2014 journal article

Multiplexed miRNA detection using cationic polythiophene

ANALYTICAL METHODS, 6(7), 2399–2405.

By: W. Zheng n, T. Chase n & L. He n

TL;DR: The use of inherently encoded nanorods allowed simultaneous detection of different miRNA targets with good specificity and a detection limit of fmol amounts of miRNA was achieved, with a linear response spanning across a broad dynamic range. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Quantitative measurements of thermodynamics and kinetics of polythiophene-DNA complex formation in DNA detection

BIOMATERIALS SCIENCE, 2(10), 1471–1479.

By: W. Zheng n & L. He n

TL;DR: A systematic study to quantitatively measure the thermodynamic binding constants and hybridization rates of DNA duplexes in the presence/absence of cationic polythiophene and was able to improve the DNA sensing performance through a combined tuning of reaction temperature and time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Distance-Dependent Fluorescence Quenching or Conjugated Polymers on Au/kg Striped Nanorods

JOURNAL OF PHYSICAL CHEMISTRY C, 114(41), 17829–17835.

By: W. Zheng n & L. He n

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 article

Multiplexed detection of protein cancer markers on Au/Ag-barcoded nanorods using fluorescent-conjugated polymers

Zheng, W., & He, L. (2010, July). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 397, pp. 2261–2270.

By: W. Zheng n & L. He n

author keywords: Protein sensing; Multiplexing; Encoded nanoparticle; Solution array; Fluorescent-conjugated polymer; Cancer marker detection
MeSH headings : Animals; Biomarkers, Tumor / analysis; Cattle; Electronic Data Processing; Fluorescent Dyes; Gold; Humans; Immunoassay / methods; Limit of Detection; Nanotubes / chemistry; Neoplasm Proteins / analysis; Polymers; Sensitivity and Specificity; Silver
TL;DR: Integration of fluorescent-conjugated polymers as detection moiety with metallic striped nanorods for multiplexed detection of clinically important cancer marker proteins in an immunoassay format was demonstrated in this report. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Label-Free, Real-Time Multiplexed DNA Detection Using Fluorescent Conjugated Polymers

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(10), 3432-+.

By: W. Zheng n & L. He n

MeSH headings : Base Sequence; DNA / analysis; DNA Probes; Fluorescent Dyes / chemistry; Polymers / chemistry; Surface Plasmon Resonance
TL;DR: A label-free, multiplexed DNA assay using fluorescent conjugated polymers as a detection probe to illustrate hybridization on metallic striped nanorods shows attomole detection sensitivity and single-mutation specificity comparable to those of single-element assays but with much improved throughput. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Particle stability in polymer-assisted reverse colorimetric DNA assays

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 393(4), 1305–1313.

By: W. Zheng n & L. He n

author keywords: Metal divalent ions; DNA-functionalized gold nanoparticles; ATRP; Polymer-assisted reverse colorimetric method
MeSH headings : Colorimetry / methods; DNA / analysis; Kinetics; Metal Nanoparticles; Nucleic Acid Hybridization
TL;DR: The results show that Cu ions used as the polymerization catalyst bind strongly to the bases in DNA molecules, resulting in crosslinking of DNA-attached gold nanoparticles and their subsequent precipitation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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