(2), 274–286.

Preferential replication of FIV in activated CD4(+)CD25(+)T cells independent of cellular proliferation

VIROLOGY, 321(2), 307–322.

Spontaneous T cell apoptosis in feline immunodeficiency virus (FIV)-infected cats is inhibited by IL2 and anti-B7.1 antibodies

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 99(1-2), 25–37.

Evaluation of T lymphocytes in captive African lions (Panthera leo) infected with feline immunodeficiency virus

AMERICAN JOURNAL OF VETERINARY RESEARCH, 64(10), 1293–1300.

C-terminal gp40 peptide analogs inhibit feline immunodeficiency virus: Cell fusion and virus spread

JOURNAL OF VIROLOGY, 76(18), 9079–9086.

Evaluation of FIV protein-expressing VEE-replicon vaccine vectors in cats

VACCINE, 21(3-4), 258–268.

Feline immunodeficiency virus infection is characterized by B7(+)CTLA4(+) T cell apoptosis

Tompkins, M. B., Bull, M. E., Dow, J. L., Ball, J. M., Collisson, E. W., Winslow, B. J., … Tompkins, W. A. (2002, April 15). JOURNAL OF INFECTIOUS DISEASES, Vol. 185, pp. 1077–1093.

Infection of the choroid plexus by feline immunodeficiency virus

JOURNAL OF NEUROVIROLOGY, 8(3), 211–224.

Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro

JOURNAL OF VIROLOGY, 76(19), 9952–9961.

Polymorphic expression in the CD8 alpha chain surface receptor of African lions (Panthera leo)

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 84(3-4), 181–189.

B7.1/B7.2 and CTLA4 expression on feline T cells in vitro correlates with apoptosis

Journal of Leukocyte Biology, (2001), 255.

Constitutive expression of types 1 and 2 cytokines by alveolar macrophages from feline immunodeficiency virus-infected cats

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 79(1-2), 83–100.

Feline immunodeficiency virus (FIV) infection induces B7(+)CTLA4(+) T cell apoptosis: A model for T cell depletion and immunodeficiency

Journal of Leukocyte Biology, (2001), 254.

Nucleic acids obtained from the envelope coding region of feline immunodeficiency virus molecular clone designated JSY3

Washington, DC: U.S. Patent and Trademark Office.

T cell apoptosis in FIV-infected cats is blocked by the addition of antibodies to B7.1 and B7.2

Journal of Leukocyte Biology, (2001), 256.

Cloning and sequencing hybrid striped bass (Morone saxatilis x M. chrysops) transforming growth factor-β (TGF-β), and development of a reverse transcription quantitative competitive polymerase chain reaction (RT-qcPCR) assay to measure TGF-β mRNA of teleost fish

Fish & Shellfish Immunology, 10(1), 61–85.

T cells overexpressing interferon-gamma and interleukin-10 are found in both the thymus and secondary lymphoid tissues of feline immunodeficiency virus-infected cats

JOURNAL OF INFECTIOUS DISEASES, 181(2), 564–575.

Immunomodulation and therapeutic effects of the oral use of interferon-alpha: Mechanism of action

[Review of ]. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 19(8), 817–828.

Progressive expansion of an L-selectin-negative CD8 cell with anti-feline immunodeficiency virus (FIV) suppressor function in the circulation of FIV-infected cats

JOURNAL OF INFECTIOUS DISEASES, 180(5), 1503–1513.

Shedding of feline immunodeficiency virus in semen of domestic cats during acute infection

American Journal of Veterinary Research, 60(2), 211–215.

Biphasic thymus response by kittens inoculated with feline immunodeficiency virus during fetal development

VETERINARY PATHOLOGY, 35(3), 191–201.

Elevated interleukin-10-to-interleukin-12 ratio in feline immunodeficiency virus-infected cats predicts loss of type 1 immunity to Toxoplasma gondii

Levy, J. K., Ritchey, J. W., Rottman, J. B., Davidson, M. G., Liang, Y. H., Jordan, H. L., … Tompkins, M. B. (1998, August). JOURNAL OF INFECTIOUS DISEASES, Vol. 178, pp. 503–511.

Feline immunodeficiency virus is shed in semen from experimentally and naturally infected cats

AIDS RESEARCH AND HUMAN RETROVIRUSES, 14(12), 1087–1092.

Horizontal transmission of feline immunodeficiency virus with semen from seropositive cats

Journal of Reproductive Immunology, 41(1-2), 341–357.

Immunology of the cat: Nonspecific immunity in the cat

In Handbook of vertebrate immunology. San Diego: Academic Press.

Lessons from the cat: Feline immunodeficiency virus as a tool to develop intervention strategies against human immunodeficiency virus type 1

AIDS RESEARCH AND HUMAN RETROVIRUSES, 14(9), 797–801.

Mucosally transmitted feline immunodeficiency virus induces a CD8(+) antiviral response that correlates with reduction of cell-associated virus

Bucci, J. G., English, R. V., Jordan, H. L., Childers, T. A., Tompkins, M. B., & Tompkins, W. A. F. (1998, January). JOURNAL OF INFECTIOUS DISEASES, Vol. 177, pp. 18–25.

The CD8(+) cell phenotype mediating antiviral activity in feline immunodeficiency virus-infected cats is characterized by reduced surface expression of the CD8 beta chain

JOURNAL OF INFECTIOUS DISEASES, 178(4), 968–977.

Feline immunodeficiency virus isolate NCSU.sub.1

Washington, DC: U.S. Patent and Trademark Office.

Feline immunodeficiency virus isolate NCSU.sub.1Lb

Washington, DC: U.S. Patent and Trademark Office.