Works (31)

Updated: July 21st, 2023 21:16

2022 journal article

Non-target and suspect-screening analyses of hydroponic soybeans and passive samplers exposed to different watershed irrigation sources

SCIENCE OF THE TOTAL ENVIRONMENT, 826.

By: S. Brecht, X. Kong n, D. Shea n, X. Xia n & E. Nichols n

author keywords: HRMS; Soybeans; Passive samplers; Wastewater; Hydroponics
MeSH headings : Agricultural Irrigation / methods; Hydroponics; Soybeans; Wastewater / analysis; Water / analysis; Water Pollutants, Chemical / analysis
Sources: Web Of Science, NC State University Libraries
Added: May 16, 2022

2020 journal article

Expanded coverage of non-targeted LC-HRMS using atmospheric pressure chemical ionization: a case study with ENTACT mixtures

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 412(20), 4931–4939.

author keywords: Atmospheric pressure chemical ionization (APCI); Non-targeted analysis (NTA); High-resolution mass spectrometry (HRMS); Electrospray ionization (ESI); EPA's Non-Targeted Analysis Collaborative Trial (ENTACT)
TL;DR: Examination of physicochemical parameters for ENTACT chemicals suggests that those with higher aqueous solubility preferentially ionized by ESI− suggest both APCI and ESI should be considered for broader coverage in future NTA research. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 22, 2020

2017 journal article

Effect of intra-articular administration of superparamagnetic iron oxide nanoparticles (SPIONs) for MRI assessment of the cartilage barrier in a large animal model

PLOS ONE, 12(12).

MeSH headings : Animals; Biomarkers / metabolism; Cartilage, Articular / diagnostic imaging; Cartilage, Articular / metabolism; Chemotaxis, Leukocyte; Coculture Techniques; Drug Administration Routes; Female; Fluorescent Dyes; Horses; Joints; Magnetic Resonance Imaging / methods; Magnetite Nanoparticles / administration & dosage; Male; Microscopy, Confocal; Models, Animal; Neutrophils / cytology; Swine
TL;DR: Results demonstrate an increase in MRI signal following conditioning of porcine joints which suggests that nanoparticle dependent compositional cartilage imaging is feasible, and could potentially lead to a new diagnostic technique for early detection of cartilage disease. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

LACK OF HYDROXYLATED FULLERENE TOXICITY AFTER INTRAVENOUS ADMINISTRATION TO FEMALE SPRAGUE-DAWLEY RATS

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 75(7), 367–373.

By: N. Monteiro-Riviere n, K. Linder n, A. Inman n, J. Saathoff n, X. Xia n & J. Riviere n

Contributors: N. Monteiro-Riviere n, K. Linder n, A. Inman n, J. Saathoff n, X. Xia n & J. Riviere n

MeSH headings : Animals; Blood Chemical Analysis; Drug Administration Schedule; Female; Fullerenes / administration & dosage; Fullerenes / chemistry; Fullerenes / toxicity; Injections, Intravenous; Liver / drug effects; Lymphocytes / drug effects; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Nanoparticles / toxicity; Rats; Rats, Sprague-Dawley; Thymus Gland / drug effects; Toxicity Tests, Acute; Urinalysis
TL;DR: These experiments suggest that this fullerol was well tolerated after iv administration to rats, and no clinically significant chemistry changes were observed after treatment. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells

TOXICOLOGY IN VITRO, 25(8), 2105–2112.

By: J. Saathoff n, A. Inman n, X. Xia n, J. Riviere n & N. Monteiro-Riviere n

Contributors: J. Saathoff n, A. Inman n, X. Xia n, J. Riviere n & N. Monteiro-Riviere n

author keywords: Hydroxylated fullerenes; Fullerenes; Cytotoxicity; Skin cells; Keratinocytes; Nanoparticles
MeSH headings : Biological Transport; Cell Survival; Cells, Cultured; Fullerenes / chemistry; Fullerenes / metabolism; Fullerenes / toxicity; Humans; Hydroxylation; Interleukin-8 / metabolism; Keratinocytes / drug effects; Keratinocytes / metabolism; Keratinocytes / ultrastructure; Microscopy, Electron, Transmission; Photoelectron Spectroscopy; Spectrometry, Fluorescence
TL;DR: Results suggest that different hydroxylation of fullerenes caused no cytotoxicity or inflammation up to 8.55 μg/ml, and suggest that extrapolation across similar NP will be dependent upon surface chemistry and concentration which may affect the degree of agglomeration and thus biological effects. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Mapping the Surface Adsorption Forces of Nanomaterials in Biological Systems

ACS NANO, 5(11), 9074–9081.

By: X. Xia n, N. Monteiro-Riviere n, S. Mathur*, X. Song*, L. Xiao*, S. Oldenberg*, B. Fadeel*, J. Riviere n

Contributors: X. Xia n, N. Monteiro-Riviere n, S. Mathur*, X. Song*, L. Xiao*, S. Oldenberg*, B. Fadeel*, J. Riviere n

author keywords: engineered nanomaterials; surface adsorption; risk assessment; nanotoxicology; nanomedicine; nanomaterial characterization
MeSH headings : Adsorption; Biology; Nanostructures / chemistry; Surface Properties
TL;DR: The BSAI nanodescriptors are intrinsic properties of nanomaterials useful for quantitative structure-activity relationship (QSAR) model development and could open a quantitative avenue in predictive nanomedicine development, risk assessment, and safety evaluation of nanmaterials. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

An index for characterization of nanomaterials in biological systems

Nature Nanotechnology, 5(9), 671–675.

By: X. Xia n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, N. Monteiro-Riviere n & J. Riviere n

MeSH headings : Adsorption; Hormones / chemistry; Models, Chemical; Nanostructures / chemistry; Nanotubes, Carbon / chemistry; Proteins / chemistry; Small Molecule Libraries / chemistry; Steroids / chemistry
TL;DR: The method successfully predicted the adsorption of various small molecules onto carbon nanotubes, and the nanodescriptors can be used to develop pharmacokinetic and safety assessment models for nanomaterials. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Intrinsic biological property of colloidal fullerene nanoparticles (nC(60)): Lack of lethality after high dose exposure to human epidermal and bacterial cells

TOXICOLOGY LETTERS, 197(2), 128–134.

By: X. Xia n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, N. Monteiro-Riviere n & J. Riviere n

author keywords: Water-soluble fullerenes; Nanotoxicity; Fullerene nanoparticles; Bacteria toxicity; Human epidermal keratinocytes
MeSH headings : Bacillus subtilis / drug effects; Epidermal Cells; Escherichia coli / drug effects; Fullerenes / chemistry; Fullerenes / toxicity; Humans; Keratinocytes / drug effects; Microbial Sensitivity Tests; Nanoparticles / chemistry; Nanoparticles / toxicity; Particle Size; Toxicity Tests
TL;DR: A novel method for preparing nC60 nanoparticles that does not use THF solvent, but provides nC 60 with an average particle size of 43.8 nm and a yield approximately 100 times higher than the THF method is reported, confirming the prior non-toxic reports when using nC50 prepared with non-THF methods. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Skin penetration and kinetics of pristine fullerenes (C-60) topically exposed in industrial organic solvents

TOXICOLOGY AND APPLIED PHARMACOLOGY, 242(1), 29–37.

By: X. Xia n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, N. Monteiro-Riviere n & J. Riviere n

author keywords: Dermal absorption; Stratum corneum; Nanomaterials; Fullerenes; Solvent effects; Nanotoxicity
MeSH headings : Algorithms; Animals; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Fullerenes / pharmacokinetics; Fullerenes / toxicity; Occupational Exposure / adverse effects; Particle Size; Skin / chemistry; Skin / pathology; Skin Absorption; Solvents / chemistry; Swine
TL;DR: The solvent effects on the stratum corneum absorption of C60 were consistent with those observed in vivo; in vitro flow-through diffusion cell experiments were conducted in pig skin and fullerenes were not detected in the receptor solutions by 24 h. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 article

A solvatochromatic approach to quantifying formulation effects on dermal permeability

SAR AND QSAR IN ENVIRONMENTAL RESEARCH, Vol. 19, pp. 615–630.

By: R. Baynes n, X. Xia n, V. Vijay n & J. Riviere n

author keywords: mixtures; skin; membrane-coated fiber; solvation energy
MeSH headings : Animals; Ethanol / metabolism; Models, Theoretical; Permeability / drug effects; Phenol / metabolism; Skin Physiological Phenomena; Solvents / metabolism; Swine; Toxicology / methods; Water / metabolism
TL;DR: This research demonstrated that formulation-specific strength coefficients predicted changes in the dermal permeability of phenolic compounds when formulated with commercial metal-working fluid formulations or 50% ethanol and that these effects can be modeled within the context of a linear solvation energy relationship (LSER). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Application of linear solvation energy relationships to a custom-made polyaniline solid-phase microextraction fiber and three commercial fibers

JOURNAL OF CHROMATOGRAPHY A, 1188(2), 108–117.

By: J. Yeatts n, R. Baynes n, X. Xia n & J. Riviere n

author keywords: polyaniline; solid-phase microextraction; biocides; linear solvation energy relationships; metal core fiber; partition coefficients
MeSH headings : Acrylic Resins / chemistry; Aniline Compounds / chemistry; Dimethylpolysiloxanes / chemistry; Disinfectants / chemistry; Microscopy, Electron, Scanning; Polyethylene Glycols / chemistry; Reproducibility of Results; Solid Phase Microextraction / methods; Thermodynamics
TL;DR: The LSER study showed that the system properties having the greatest influence on log K were ease of cavity formation and hydrogen bond donating ability, and showed that all four fibers offer a unique environment for solute partitioning. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Quantification of chemical mixture interactions modulating dermal absorption using a multiple membrane fiber array

CHEMICAL RESEARCH IN TOXICOLOGY, 21(3), 591–599.

By: R. Baynes n, X. Xia n, M. Irman & J. Riviere n

MeSH headings : Algorithms; Chemical Phenomena; Chemistry, Physical; Complex Mixtures / toxicity; Energy Transfer; Ethanol; Membranes, Artificial; Models, Biological; Regression Analysis; Skin Absorption / drug effects; Solvents
TL;DR: The utility of a three-membrane-coated fiber array to adequately predict changes in dermal permeability when skin is exposed to mixtures containing either a surfactant or a solvent is demonstrated and some insight is provided into the nature of the physiochemical interactions that modulate dermal absorptions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

A system coefficient approach for quantitative assessment of the solvent effects on membrane absorption from chemical mixtures

SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 18(5-6), 579–593.

By: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

author keywords: membrane absorption; chemical mixtures; solvent effects; system coefficient approach; solute descriptors
MeSH headings : Absorption; Dimethylpolysiloxanes / chemistry; Dimethylpolysiloxanes / metabolism; Kinetics; Membranes, Artificial; Models, Biological; Models, Chemical; Quantitative Structure-Activity Relationship; Regression Analysis; Silicones / chemistry; Silicones / metabolism; Solvents / chemistry
TL;DR: A system coefficient approach is proposed for quantitative assessment of the solvent effects on membrane absorption from chemical mixtures using Polydimethylsiloxane membrane-coated fibres and 32 probe compounds to demonstrate the proposed approach. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2007 journal article

An experimentally based approach for predicting skin permeability of chemicals and drugs using a membrane-coated fiber array

TOXICOLOGY AND APPLIED PHARMACOLOGY, 221(3), 320–328.

By: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

author keywords: skin permeability; predictive model; membrane-coated fiber; distribution coefficients; percutaneous absorption
MeSH headings : Algorithms; Complex Mixtures / chemistry; Complex Mixtures / pharmacokinetics; Forecasting; Humans; Membranes, Artificial; Models, Biological; Organic Chemicals / chemistry; Organic Chemicals / pharmacokinetics; Permeability; Pharmaceutical Preparations / chemistry; Pharmaceutical Preparations / metabolism; Reproducibility of Results; Skin / metabolism; Skin Absorption / drug effects; Structure-Activity Relationship
TL;DR: The MCF array approach is an experimentally based, high throughput approach that provides high prediction confidence and does not require literature data nor molecular structure information in contrast to the existing predictive models. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2007 journal article

Membrane-coated fiber array approach for predicting skin permeability of chemical mixtures from different vehicles

Toxicological Sciences, 99(1), 153–161.

By: J. Riviere n, R. Baynes n & X. Xia n

TL;DR: The results suggested that the experimentally based MCF array approach can be used to predict skin absorption from chemical mixtures in different vehicles or formulations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2007 journal article

Partitioning behavior of aromatic components in jet fuel into diverse membrane-coated fibers

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 70(22), 1879–1887.

By: R. Baynes n, X. Xia n, B. Barlow n & J. Riviere n

MeSH headings : 1-Octanol / chemistry; Acrylic Resins / chemistry; Culture Media / chemistry; Dimethylpolysiloxanes / chemistry; Ethanol / chemistry; Humans; Hydrocarbons, Aromatic / chemistry; Hydrocarbons, Aromatic / metabolism; Membranes, Artificial; Models, Biological; Polyethylene Glycols / chemistry; Skin Absorption; Water / chemistry
TL;DR: It is demonstrated that a single or multiple set of MCF fibers may be used as a surrogate for octanol/water systems and skin to assess partitioning behavior of nine aromatic components frequently formulated with jet fuels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 report

Quantitating the absorption, partitioning and toxicity of hydrocarbon components of JP-8 jet fuel

(Center for Chemical Toxicology Research and Pharmacokinetics Grant No. FA9550-04-1-0376).

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Regression method of the hydrophobicity for determining octanol/water partition ruler approach coefficients of very hydrophobic compounds

CHEMOSPHERE, 66(6), 1086–1093.

By: X. Kong n, D. Shea n, R. Baynes n, J. Riviere n & X. Xia n

Contributors: X. Kong n, D. Shea n, R. Baynes n, J. Riviere n & X. Xia n

author keywords: octanol/water partition coefficient; hydrophobic compound; indirect method; regression method; hydrophobicity
MeSH headings : Calibration; Dimethylpolysiloxanes; Hydrophobic and Hydrophilic Interactions; Kinetics; Methanol; Models, Chemical; Octanols; Polychlorinated Biphenyls / chemistry; Regression Analysis; Silicones; Water
TL;DR: A regression method was developed for the hydrophobicity ruler approach, which is an indirect method for determining the octanol/water partition coefficients of very hydrophobic compounds by regression of the absorption data sampled before the partition equilibrium. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 journal article

Trace analysis of fullerenes in biological samples by simplified liquid-liquid extraction and high-performance liquid chromatography

JOURNAL OF CHROMATOGRAPHY A, 1129(2), 216–222.

By: X. Xia n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, N. Monteiro-Riviere n & J. Riviere n

author keywords: fullerenes; nanoparticles; colloidal nanoparticles; emulsion; liquid-liquid extraction; solvent evaporation; dermal absorption
MeSH headings : Chromatography, High Pressure Liquid / methods; Emulsions / chemistry; Fullerenes / analysis; Fullerenes / chemistry; Nanoparticles / chemistry; Reproducibility of Results; Solvents / chemistry
TL;DR: A simplified LLE method was developed for high throughput while preserved the advantages of the traditional LLE and was used for trace analysis of fullerenes in protein containing media and tape-stripped skin samples. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 journal article

Membrane uptake kinetics of jet fuel aromatic hydrocarbons from aqueous solutions studied by a membrane-coated fiber technique

TOXICOLOGY MECHANISMS AND METHODS, 15(4), 307–316.

By: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

author keywords: uptake kinetics; membrane-coated fiber; partition coefficient; jet fuel; aromatic hydrocarbons
TL;DR: The results suggest that the MCF technique can detect subtle differences in molecular interactions of the two group derivatives between the two membrane/water systems and may be used to study the absorption and permeation properties of closely related compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 journal article

Novel hydrophobicity ruler approach for determining the octanol/water partition coefficients of very hydrophobic compounds via their polymer/solvent solution distribution coefficients

ANALYTICAL CHEMISTRY, 77(5), 1275–1281.

By: X. Kong n, D. Shea n, W. Gebreyes n & X. Xia n

Contributors: X. Kong n, D. Shea n, W. Gebreyes n & X. Xia n

MeSH headings : Acetone / chemistry; Adsorption; Dimethylpolysiloxanes / chemistry; Gas Chromatography-Mass Spectrometry; Hydrophobic and Hydrophilic Interactions; Kinetics; Methanol / chemistry; Octanols / chemistry; Organic Chemicals / chemistry; Polychlorinated Biphenyls / chemistry; Polymers / chemistry; Reproducibility of Results; Silicones / chemistry; Solvents / chemistry; Water / chemistry
TL;DR: A novel hydrophobicity ruler approach for determining the octanol/water partition coefficients of very hydrophobic compounds is proposed, which is an indirect method that measures the polymer/solvent solution distribution coefficients (log Kp/s) of reference and unknown compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2004 journal article

A Compartment Model for the Membrane-Coated Fiber Technique Used for Determining the Absorption Parameters of Chemicals into Lipophilic Membranes

Pharmaceutical Research, 21(8), 1345–1352.

By: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

author keywords: absorption kinetics; lipophilic membrane; membrane-coated fiber; partition coefficient; uptake rate constant
MeSH headings : Absorption; Gas Chromatography-Mass Spectrometry / methods; Kinetics; Membranes, Artificial; Models, Biological; Permeability; Pesticides / analysis; Pesticides / chemistry; Reproducibility of Results; Solubility
TL;DR: A compartment model for the membrane-coated fiber (MCF) technique for determining the absorption parameters of chemicals into lipophilic membranes can describe the absorption kinetics of the MCF technique and is a useful tool for the determination of the partition coefficients of Lipophilic compounds when it takes too long for them to reach permeation equilibrium. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

Characterization of polyacrylate membrane-coated fibers used in chemical absorption studies with programmed thermal treatment and FT-IR microscopy

ANALYTICAL CHEMISTRY, 76(14), 4245–4250.

By: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

TL;DR: The anhydride formation explained the absorption property of PA MCFs in GC applications where they must be preconditioned at 300 degrees C and suggested that a PA fiber does not preferably absorb polar compounds (with permanent dipole moment); instead, it absorbs preferably aromatic compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2004 journal article

Determination of the partition coefficients and absorption kinetic parameters of chemicals in a lipophilic membrane/water system by using a membrane-coated fiber technique

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 24(1), 15–23.

By: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

Contributors: X. Xia n, R. Baynes n, N. Monteiro-Riviere n & J. Riviere n

author keywords: absorption kinetics; membrane-coated fiber; diffusion coefficient; partition coefficient; boundary layer
MeSH headings : Absorption / drug effects; Absorption / physiology; Kinetics; Lipid Metabolism; Membranes, Artificial; Organic Chemicals / pharmacokinetics; Water / metabolism
TL;DR: The kinetic model adequately described the absorption kinetics of the MCF technique and suggested that the absorption rate of a very lipophilic compound could be controlled by the boundary layer even though the diffusivity of the compound in the membrane is lower than that in the solution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2004 journal article

Dose related absorption of JP-8 jet fuel hydrocarbons through porcine skin with quantitative structure permeability relationship analysis

TOXICOLOGY MECHANISMS AND METHODS, 14(3), 159–166.

By: F. Muhammad n, R. Baynes n, N. Monteiro-Riviere n, X. Xia n & J. Riviere n

Contributors: F. Muhammad n, R. Baynes n, N. Monteiro-Riviere n, X. Xia n & J. Riviere n

author keywords: absorption; GC-SPME; hydrocarbons; jet fuels; porcine skin; QSPR
TL;DR: The findings suggested a dose related increase in absorption for naphthalene and dimethyl naphthaene (DMN) in this solvent system by using their physicochemical parameters. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2003 journal article

A novel in-vitro technique for studying percutaneous permeation with a membrane-coated fiber and gas chromatography/mass spectrometry: Part I. Performances of the technique and determination of the permeation rates and partition coefficients of chemical mixtures

PHARMACEUTICAL RESEARCH, 20(2), 275–282.

By: X. Xia n, R. Baynes*, N. Monteiro-Riviere*, R. Leidy*, D. Shea* & J. Riviere*

Contributors: X. Xia n, R. Baynes*, N. Monteiro-Riviere*, R. Leidy*, D. Shea* & J. Riviere*

author keywords: in-vitro; percutaneous absorption; membrane-coated fiber; chemical mixtures; partition coefficient
MeSH headings : Administration, Cutaneous; Gas Chromatography-Mass Spectrometry / instrumentation; Gas Chromatography-Mass Spectrometry / methods; Membranes, Artificial; Permeability; Pharmaceutical Preparations / analysis; Pharmaceutical Preparations / metabolism
TL;DR: A novel in-vitro technique for rapid assessment of percutaneous absorption of chemical mixtures and the initial permeation rate and equilibrium time can be obtained for each compound, which could serve as characteristic parameters regarding the skin permeability of the compound. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2002 journal article

A simplified liquid-solid extraction technique for the analyses of pesticide residues in soil samples

ENVIRONMENTAL MONITORING AND ASSESSMENT, 73(2), 179–190.

By: X. Xia n & R. Leidy n

author keywords: equilibrium; GC-ECD; liquid-solid extraction; organochlorine pesticides; soils; surface adsorption
MeSH headings : Adsorption; Chromatography, Gas; Environmental Monitoring / methods; Pesticide Residues / analysis; Reference Values; Sensitivity and Specificity; Soil Pollutants / analysis; Specimen Handling
TL;DR: A simplified liquid-solid extraction technique was studied for the analyses of pesticide residues in soil samples and linear response curves were obtained for all of the target compounds regardless of their surface adsorption. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Preparation and characterization of porous silica coated multifibers for solid-phase microextraction

ANALYTICAL CHEMISTRY, 73(9), 2041–2047.

By: X. Xia n & R. Leidy n

MeSH headings : Chromatography, Gas; Filtration / methods; Gas Chromatography-Mass Spectrometry / instrumentation; Gas Chromatography-Mass Spectrometry / methods; Hydrocarbons, Chlorinated; Insecticides / analysis; Microscopy, Electron, Scanning; Pesticide Residues / analysis; Silicon Dioxide / chemistry; Water / analysis
TL;DR: The porous multifiber SPME provided larger absorption capacity and higher absorption rate compared to a polymer-coated single fiber and its high extraction efficiency enabled the positive identification of unknown compounds at sub-part-per-billion level in full-scan mode with a benchtop quadruple GC/MS. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

chapter

A novel system coefficient approach for systematic assessment of dermal absorption from chemical mixtures

Xia, X. R., Baynes, R. E., & Riviere, J. E. In Dermal absorption models in toxicology and pharmacology (pp. 69–86). New York: Taylor and Francis / CRC Press.

By: X. Xia, R. Baynes & J. Riviere

Source: NC State University Libraries
Added: August 6, 2018

patent

Method and apparatus for determining a molecular descriptor of absorption for a candidate compound

Riviere, J. E., Xia, X. R., Baynes, R. E., & Monteiro-Riviere, N. A.

Source: NC State University Libraries
Added: August 6, 2018

report

Quantitating the percutaneous absorption of mechanistically-defined chemical mixtures

Riviere, J. E., Montiero-Riviere, N. A., Baynes, R. E., Xia, X. R., & Smith, C. E. (Vol. 34, p. 1).

By: J. Riviere, N. Montiero-Riviere, R. Baynes, X. Xia & C. Smith

Source: NC State University Libraries
Added: August 6, 2018

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