@article{zhao_pike_huang_feng_odle_lin_2023, title={Effects of medium chain triglycerides on hepatic fatty acid oxidation in clofibrate-fed newborn piglets}, volume={12}, ISSN={["2405-6545"]}, url={https://doi.org/10.1016/j.aninu.2022.12.001}, DOI={10.1016/j.aninu.2022.12.001}, journal={ANIMAL NUTRITION}, author={Zhao, Jinan and Pike, Brandon and Huang, Jin and Feng, Zhihua and Odle, Jack and Lin, Xi}, year={2023}, month={Mar}, pages={334–344} } @article{pike_zhao_hicks_wang_hagen_liu_odle_2023, title={Intestinal Carnitine Status and Fatty Acid Oxidation in Response to Clofibrate and Medium-Chain Triglyceride Supplementation in Newborn Pigs}, url={https://doi.org/10.3390/ijms24076066}, DOI={10.3390/ijms24076066}, journal={International Journal of Molecular Sciences}, author={Pike, Brandon and Zhao, Jinan and Hicks, Julie A. and Wang, Feng and Hagen, Rachel and Liu, Hsiao-Ching and Odle, Jack}, year={2023}, month={Mar} } @article{qin_huang_lu_zhang_guo_xi_liao_luo_2023, title={Manganese alleviates heat stress of primary cultured chick embryonic myocardial cells via enhancing manganese superoxide dismutase expression and attenuating heat shock response}, volume={112}, ISSN={["1879-0992"]}, DOI={10.1016/j.jtherbio.2022.103440}, journal={JOURNAL OF THERMAL BIOLOGY}, author={Qin, Shizhen and Huang, Liang and Lu, Lin and Zhang, Liyang and Guo, Yanli and Xi, Lin and Liao, Xiudong and Luo, Xugang}, year={2023}, month={Feb} } @article{boston_wang_lin_leonard_kim_mckilligan_fellner_odle_2022, title={Gruel Creep Feeding Accelerates Growth and Alters Intestinal Health of Young Pigs}, volume={12}, ISSN={["2076-2615"]}, url={https://www.mdpi.com/2076-2615/12/18/2408}, DOI={10.3390/ani12182408}, number={18}, journal={ANIMALS}, author={Boston, Timothy E. and Wang, Feng and Lin, Xi and Leonard, Suzanne and Kim, Sung Woo and McKilligan, Denny and Fellner, Vivek and Odle, Jack}, year={2022}, month={Sep} } @article{shipman_xi_van heugten_2022, title={Reproductive Performance, Early Embryo Survival, Fetal Characteristics, and Tissue Fatty Acid Profiles of Sows Fed Linoleic or alpha-Linolenic Acid}, volume={100}, journal={Journal of Animal Science}, author={Shipman, G. and Xi, L. and van Heugten, E.}, year={2022}, pages={55} } @article{chang_mcnulty_hibberd_o’donnell_cheng_lombard_henrissat_ilkayeva_muehlbauer_newgard_et al._2021, title={Gut microbiome contributions to altered metabolism in a pig model of undernutrition}, volume={118}, ISSN={0027-8424 1091-6490}, url={http://dx.doi.org/10.1073/pnas.2024446118}, DOI={10.1073/pnas.2024446118}, abstractNote={The concept that gut microbiome-expressed functions regulate ponderal growth has important implications for infant and child health, as well as animal health. Using an intergenerational pig model of diet restriction (DR) that produces reduced weight gain, we developed a feature-selection algorithm to identify representative characteristics distinguishing DR fecal microbiomes from those of full-fed (FF) pigs as both groups consumed a common sequence of diets during their growth cycle. Gnotobiotic mice were then colonized with DR and FF microbiomes and subjected to controlled feeding with a pig diet. DR microbiomes have reduced representation of genes that degrade dominant components of late growth-phase diets, exhibit reduced production of butyrate, a key host-accessible energy source, and are causally linked to reduced hepatic fatty acid metabolism (β-oxidation) and the selection of alternative energy substrates. The approach described could aid in the development of guidelines for microbiome stewardship in diverse species, including farm animals, in order to support their healthy growth.}, number={21}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Chang, Hao-Wei and McNulty, Nathan P. and Hibberd, Matthew C. and O’Donnell, David and Cheng, Jiye and Lombard, Vincent and Henrissat, Bernard and Ilkayeva, Olga and Muehlbauer, Michael J. and Newgard, Christopher B. and et al.}, year={2021}, month={May}, pages={e2024446118} } @article{pike_hicks_zhao_liu_odle_xi_2021, title={Maternal Supplementation of Clofibrate Stimulates Intestinal Fatty Acid Oxidation in Newborn Suckling Piglets}, volume={5}, ISSN={2475-2991}, url={http://dx.doi.org/10.1093/cdn/nzab042_009}, DOI={10.1093/cdn/nzab042_009}, abstractNote={Abstract Objectives To evaluate the effects of maternal feeding of clofibrate, a pharmaceutical PPARα agonist, on the development of intestinal fatty acid metabolism in offspring using the pig as a model. Methods A total of 27 pregnant sows were randomly assigned into three treatment groups. Each group was fed a standard diet (3265 kcal ME/kg) supplemented with either 0, 0.25% or 0.5% clofibrate (w/w) from d 107 of gestation to d 7 of lactation. A piglet from each litter was sampled on 1, 7, 14 and 19 d of age. Fatty acid oxidation was examined in homogenates of ileum mucosa using 1 mM [1–14C] oleic acid as a substrate in the absence or presence of in vitro supplemented L-carnitine (1 mM), malonate (10 mM) or carnitine + malonate. Results The metabolism of [1–14C] oleic acid was modified by the maternal clofibrate, and the effects varied with the dose of clofibrate and postnatal age (p < 0.001). The 14C accumulation in 14CO2 increased by 2.4 fold at d7 (vs d1), but showed no difference after d7. Maternal clofibrate stimulated the 14CO2 accumulation from d1 to d19, but the stimulation decreased with postnatal age. The 14C accumulation in acid soluble products (14C-ASP) was reduced by 8.4 fold at d7 (vs d1), and no difference was observed after d7. Maternal clofibrate increased 14C-ASP at d1, and the effect was greater as maternal clofibrate was incremented from 0.25 to 0.5%. The 14C accumulation in esterified products (14C-ESP) was greater at d7 than d1, 14 and 19. Maternal clofibrate reduced the 14C-ESP and, again the reduction was stronger with increasing clofibrate dose. In vitro supplementation of carnitine increased 14CO2 by 60% and 14C-ASP by 120%, but reduced 14C-ESP by 39% compared to control incubations. Supplementation of malonate reduced 14CO2 by 95% and 14C-ESP by 44%, but no effect on 14C-ASP was detected. Conclusions Maternal dietary supplementation of clofibrate increases intestinal fatty acid oxidation in suckling offspring, but the increase is attenuated after one week. Inhibition of the TCA cycle reduces CO2 production without affecting ASP. The availability of carnitine could be a key element to maintain a high rate of intestinal fatty acid oxidation during the neonatal period. Funding Sources Supported by Program of Animal Nutrition, Growth and Lactation [grant no. 2015–67015-23245/project accession no. 1005855] from the USDA NIFA. }, number={Supplement_2}, journal={Current Developments in Nutrition}, publisher={Oxford University Press (OUP)}, author={Pike, Brandon and Hicks, Julie and Zhao, Jinan and Liu, Hsiao-Ching and Odle, Jack and Xi, Lin}, year={2021}, month={Jun}, pages={542–542} } @article{wang_maltecca_wang_odle_xi_2021, title={MicroRNA and mRNA Sequencing Analyses Reveal Key Hepatic Metabolic Pathways Responsive to Maternal Malnutrition in Full-Term Fetal Pigs}, volume={5}, ISSN={2475-2991}, url={http://dx.doi.org/10.1093/cdn/nzab046_126}, DOI={10.1093/cdn/nzab046_126}, abstractNote={Abstract Objectives Maternal and infant undernutrition is highly prevalent in developing countries, leading to serious fetus/infant mortality, intrauterine growth restriction, stunting, and severe wasting. However, the effects of maternal undernutrition have generally focused on the reduced maternal nutrient supply to the fetus. The potential impairment of fetal metabolic pathways has not been well studied. Methods Pregnant gilts (Landrace x Yorkshire x Duroc) received the NRC gestation diet with (n = 4) or without (n = 4) 50% intake restriction at insemination day and 70% for the following gestation period. Full term fetuses were obtained via C-section, two piglets were selected from each gilt in both groups and subject to hepatic tissue collection. MicroRNA and mRNA deep sequencing analysis was performed using the Illumina GAIIx system. The mRNA-miRNA correlation and associated signaling pathways were analyzed via CLC workbench, Ingenuity Pathway Analysis Software. Results A total of 42 differentially expressed miRNAs were identified between intake-restriction and full-nutrition group. Among of these, mir-206, mir-133b, mir-1246, mir-1843 and mir-7139 are the most downregulated and mir-10b, mir-708 and mir-222 are the most upregulated miRNAs. A total of 1215 mRNAs were identified to differentially expressed between two groups. Two metabolic pathways: retinol biosynthesis and oxidative phosphorylation were significantly modified, and the modification was associated with the miRNA changes induced by the maternal feed restriction. Briefly, the retinol biosynthesis pathway was upregulated (p < 0.01), in which those differential expressed mir-221, mir-4492, mir-1281 and mir-4492 were predicted targeting genes AADAC, CES3, PNPLA3 and RDH13 in the pathway. The oxidative phosphorylation pathway was upregulated (p < 0.05), and those differential expressed mir-1843, mir-222 and mir-184 were predicted targeting genes ATP5F1C, NDUFA1, NDUFB10, and NDUFS7 in this pathway. Conclusions These results provide the framework for further understanding of negative impact of maternal malnutrition on hepatic metabolic pathways via miRNA-RNA interactions in full-term fetal pigs. Funding Sources Supported in part by the Bill and Melinda Gates Foundation (GCE OPP1061037) and by the North Carolina Agricultural Research Service. }, number={Supplement_2}, journal={Current Developments in Nutrition}, publisher={Oxford University Press (OUP)}, author={Wang, Feng and Maltecca, Christian and Wang, Xiaoqiu and Odle, Jack and Xi, Lin}, year={2021}, month={Jun}, pages={829–829} } @article{wang_li_odle_lin_zhao_xiao_liu_2021, title={Modulation of intestinal stem cell homeostasis by nutrients: a novel therapeutic option for intestinal diseases}, volume={6}, ISSN={0954-4224 1475-2700}, url={http://dx.doi.org/10.1017/S0954422421000172}, DOI={10.1017/S0954422421000172}, abstractNote={Abstract Intestinal stem cells, which are capable of both self-renewal and differentiation to mature cell types, are responsible for maintaining intestinal epithelial homeostasis. Recent evidence indicates that these processes are mediated, in part, through nutritional status in response to diet. Diverse dietary patterns including caloric restriction, fasting, high-fat diets, ketogenic diets and high-carbohydrate diets as well as other nutrients control intestinal stem cell self-renewal and differentiation through nutrient-sensing pathways such as mammalian target of rapamycin and AMP-activated kinase. Herein, we summarise the current understanding of how intestinal stem cells contribute to intestinal epithelial homeostasis and diseases. We also discuss the effects of diet and nutrient-sensing pathways on intestinal stem cell self-renewal and differentiation, as well as their potential application in the prevention and treatment of intestinal diseases.}, journal={Nutrition Research Reviews}, publisher={Cambridge University Press (CUP)}, author={Wang, Dan and Li, Pei and Odle, Jack and Lin, Xi and Zhao, Jiangchao and Xiao, Kan and Liu, Yulan}, year={2021}, month={Jun}, pages={1–9} } @article{li_he_liao_lin_zhang_lu_guo_liu_luo_2021, title={Zinc alleviates the heat stress of primary cultured hepatocytes of broiler embryos via enhancing the antioxidant ability and attenuating the heat shock responses}, volume={7}, ISSN={2405-6545}, url={http://dx.doi.org/10.1016/j.aninu.2021.01.003}, DOI={10.1016/j.aninu.2021.01.003}, number={3}, journal={Animal Nutrition}, publisher={Elsevier BV}, author={Li, Tingting and He, Wengang and Liao, Xiudong and Lin, Xi and Zhang, Liyang and Lu, Lin and Guo, Yanli and Liu, Zongping and Luo, Xugang}, year={2021}, month={Sep}, pages={621–630} } @article{lin_pike_zhao_fan_zhu_zhang_wang_odle_2020, title={Effects of Dietary Anaplerotic and Ketogenic Energy Sources on Renal Fatty Acid Oxidation Induced by Clofibrate in Suckling Neonatal Pigs}, volume={21}, ISSN={1422-0067}, url={http://dx.doi.org/10.3390/ijms21030726}, DOI={10.3390/ijms21030726}, abstractNote={Maintaining an active fatty acid metabolism is important for renal growth, development, and health. We evaluated the effects of anaplerotic and ketogenic energy sources on fatty acid oxidation during stimulation with clofibrate, a pharmacologic peroxisome proliferator-activated receptor α (PPARα) agonist. Suckling newborn pigs (n = 72) were assigned into 8 dietary treatments following a 2 × 4 factorial design: ± clofibrate (0.35%) and diets containing 5% of either (1) glycerol-succinate (GlySuc), (2) tri-valerate (TriC5), (3) tri-hexanoate (TriC6), or (4) tri-2-methylpentanoate (Tri2MPA). Pigs were housed individually and fed the iso-caloric milk replacer diets for 5 d. Renal fatty acid oxidation was measured in vitro in fresh tissue homogenates using [1-14C]-labeled palmitic acid. The oxidation was 30% greater in pig received clofibrate and 25% greater (p < 0.05) in pigs fed the TriC6 diet compared to those fed diets with GlySuc, TriC5, and Tri2MPA. Addition of carnitine also stimulated the oxidation by twofold (p < 0.05). The effects of TriC6 and carnitine on palmitic acid oxidation were not altered by clofibrate stimulation. However, renal fatty acid composition was altered by clofibrate and Tri2MPA. In conclusion, modification of anaplerosis or ketogenesis via dietary substrates had no influence on in vitro renal palmitic acid oxidation induced by PPARα activation.}, number={3}, journal={International Journal of Molecular Sciences}, publisher={MDPI AG}, author={Lin, Xi and Pike, Brandon and Zhao, Jinan and Fan, Yu and Zhu, Yongwen and Zhang, Yong and Wang, Feng and Odle, Jack}, year={2020}, month={Jan}, pages={726} } @article{keerthisinghe_wang_wang_yang_li_yang_xi_dong_fang_2020, title={Long-term exposure to TET increases body weight of juvenile zebrafish as indicated in host metabolism and gut microbiome}, volume={139}, ISSN={0160-4120}, url={http://dx.doi.org/10.1016/j.envint.2020.105705}, DOI={10.1016/j.envint.2020.105705}, journal={Environment International}, publisher={Elsevier BV}, author={Keerthisinghe, Tharushi Prabha and Wang, Feng and Wang, Mengjing and Yang, Qin and Li, Jiawei and Yang, Jingfeng and Xi, Lin and Dong, Wu and Fang, Mingliang}, year={2020}, month={Jun}, pages={105705} } @article{xi_pike_zhao_odle_2020, title={Maternal Feeding of a Synthetic PPARα Agonist Alters Renal Development of Fatty Acid Metabolism in the Neonatal Piglet}, volume={4}, ISSN={2475-2991}, url={http://dx.doi.org/10.1093/cdn/nzaa050_025}, DOI={10.1093/cdn/nzaa050_025}, abstractNote={Abstract Objectives Clofibrate as a therapeutic agent has been used for controlling hyperlipidemias of humans for more than 50 years. Its action, metabolism, half-life and excretion have been well documented in liver of adult humans and rodent species, but it has not been evaluated well in extrahepatic tissues in neonates as a stimulator of energy utilization. In this study, the role of maternal administration of clofibrate in development of renal fatty acid oxidation was evaluated using swine as a model. Methods A randomized complete block design was used with a total of 27 pregnant sows. The sows were fed standard gestation-lactation diets supplemented with either 0 (control), 0.25% or 0.5% clofibrate (w/w) from d 107 of gestation to d 7 of lactation. Fatty acid oxidation was measured in the presence or absence of carnitine (1 mM) or/and malonate (5 mM) in fresh kidney homogenates from piglets at d1, 7, 14 and 19 of age using 14C-oleic acid (1 mM) as substrate (9.9 mBq/mmol). Results Interactions (P < 0.001) were observed between maternal clofibrate levels and postnatal age on 14C accumulation in CO2 (14CO2), acid soluble products (14C-ASP) and esterified products (14C-ESP). The 14CO2 increased by 1.3 fold from d1 to d7, but showed no differences between d7, 14 and 19 in pigs from the control sows. Maternal supplementation of clofibrate increased 14CO2 in pigs across all ages, but the increase was higher in pigs from sows fed 0.5% versus 0.25% clofibrate at d14. The 14C-ASP was 7-fold higher in d1 pigs from control sows than all other ages. Maternal supplementation of clofibrate increased 14C-ASP by 2 fold in pigs at d1, but had no detectable effect at d 7, 14 and 19. The 14C-ESP increased from d1 to d7 and decreased from d7 to d19 in pigs from control sows. Maternal supplementation of clofibrate had no detectable impact on 14C-ESP at d1, 14 and 19, but decreased 14C-ESP measured in d7 pigs. In vitro carnitine supplementation increased 14CO2 and malonate supplementation decreased 14CO2, but neither carnitine nor malonate altered 14C-ASP or 14C-ESP. Conclusions The stimulatory effect of maternal clofibrate on renal fatty acid metabolism in offspring is associated with the postnatal age, being greater at d1 and d7 than d14 and d19. Funding Sources USDA National Institute of Food and Agriculture. }, number={Supplement_2}, journal={Current Developments in Nutrition}, publisher={Oxford University Press (OUP)}, author={Xi, Lin and Pike, Brandon and Zhao, Jinan and Odle, Jack}, year={2020}, month={May}, pages={702–702} } @article{zhao_pike_odle_xi_2020, title={Maternal Supplementation of Clofibrate Stimulates Hepatic Fatty Acid Oxidation in Newborn Suckling Piglets}, volume={4}, ISSN={2475-2991}, url={http://dx.doi.org/10.1093/cdn/nzaa050_026}, DOI={10.1093/cdn/nzaa050_026}, abstractNote={Abstract Objectives To evaluate effects of maternal feeding of clofibrate, a PPARα agonist, on development of hepatic fatty acid metabolism in offspring using pig as a model. Methods Pregnant sows (N = 27) were randomly assigned into three treatment groups. Each group was fed a standard diet (3265 kcal ME/kg) supplemented with either 0, 0.25% or 5% clofibrate (w/w) from d 107 of gestation to d 7 of lactation. Liver tissue was collected from piglets at birth, d1, 7, 14 and 19. Fatty acid oxidation was examined in fresh homogenates using 1 mM [1–14C] oleic acid (9.9 mBq/mmol) as substrate. Oxidation was measured in the absence or presence of in vitro supplemented L-carnitine (1 mM) and/or malonate (5 mM). Results Clofibrate was not detected in piglet liver or sow milk. Interactions between clofibrate and postnatal age (P < 0.001) on the 14C accumulation in 14CO2, acid soluble products (14C-ASP) and esterified products (14C-ESP) were observed. Accumulation in 14CO2 was not altered by piglet age in control sows; however, accumulation in 14C-ASP was higher at d14 and lower at d19 compared to d1. In contrast, maternal clofibrate increased 14CO2 by 100% and 14C-ASP by 80% in pigs at d1, and the increase was higher in pigs from sows given 0.5% versus 0.25% clofibrate. Accumulation in 14C-ESP in pigs from control sows increased from d1 to d14, but there was no difference detected between d14 and 19. Assessment of pigs from sows fed the 0.25% clofibrate dose revealed no impact on 14C-ESP, but the 0.5% dose increased 14C-ESP by 31%. No interaction was observed between clofibrate and the in vitro treatments (carnitine and malonate; P = 0.5). In vitro supplementation of carnitine increased radiolabel accumulation in CO2 by 60% and in ASP by 120%, but reduced 14C-ESP by 39% compared to control incubations. Supplementation of malonate reduced 14CO2 by 95% and 14C-ESP by 44%, but had no impact on 14C-ASP. Conclusions Maternal clofibrate enhances hepatic fatty acid metabolism in offspring, but the effect fades with postpartum age. The availability of carnitine in the milk could be a key element to support fatty acid oxidation in postnatal pigs. Funding Sources USDA National Institute of Food and Agriculture. }, number={Supplement_2}, journal={Current Developments in Nutrition}, publisher={Oxford University Press (OUP)}, author={Zhao, Jinan and Pike, Brandon and Odle, Jack and Xi, Lin}, year={2020}, month={May}, pages={703–703} } @article{lin_lyvers peffer_woodworth_odle_2020, title={Ontogeny of carnitine biosynthesis inSus scrofa domesticus, inferred from γ-butyrobetaine hydroxylase (dioxygenase) activity and substrate inhibition}, volume={319}, ISSN={0363-6119 1522-1490}, url={http://dx.doi.org/10.1152/ajpregu.00051.2020}, DOI={10.1152/ajpregu.00051.2020}, abstractNote={γ-Butyrobetaine hydroxylase (γ-BBH) is the last limiting enzyme of the l-carnitine biosynthesis pathway and plays an important role in catalyzing the hydroxylation of γ-butyrobetaine (γ-BB) to l-carnitine. To study the developmental effect of substrate concentration on the enzyme’s specific activity, kinetics of γ-BBH were measured in liver and kidney from newborn and 1-, 7-, 21-, 35-, 56-, and 210-day-old domestic pigs. Fresh tissue homogenates were assayed under nine concentrations of γ-BB from 0 to 1.5 mM. Substrate inhibition associated with age was observed at ≥0.6 mM of γ-BB. Hepatic activity was low at birth but increased after 1 day. By 21 days, the activity rose by 6.6-fold ( P < 0.05) and remained constant after 56 days. Renal activity was higher than in liver at birth but remained constant through 35 days. By 56 days, the velocity increased by 44% over the activity at birth ( P < 0.05). The apparent Km}, number={1}, journal={American Journal of Physiology-Regulatory, Integrative and Comparative Physiology}, publisher={American Physiological Society}, author={Lin, Xi and Lyvers Peffer, Pasha A. and Woodworth, Jason and Odle, Jack}, year={2020}, month={Jul}, pages={R43–R49} } @article{huang_luo_xiao_lin_spears_2020, title={Research Note: Responses of growth performance, immune traits, and small intestinal morphology to dietary supplementation of chromium propionate in heat-stressed broilers}, volume={99}, ISSN={0032-5791}, url={http://dx.doi.org/10.1016/j.psj.2020.07.005}, DOI={10.1016/j.psj.2020.07.005}, number={10}, journal={Poultry Science}, publisher={Elsevier BV}, author={Huang, Y.L. and Luo, Q.H. and Xiao, F. and Lin, X. and Spears, J.W.}, year={2020}, month={Oct}, pages={5070–5073} } @article{magnuson_liu_sun_tolba_xi_whelan_lei_2020, title={Supplemental methionine and stocking density affect antioxidant status, fatty acid profiles, and growth performance of broiler chickens}, volume={98}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.1093/jas/skaa092}, DOI={10.1093/jas/skaa092}, abstractNote={Abstract Broilers stocked in high densities may be prone to oxidative and inflammatory insults, resulting in impaired health status, growth performance, and meat quality. This study was to determine if 30% extra supplemental dl-methionine alleviated or prevented those adverse effects of a higher stocking density in broiler chickens. A total of 560 male Cornish Cross cockerels (day old) were divided into four groups: two stocking densities (9 and 12 birds/m2) and two supplementations of methionine (grower: 2.90 or 3.77 g/kg and finisher: 2.60 or 3.38 g/kg). Growth performance was recorded weekly. Blood and tissues were sampled at the end of each period. High stocking density decreased (P < 0.05) body weight and growth performance of growers and (or) finishers. Those differences were partially attenuated by the extra methionine supplementation. The high methionine elevated (P < 0.05) glutathione (GSH) concentration in the thigh at both ages (> 24%). The high stocking density elevated (>28%, P < 0.05) glutathione concentration in the plasma, breast, and thigh of growers, but decreased (P < 0.05) it in the liver of growers and thigh of finishers. Interaction effects (P < 0.05) between dietary methionine and stocking density were found on activities of the antioxidant enzyme glutathione S-transferase in the liver of growers and breast, thigh, and adipose tissue of finishers. The interaction effect was also found on activities of glutathione peroxidase and superoxide dismutase in the thigh of growers. The extra methionine decreased (P < 0.05) hepatic gene expression of heat shock protein 90 (18%) and thigh and breast malondialdehyde concentrations of the finishers (35%). In conclusion, the 30% extra dl-methionine supplementation was able to partially mitigate adverse effects caused by the higher stocking density and to improve the redox status of the broilers.}, number={4}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Magnuson, Andrew D and Liu, Guanchen and Sun, Tao and Tolba, Samar A and Xi, Lin and Whelan, Rose and Lei, Xin Gen}, year={2020}, month={Mar} } @article{magnuson_liu_sun_tolba_fahrenholz_xi_whelan_lei_2019, title={125 Supplementing extra dietary DL-methionine mitigates effects of higher stocking density on growth performance, meat quality, and health status of broiler chicks}, volume={97}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.1093/jas/skz258.228}, DOI={10.1093/jas/skz258.228}, abstractNote={Abstract This study was to determine if 30% extra supplemental DL-methionine could improve growth performance, meat quality, and health status of broilers stocked at a high density. A total of 560 day-old male Cornish cockerel chicks were divided into 4 treatment groups: 2 stocking densities (2.9 and 3.8 kg/ft2) and 2 supplementations of DL-methionine (grower: 2.90 or 3.77 g/kg and finisher: 2.60 or 3.38 g/kg). Chicks were fed the same corn-soybean meal-based starter diet and then experimental diets (grower: 6.4 g SAA/kg, finisher: 5.9 g SAA/kg, n = 10 pens/treatment). Growth performance and mortality were recorded, and blood and tissue samples (3 chicks/pen) were collected at the end of each period. Data were analyzed by two-way ANOVA. High stocking density decreased (P < 0.05) BW and (or) ADG of growers and finishers. Both high stocking density and methionine decreased (P < 0.05) ADFI and the high methionine improved (P < 0.05) feed use efficiency of chicks during the grower-finisher period. Neither treatment affected feather coverage, mortality, incidences of diseases, or dressing percentage. The high methionine improved (P < 0.05) meat to bone ratio of thigh, and exerted mixed effects (P < 0.05) on texture of breast and thigh. Dietary methionine and stocking density showed no major effects on tissue lipid profiles, but moderate effects (P < 0.05) on plasma concentrations of total cholesterol and(or) triglycerides of chicks. Fatty acid profiles in the liver and breast of chicks were unaffected by either treatment. The two treatments enhanced (P < 0.05) tibial maximum breaking strength (15–20%) and plasma alkaline phosphatase activity of growers. In conclusion, the high stocking density affected growth performance, meat quality, and health status of broilers. Supplementing 30% extra dietary methionine seemed to mitigate some of those effects. (Supported in part by Evonik Nutrition & Care GmbH, Germany)}, number={Supplement_3}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Magnuson, Andrew and Liu, Guanchen and Sun, Tao and Tolba, Samar and Fahrenholz, Adam and Xi, L and Whelan, Rose and Lei, Xingen}, year={2019}, month={Dec}, pages={111–111} } @article{walter_lin_jacobi_käser_esposito_odle_2019, title={Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages}, volume={10}, ISSN={2049-1891}, url={http://dx.doi.org/10.1186/s40104-019-0321-1}, DOI={10.1186/s40104-019-0321-1}, number={1}, journal={Journal of Animal Science and Biotechnology}, publisher={Springer Science and Business Media LLC}, author={Walter, Kathleen R. and Lin, Xi and Jacobi, Sheila K. and Käser, Tobias and Esposito, Debora and Odle, Jack}, year={2019}, month={Feb} } @article{zhang_xu_liu_zhang_odle_lin_zhu_wang_liu_2019, title={EPA and DHA Inhibit Myogenesis and Downregulate the Expression of Muscle-related Genes in C2C12 Myoblasts}, volume={10}, ISSN={2073-4425}, url={http://dx.doi.org/10.3390/genes10010064}, DOI={10.3390/genes10010064}, abstractNote={This study was conducted to elucidate the biological effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on cell proliferation, differentiation and gene expression in C2C12 myoblasts. C2C12 were treated with various concentrations of EPA or DHA under proliferation and differentiation conditions. Cell viability was analyzed using cell counting kit-8 assays (CCK-8). The Edu assays were performed to analyze cell proliferation. To analyze cell differentiation, the expressions of myogenic marker genes were determined at the transcriptional and translational levels by qRT-PCR, immunoblotting and immunofluorescence. Global gene expression patterns were characterized using RNA-sequencing. Phosphorylation levels of ERK and Akt were examined by immunoblotting. Cell viability and proliferation was significantly inhibited after incubation with EPA (50 and 100 μM) or DHA (100 μM). Both EPA and DHA suppressed C2C12 myoblasts differentiation. RNA-sequencing analysis revealed that some muscle-related genes were significantly downregulated following EPA or DHA (50 μM) treatment, including insulin-like growth factor 2 (IGF-2), troponin T3 (Tnnt3), myoglobin (Mb), myosin light chain phosphorylatable fast skeletal muscle (Mylpf) and myosin heavy polypeptide 3 (Myh3). IGF-2 was crucial for the growth and differentiation of skeletal muscle and could activate the PI3K/Akt and the MAPK/ERK cascade. We found that EPA and DHA (50 μM) decreased the phosphorylation levels of ERK1/2 and Akt in C2C12 myoblasts. Thus, this study suggested that EPA and DHA exerted an inhibitory effect on myoblast proliferation and differentiation and downregulated muscle-related genes expression.}, number={1}, journal={Genes}, publisher={MDPI AG}, author={Zhang, Jing and Xu, Xin and Liu, Yan and Zhang, Lin and Odle, Jack and Lin, Xi and Zhu, Huiling and Wang, Xiuying and Liu, Yulan}, year={2019}, month={Jan}, pages={64} } @article{xiao_liu_qin_zhang_wang_zhang_odle_lin_hu_liu_2019, title={EPA and DHA attenuate deoxynivalenol‐induced intestinal porcine epithelial cell injury and protect barrier function integrity by inhibiting necroptosis signaling pathway}, volume={34}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fj.201902298R}, DOI={10.1096/fj.201902298R}, number={2}, journal={The FASEB Journal}, publisher={Wiley}, author={Xiao, Kan and Liu, Congcong and Qin, Qin and Zhang, Yang and Wang, Xiuying and Zhang, Jing and Odle, Jack and Lin, Xi and Hu, Chien‐An Andy and Liu, Yulan}, year={2019}, month={Dec}, pages={2483–2496} } @article{liao_zhu_lu_li_zhang_ji_lin_luo_2019, title={Maternal manganese activates anti-apoptotic-related gene expressions via miR-1551 and miR-34c in embryonic hearts from maternal heat stress (Gallus gallus)}, volume={84}, ISSN={0306-4565}, url={http://dx.doi.org/10.1016/j.jtherbio.2019.07.014}, DOI={10.1016/j.jtherbio.2019.07.014}, journal={Journal of Thermal Biology}, publisher={Elsevier BV}, author={Liao, Xiudong and Zhu, Yongwen and Lu, Lin and Li, Wenxiang and Zhang, Liyang and Ji, Cheng and Lin, Xi and Luo, Xugang}, year={2019}, month={Aug}, pages={190–199} } @article{martinez padilla_silva-guillen_moran_lin_odle_heugten_2019, title={PSV-11 Effects of plasma protein on growth performance and intestinal health of weaned pigs}, volume={97}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.1093/jas/skz122.346}, DOI={10.1093/jas/skz122.346}, abstractNote={Abstract This study was conducted to evaluate the effects of using plasma protein (PP) as a highly digestible, functional protein source in nursery pig diets on growth performance and intestinal health. Pigs (n = 64; 6.53 ± 0.12 kg BW) weaned at 21 d of age were blocked by litter and BW and randomly assigned within blocks to 1 of 2 dietary treatments in a 35-d study. Four pigs were housed per pen, using a total of 16 pens (8 replicate pens per treatment). Treatments were: 1) control diet (without growth-promoting minerals or antibiotics) without PP, and 2) control diet with 4% of PP replacing SBM on a 1:1 basis. Diets were fed in 3 feeding phases (7, 14, and 14 days, respectively) and PP was included in all phases. Supplementation of PP tended (P = 0.07) to increase ADG (204 vs. 150 g/d) and improved (P = 0.02) gain:feed (812 vs 572 g/kg) during wk 2 only. Individual diarrhea scores (scale from 0=very hard to 6=watery diarrhea) determined using fecal loops changed over time (P < 0.001; 2.1, 2.4, 4.1 and 3.5 for d 1, 3, 7, and 14 respectively), but were not affected by PP. No differences were detected for intestinal morphology measured on d 35 in duodenum, jejunum and ileum. Cell proliferation using Ki-67 staining was increased by PP (86.6 vs. 72.2 positive cells) only in the ileum (P = 0.03). No differences in mucosal concentrations of IL-10, TNF-α, and IFN-γ in the duodenum, jejunum or ileum were detected. Number of eosinophils in blood decreased (14.1 vs. 34.8 cells/µL; P = 0.004), while red blood cell counts (5.9 vs 6.2 x 106 cells/µL; P = 0.09) and neutrophil counts (529 vs. 695 cells/µL; P = 0.07) tended to decrease with PP. Results suggest that PP was not effective in improving overall growth performance and had minimal effects on intestinal health of weanling pigs.}, number={Supplement_2}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Martinez Padilla, Gabriela E and Silva-Guillen, Ysenia Victoria and Moran, Kory and Lin, Xi and Odle, Jack and Heugten, Eric van}, year={2019}, month={Jul}, pages={197–197} } @article{sun_lu_liao_zhang_lin_luo_ma_2018, title={Effect of In Ovo Zinc Injection on the Embryonic Development and Epigenetics-Related Indices of Zinc-Deprived Broiler Breeder Eggs}, volume={185}, ISSN={0163-4984 1559-0720}, url={http://dx.doi.org/10.1007/s12011-018-1260-y}, DOI={10.1007/s12011-018-1260-y}, number={2}, journal={Biological Trace Element Research}, publisher={Springer Science and Business Media LLC}, author={Sun, Xiaoming and Lu, Lin and Liao, Xiudong and Zhang, Liyang and Lin, Xi and Luo, Xugang and Ma, Qiugang}, year={2018}, month={Feb}, pages={456–464} } @article{sun_liao_lu_zhang_ma_xi_luo_2018, title={Effect of in ovo zinc injection on the embryonic development, tissue zinc contents, antioxidation, and related gene expressions of broiler breeder eggs}, volume={17}, ISSN={2095-3119}, url={http://dx.doi.org/10.1016/S2095-3119(17)61704-0}, DOI={10.1016/S2095-3119(17)61704-0}, number={3}, journal={Journal of Integrative Agriculture}, publisher={Elsevier BV}, author={Sun, Xiao Ming and Liao, Xiu Dong and Lu, Lin and Zhang, Li Yang and Ma, Qiu Gang and Xi, Lin and Luo, Xu Gang}, year={2018}, month={Mar}, pages={648–656} } @article{liao_li_zhu_zhang_lu_lin_luo_2018, title={Effects of environmental temperature and dietary zinc on egg production performance, egg quality and antioxidant status and expression of heat-shock proteins in tissues of broiler breeders}, volume={120}, ISSN={0007-1145 1475-2662}, url={http://dx.doi.org/10.1017/S0007114518001368}, DOI={10.1017/S0007114518001368}, abstractNote={Abstract}, number={1}, journal={British Journal of Nutrition}, publisher={Cambridge University Press (CUP)}, author={Liao, Xiudong and Li, Wenxiang and Zhu, Yongwen and Zhang, Liyang and Lu, Lin and Lin, Xi and Luo, Xugang}, year={2018}, month={Jun}, pages={3–12} } @article{shim_jacobi_odle_lin_2018, title={Pharmacologic activation of peroxisome proliferator-activating receptor-α accelerates hepatic fatty acid oxidation in neonatal pigs}, volume={9}, ISSN={1949-2553}, url={http://dx.doi.org/10.18632/oncotarget.25199}, DOI={10.18632/oncotarget.25199}, number={35}, journal={Oncotarget}, publisher={Impact Journals, LLC}, author={Shim, Kwanseob and Jacobi, Sheila and Odle, Jack and Lin, Xi}, year={2018}, month={May}, pages={23900–23914} } @article{liu_zhao_fan_xi_zhang_ji_ma_rong_2017, title={876 Effects of sporoderm-broken spores of Ganoderma lucidum on growth performance, antioxidant function, and immune response of broiler chickens}, volume={95}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/asasann.2017.876}, DOI={10.2527/asasann.2017.876}, number={suppl_4}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Liu, T. and Zhao, L. and Fan, Y. and Xi, L. and Zhang, J. and Ji, C. and Ma, Q. and Rong, X.}, year={2017}, month={Aug}, pages={375–375} } @article{he_khan_bai_odle_xi_2017, title={Activation of PPARα by Oral Clofibrate Increases Renal Fatty Acid Oxidation in Developing Pigs}, volume={18}, ISSN={1422-0067}, url={http://dx.doi.org/10.3390/ijms18122663}, DOI={10.3390/ijms18122663}, number={12}, journal={International Journal of Molecular Sciences}, publisher={MDPI AG}, author={He, Yonghui and Khan, Imad and Bai, Xiumei and Odle, Jack and Xi, Lin}, year={2017}, month={Dec}, pages={2663} } @article{jacobi_xi_maltecca_borst_smith_odle_2017, title={Dietary Prebiotics and Arachidonic Acid (ARA) Modulate Intestinal Injury and Microbial Taxa Following Acute Dextran Sodium Sulfate Induced Colitis in Formula‐Fed Piglets}, volume={31}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.31.1_supplement.lb324}, DOI={10.1096/fasebj.31.1_supplement.lb324}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Jacobi, Sheila K. and Xi, Lin and Maltecca, Christian and Borst, Luke and Smith, Andrew and Odle, Jack}, year={2017}, month={Apr} } @article{walter_xi_jacobi_esposito_odle_2017, title={Dietary long-chain PUFAs enrich porcine alveolar macrophages and alter Prostaglandin E-2 Production Following LPS Challenge}, volume={31}, journal={FASEB Journal}, author={Walter, K. R. and Xi, L and Jacobi, S.K. and Esposito, D. and Odle, J.}, year={2017} } @article{thorpe_xi_maltecca_walters_smith_odle_jacobi_2017, title={Dietary prebiotics and arachidonic acid alter intestinal phospholipid composition and time-dependently change fecal microbiome in formula-fed piglets}, volume={31}, journal={FASEB Journal}, author={Thorpe, M. K., Xi and Xi, L. and Maltecca, C. and Walters, K.R. and Smith, A. and Odle, J. and Jacobi, S. K.}, year={2017} } @article{pike_zhao_hicks_zhang_smith_liu_odle_xi_2017, title={Effect of Medium Chain Triglycerides on TCA and Ketogenic Capacity of Proximal Intestinal Fatty Acid Oxidation in Clofibrate Feed Newborn Pigs}, volume={31}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.31.1_supplement.654.4}, DOI={10.1096/fasebj.31.1_supplement.654.4}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Pike, Brandon Edward and Zhao, Jinan and Hicks, Julie and Zhang, Yong and Smith, Andrew and Liu, Hsiao‐Ching and Odle, Jack and Xi, Lin}, year={2017}, month={Apr} } @article{zhao_pike_zhang_sabin_smith_zhu_odle_xi_2017, title={Effects of Dietary Anaplerotic Carbon Sources and Ketogenic Fatty Acids on Hepatic Fatty Acid Oxidation in Neonatal Pigs}, volume={31}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.31.1_supplement.653.10}, DOI={10.1096/fasebj.31.1_supplement.653.10}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Zhao, Jinan and Pike, Brandon and Zhang, Yong and Sabin, Sean and Smith, Andrew and Zhu, Yongwen and Odle, Jack and Xi, Lin}, year={2017}, month={Apr} } @article{feng_gong_zhao_lin_liu_ma_2017, title={Effects of dietary supplementation of resveratrol on performance, egg quality, yolk cholesterol and antioxidant enzyme activity of laying hens}, volume={58}, ISSN={0007-1668 1466-1799}, url={http://dx.doi.org/10.1080/00071668.2017.1349295}, DOI={10.1080/00071668.2017.1349295}, number={5}, journal={British Poultry Science}, publisher={Informa UK Limited}, author={Feng, Z. H. and Gong, J. G. and Zhao, G. X. and Lin, X. and Liu, Y. C. and Ma, K. W.}, year={2017}, month={Sep}, pages={544–549} } @article{zhu_li_lu_zhang_ji_lin_liu_odle_luo_2017, title={Impact of maternal heat stress in conjunction with dietary zinc supplementation on hatchability, embryonic development, and growth performance in offspring broilers}, volume={96}, ISSN={0032-5791}, url={http://dx.doi.org/10.3382/ps/pew481}, DOI={10.3382/ps/pew481}, number={7}, journal={Poultry Science}, publisher={Elsevier BV}, author={Zhu, Y.W. and Li, W.X. and Lu, L. and Zhang, L.Y. and Ji, C. and Lin, X. and Liu, H.C. and Odle, J. and Luo, X.G.}, year={2017}, month={Jul}, pages={2351–2359} } @article{qin_liao_lu_zhang_xi_guo_luo_2017, title={Manganese enhances the expression of the manganese superoxide dismutase in cultured primary chick embryonic myocardial cells}, volume={16}, ISSN={2095-3119}, url={http://dx.doi.org/10.1016/S2095-3119(16)61527-7}, DOI={10.1016/S2095-3119(16)61527-7}, number={9}, journal={Journal of Integrative Agriculture}, publisher={Elsevier BV}, author={Qin, Shi Zhen and Liao, Xiu Dong and Lu, Lin and Zhang, Li Yang and Xi, Lin and Guo, Yan Li and Luo, Xu Gang}, year={2017}, month={Sep}, pages={2038–2046} } @article{zhu_lu_liao_li_zhang_ji_lin_liu_odle_luo_et al._2017, title={Maternal dietary manganese protects chick embryos against maternal heat stress via epigenetic-activated antioxidant and anti-apoptotic abilities}, volume={8}, ISSN={1949-2553}, url={http://dx.doi.org/10.18632/oncotarget.20804}, DOI={10.18632/oncotarget.20804}, number={52}, journal={Oncotarget}, publisher={Impact Journals, LLC}, author={Zhu, Y. W. and Lu, L. and Liao, X. D. and Li, W. X. and Zhang, L. Y. and Ji, C. and Lin, X. and Liu, H. C. and Odle, J. and Luo, X. G. and et al.}, year={2017}, month={Sep}, pages={89665–89680} } @article{zhu_liao_lu_li_zhang_ji_lin_liu_odle_luo_et al._2017, title={Maternal dietary zinc supplementation enhances the epigenetic-activated antioxidant ability of chick embryos from maternal normal and high temperatures}, volume={8}, ISSN={1949-2553}, url={http://dx.doi.org/10.18632/oncotarget.15057}, DOI={10.18632/oncotarget.15057}, number={12}, journal={Oncotarget}, publisher={Impact Journals, LLC}, author={Zhu, Y. W. and Liao, X. D. and Lu, L. and Li, W. X. and Zhang, L. Y. and Ji, C. and Lin, X. and Liu, H. C. and Odle, J. and Luo, X. and et al.}, year={2017}, month={Feb}, pages={19814–19824} } @article{lima_lin_jacobi_man_sommer_flowers_blikslager_gonzalez_odle_2017, title={Supplementation of Maternal Diets with Docosahexaenoic Acid and Methylating Vitamins Impacts Growth and Development of Fetuses from Malnourished Gilts}, volume={2}, ISSN={2475-2991}, url={http://dx.doi.org/10.3945/cdn.117.001958}, DOI={10.3945/cdn.117.001958}, number={3}, journal={Current Developments in Nutrition}, publisher={Oxford University Press (OUP)}, author={Lima, Hope K and Lin, Xi and Jacobi, Sheila K and Man, Caolai and Sommer, Jeffrey and Flowers, William and Blikslager, Anthony and Gonzalez, Liara and Odle, Jack}, year={2017}, month={Dec} } @article{chen_liu_wang_wang_li_shi_zhu_zhang_pi_hu_et al._2016, title={Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge}, volume={22}, ISSN={1753-4259 1753-4267}, url={http://dx.doi.org/10.1177/1753425916664124}, DOI={10.1177/1753425916664124}, abstractNote={ Asparagine (Asn), an activator of ornithine decarboxylase (ODC), stimulates cell proliferation in intestinal epithelial cells. We hypothesized that Asn can mitigate LPS-induced injury of intestinal structure and barrier function by regulating inflammatory signaling pathways. We executed the following experiment using weanling pigs for each of the groups: (1) non-challenged control; (2) LPS-challenged control; (3) LPS + 0.5% Asn; (4) LPS + 1.0% Asn. After 21-d feeding, pigs received an i.p. injection of either saline or LPS. Four h after injection, the mid-jejunum and mid-ileum samples were collected. We found that Asn restored ODC expression that was decreased by LPS treatment. Asn also restored intestinal morphology and barrier function that were impaired by LPS treatment. In addition, Asn down-regulated intestinal caspase-3 protein expression and TNF-α concentration, and decreased the mRNA expression of intestinal TLR4, TLR4 downstream signals (myeloid differentiation factor 88, IL-1 receptor-associated kinase 1 and TNF-α receptor-associated factor 6 and NOD1, NOD2 and their adaptor molecule (receptor-interacting serine/threonine-protein kinase 2). Moreover, Asn decreased p38 phosphorylation but increased ERK1/2 phosphorylation. Our results suggest that Asn improves intestinal integrity during an inflammatory insult, which appears to be related to the decrease of intestinal pro-inflammatory cytokine (via TLR4, NODs and p38) and of enterocyte apoptosis (via p38 and ERK1/2). }, number={8}, journal={Innate Immunity}, publisher={SAGE Publications}, author={Chen, Shaokui and Liu, Yulan and Wang, Xiuying and Wang, Haibo and Li, Shuang and Shi, Haifeng and Zhu, Huiling and Zhang, Jing and Pi, Dingan and Hu, Chien-An Andy and et al.}, year={2016}, month={Sep}, pages={577–587} } @article{wang_liu_wang_pi_leng_zhu_zhang_shi_li_lin_et al._2016, title={Asparagine reduces the mRNA expression of muscle atrophy markers via regulating protein kinase B (Akt), AMP-activated protein kinase α, toll-like receptor 4 and nucleotide-binding oligomerisation domain protein signalling in weaning piglets after lipopolysaccharide challenge}, volume={116}, ISSN={0007-1145 1475-2662}, url={http://dx.doi.org/10.1017/S000711451600297X}, DOI={10.1017/S000711451600297X}, abstractNote={Abstract}, number={7}, journal={British Journal of Nutrition}, publisher={Cambridge University Press (CUP)}, author={Wang, Xiuying and Liu, Yulan and Wang, Shuhui and Pi, Dingan and Leng, Weibo and Zhu, Huiling and Zhang, Jing and Shi, Haifeng and Li, Shuang and Lin, Xi and et al.}, year={2016}, month={Aug}, pages={1188–1198} } @article{zhu_lu_li_zhang_ji_lin_liu_odle_luo_2016, title={Effect of dietary manganese on antioxidant status and expressions of heat shock proteins and factors in tissues of laying broiler breeders under normal and high environmental temperatures}, volume={116}, ISSN={0007-1145 1475-2662}, url={http://dx.doi.org/10.1017/S0007114516003822}, DOI={10.1017/S0007114516003822}, abstractNote={Abstract}, number={11}, journal={British Journal of Nutrition}, publisher={Cambridge University Press (CUP)}, author={Zhu, Yong-Wen and Lu, Lin and Li, Wen-Xiang and Zhang, Li-Yang and Ji, Cheng and Lin, Xi and Liu, Hsiao-Ching and Odle, Jack and Luo, Xu-Gang}, year={2016}, month={Nov}, pages={1851–1860} } @article{xiao_ao_zhou_spears_lin_huang_2016, title={Effects of Supplemental Chromium Propionate on Serum Lipids, Carcass Traits, and Meat Quality of Heat-Stressed Broilers}, volume={176}, ISSN={0163-4984 1559-0720}, url={http://dx.doi.org/10.1007/s12011-016-0852-7}, DOI={10.1007/s12011-016-0852-7}, number={2}, journal={Biological Trace Element Research}, publisher={Springer Science and Business Media LLC}, author={Xiao, Fang and Ao, Degulina and Zhou, Bo and Spears, Jerry W and Lin, Xi and Huang, Yanling}, year={2016}, month={Sep}, pages={401–406} } @inproceedings{sabin_xi_2016, title={Effects of increasing krebs cycle capacity by providing anaplerotic carbon and ketogenic fatty acids on palmitic acid oxidation in kidney of neonatal piglets}, author={Sabin, S. and Xi, L.}, year={2016} } @article{li_lu_liao_gao_wang_zhang_xi_liu_luo_2016, title={Manganese elevates manganese superoxide dismutase protein level through protein kinase C and protein tyrosine kinase}, volume={29}, ISSN={0966-0844 1572-8773}, url={http://dx.doi.org/10.1007/s10534-016-9913-9}, DOI={10.1007/s10534-016-9913-9}, number={2}, journal={BioMetals}, publisher={Springer Science and Business Media LLC}, author={Li, Sufen and Lu, Lin and Liao, Xiudong and Gao, Tianquan and Wang, Funing and Zhang, Liyang and Xi, Lin and Liu, Songbai and Luo, Xugang}, year={2016}, month={Feb}, pages={265–274} } @article{jacobi_moeser_borst_lin_odle_2015, title={Acute Dextran Sodium Sulfate Dose‐Dependently Induces Colitis in Formula‐Fed Piglets}, volume={29}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.29.1_supplement.755.8}, DOI={10.1096/fasebj.29.1_supplement.755.8}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Jacobi, Sheila and Moeser, Adam and Borst, Luke and Lin, Xi and Odle, Jack}, year={2015}, month={Apr} } @article{huang_yang_xiao_lloyd_lin_2015, title={Effects of Supplemental Chromium Source and Concentration on Growth Performance, Carcass Traits, and Meat Quality of Broilers Under Heat Stress Conditions}, volume={170}, ISSN={0163-4984 1559-0720}, url={http://dx.doi.org/10.1007/s12011-015-0443-z}, DOI={10.1007/s12011-015-0443-z}, number={1}, journal={Biological Trace Element Research}, publisher={Springer Science and Business Media LLC}, author={Huang, Yanling and Yang, Jian and Xiao, Fang and Lloyd, Karen and Lin, Xi}, year={2015}, month={Jul}, pages={216–223} } @article{zheng_huang_xiao_lin_lloyd_2015, title={Effects of Supplemental Chromium Source and Concentration on Growth, Carcass Characteristics, and Serum Lipid Parameters of Broilers Reared Under Normal Conditions}, volume={169}, ISSN={0163-4984 1559-0720}, url={http://dx.doi.org/10.1007/s12011-015-0419-z}, DOI={10.1007/s12011-015-0419-z}, number={2}, journal={Biological Trace Element Research}, publisher={Springer Science and Business Media LLC}, author={Zheng, Cancai and Huang, Yanling and Xiao, Fang and Lin, Xi and Lloyd, Karen}, year={2015}, month={Jul}, pages={352–358} } @inproceedings{zhao_pike_sabin_odle_xi_2015, title={Effects of TCA cycle and ketogenic capacity on fatty acid oxidation induced by clofibrate in suckling neonatal pigs}, author={Zhao, Jinan and Pike, Brandon and Sabin, Sean and Odle, Jack and Xi, Lin}, year={2015} } @article{xie_tang_lu_zhang_lin_liu_odle_luo_2015, title={Effects of acute and chronic heat stress on plasma metabolites, hormones and oxidant status in restrictedly fed broiler breeders}, volume={94}, ISSN={0032-5791}, url={http://dx.doi.org/10.3382/ps/pev105}, DOI={10.3382/ps/pev105}, number={7}, journal={Poultry Science}, publisher={Elsevier BV}, author={Xie, Jingjing and Tang, Li and Lu, Lin and Zhang, Liyang and Lin, Xi and Liu, Hsiao-Ching and Odle, Jack and Luo, Xugang}, year={2015}, month={Jul}, pages={1635–1644} } @article{zhu_xie_li_lu_zhang_ji_lin_liu_odle_luo_2015, title={Effects of environmental temperature and dietary manganese on egg production performance, egg quality, and some plasma biochemical traits of broiler breeders}, volume={93}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/jas.2015-8956}, DOI={10.2527/jas.2015-8956}, number={7}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Zhu, Y. W. and Xie, J. J. and Li, W. X. and Lu, L. and Zhang, L. Y. and Ji, C. and Lin, X. and Liu, H. C. and Odle, J. and Luo, X. G.}, year={2015}, month={Jul}, pages={3431–3440} } @article{zhu_lu_li_zhang_ji_lin_liu_odle_luo_2015, title={Effects of maternal dietary manganese and incubation temperature on hatchability, antioxidant status, and expression of heat shock proteins in chick embryos}, volume={93}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/jas.2015-9610}, DOI={10.2527/jas.2015-9610}, number={12}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Zhu, Y. W. and Lu, L. and Li, W. X. and Zhang, L. Y. and Ji, C. and Lin, X. and Liu, H. C. and Odle, J. and Luo, X. G.}, year={2015}, month={Dec}, pages={5725–5734} } @article{bai_yan_xie_hu_lin_wu_zhou_wang_see_2015, title={Effects of pre-slaughter stressor and feeding preventative Chinese medicinal herbs on glycolysis and oxidative stability in pigs}, volume={87}, ISSN={1344-3941}, url={http://dx.doi.org/10.1111/asj.12537}, DOI={10.1111/asj.12537}, number={8}, journal={Animal Science Journal}, publisher={Wiley}, author={Bai, Xiumei and Yan, Xue and Xie, Linqi and Hu, Xiaodong and Lin, Xi and Wu, Changzheng and Zhou, Ningcong and Wang, Anru and See, Miles Todd}, year={2015}, month={Oct}, pages={1028–1033} } @article{man_fan_lima_jacobi_lui_odle_xi_2015, title={Maternal Undernutrition Affects Expression of Genes Associated with Ileal Development and Metabolism in Full‐term Offspring}, volume={29}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.29.1_supplement.754.13}, DOI={10.1096/fasebj.29.1_supplement.754.13}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Man, Chaolai and Fan, Yu and Lima, Hope and Jacobi, Sheila and Lui, Sunny and Odle, Jack and Xi, Lin}, year={2015}, month={Apr} } @article{fan_zhao_ji_li_jia_xi_zhang_ma_2015, title={Protective Effects of Bacillus subtilis ANSB060 on Serum Biochemistry, Histopathological Changes and Antioxidant Enzyme Activities of Broilers Fed Moldy Peanut Meal Naturally Contaminated with Aflatoxins}, volume={7}, ISSN={2072-6651}, url={http://dx.doi.org/10.3390/toxins7083330}, DOI={10.3390/toxins7083330}, number={8}, journal={Toxins}, publisher={MDPI AG}, author={Fan, Yu and Zhao, Lihong and Ji, Cheng and Li, Xiaoying and Jia, Ru and Xi, Lin and Zhang, Jianyun and Ma, Qiugang}, year={2015}, month={Aug}, pages={3330–3343} } @article{xi_man_lima_jacobi_lui_odle_2015, title={Supplementation of Maternal Diets with Choline, B‐vitamin and Docosahexaenoic Acid (DHA) Alters Gene Expressions Associated with Hepatic Lipid Metabolism in Offspring}, volume={29}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.29.1_supplement.749.9}, DOI={10.1096/fasebj.29.1_supplement.749.9}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Xi, Lin and Man, Chaolai and Lima, Hope and Jacobi, Sheila and Lui, Sunny and Odle, Jack}, year={2015}, month={Apr} } @article{lin_jacobi_odle_2015, title={Transplacental induction of fatty acid oxidation in term fetal pigs by the peroxisome proliferator-activated receptor alpha agonist clofibrate}, volume={6}, ISSN={2049-1891}, url={http://dx.doi.org/10.1186/s40104-015-0010-7}, DOI={10.1186/s40104-015-0010-7}, number={1}, journal={Journal of Animal Science and Biotechnology}, publisher={Springer Science and Business Media LLC}, author={Lin, Xi and Jacobi, Sheila and Odle, Jack}, year={2015}, month={Mar} } @article{bai_lin_drayton_liu_ji_odle_2014, title={Clofibrate Increases Long-Chain Fatty Acid Oxidation by Neonatal Pigs}, volume={144}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.3945/jn.114.193169}, DOI={10.3945/jn.114.193169}, number={11}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Bai, Xiumei and Lin, Xi and Drayton, Josephine and Liu, Yulan and Ji, Cheng and Odle, Jack}, year={2014}, month={Sep}, pages={1688–1693} } @article{pi_liu_shi_li_odle_lin_zhu_chen_hou_leng_et al._2014, title={Dietary supplementation of aspartate enhances intestinal integrity and energy status in weanling piglets after lipopolysaccharide challenge}, volume={25}, ISSN={0955-2863}, url={http://dx.doi.org/10.1016/j.jnutbio.2013.12.006}, DOI={10.1016/j.jnutbio.2013.12.006}, number={4}, journal={The Journal of Nutritional Biochemistry}, publisher={Elsevier BV}, author={Pi, D. and Liu, Y. and Shi, H. and Li, S. and Odle, J. and Lin, X. and Zhu, H. and Chen, F. and Hou, Y. and Leng, W. and et al.}, year={2014}, month={Apr}, pages={456–462} } @article{xie_tang_lu_zhang_xi_liu_odle_luo_2014, title={Differential expression of heat shock transcription factors and heat shock proteins after acute and chronic heat stress in laying chickens (Gallus gallus)}, volume={9}, ISSN={1932-6203}, url={http://dx.doi.org/10.1371/journal.pone.0102204}, DOI={10.1371/journal.pone.0102204}, number={7}, journal={PLoS One}, publisher={Public Library of Science (PLoS)}, author={Xie, J. J. and Tang, L. and Lu, L. and Zhang, L. Y. and Xi, L. and Liu, H-C and Odle, J. and Luo, X. G.}, editor={Cotterill, SueEditor}, year={2014}, pages={e102204} } @article{huang_wang_lin_guo_2014, title={Effects of Supplemental Copper on the Serum Lipid Profile, Meat Quality, and Carcass Composition of Goat Kids}, volume={159}, ISSN={0163-4984 1559-0720}, url={http://dx.doi.org/10.1007/s12011-014-9976-9}, DOI={10.1007/s12011-014-9976-9}, number={1-3}, journal={Biological Trace Element Research}, publisher={Springer Science and Business Media LLC}, author={Huang, Yanling and Wang, Yong and Lin, Xi and Guo, Chunhua}, year={2014}, month={Apr}, pages={140–146} } @inproceedings{lima_jacobi_man_walker_sommer_flowers_blikslager_gonzalez_xi_odle_2014, title={Effects of methylating vitamins and docosahexaenoic acid supplementation on biological molecular, and genomic characteristics of intra-uterine growth restriction (IUGR) in a feed-restricted swine model}, booktitle={Swine in Biomedical Research}, author={Lima, Hope and Jacobi, Sheila and Man, Chaolai and Walker, Kaitlyn and Sommer, Jeffrey and Flowers, William and Blikslager, Anthony and Gonzalez, Liara and Xi, Lin and Odle, Jack}, year={2014}, pages={60} } @article{lima_jacobi_man_walker_sommer_flowers_blikslager_xi_odle_2014, title={Effects of methylating vitamins and docosahexaenoic acid supplementation on intra‐uterine growth retardation in a feed‐restricted swine model}, volume={28}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.28.1_supplement.1033.8}, DOI={10.1096/fasebj.28.1_supplement.1033.8}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Lima, Hope and Jacobi, Sheila and Man, Chaolai and Walker, Kaitlyn and Sommer, Jeffrey and Flowers, William and Blikslager, Anthony and Xi, Lin and Odle, Jack}, year={2014}, month={Apr} } @inproceedings{man_xi_lima_jacobi_resnyk_liu_odle_2014, title={Maternal supplementation of choline, B-vitamins and docosahexaneoic acid (DHA) during global nutrient restriction alter abundance of miRNA and mRNA associated with hepatic lipid metabolism in term fetal piglets}, booktitle={Swine in Biomedical Research}, author={Man, Chaolai and Xi, Lin and Lima, Hope and Jacobi, Sheila and Resnyk, Chris and Liu, Sunny and Odle, Jack}, year={2014}, pages={108} } @article{drayton_lin_jacobi_shanely_mcintosh_odle_2014, title={Methylated Medium‐ and Long‐Chain Fatty Acids Provide Novel Sources of Anaplerotic Carbon for Fasting or Exercising Mice}, volume={28}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.28.1_supplement.lb438}, DOI={10.1096/fasebj.28.1_supplement.lb438}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Drayton, Josephine and Lin, Xi and Jacobi, Sheila and Shanely, R. and McIntosh, Michael and Odle, Jack}, year={2014}, month={Apr} } @misc{lin_2014, title={Nutritional innovations for alleviating stress--The stress induced by high temperature and malnutrition}, author={Lin, X.}, year={2014} } @misc{lin_odle_2014, title={The Critical Role of Lipid Metabolism in Neonatal Pigs}, author={Lin, X. and Odle, Jack}, year={2014} } @article{odle_lin_jacobi_kim_stahl_2014, title={The Suckling Piglet as an Agrimedical Model for the Study of Pediatric Nutrition and Metabolism}, volume={2}, ISSN={2165-8102 2165-8110}, url={http://dx.doi.org/10.1146/annurev-animal-022513-114158}, DOI={10.1146/annurev-animal-022513-114158}, abstractNote={ The neonatal pig ranks among the most prominent research models for the study of pediatric nutrition and metabolism. Its precocial development at birth affords ready adaptation to artificial rearing systems, and research using this model spans a wide array of nutrients. Sophisticated in vitro and in vivo methodologies supporting both invasive, reduction-science research as well as whole-animal preclinical investigations have been developed. Potential applications may dually benefit both agricultural and medical sciences (e.g., “agrimedical research”). The broad scope of this review is to outline the fundamental elements of the piglet model and to highlight key aspects of relevance to various macronutrients, including lipids, carbohydrates, proteins/amino acids, and calcium/phosphorus. The review examines similarities between piglets and infants and also piglet idiosyncrasies, concluding that, overall, the piglet represents an adaptable and robust model for pediatric nutrition and metabolism research. }, number={1}, journal={Annual Review of Animal Biosciences}, publisher={Annual Reviews}, author={Odle, Jack and Lin, Xi and Jacobi, Sheila K. and Kim, Sung Woo and Stahl, Chad H.}, year={2014}, month={Feb}, pages={419–444} } @article{shen_chuang_martinez_reid_brown_xi_hixson_starnes_mcintosh_2013, title={Conjugated Linoleic Acid Reduces Adiposity and Increases Markers of Browning and Inflammation in White Adipose Tissue of Mice}, volume={27}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.27.1_supplement.640.8}, DOI={10.1096/fasebj.27.1_supplement.640.8}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Shen, Wan and Chuang, Chia‐Chi and Martinez, Kristina and Reid, Tanya and Brown, J. Mark and Xi, Lin and Hixson, Lindsay and Starnes, Joe and McIntosh, Michael}, year={2013}, month={Apr} } @article{shen_chuang_martinez_reid_brown_xi_hixson_hopkins_starnes_mcintosh_2013, title={Conjugated linoleic acid reduces adiposity and increases markers of browning and inflammation in white adipose tissue of mice}, volume={54}, ISSN={0022-2275}, url={http://dx.doi.org/10.1194/jlr.M030924}, DOI={10.1194/jlr.m030924}, number={4}, journal={Journal of Lipid Research}, publisher={Elsevier BV}, author={Shen, Wan and Chuang, Chia-Chi and Martinez, Kristina and Reid, Tanya and Brown, J. Mark and Xi, Lin and Hixson, Lindsay and Hopkins, Robin and Starnes, Joseph and McIntosh, Michael}, year={2013}, month={Apr}, pages={909–922} } @article{price_lin_van heugten_odle_willis_odle_2013, title={Diet physical form, fatty acid chain length, and emulsification alter fat utilization and growth of newly weaned pigs}, volume={91}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/jas.2012-5307}, DOI={10.2527/jas.2012-5307}, number={2}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Price, K. L. and Lin, X. and van Heugten, E. and Odle, R. and Willis, G. and Odle, J.}, year={2013}, month={Feb}, pages={783–792} } @article{herfel_jacobi_lin_jouni_chichlowski_stahl_odle_2013, title={Dietary supplementation of Bifidobacterium longum strain AH1206 increases its cecal abundance and elevates intestinal interleukin-10 expression in the neonatal piglet}, volume={60}, ISSN={0278-6915}, url={http://dx.doi.org/10.1016/j.fct.2013.07.020}, DOI={10.1016/j.fct.2013.07.020}, journal={Food and Chemical Toxicology}, publisher={Elsevier BV}, author={Herfel, Tina M. and Jacobi, Sheila K. and Lin, Xi and Jouni, Zeina E. and Chichlowski, Maciej and Stahl, Chad H. and Odle, Jack}, year={2013}, month={Oct}, pages={116–122} } @article{cabrera_lin_ashwell_moeser_odle_2013, title={Early postnatal kinetics of colostral immunoglobulin G absorption in fed and fasted piglets and developmental expression of the intestinal immunoglobulin G receptor}, volume={91}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/jas.2011-4426}, DOI={10.2527/jas.2011-4426}, number={1}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Cabrera, R. and Lin, X. and Ashwell, M. and Moeser, A. and Odle, J.}, year={2013}, month={Jan}, pages={211–218} } @article{huang_wang_spears_lin_guo_2013, title={Effect of copper on performance, carcass characteristics, and muscle fatty acid composition of meat goat kids}, volume={91}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/jas.2012-5820}, DOI={10.2527/jas.2012-5820}, number={10}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Huang, Y. L. and Wang, Y. and Spears, J. W. and Lin, X. and Guo, C. H.}, year={2013}, month={Oct}, pages={5004–5010} } @article{lovercamp_stewart_lin_flowers_2013, title={Effect of dietary selenium on boar sperm quality}, volume={138}, ISSN={0378-4320}, url={http://dx.doi.org/10.1016/j.anireprosci.2013.02.016}, DOI={10.1016/j.anireprosci.2013.02.016}, number={3-4}, journal={Animal Reproduction Science}, publisher={Elsevier BV}, author={Lovercamp, K.W. and Stewart, K.R. and Lin, X. and Flowers, W.L.}, year={2013}, month={May}, pages={268–275} } @article{liu_chen_li_odle_lin_zhu_pi_hou_hong_shi_et al._2013, title={Fish Oil Alleviates Activation of the Hypothalamic-Pituitary-Adrenal Axis Associated with Inhibition of TLR4 and NOD Signaling Pathways in Weaned Piglets after a Lipopolysaccharide Challenge}, volume={143}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.3945/jn.113.179960}, DOI={10.3945/jn.113.179960}, number={11}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Liu, Y. and Chen, F. and Li, Q. and Odle, J. and Lin, X. and Zhu, H. and Pi, D. and Hou, Y. and Hong, Y. and Shi, H. and et al.}, year={2013}, month={Sep}, pages={1799–1807} } @article{liu_chen_odle_lin_zhu_shi_hou_yin_2013, title={Fish Oil Increases Muscle Protein Mass and Modulates Akt/FOXO, TLR4, and NOD Signaling in Weanling Piglets After Lipopolysaccharide Challenge}, volume={143}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.3945/jn.113.176255}, DOI={10.3945/jn.113.176255}, number={8}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Liu, Yulan and Chen, Feng and Odle, Jack and Lin, Xi and Zhu, Huiling and Shi, Haifeng and Hou, Yongqing and Yin, Jingdong}, year={2013}, month={Jun}, pages={1331–1339} } @inproceedings{lin_lima_odle_2013, title={Improving health of small infants via nutritional epigenetics}, author={Lin, X. and Lima, H. and Odle, J.}, year={2013}, month={Mar} } @inproceedings{odle_lin_jacobi_liu_2013, title={Recent advances in polyunsaturated fatty acid nutrition and metabolism in swine}, author={Odle, J. and Lin, X. and Jacobi, S. and Liu, Y.}, year={2013} } @article{huang_lu_xie_li_li_liu_zhang_xi_luo_2013, title={Relative bioavailabilities of organic zinc sources with different chelation strengths for broilers fed diets with low or high phytate content}, volume={179}, ISSN={["0377-8401"]}, DOI={10.1016/j.anifeedsci.2012.10.010}, number={1-4}, journal={ANIMAL FEED SCIENCE AND TECHNOLOGY}, author={Huang, Y. L. and Lu, L. and Xie, J. J. and Li, S. F. and Li, X. L. and Liu, S. B. and Zhang, L. Y. and Xi, L. and Luo, X. G.}, year={2013}, month={Jan}, pages={144–148} } @article{herfel_jacobi_lin_van heugten_fellner_odle_2013, title={Stabilized rice bran improves weaning pig performance via a prebiotic mechanism}, volume={91}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/jas.2012-5287}, DOI={10.2527/jas.2012-5287}, number={2}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Herfel, T. and Jacobi, S. and Lin, X. and Van Heugten, E. and Fellner, V. and Odle, J.}, year={2013}, month={Feb}, pages={907–913} } @article{bai_xi_drayton_ji_odle_2012, title={Clofibrate increases in vivo fatty acid oxidation by neonatal pigs}, volume={26}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.26.1_supplement.651.5}, DOI={10.1096/fasebj.26.1_supplement.651.5}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Bai, Xiumei and Xi, Lin and Drayton, Josephine and Ji, Cheng and Odle, Jack}, year={2012}, month={Apr} } @misc{bai_xi_drayton_ji_odle_2012, title={Clofibrate increases in vivo fatty acid oxidation by neonatal pigs}, author={Bai, Xiumei and Xi, Lin and Drayton, Josephine and Ji, Cheng and Odle, Jack}, year={2012} } @misc{odle_lin_2012, title={Correlations between infant and pig nutrition and health}, author={Odle, Jack and Lin, X}, year={2012} } @article{liu_chen_odle_lin_jacobi_zhu_wu_hou_2012, title={Fish Oil Enhances Intestinal Integrity and Inhibits TLR4 and NOD2 Signaling Pathways in Weaned Pigs after LPS Challenge}, volume={142}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.3945/jn.112.164947}, DOI={10.3945/jn.112.164947}, number={11}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Liu, Yulan and Chen, Feng and Odle, Jack and Lin, Xi and Jacobi, Sheila K. and Zhu, Huiling and Wu, Zhifeng and Hou, Yongqing}, year={2012}, month={Sep}, pages={2017–2024} } @article{cabrera_lin_campbell_moeser_odle_2012, title={Influence of birth order, birth weight, colostrum and serum immunoglobulin G on neonatal piglet survival}, volume={3}, ISSN={2049-1891}, url={http://dx.doi.org/10.1186/2049-1891-3-42}, DOI={10.1186/2049-1891-3-42}, abstractNote={Abstract Background Intake of colostrum after birth is essential to stimulate intestinal growth and function, and to provide systemic immunological protection via absorption of Immunoglobulin G (IgG). The birth order and weight of 745 piglets (from 75 litters) were recorded during a one-week period of farrowing. Only pigs weighing greater than 0.68 kg birth weight were chosen for the trial. Sow colostrum was collected during parturition, and piglets were bled between 48 and 72 hours post-birth. Piglet serum IgG and colostral IgG concentrations were determined by radial immunodiffusion. Results Sow parity had a significant (P < 0.001) effect on sow colostral IgG concentration, being 5% higher in multiparous females. Sow colostral IgG concentration explained 6% and piglet birth order accounted for another 4% of the variation observed in piglet serum IgG concentration (P < 0.05); however, birth weight had no detectable effect. Piglet serum IgG concentration had both a linear (P < 0.05) and quadratic effect (P < 0.05) on % survival. Piglets with 1,000 mg/dl serum IgG or less (n=24) had a 67% survival; whereas, piglets with IgG concentrations between 2250 to 2500 mg/dl (n=247) had a 91% survival. Birth order had no detectable effect on survival, but birth weight had a positive linear effect (P < 0.05). Piglets weighing 0.9 kg (n = 107) at birth had a 68% survival rate, and those weighing 1.6 kg (n = 158) had an 89% survival. Conclusion We found that the combination of sow colostrum IgG concentration and birth order can account for 10% of the variation of piglet serum IgG concentration and that piglets with less than 1,000 mg/dl IgG serum concentration and weight of 0.9 kg at birth had low survival rate when compared to their larger siblings. The effective management of colostrum uptake in neonatal piglets in the first 24 hrs post-birth may potentially improve survival from birth to weaning. }, number={1}, journal={Journal of Animal Science and Biotechnology}, publisher={Springer Science and Business Media LLC}, author={Cabrera, Rafael A and Lin, Xi and Campbell, Joy M and Moeser, Adam J and Odle, Jack}, year={2012}, month={Dec} } @inbook{lin_azain_odle_2012, title={Lipids and Lipid Utilization in Swine}, url={http://dx.doi.org/10.1002/9781118491454.ch3}, DOI={10.1002/9781118491454.ch3}, booktitle={Sustainable Swine Nutrition}, publisher={Blackwell Publishing Ltd.}, author={Lin, Xi and Azain, Mike and Odle, Jack}, year={2012}, month={Nov}, pages={59–79} } @article{bai_lu_wang_xi_zhang_luo_2012, title={Manganese source affects manganese transport and gene expression of divalent metal transporter 1 in the small intestine of broilers}, volume={108}, ISSN={0007-1145 1475-2662}, url={http://dx.doi.org/10.1017/S0007114511005629}, DOI={10.1017/S0007114511005629}, number={2}, journal={British Journal of Nutrition}, publisher={Cambridge University Press (CUP)}, author={Bai, Shi-Ping and Lu, Lin and Wang, Rui-Lian and Xi, Lin and Zhang, Li-Yang and Luo, Xu-Gang}, year={2012}, month={Jul}, pages={267–276} } @misc{khan_xi_2012, title={The Effect of cofibrate on renal fatty acid oxidation in neonatal pigs}, author={Khan, Imad and Xi, Lin}, year={2012} } @article{xi_matsey_odle_2012, title={The effect of 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) on fatty acid oxidation in hepatocytes isolated from neonatal piglets}, volume={3}, ISSN={2049-1891}, url={http://dx.doi.org/10.1186/2049-1891-3-30}, DOI={10.1186/2049-1891-3-30}, number={1}, journal={Journal of Animal Science and Biotechnology}, publisher={Springer Science and Business Media LLC}, author={Xi, Lin and Matsey, Gary and Odle, Jack}, year={2012}, month={Oct} } @inproceedings{jacobi_moeser_xi_blikslager_odle_2011, title={A porcine model studying prophylaxis and treatment of neonatal enteric disease with long chain PUFA}, booktitle={Swine in Biomedical Research Conference}, author={Jacobi, S.K. and Moeser, A.J. and Xi, L. and Blikslager, A.T. and Odle, J.}, year={2011}, pages={49} } @article{li_lin_lu_xi_wang_hao_zhang_li_luo_2011, title={An estimation of the manganese requirement for broilers from 1 to 21 days of age}, volume={143}, ISSN={0163-4984 1559-0720}, url={http://dx.doi.org/10.1007/s12011-010-8931-7}, DOI={10.1007/s12011-010-8931-7}, number={2}, journal={Biological Trace Element Research}, publisher={Springer Science and Business Media LLC}, author={Li, S. F. and Lin, Y. X. and Lu, L. and Xi, L. and Wang, Z. and Hao, S. and Zhang, L. and Li, K. and Luo, X. G.}, year={2011}, pages={939–948} } @article{jacobi_lin_corl_hess_harrell_odle_2011, title={Dietary Arachidonate Differentially Alters Desaturase-Elongase Pathway Flux and Gene Expression in Liver and Intestine of Suckling Pigs}, volume={141}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.3945/jn.110.127118}, DOI={10.3945/jn.110.127118}, number={4}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Jacobi, Sheila K. and Lin, Xi and Corl, Benjamin A. and Hess, Holly A. and Harrell, Robert J. and Odle, Jack}, year={2011}, month={Feb}, pages={548–553} } @article{lin_bo_oliver_corl_jacobi_oliver_harrell_odle_2011, title={Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs}, volume={22}, ISSN={0955-2863}, url={http://dx.doi.org/10.1016/j.jnutbio.2010.09.002}, DOI={10.1016/j.jnutbio.2010.09.002}, number={11}, journal={The Journal of Nutritional Biochemistry}, publisher={Elsevier BV}, author={Lin, Xi and Bo, Jenny and Oliver, Susan A. Mathews and Corl, Benjamin A. and Jacobi, Sheila K. and Oliver, William T. and Harrell, Robert J. and Odle, Jack}, year={2011}, month={Nov}, pages={1047–1054} } @article{liu_xi_herfel_jacobi_odle_2011, title={Effects of 9‐cis‐retinoic acid on fatty acid oxidation induced by clofibrate in primary cultured heptocytes from newborn pigs}, volume={25}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.25.1_supplement.585.6}, DOI={10.1096/fasebj.25.1_supplement.585.6}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Liu, Yulan and Xi, Lin and Herfel, Tina M. and Jacobi, Sheila K. and Odle, Jack}, year={2011}, month={Apr} } @article{bai_ma_zhao_xi_ji_2011, title={Effects of alpha-lipoic acid supplementation on antioxidative ability and performance of sows and nursing piglets}, volume={96}, ISSN={0931-2439}, url={http://dx.doi.org/10.1111/j.1439-0396.2011.01205.x}, DOI={10.1111/j.1439-0396.2011.01205.x}, number={6}, journal={Journal of Animal Physiology and Animal Nutrition}, publisher={Wiley}, author={Bai, X. M. and Ma, Q. G. and Zhao, L. H. and Xi, L. and Ji, C.}, year={2011}, month={Aug}, pages={955–961} } @article{liu_lu_li_zhang_xi_zhang_luo_2011, title={Effects of supplemental zinc source and level on growth performance, carcass traits, and meat quality of broilers}, volume={90}, ISSN={0032-5791}, url={http://dx.doi.org/10.3382/ps.2010-01215}, DOI={10.3382/ps.2010-01215}, number={8}, journal={Poultry Science}, publisher={Elsevier BV}, author={Liu, Z.H. and Lu, L. and Li, S.F. and Zhang, L.Y. and Xi, L. and Zhang, K.Y. and Luo, X.G.}, year={2011}, month={Aug}, pages={1782–1790} } @article{shields_van heugten_lin_odle_stark_2011, title={Evaluation of the nutritional value of glycerol for nursery pigs}, volume={89}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/jas.2010-3558}, DOI={10.2527/jas.2010-3558}, number={7}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Shields, M. C. and van Heugten, E. and Lin, X. and Odle, J. and Stark, C. S.}, year={2011}, month={Jul}, pages={2145–2153} } @misc{odle_jacobi_lin_2011, title={Piglet Model of Pediatric Nutrition and Metabolism}, author={Odle, J. and Jacobi, S.K. and Lin, X.}, year={2011} } @inproceedings{odle_jacobi_lin_2011, title={Piglet model of pediatric nutrition and metabolism}, booktitle={Swine in Biomedical Research Conference}, author={Odle, J. and Jacobi, S.K. and Lin, X.}, year={2011}, pages={22} } @article{herfel_jacobi_lin_fellner_walker_jouni_odle_2011, title={Polydextrose Enrichment of Infant Formula Demonstrates Prebiotic Characteristics by Altering Intestinal Microbiota, Organic Acid Concentrations, and Cytokine Expression in Suckling Piglets}, volume={141}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.3945/jn.111.143727}, DOI={10.3945/jn.111.143727}, number={12}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Herfel, Tina M. and Jacobi, Sheila K. and Lin, Xi and Fellner, Vivek and Walker, D. Carey and Jouni, Zeina E. and Odle, Jack}, year={2011}, month={Oct}, pages={2139–2145} } @article{herfel_jacobi_lin_walker_russell_stahl_odle_2011, title={Safety of novel Bifidobacterium strains demonstrated in a human infant surrogate, the neonatal pig}, volume={25}, number={584}, journal={FASEB Journal}, author={Herfel, T. and Jacobi, S. and Lin, X. and Walker, C. and Russell, M. and Stahl, C. and Odle, J.}, year={2011}, pages={16} } @article{lin_shim_odle_2010, title={Carnitine palmitoyltransferase I control of acetogenesis, the major pathway of fatty acid β-oxidation in liver of neonatal swine}, volume={298}, ISSN={0363-6119 1522-1490}, url={http://dx.doi.org/10.1152/ajpregu.00634.2009}, DOI={10.1152/ajpregu.00634.2009}, abstractNote={To examine the regulation of hepatic acetogenesis in neonatal swine, carnitine palmitoyltransferase I (CPT I) activity was measured in the presence of varying palmitoyl-CoA (substrate) and malonyl-CoA (inhibitor) concentrations, and [1-14}, number={5}, journal={American Journal of Physiology-Regulatory, Integrative and Comparative Physiology}, publisher={American Physiological Society}, author={Lin, Xi and Shim, Kwanseob and Odle, Jack}, year={2010}, month={May}, pages={R1435–R1443} } @article{huang_lu_xi_luo_liu_2010, title={Effects of age and strain on the expression of leptin receptor, neuropeptide Y and pro-opiomelanocortin in the hypothalamus of young chickens}, volume={51}, ISSN={0007-1668 1466-1799}, url={http://dx.doi.org/10.1080/00071668.2010.508488}, DOI={10.1080/00071668.2010.508488}, number={5}, journal={British Poultry Science}, publisher={Informa UK Limited}, author={Huang, J.X. and Lu, L. and Xi, L. and Luo, X.G. and Liu, B.}, year={2010}, month={Oct}, pages={696–702} } @article{yu_lu_wang_xi_luo_liu_2010, title={Effects of zinc source and phytate on zinc absorption by in situ ligated intestinal loops of broilers}, volume={89}, ISSN={0032-5791}, url={http://dx.doi.org/10.3382/ps.2009-00486}, DOI={10.3382/ps.2009-00486}, number={10}, journal={Poultry Science}, publisher={Elsevier BV}, author={Yu, Y. and Lu, L. and Wang, R.L. and Xi, L. and Luo, X.G. and Liu, B.}, year={2010}, month={Oct}, pages={2157–2165} } @article{herfel_jacobi_lin_walker_jouni_odle_2010, title={Polydextrose enrichment of infant formula acts as a prebiotic by increasing ileal lactobacilli and lactic acid concentration and decreasing pH}, volume={24}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.24.1_supplement.327.7}, DOI={10.1096/fasebj.24.1_supplement.327.7}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Herfel, Tina M and Jacobi, Sheila and Lin, X and Walker, D C and Jouni, Z E and Odle, Jack}, year={2010}, month={Apr} } @article{brown_lin_van heugten_harrell_hanson_odle_2010, title={Production of value-added pork by enrichment with omega-3 fatty acids}, volume={88}, number={E-Suppl. 3}, journal={Journal of Animal Science}, author={Brown, C. and Lin, X. and van Heugten, E. and Harrell, R. and Hanson, D. and Odle, J.}, year={2010}, pages={72} } @article{cabrera_lin_taro_ashwell_moeser_odle_2010, title={The effect of feeding sow colostrum on IgG absorption, intestinal morphology and expression of IgG receptor (FcRn) and β2-microglobulin (β2M) in neonatal piglets}, volume={88}, number={E-Suppl. 3}, journal={Journal of Animal Science}, author={Cabrera, R. and Lin, X. and Taro, A. and Ashwell, M. and Moeser, A. and Odle, J.}, year={2010}, pages={100} } @inproceedings{cabrera_lin_shim_inskeep_campbell_odle_2009, title={Birth Order, Birth Weight, Sow Colostrum IgG and Pig IgG Concentration and their effects on Neonatal Piglet Survival}, author={Cabrera, R. and Lin, X. and Shim, K. and Inskeep, T. and Campbell, J. and Odle, J.}, year={2009} } @article{shim_xi_jacobi_odle_2009, title={Clofibrate induces expression of hepatic genes encoding fatty acid oxidation and ketogenesis enzymes in pigs during early postnatal development}, volume={23}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.23.1_supplement.903.3}, DOI={10.1096/fasebj.23.1_supplement.903.3}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Shim, Kwanseob and Xi, Lin and Jacobi, Sheila and Odle, Jack}, year={2009}, month={Apr} } @inproceedings{shim_xi_jacobi_odle_2009, title={Clofibrate treatment up-regulates hepatic gene expression encoding fatty acid oxidation and ketogenesis enzymes in liver of pigs during early postnatal development}, author={Shim, Kwanseob and Xi, Lin and Jacobi, Shelia and Odle, Jack}, year={2009} } @article{jacobi_lin_corl_odle_2009, title={Ontogeny of the desaturase‐elongase pathway in neonatal pigs fed arachidonic acid}, volume={23}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.23.1_supplement.lb430}, DOI={10.1096/fasebj.23.1_supplement.lb430}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Jacobi, Sheila K. and Lin, Xi and Corl, Benjamin and Odle, Jack}, year={2009}, month={Apr} } @article{herfel_jacobi_lin_walker_jouni_odle_2009, title={Safety evaluation of polydextrose in infant formula using a suckling piglet model}, volume={47}, ISSN={0278-6915}, url={http://dx.doi.org/10.1016/j.fct.2009.03.039}, DOI={10.1016/j.fct.2009.03.039}, number={7}, journal={Food and Chemical Toxicology}, publisher={Elsevier BV}, author={Herfel, T.M. and Jacobi, S.K. and Lin, X. and Walker, D.C. and Jouni, Z.E. and Odle, J.}, year={2009}, month={Jul}, pages={1530–1537} } @article{corl_mathews oliver_lin_oliver_ma_harrell_odle_2008, title={Conjugated Linoleic Acid Reduces Body Fat Accretion and Lipogenic Gene Expression in Neonatal Pigs Fed Low- or High-Fat Formulas}, volume={138}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.1093/jn/138.3.449}, DOI={10.1093/jn/138.3.449}, number={3}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Corl, Benjamin A. and Mathews Oliver, Susan A. and Lin, Xi and Oliver, William T. and Ma, Yongxi and Harrell, Robert J. and Odle, Jack}, year={2008}, month={Mar}, pages={449–454} } @article{brown_goodband_tokach_dritz_nelssen_minton_higgins_lin_odle_woodworth_et al._2008, title={Effects of feeding l-carnitine to gilts through day 70 of gestation on litter traits and the expression of insulin-like growth factor system components and l-carnitine concentration in foetal tissues}, volume={92}, ISSN={0931-2439 1439-0396}, url={http://dx.doi.org/10.1111/j.1439-0396.2007.00762.x}, DOI={10.1111/j.1439-0396.2007.00762.x}, number={6}, journal={Journal of Animal Physiology and Animal Nutrition}, publisher={Wiley}, author={Brown, K. R. and Goodband, R. D. and Tokach, M. D. and Dritz, S. S. and Nelssen, J. L. and Minton, J. E. and Higgins, J. J. and Lin, X. and Odle, J. and Woodworth, J. C. and et al.}, year={2008}, month={Dec}, pages={660–667} } @article{hess_corl_lin_jacobi_harrell_blikslager_odle_2008, title={Enrichment of Intestinal Mucosal Phospholipids with Arachidonic and Eicosapentaenoic Acids Fed to Suckling Piglets Is Dose and Time Dependent}, volume={138}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.3945/jn.108.094136}, DOI={10.3945/jn.108.094136}, number={11}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Hess, Holly A. and Corl, Benjamin A. and Lin, Xi and Jacobi, Sheila K. and Harrell, Robert J. and Blikslager, Anthony T. and Odle, Jack}, year={2008}, month={Nov}, pages={2164–2171} } @article{xi_brown_woodworth_shim_johnson_odle_2008, title={Maternal Dietary L-Carnitine Supplementation Influences Fetal Carnitine Status and Stimulates Carnitine Palmitoyltransferase and Pyruvate Dehydrogenase Complex Activities in Swine}, volume={138}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.3945/jn.108.095638}, DOI={10.3945/jn.108.095638}, number={12}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Xi, Lin and Brown, Kelly and Woodworth, Jason and Shim, Kwanseob and Johnson, Bradley and Odle, Jack}, year={2008}, month={Dec}, pages={2356–2362} } @article{herfel_jacobi_lin_walker_jouni_odle_2008, title={Polydextrose enrichment of infant formula elicits prebiotic effects without altering systemic growth and development of suckling piglets.}, volume={22}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.22.2_supplement.724}, DOI={10.1096/fasebj.22.2_supplement.724}, number={S2}, journal={The FASEB Journal}, publisher={Wiley}, author={Herfel, Tina Marie and Jacobi, S. K. and Lin, X. and Walker, D. C. and Jouni, Z. E. and Odle, J.}, year={2008}, month={Apr}, pages={724–724} } @inproceedings{herfel_jacobi_lin_odle_2008, title={Stabilized rice bran improves weaning pig growth performance when fed in an antibiotic-free diet}, author={Herfel, T.M. and Jacobi, S.K. and Lin, X. and Odle, J.}, year={2008} } @article{shim_xi_herfel_odle_2008, title={The effects of clofibrate on malonyl‐CoA inhibition of carnitine pamitoyltransferase I (CPT I) and fatty acid oxidation in liver of neonatal pigs}, volume={22}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.22.1_supplement.1091.9}, DOI={10.1096/fasebj.22.1_supplement.1091.9}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Shim, Kwanseob and Xi, Lin and Herfel, Tina and Odle, Jack}, year={2008}, month={Mar} } @article{xi_jacobi_odle_2008, title={Transplacental induction of fatty acid oxidation in newborn pigs by clofibrate}, volume={22}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.22.1_supplement.1091.8}, DOI={10.1096/fasebj.22.1_supplement.1091.8}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Xi, Lin and Jacobi, Sheila and Odle, Jack}, year={2008}, month={Mar} } @inbook{lin_corl_odle_2007, title={Idiosyncrasies of piglet lipid metabolism and their relationship to postnatal mortality}, booktitle={Paradigms in pig science}, publisher={Nottingham University Press}, author={Lin, X. and Corl, B.A. and Odle, J.}, editor={Wiseman, J.Editor}, year={2007}, pages={187–206} } @inproceedings{price_xi_van heugten_willis_odle_2007, title={Improving fat utilization by the weanling pig: effects of emulsification, diet physical form and fatty-acid-chain-length on growth performance}, author={Price, K. and Xi, L. and van Heugten, E. and Willis, G. and Odle, J.}, year={2007} } @article{lyvers peffer_lin_jacobi_gatlin_woodworth_odle_2007, title={Ontogeny of Carnitine Palmitoyltransferase I Activity, Carnitine-Km, and mRNA Abundance in Pigs throughout Growth and Development}, volume={137}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.1093/jn/137.4.898}, DOI={10.1093/jn/137.4.898}, number={4}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Lyvers Peffer, Pasha and Lin, Xi and Jacobi, Sheila K. and Gatlin, Lori Averette and Woodworth, Jason and Odle, Jack}, year={2007}, month={Apr}, pages={898–903} } @misc{lin_odle_2006, title={Cardiomyocyte Isolation, preparation, properties and applications}, author={Lin, X. and Odle, J.}, year={2006} } @article{xi_brown_woodworth_johnson_odle_2006, title={Effects of maternal dietary L‐carnitine on fetal carnitine status as measured by tissue carnitine accumulation and kinetics of carnitine palmitoyltransferase in fetal pigs}, volume={20}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.20.4.a170-c}, DOI={10.1096/fasebj.20.4.a170-c}, number={4}, journal={The FASEB Journal}, publisher={Wiley}, author={Xi, Lin and Brown, Kelly R. and Woodworth, Jason C. and Johnson, Bradley J. and Odle, Jack}, year={2006}, month={Mar} } @article{dicklin_robinson_lin_odle_2006, title={Ontogeny and chain-length specificity of gastrointestinal lipases affect medium-chain triacylglycerol utilization by newborn pigs}, volume={84}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/2006.844818x}, DOI={10.2527/2006.844818x}, number={4}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Dicklin, M. E. and Robinson, J. L. and Lin, X. and Odle, J.}, year={2006}, month={Apr}, pages={818–825} } @article{hess_corl_lin_averette gatlin_phillips_harrell_blikslager_odle_2006, title={Prophylactic enrichment of enterocyte phospholipids with polyunsaturated fatty acids fed to suckling piglets}, volume={20}, ISSN={0892-6638 1530-6860}, url={http://dx.doi.org/10.1096/fasebj.20.4.a170-b}, DOI={10.1096/fasebj.20.4.a170-b}, number={4}, journal={The FASEB Journal}, publisher={Wiley}, author={Hess, Holly Aline and Corl, Ben A. and Lin, Xi and Averette Gatlin, Lori A. and Phillips, Oulayvanh T. and Harrell, Robert J. and Blikslager, Anthony T. and Odle, Jack}, year={2006}, month={Mar} } @article{see_armstrong_matzat_belstra_mckeith_rincker_xi_odle_culbertson_hering_et al._2005, title={Effect of ractopamine feeding level on growth performance and carcass composition}, journal={Journal of Animal Science}, author={See, M.T. and Armstrong, T.A. and Matzat, P.D. and Belstra, B.A. and McKeith, F. and Rincker, P. and Xi, L. and Odle, J. and Culbertson, M. and Hering, W. and et al.}, year={2005} } @inbook{odle_lyvers-peffer_lin_2005, place={New York}, title={Hepatic fatty acid oxidation and ketogenesis in young pigs}, volume={3}, ISSN={1877-1823}, url={http://dx.doi.org/10.1016/s1877-1823(09)70016-5}, DOI={10.1016/s1877-1823(09)70016-5}, number={C}, booktitle={Biology of Growing Animals}, publisher={Elsevier}, author={Odle, J. and Lyvers-Peffer, P. and Lin, X.}, editor={Burrin, D. and Mersmann, H.Editors}, year={2005}, pages={219–234} } @article{peffer_lin_odle_2005, title={Hepatic β-oxidation and carnitine palmitoyltransferase I in neonatal pigs after dietary treatments of clofibric acid, isoproterenol, and medium-chain triglycerides}, volume={288}, ISSN={0363-6119 1522-1490}, url={http://dx.doi.org/10.1152/ajpregu.00822.2004}, DOI={10.1152/ajpregu.00822.2004}, abstractNote={A suckling piglet model was used to study nutritional and pharmacologic means of stimulating hepatic fatty acid β-oxidation. Newborn pigs were fed milk diets containing either long- or medium-chain triglycerides (LCT or MCT). The long-chain control diet was supplemented further with clofibric acid (0.5%) or isoproterenol (40 ppm), and growth was monitored for 10–12 days. Clofibrate increased rates of hepatic peroxisomal and mitochondrial β-oxidation of [1-14}, number={6}, journal={American Journal of Physiology-Regulatory, Integrative and Comparative Physiology}, publisher={American Physiological Society}, author={Peffer, Pasha Lyvers and Lin, Xi and Odle, Jack}, year={2005}, month={Jun}, pages={R1518–R1524} } @article{lin_house_odle_2005, title={Ontogeny and kinetics of carnitine palmitoyltransferase in liver and skeletal muscle of the domestic felid ()}, volume={16}, ISSN={0955-2863}, url={http://dx.doi.org/10.1016/j.jnutbio.2004.12.012}, DOI={10.1016/j.jnutbio.2004.12.012}, number={6}, journal={The Journal of Nutritional Biochemistry}, publisher={Elsevier BV}, author={Lin, X and House, R and Odle, J}, year={2005}, month={Jun}, pages={331–338} } @misc{lin_odle_2004, title={Fatty acid oxidation in neonatal pigs}, author={Lin, X. and Odle, J.}, year={2004} } @article{lin_lyvers peffer_woodworth_odle_2004, title={Ontogeny of carnitine biosynthesis in pigs, inferred from gamma-butyrobetaine hydroxylase activity}, journal={FASEB Journal}, author={Lin, X. and Lyvers Peffer, P. and Woodworth, J. and Odle, J}, year={2004} } @article{lyvers-peffer_lin_averette gatlin_woodworth_odle_2004, title={Ontogeny of mitochondrial carnitine palmitoyltransferase I in porcine liver and skeletal muscle}, volume={82}, number={Suppl. 1}, journal={Journal of Animal Science}, author={Lyvers-Peffer, P. and Lin, X. and Averette Gatlin, L. and Woodworth, J. and Odle, J.}, year={2004}, pages={20} } @article{qiao_lin_odle_whittaker_van kempen_2004, title={Refining in vitro digestibility assays: Fractionation of digestible and indigestible peptides}, volume={82}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/2004.8261669x}, DOI={10.2527/2004.8261669x}, number={6}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Qiao, Y. and Lin, X. and Odle, J. and Whittaker, A. and van Kempen, T. A. T. G.}, year={2004}, month={Jun}, pages={1669–1677} } @article{lin_odle_2003, title={Changes in Kinetics of Carnitine Palmitoyltransferase in Liver and Skeletal Muscle of Dogs (Canis familiaris) throughout Growth and Development}, volume={133}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.1093/jn/133.4.1113}, DOI={10.1093/jn/133.4.1113}, number={4}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Lin, Xi and Odle, Jack}, year={2003}, month={Apr}, pages={1113–1119} } @article{mathews_oliver_lin_odle_harrell_2003, title={Conjugated linoleic acid reduces total body fat while not affecting the metabolism of essential fatty acids in the liver, brain or skeletal muscle of neonatal pigs}, volume={17}, number={5}, journal={FASEB Journal}, author={Mathews, S.A. and Oliver, W.T. and Lin, X. and Odle, J. and Harrell, R.J.}, year={2003} } @article{oliver_lin_odle_harrell_2003, title={Conjugated linoleic acid reduces total body fat, while not affecting the metabolism of essential fatty acids in the liver, brain or skeletal muscle of neonatal pigs}, volume={17}, number={4}, journal={FASEB Journal}, author={Oliver, W.T. and Lin, X. and Odle, J. and Harrell, R.J.}, year={2003}, pages={A752} } @article{bo_lin_mathews oliver_harrell_odle_2003, title={Dietary conjugated kinoleic acid (CLA) reduces long-chain polyunsaturated fatty acid (LCPUFA) biosynthesis in brain and liver tissues of neonatal pigs}, volume={16}, journal={FASEB Journal}, author={Bo, J. and Lin, X. and Mathews Oliver, S.A. and Harrell, R.J. and Odle, J.}, year={2003}, pages={A223} } @article{tiffany_spears_xi_horton_2003, title={Influence of dietary cobalt source and concentration on performance, vitamin B12 status, and ruminal and plasma metabolites in growing and finishing steers}, volume={81}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/2003.81123151x}, DOI={10.2527/2003.81123151x}, number={12}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Tiffany, M. E. and Spears, J. W. and Xi, L. and Horton, J.}, year={2003}, month={Dec}, pages={3151–3159} } @article{gatlin_see_larick_lin_odle_2002, title={Conjugated Linoleic Acid in Combination with Supplemental Dietary Fat Alters Pork Fat Quality}, volume={132}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.1093/jn/131.10.3105}, DOI={10.1093/jn/131.10.3105}, number={10}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Gatlin, L. Averette and See, M. T. and Larick, D. K. and Lin, X. and Odle, J.}, year={2002}, month={Oct}, pages={3105–3112} } @article{evens_lin_odle_mcintosh_2002, title={Conjugated lenoleic acid increase oleic acid oxidation in 3T3-L1 preadipocytes}, volume={16}, number={5}, journal={FASEB Journal}, author={Evens, M. and Lin, X. and Odle, J. and McIntosh, M.}, year={2002}, pages={A1016} } @article{mathews_oliver_lin_phillips_brown_odle_harrell_2002, title={Essential fatty acid deficiency in piglets decreases b-oxidation of 14C linoleate and 14C palmitate in both liver and brain tissues}, volume={16}, number={4}, journal={FASEB Journal}, author={Mathews, S.A. and Oliver, W.T. and Lin, X. and Phillips, O.T. and Brown, J.A. and Odle, J. and Harrell, R.J.}, year={2002}, pages={A233} } @article{lvvers-peffer_lin_harrell_odle_2002, title={Induction of post-natal carnitine palmitoyltransferase activity and hepatic b-oxidation in piglets}, volume={16}, number={4}, journal={FASEB Journal}, author={Lvvers-Peffer, P. and Lin, X. and Harrell, R. and Odle, J.}, year={2002}, pages={A632} } @article{heo_lin_han_odle_2002, title={Medium-Chain Fatty Acids but Not L-Carnitine Accelerate the Kinetics of [14C]Triacylglycerol Utilization by Colostrum-Deprived Newborn Pigs}, volume={132}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.1093/jn/132.7.1989}, DOI={10.1093/jn/132.7.1989}, number={7}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Heo, Kinam N. and Lin, Xi and Han, In K. and Odle, Jack}, year={2002}, month={Jul}, pages={1989–1994} } @article{evans_lin_odle_mcintosh_2002, title={Trans-10, Cis-12 Conjugated Linoleic Acid Increases Fatty Acid Oxidation in 3T3-L1 Preadipocytes}, volume={132}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.1093/jn/132.3.450}, DOI={10.1093/jn/132.3.450}, number={3}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Evans, M. and Lin, X. and Odle, J. and McIntosh, M.}, year={2002}, month={Mar}, pages={450–455} } @article{heo_odle_lin_kempen_han_2001, title={Determination of Carnitine Renal Threshold and Effect of Medium-Chain Triglycerides on Carnitine Profiles in Newborn Pigs}, volume={14}, ISSN={1011-2367 1976-5517}, url={http://dx.doi.org/10.5713/ajas.2001.237}, DOI={10.5713/ajas.2001.237}, number={2}, journal={Asian-Australasian Journal of Animal Sciences}, publisher={Asian Australasian Association of Animal Production Societies}, author={Heo, K. N. and Odle, J. and Lin, X. and Kempen, T. A. T. G. van and Han, In K.}, year={2001}, month={Feb}, pages={237–242} } @book{heo_odle_lin_van kempen_han_2001, title={Effect of L-carnitine and medium-chain triglyceride on plasma and urinary in newborn piglets}, author={Heo, K. and Odle, J. and Lin, X. and van Kempen, T. and Han, I.K.}, year={2001} } @article{mathews_harrell_oliver_brown_phillips_lin_odle_diersen-schade_2001, title={Effects of long_chain polyunsaturated fatty acids (LCPUFA) on body composition and tissue accretion in the neonatal pig}, volume={79}, number={Suppl. 1}, journal={Journal of Animal Science}, author={Mathews, S.A. and Harrell, R.J. and Oliver, W.T. and Brown, J.A. and Phillips, O. and Lin, X. and Odle, J. and Diersen-Schade, D.A.}, year={2001}, pages={398} } @book{heo_lin_odle_han_2001, title={Kinetics of carnitine palmitoyltrasferase I in liver and skeletal muscle of young pigs}, author={Heo, K. and Lin, X. and Odle, J. and Han, I.K.}, year={2001} } @article{engle_spears_l._edens_2000, title={Dietary copper effects on lipid metabolism and circulating catecholamine concentrations in finishing steers}, volume={78}, DOI={10.2527/2000.78102737x}, number={10}, journal={Journal of Animal Science}, author={Engle, T. E. and Spears, J. W. and L. and Edens, F. W.}, year={2000}, pages={2737–2744} } @inproceedings{heo_odle_lin_van kempen_han_2000, title={Effect of L-carnitine and emulsified trioctanolyglycerol on kinetics of plasma carnitine and urinary carnitine excretion in colostrum-deprived newborn piglets}, booktitle={Proceedings of the 2000 International Symposium on Recent Advances in Animal Nutrition}, author={Heo, K.N. and Odle, J. and Lin, X. and van Kempen, T. and Han, I.K.}, year={2000}, pages={445 447} } @article{heo_lin_odle_han_2000, title={Kinetics of Carnitine Palmitoyltransferase-I Are Altered by Dietary Variables and Suggest a Metabolic Need for Supplemental Carnitine in Young Pigs}, volume={130}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.1093/jn/130.10.2467}, DOI={10.1093/jn/130.10.2467}, number={10}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Heo, Kinam and Lin, Xi and Odle, Jack and Han, In K.}, year={2000}, month={Oct}, pages={2467–2470} } @article{lin_odle_buddington_lepine_2000, title={Kinetics of carnitine palmitoyltransferase in frozen feline liver}, volume={14}, journal={FASEB Journal}, author={Lin, X. and Odle, J. and Buddington, R. and Lepine, A.}, year={2000}, pages={A208} } @article{mastey_lin_odle_2000, title={The effect of glucagons and insulin on b-oxidation of 1-14C-palmitate by piglet hepatocyted in primary culture}, journal={Journal of animal science}, publisher={J. Animal Sci}, author={Mastey, G. and Lin, X. and Odle, J.}, year={2000} } @article{odle_heo_lin_2000, title={The role of carnitine and betaine in lean growth modulation of swine}, volume={13}, number={2000}, journal={Asian-Australasian Journal of Animal Sciences}, author={Odle, J. and Heo, K.N. and Lin, X.}, year={2000}, pages={386–395} } @article{lin_odle_buddington_lepine_1999, title={Acetyl-Coenzyme A carboxylase (ACC) activity in the liver and adipose tissue during development of the canine}, volume={13}, number={5}, journal={FASEB Journal}, author={Lin, X. and Odle, J. and Buddington, R. and Lepine, A.}, year={1999}, pages={A903} } @article{odle_heo_lin_han_1999, title={Carnitine palmitoyltransferase I activity and carnitine concentration in liver and skeletal muscle of 20 kg pigs}, volume={13}, number={5}, journal={FASEB Journal}, author={Odle, J. and Heo, K.N. and Lin, X. and Han, In K.}, year={1999}, pages={A908} } @inproceedings{lin_matsey_heo_odle_1999, title={The effect of 5-aminoimidaole-4-caboxamide ribonucleoside (AICAR) on hepatic fatty acid oxidation in neonatal piglets}, booktitle={10th Annual institute of Nutrition Research Symposium Proceedings}, author={Lin, X. and Matsey, G.G. and Heo, K. and Odle, J.}, year={1999}, pages={P16} } @inproceedings{mareskes_odle_lin_gomez_black_1998, title={Effect of L-alanyl-glutamine on rotaviral enteritis of neonatal piglets}, author={Mareskes, C. and Odle, J. and Lin, X. and Gomez, G. and Black, B.}, year={1998} } @article{lin_odle_buddington_lepine_1998, title={Ontogeny and kinetics of carnitine acyltransferase activity in the canine}, journal={FASEB Journal}, author={Lin, X. and Odle, J. and Buddington, R. and Lepine, A.}, year={1998} } @inproceedings{matsey_lin_odle_1997, title={Effects of glucagon on piglet hepatocytes in primary culture}, author={Matsey, G.J. and Lin, X. and Odle, J.}, year={1997} } @article{adams_lin_yu_odle_drackley_1997, title={Hepatic fatty acid metabolism in pigs and rats: major differences in endproducts, O2 uptake, and beta-oxidation}, volume={272}, ISSN={0363-6119 1522-1490}, url={http://dx.doi.org/10.1152/ajpregu.1997.272.5.R1641}, DOI={10.1152/ajpregu.1997.272.5.r1641}, abstractNote={ Models of mammalian hepatic lipid metabolism are based largely on observations made in adult rats, emphasizing ketogenesis as a primary adjunct to mitochondrial beta-oxidation. Studies using piglets have illustrated the divergent nature of intermediary metabolism in this model, wherein ketogenesis and beta-oxidation are small and acetogenesis is an important route of fuel carbon flux. To clarify potential species differences in hepatic lipid metabolism and its control, we compared O2 consumption and metabolic end products in fasted pig and rat liver homogenates treated with 1-[14C]C16:0. Carboxyl carbon accumulation in acid-soluble products (ASP) plus CO2 was threefold greater and O2 consumption was twofold greater in rats (P < 0.05). Unlike rats, pigs showed negligible carboxyl carbon accumulation in ketone bodies (3-7% of ASP), whereas acetate was a carboxyl carbon reservoir in both animals (17-31% of ASP in pigs). Malonate increased (approximately 2-fold) and antimycin/rotenone decreased (40-60%) radiolabel accumulation in acetate. These data concur with the hypotheses that comparatively low hepatic beta-oxidative flux in piglets is partially related to a smaller metabolic rate and that substantial acetogenesis occurs intramitochondrially in both pigs and rats. }, number={5}, journal={American Journal of Physiology-Regulatory, Integrative and Comparative Physiology}, publisher={American Physiological Society}, author={Adams, S. H. and Lin, X. and Yu, X. X. and Odle, J. and Drackley, J. K.}, year={1997}, month={May}, pages={R1641–R1646} } @article{yu_drackley_odle_lin_1997, title={Response of Hepatic Mitochondrial and Peroxisomal β-Oxidation to Increasing Palmitate Concentrations in Piglets}, volume={72}, ISSN={1661-7800 1661-7819}, url={http://dx.doi.org/10.1159/000244495}, DOI={10.1159/000244495}, number={5}, journal={Neonatology}, publisher={S. Karger AG}, author={Yu, Xing Xian and Drackley, James K. and Odle, Jack and Lin, Xi}, year={1997}, pages={284–292} } @article{lin_adams_odle_1996, title={Acetate represents a major product of heptanoate and octanoate β-oxidation in hepatocytes isolated from neonatal piglets}, volume={318}, ISSN={0264-6021 1470-8728}, url={http://dx.doi.org/10.1042/bj3180235}, DOI={10.1042/bj3180235}, abstractNote={An experiment was conducted to explore the nature of the radiolabel distribution in acid-soluble products (ASPs) resulting from the oxidation of [1-14C]C7:0 or C8:0 by isolated piglet hepatocytes. The differences between odd and even chain-length and the impacts of valproate and malonate upon the rate of β-oxidation and ASP characteristics were tested. A minor amount of fatty acid carboxyl carbon (⩽ 10% of organic acids identified by radio-HPLC) accumulated in ketone bodies regardless of chain-length or inhibitor used. In all cases, acetate represented the major reservoir of carboxyl carbon, accounting for 60–70% of radiolabel in identified organic acids. Cells given [1-14C]C7:0 accumulated 85% more carboxyl carbon in Krebs cycle intermediates when compared with C8:0, while accumulation in acetate was unaffected. The results are consistent with the hypothesis that anaplerosis from odd-carbon fatty acids affects the oxidative fate of fatty acid carbon. The piglet appears unique in that non-ketogenic routes of fatty acid carbon flow (i.e. acetogenesis) predominate in the liver of this species.}, number={1}, journal={Biochemical Journal}, publisher={Portland Press Ltd.}, author={Lin, Xi and Adams, Sean H. and Odle, Jack}, year={1996}, month={Aug}, pages={235–240} } @inproceedings{odle_lin_see_1996, title={New technology to improve survival of neonatal pigs}, booktitle={Proceedings of the International Symposium for the 20th Anniversary of Korean Society of Animal Nutrition}, author={Odle, J. and Lin, X. and See, T.}, year={1996}, pages={89–98} } @inproceedings{xi_odle_yu_1995, title={Acetate production from [U-14C]-palmitate by heart and liver mitochondria isolated from piglets and rabbits}, booktitle={Proceedings of the International Symposium Swine in Biomedical Research}, author={Xi, Lin and Odle, J. and Yu, X.X.}, year={1995}, pages={128} } @article{odle_lin_van kampen_drackley_adams_1995, title={Carnitine palmitoyltransferase modulation of hepatic fatty acid metabolism and radio-HPLC Evidence for low ketogenesis in neonatal pigs}, volume={125}, number={10}, journal={Journal of Nutrition}, author={Odle, J. and Lin, X. and van Kampen, Theo A.T.G. and Drackley, James K. and Adams, Sean H.}, year={1995}, month={Oct}, pages={2541–2549} } @article{drackley_yu_lin_odle_1995, title={Effects of palmitate concentration on mitochondrial and peroxisomal ß-oxidation in piglet and adult rat liver}, journal={FASEB Journal}, author={Drackley, J. K. and Yu, X.X. and Lin, Xi and Odle, J.}, year={1995} } @article{yu_lin_drackley_odle_1995, title={Fatty acid oxidation in pig liver and kidney during postnatal development: The role of peroxisomes}, journal={FASEB Journal}, author={Yu, X. X. and Lin, Xi and Drackley, J.K. and Odle, J.}, year={1995} } @article{hansen_drackley_berger_grum_cremin_lin_odle_1995, title={Prenatal androgenization of lambs: II. Metabolism in adipose tissue and liver}, volume={73}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/1995.7361701x}, DOI={10.2527/1995.7361701x}, number={6}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Hansen, L. R. and Drackley, J. K. and Berger, L. L. and Grum, D. E. and Cremin, J. D., Jr. and Lin, X. and Odle, J.}, year={1995}, month={Jun}, pages={1701–1712} } @article{lin_odle_1995, title={Regulation of fatty acid oxidation in mitochondria of neonatal pigs via carnitine palmitoyltransferase I}, volume={73}, number={suppl. 1}, journal={Journal of Animal Science}, author={Lin, Xi and Odle, J.}, year={1995}, pages={77} } @article{lin_adams_odle_1994, title={Acetate is a product of 1-carbon flux during ß-oxidation of hepatanoate and octanoate in hepatocytes isolated from neonatal pigs}, journal={FASEB Journal}, author={Lin, Xi and Adams, S.H. and Odle, J.}, year={1994}, pages={A734} } @book{adams_lin_odle_1994, title={Do newborn piglets have limited ability to use fat for energy? Development of hepatic ketogenesis in neonatal piglets}, journal={Research Investment Report}, institution={National Pork Producers Council}, author={Adams, S. H. and Lin, Xi and Odle, J.}, year={1994}, pages={89–98} } @article{odle_lin_wieland_van kempen_1994, title={Emulsification and Fatty Acid Chain Length Affect the Kinetics of [14C]-Medium-Chain Triacylglycerol Utilization by Neonatal Piglets}, volume={124}, ISSN={0022-3166 1541-6100}, url={http://dx.doi.org/10.1093/jn/124.1.84}, DOI={10.1093/jn/124.1.84}, number={1}, journal={The Journal of Nutrition}, publisher={Oxford University Press (OUP)}, author={Odle, Jack and Lin, Xi and Wieland, Teresa M. and van Kempen, Theo A.T.G.}, year={1994}, month={Jan}, pages={84–93} } @article{adams_odle_lin_van kempen_1994, title={Plasma acetate, impaired ketogenesis, & chain-shortening of C8:0 in day-old pigs fasted from birth}, journal={FASEB Journal}, author={Adams, S. H. and Odle, J. and Lin, Xi and van Kempen, T.A.T.G.}, year={1994}, pages={A733} } @article{adams_lin_odle_van kempen_1993, title={Acetogenesis replaces ketogenesis during ß-oxidation in neonatal pigs}, volume={33}, journal={American Zoologist}, author={Adams, S. H. and Lin, Xi and Odle, J. and van Kempen, T.A.T.G.}, year={1993}, pages={37A} } @article{odle_lin_wieland_van kempen_1993, title={Effect of emulsification on the oxidation of triacylglycerols containing (1-14C)-hexanoate or octanoate by newborn pigs}, volume={7}, journal={FASEB Journal}, author={Odle, J. and Lin, Xi and Wieland, T.M. and Van Kempen, T.A.T.G.}, year={1993}, pages={A883} } @article{wieland_lin_odle_1993, title={Emulsification and fatty-acid chain length affect the utilization of medium-chain triglycerides by neonatal pigs}, volume={71}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/1993.7171869x}, DOI={10.2527/1993.7171869x}, number={7}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Wieland, Teresa M. and Lin, Xi and Odle, Jack}, year={1993}, month={Jul}, pages={1869–1874} } @article{lin_van kempen_odle_1993, title={Production of dicarboxylic acids (DCA) in newborn pigs infused with various medium-chain fatty acids}, volume={7}, journal={FASEB Journal}, author={Lin, Xi and van Kempen, T.A.T.G. and Odle, J.}, year={1993}, pages={A384} } @book{odle_lin_wieland_van kempen_zijllstr_1993, title={Unique energy supplements for newborn piglets}, institution={National Pork Producers Council}, author={Odle, J. and Lin, Xi and Wieland, T.M. and van Kempen, T.A.T.G. and Zijllstr, R.}, year={1993} } @article{wieland_lin_odle_1993, title={Utilization of medium-chain triglycerides by neonatal pigs: effects of emulsification and dose delivered}, volume={71}, ISSN={0021-8812 1525-3163}, url={http://dx.doi.org/10.2527/1993.7171863x}, DOI={10.2527/1993.7171863x}, number={7}, journal={Journal of Animal Science}, publisher={Oxford University Press (OUP)}, author={Wieland, Teresa M. and Lin, Xi and Odle, Jack}, year={1993}, month={Jul}, pages={1863–1868} } @book{wieland_lin_van kempen_odle_1992, title={Enhancement of medium-chain triglyceride (MCT) utilization by neonatal piglets}, institution={National Pork Producers Council}, author={Wieland, T. M. and Lin, Xi and van Kempen, T.A.T.G. and Odle, J.}, year={1992}, pages={53–57} } @inproceedings{odle_wieland_lin_1992, title={Improving piglet survival by nutritional means: Efforts to enhance the efficacy of medium-chain triglycerides}, booktitle={American Society of Animal Science Midwestern Section}, author={Odle, J. and Wieland, T.M. and Lin, Xi.}, year={1992}, pages={61} } @article{lin_odle_van kempen_drackley_1992, title={The role of carnitine acyltransferase (CAT) in control of hepatic lipid metabolism in developing small-for-estational-age piglets}, journal={FASEB Journal}, author={Lin, Xi and Odle, J. and van Kempen, T.A.T.G. and Drackley, J.K.}, year={1992}, pages={A1383} } @inbook{yang_ding_zhu_lin_gong_1991, place={Beijing, China}, title={Analysis and quality control of feedstuffs}, booktitle={National teaching materials for institution of higher learning, colleges and universities}, publisher={BAU press}, author={Yang, S. and Ding, J.L. and Zhu, Y.Q. and Lin, Xi and Gong, L.M.}, year={1991} } @phdthesis{lin_rong_1990, title={The interaction between vitamin A and E in the immune system of chicks}, school={Part I}, author={Lin, Xi and Rong, Y.}, year={1990} } @phdthesis{lin_rong_1990, title={The interrelationship between vitamin A and E in absorption and transportation}, author={Lin, Xi and Rong, Y.}, year={1990} } @article{lin_cheng_manz_rong_1988, title={Determination of Vitamin A in compounded feeds, concentrated supplements and feed additives with the help of HPLC}, volume={14}, number={2}, journal={Acta Agriculturae Universitatis Pekinensis}, author={Lin, Xi and Cheng, J. and Manz, U. and Rong, Y.}, year={1988}, pages={29} } @article{ji_lin_scheurmann_rong_1988, title={Determination of amino acid content in feedstuffs using the HPLC}, volume={14}, number={3}, journal={Acta Agriculturae Universitatis Pekinensis}, author={Ji, C. and Lin, Xi and Scheurmann, S.E. and Rong, Y.}, year={1988}, pages={37} } @article{lin_zhang_yang_1988, title={Nitrogen metabolism of piglets on different dietary protein levels}, number={4}, journal={Chinese Journal of Animal Science}, author={Lin, Xi and Zhang, Y. and Yang, S.}, year={1988}, pages={5–9} } @article{lin_zhang_yang_1987, title={The influence of dietary lysine and protein levels on productive performance and carcass quality of growing pigs}, volume={13}, number={3}, journal={Acta Agriculturae Universitatis Pekinensis}, author={Lin, Xi and Zhang, Y. and Yang, S.}, year={1987} } @article{zhang_niu_lin_huang_yang_1984, title={Nitrogen retention of Landrace * Beijing Black pigs}, journal={Progress of Scientific Research}, publisher={BAU}, author={Zhang, Y. and Niu, W.S. and Lin, Xi and Huang, Z. and Yang, S.}, year={1984}, pages={100} } @article{niu_lin_huang_zhang_yang_1983, title={Requirements of lysine and protein for Landrace * Beijing Black growing-finishing pigs}, journal={Progress of Scientific Research}, publisher={BAU}, author={Niu, W. S. and Lin, Xi and Huang, Z. and Zhang, Y. and Yang, S.}, year={1983}, pages={97} }