Xudong Zhang
Works (23)
Updated: July 5th, 2023 15:37
2021 article
Bioorthogonal catalytic patch
Chen, Z., Li, H., Bian, Y., Wang, Z., Chen, G., Zhang, X., … Gu, Z. (2021, May 10). NATURE NANOTECHNOLOGY.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacokinetics; Antineoplastic Agents / pharmacology; Catalysis; Drug Delivery Systems; Hep G2 Cells; Humans; Melanoma, Experimental; Metal Nanoparticles / chemistry; Metal Nanoparticles / therapeutic use; Mice; Palladium / chemistry; Palladium / pharmacokinetics; Palladium / pharmacology; Prodrugs / chemistry; Prodrugs / pharmacokinetics; Prodrugs / pharmacology; Titanium / chemistry; Titanium / pharmacokinetics; Titanium / pharmacology
Source: Web Of Science
Added: June 10, 2021
2020 journal article
Engineered PD-L1-Expressing Platelets Reverse New-Onset Type 1 Diabetes
ADVANCED MATERIALS, 32(26).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; immune tolerance; platelets; programmed death-ligand 1 (PD-L1); type 1 diabetes (T1D)
MeSH headings : Animals; B7-H1 Antigen / genetics; B7-H1 Antigen / metabolism; Blood Glucose / analysis; CD8-Positive T-Lymphocytes / cytology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; Diabetes Mellitus, Type 1 / pathology; Diabetes Mellitus, Type 1 / therapy; Diabetes Mellitus, Type 1 / veterinary; Genetic Engineering; Immune Tolerance; Insulin / blood; Insulin-Secreting Cells / cytology; Insulin-Secreting Cells / immunology; Insulin-Secreting Cells / metabolism; Megakaryocyte Progenitor Cells / cytology; Megakaryocyte Progenitor Cells / metabolism; Megakaryocyte Progenitor Cells / transplantation; Mice; Mice, Inbred NOD; T-Lymphocytes, Regulatory / cytology; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism
Source: Web Of Science
Added: June 8, 2020
2019 journal article
A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
ACS NANO, 13(4), 4354–4360.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; microneedle; exosome; keratin; hair regrowth; transdermal drug delivery
MeSH headings : Animals; Cell Line; Delayed-Action Preparations / chemistry; Drug Delivery Systems / instrumentation; Equipment Design; Hair / chemistry; Hair / drug effects; Hair / growth & development; Hair Follicle / drug effects; Hair Follicle / growth & development; Humans; Injections, Subcutaneous; Keratins / chemistry; Mice, Inbred C57BL; Transdermal Patch
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Bioresponsive Protein Complex of aPD1 and aCD47 Antibodies for Enhanced Immunotherapy
NANO LETTERS, 19(8), 4879–4889.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Drug delivery; immunotherapy; immune checkpoint blockade; bioresponsive; nanomedicine
MeSH headings : Animals; Antibodies, Monoclonal / immunology; Antibodies, Monoclonal / therapeutic use; Antineoplastic Agents, Immunological / immunology; Antineoplastic Agents, Immunological / therapeutic use; CD47 Antigen / immunology; Female; Immunotherapy; Melanoma / immunology; Melanoma / therapy; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor / immunology; Reactive Oxygen Species / immunology; Tumor Microenvironment / drug effects
Source: Web Of Science
Added: September 3, 2019
2019 journal article
Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs
SCIENCE ADVANCES, 5(7).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems; Insulin / administration & dosage; Mice; Molecular Structure; Polymers / chemical synthesis; Polymers / chemistry; Swine
advances.sciencemag.org (publisher PDF)
Source: Web Of Science
Added: August 19, 2019
2019 journal article
In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
NATURE NANOTECHNOLOGY, 14(1), 89-+.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Biocompatible Materials / chemistry; Calcium Carbonate / chemistry; Female; Fibrin / chemistry; Gels / chemistry; Humans; Immunity; Immunotherapy / methods; Luminescent Measurements; Melanoma, Experimental / pathology; Mice, Inbred C57BL; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Neoplasm Recurrence, Local / pathology; Neoplasms / pathology; Neoplasms / surgery; Phagocytosis
Source: Web Of Science
Added: January 21, 2019
2019 journal article
Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy
NANO RESEARCH, 12(6), 1313–1320.
co-author countries:
United States of America 🇺🇸
author keywords: liquid metal; melanin nanoparticles; nanomedicine; shape-controlled synthesis; photothermal therapy
Source: Web Of Science
Added: June 17, 2019
2018 journal article
Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy
ACS NANO, 12(6), 5995–6005.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: salmonella; polydopamine; hypoxia targeting; photothermal therapy; malignant melanoma
MeSH headings : Animals; Antineoplastic Agents / adverse effects; Antineoplastic Agents / metabolism; Antineoplastic Agents / pharmacology; Cell Survival / drug effects; Hypoxia / metabolism; Indoles / adverse effects; Indoles / metabolism; Indoles / pharmacology; Lasers; Melanoma, Experimental / metabolism; Melanoma, Experimental / pathology; Melanoma, Experimental / therapy; Mice; Phototherapy; Polymers / adverse effects; Polymers / metabolism; Polymers / pharmacology; Salmonella / growth & development; Salmonella / metabolism; Tissue Distribution; Tumor Cells, Cultured
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery
SMALL, 14(14).
co-author countries:
United States of America 🇺🇸
author keywords: diabetes; drug delivery; insulin; microneedles; stimuli-responsive
MeSH headings : Animals; Drug Delivery Systems / methods; Humans; Hydrogen Peroxide / chemistry; Hydrogen-Ion Concentration; Insulin / administration & dosage; Insulin / chemistry; Mice; Oxidation-Reduction
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy
NATURE BIOMEDICAL ENGINEERING, 2(11), 831–840.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antibodies / chemistry; Antibodies / immunology; Blood Platelets / chemistry; Blood Platelets / cytology; Blood Platelets / metabolism; Cell Line, Tumor; Chemokines / metabolism; Cytokines / metabolism; Disease Models, Animal; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells / chemistry; Hematopoietic Stem Cells / cytology; Hematopoietic Stem Cells / metabolism; Leukemia / therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Receptor / deficiency; Programmed Cell Death 1 Receptor / genetics; Programmed Cell Death 1 Receptor / immunology; T-Lymphocytes / cytology; T-Lymphocytes / immunology; T-Lymphocytes / metabolism
Source: Web Of Science
Added: November 26, 2018
2018 journal article
Engineering PD-1-Presenting Platelets for Cancer Immunotherapy
NANO LETTERS, 18(9), 5716–5725.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Drug delivery; platelet; immune checkpoint blockade; immunotherapy; nanomedicine
Source: Web Of Science
Added: October 16, 2018
2018 journal article
In situ formed reactive oxygen species-responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy
SCIENCE TRANSLATIONAL MEDICINE, 10(429).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Cell Line, Tumor; Combined Modality Therapy; Deoxycytidine / analogs & derivatives; Deoxycytidine / therapeutic use; Female; Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry; Immunotherapy / methods; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor / metabolism; Gemcitabine
Source: Web Of Science
Added: August 6, 2018
2018 journal article
PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy
ADVANCED MATERIALS, 30(22).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: cancer immunotherapy; cell therapy; drug delivery; immune checkpoint blockade; nanomedicine
MeSH headings : Humans; Immunotherapy; Lymphocytes, Tumor-Infiltrating; Neoplasms / therapy; Programmed Cell Death 1 Receptor; T-Lymphocytes; Tumor Microenvironment
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Phosphorylcholine-based stealthy nanocapsules decorating TPGS for combatting multi-drug-resistant cancer
ACS Biomaterials-Science & Engineering, 4(5), 1679–1686.
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
The mechanism of lauric acid-modified protein nanocapsules escape from intercellular trafficking vesicles and its implication for drug delivery
Drug Delivery, 25(1), 985–994.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
A melanin-mediated cancer immunotherapy patch
SCIENCE IMMUNOLOGY, 2(17).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Cancer Vaccines / immunology; Cancer Vaccines / metabolism; Cell Line, Tumor; Dendritic Cells / immunology; Dendritic Cells / metabolism; Female; Immunotherapy / instrumentation; Immunotherapy / methods; Infrared Rays; Kaplan-Meier Estimate; Melanins / immunology; Melanins / metabolism; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Needles; Neoplasms, Experimental / immunology; Neoplasms, Experimental / pathology; Neoplasms, Experimental / therapy; Transdermal Patch; Tumor Burden / immunology
Source: Web Of Science
Added: August 6, 2018
2017 journal article
A pH-sensitive methenamine mandelate-loaded nanoparticle induces DNA damage and apoptosis of cancer cells
Acta Biomaterialia, 62, 246–256.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Investigation and intervention of autophagy to guide cancer treatment with nanogels
NANOSCALE, 9(1), 150–163.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Autophagy; Chloroquine / administration & dosage; Doxorubicin / administration & dosage; Drug Delivery Systems; Endocytosis; Endosomes; Exocytosis; Female; Gels; Humans; MCF-7 Cells; Mice; Mice, SCID; Nanoparticles; Neoplasms, Experimental / drug therapy; Rhodamines; Xenograft Model Antitumor Assays; rab GTP-Binding Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Synthetic beta cells for fusion-mediated dynamic insulin secretion
Nature Chemical Biology, 14(1), 86–93.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Artificial Cells; Biomimetic Materials / chemistry; Blood Glucose / analysis; Cell Engineering / methods; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Hydrogen-Ion Concentration; Insulin / blood; Insulin / metabolism; Insulin Secretion; Insulin-Secreting Cells / metabolism; Male; Membrane Fusion; Mice, Inbred C57BL
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Systematic investigation on the intracellular trafficking network of polymeric nanoparticles
Nanoscale, 9(9), 3269–3282.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Iron oxide nanoparticles induce autophagosome accumulation through multiple mechanisms: Lysosome impairment, mitochondrial damage, and ER stress
Molecular Pharmaceutics, 13(7), 2578–2587.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
intracellular trafficking network of protein nanocapsules: endocytosis, exocytosis and autophagy
Theranostics, 6(12), 2099–2113.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Core-Shell Microneedle Gel for Self-Regulated Insulin Delivery
Wang, J. Q., Ye, Y. Q., Yu, J. C., Kahkoska, A. R., Zhang, X. D., Wang, C., … Gu, Z. ACS Nano, 12(3), 2466–2473.
Source: NC State University Libraries
Added: August 6, 2018
